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Yingyun Wang
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Journal Articles

Abstract 1927: Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors

Urszula N. Wasko, Jingjing Jiang, Yingyun Wang, Lorenzo Tomassoni, Lingyan Jiang, Marie Menard, Alvaro Curiel-Garcia, Tanner C. Dalton, Margo Orlen, Cole Edwards, Clint Stalnecker, Julien Dilly, Stephanie Chang, Stephen A. Sastra, Carmine F. Palermo, Timour Baslan, Sha Tian, Matthew Holderfield, Elsa Quintana, Zhengping Wang, Jacqueline A. Smith, Andrea Califano, David Wildes, Andrew J. Aguirre, Robert H. Vonderheide, Ben Z. Stanger, Scott W. Lowe, Channing J. Der, Mallika Singh, Kenneth P. Olive
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1927.
https://doi.org/10.1158/1538-7445.AM2024-1927
Published: 22 March 2024
View article titled, Abstract 1927: Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors
Journal Articles

Abstract B101: Tumor-selective inhibition of active RAS in pancreatic ductal adenocarcinoma

Urszula N. Wasko, Jingjing Jiang, Lorenzo Tomassoni, Yingyun Wang, Bianca Lee, Margo Orlen, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Steven A. Sastra, Carmine F. Palermo, Stephanie Chang, Andrew J. Aguirre, Channing J. Der, Robert H. Vonderheide, Ben Z. Stanger, Andrea Califano, Mallika Singh, Kenneth P. Olive
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): B101.
https://doi.org/10.1158/1538-7445.PANCA2023-B101
Published: 16 January 2024
View article titled, Abstract B101: Tumor-selective inhibition of active RAS in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3597: Direct targeting of KRASG12X mutant cancers with RMC-6236, a first-in-class, RAS-selective, orally bioavailable, tri-complex RASMULTI(ON) inhibitor

Elena S. Koltun, Meghan A. Rice, W. Clay Gustafson, David Wilds, Jingjing Jiang, Bianca J. Lee, Zhengping Wang, Stephanie Chang, Mike Flagella, Yunming Mu, Nuntana Dinglasan, Nicole Nasholm, James W. Evans, Yingyun Wang, Kyle Seamon, Yang Liu, Cristina Blaj, John Knox, Rebecca Freilich, Elsa Quintana, Jim Cregg, Alun Bermingham, Adrian L. Gill, Jacqueline Am Smith, Mallika Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3597.
https://doi.org/10.1158/1538-7445.AM2022-3597
Published: 15 June 2022
View article titled, Abstract 3597: Direct targeting of KRAS<sup>G12X</sup> mutant cancers with RMC-6236, a first-in-class, RAS-selective, orally bioavailable, tri-complex RAS<sup>MULTI</sup>(ON) inhibitor
Journal Articles

Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF

Wenlin Shao, Yuji M. Mishina, Yun Feng, Giordano Caponigro, Vesselina G. Cooke, Stacy Rivera, Yingyun Wang, Fang Shen, Joshua M. Korn, Lesley A. Mathews Griner, Gisele Nishiguchi, Alice Rico, John Tellew, Jacob R. Haling, Robert Aversa, Valery Polyakov, Richard Zang, Mohammad Hekmat-Nejad, Payman Amiri, Mallika Singh, Nicholas Keen, Michael P. Dillon, Emma Lees, Savithri Ramurthy, William R. Sellers, Darrin D. Stuart
Journal: Cancer Research
Cancer Res (2018) 78 (6): 1537–1548.
https://doi.org/10.1158/0008-5472.CAN-17-2033
Published: 14 March 2018
View article titled, Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF
Open the PDF for Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF in another window
Includes: Supplementary data
Journal Articles

Vasculature development on xenograph and syngeneic mouse tumor models: A contrast-enhanced MRI study

Yi-Shan Yang, Steven Choi, Yingyun Wang, Samira Guccione
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 53.
Published: 15 April 2006
View article titled, Vasculature development on xenograph and syngeneic mouse tumor models: A contrast-enhanced MRI study
Journal Articles

A novel targeted nanoparticle-based antiangiogenic therapy on brain tumor - MicroPET and MRI study on a rat glioblastoma model

Yi-Shan Yang, Steven Choi, Yingyun Wang, Samira Guccione
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 895.
Published: 15 April 2006
View article titled, A novel targeted nanoparticle-based antiangiogenic therapy on brain tumor - MicroPET and MRI study on a rat glioblastoma model
Journal Articles

Image guided proteome analysis of human glioblastoma multiforme by two-dimensional differential gel electrophoresis

Gongyi Shi, Yingyun Wang, Yi-Shan Yang, Samira Guccione, Ron Homer, Griff Harsh, Scott Atlas, Mark Bednarski
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1204.
Published: 01 April 2004
View article titled, Image guided proteome analysis of human glioblastoma multiforme by two-dimensional differential gel electrophoresis