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Journal Articles

Abstract 1986: p53/FBXL20 axis negatively regulates the protein stability of PR55α, a PP2A regulatory subunit

Ying Yan, Lepakshe Madduri, Nichole Brandquist, Chitra Palanivel, Sumin Zhou, Charles Enke, Michel Ouellette

Cancer Res (2021) 81 (13_Supplement): 1986.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1986

Published: 01 July 2021

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Journal Articles

Abstract P5-11-20: Efficacy observation of 306 patients with fulvestrant 500mg treatment in hormone-receptor positive HER2 negative metastasis breast cancer, a real world study

Wen Lei, Huiping Li, Guohong Song, Ruyan Zhang, Ran Ran, Ying Yan

Cancer Res (2020) 80 (4_Supplement): P5-11-20.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-P5-11-20

Published: 15 February 2020

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Journal Articles

Abstract 4366: The small GTPase Rac1 controls the stability of the Yes-associated protein 1 (YAP1) independently of the LATS1/2 kinases and SCF-βTRCP ubiquitin ligase

Chitra Palanivel, Bailey Gabler, Ying Yan, Surinder K. Batra, Michel M. Ouellette

Cancer Res (2018) 78 (13_Supplement): 4366.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4366

Published: 01 July 2018

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Journal Articles

Abstract 2175: Considerations in PDX mouse trial design and their relevance to human clinical trial outcomes

Jingjing Jiang, Ying Yan, Tingting Tan, Wei Du, Jiali Gu, Ling Qiu, Katherine Ye, Zhenyu Gu

Cancer Res (2018) 78 (13_Supplement): 2175.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2175

Published: 01 July 2018

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Journal Articles

Abstract 3139: In vivo functional analyses of cancer gene variants for cancer driver identification and drug discovery

Jingjing Jiang, Tengfei Yu, Ying Yan, Wei Du, Tingting Tan, Xuqin Yang, Jiali Gu, Ling Qiu, Xin K. Ye, Zhenyu Gu

Cancer Res (2017) 77 (13_Supplement): 3139.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3139

Published: 01 July 2017

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Journal Articles

Abstract 755: Supporting precision cancer treatment decision with functional evaluation of cancer gene mutations and variants

Jingjing Jiang, Zhongguang Luo, Jia Wei, Guanglei Zhuang, Song Yi, Ying Yan, Tengfei Yu, Wei Du, Tingting Tan, Ling Qiu, Jiali Gu, Xin K. Ye, Jie Liu, Zhenyu Gu

Cancer Res (2017) 77 (13_Supplement): 755.

DOI: https://doi.org/10.1158/1538-7445.AM2017-755

Published: 01 July 2017

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Journal Articles

Abstract 5762: PR55-alpha associated PP2A promotes pancreatic tumorigenesis

Ying Yan, Ashley L. Hein, Parthasarathy Seshacharyulu, Satyanarayana Rachagani, Yuri M. Sheinin, Michel M. Ouellette, Moorthy P. Ponnusamy, Surinder K. Batra

Cancer Res (2017) 77 (13_Supplement): 5762.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5762

Published: 01 July 2017

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Journal Articles

Abstract 3982: Prediction and selection of cancer drug treatments using personalized tumor models or models with matching genomic profiles

Jingjing Jiang, Ying Yan, Zhongguang Luo, Jia He, Tengfei Yu, Wei Du, Xuqin Yang, Jiali Gu, Xin K. Ye, Guanglei Zhuang, Jie Liu, Zhenyu Gu

Cancer Res (2016) 76 (14_Supplement): 3982.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3982

Published: 15 July 2016

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Journal Articles

Abstract 395: Patient stratification and drug combination strategy based on drug response and genomic information from PDX clinical trials (PCTs)

Jingjing Jiang, Tengfei Yu, Ying Yan, Wei Du, Tingting Tan, Xuqin Yang, Jiali Gu, Xin K. Ye, Zhenyu Gu

Cancer Res (2016) 76 (14_Supplement): 395.

DOI: https://doi.org/10.1158/1538-7445.AM2016-395

Published: 15 July 2016

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Journal Articles

Abstract 1669: Inhibition of the Rac1/PAK pathway sensitizes pancreatic cancer cells to gamma-irradiation

Michel M. Ouellette, Surinder K. Batra, Ying Yan

Cancer Res (2016) 76 (14_Supplement): 1669.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1669

Published: 15 July 2016

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Journal Articles

PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling

Ashley L. Hein, Parthasarathy Seshacharyulu, Satyanarayana Rachagani, Yuri M. Sheinin, Michel M. Ouellette, Moorthy P. Ponnusamy, Marc C. Mumby, Surinder K. Batra, Ying Yan

Cancer Res (2016) 76 (8): 2243–2253.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2119

Published: 14 April 2016

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Includes: Supplementary data

Journal Articles

Abstract 1476: Effect of target therapies in liver cancer PDX tumor models: Response, resistance and predictive biomarkers

Tengfei Yu, Ying Yan, Wei Du, Liang Hua, Xuqin Yang, Tingting Tan, Jiali Gu, Jingjing Jiang, Xin K. Ye, Zhenyu Gu

Cancer Res (2015) 75 (15_Supplement): 1476.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1476

Published: 01 August 2015

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Journal Articles

Abstract 3222: Biomarker discovery through bioinformatic analysis of genomic profiles of PDX models with different responses to cancer therapies

Jingjing Jiang, Tengfei Yu, Ying Yan, Wei Du, Tingting Tan, Xuqin Yang, Jiali Gu, Liang Hua, Katherine Xin Ye, Zhenyu Gu

Cancer Res (2015) 75 (15_Supplement): 3222.

DOI: https://doi.org/10.1158/1538-7445.AM2015-3222

Published: 01 August 2015

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Journal Articles

Abstract 1210: A patient derived xenograft tumor model platform for “mouse trials”

Ying Yan, Tengfei Yu, Wei Du, Guosheng Tong, Yuefei Yang, Tingting Tan, Xuqin Yang, Zhenhua Liu, Jiali Gu, Liang Hua, Wei Zhang, Xin K. Ye, Zhenyu Gu

Cancer Res (2014) 74 (19_Supplement): 1210.

DOI: https://doi.org/10.1158/1538-7445.AM2014-1210

Published: 01 October 2014

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Journal Articles

Abstract 1212: Studying cancer drug resistance in patient derived xenograft tumor models

Tengfei Yu, Ying Yan, Wei Du, Yuefei Yang, Tingting Tan, Xuqin Yang, Jiali Gu, Liang Hua, Xin K. Ye, Zhenyu Gu

Cancer Res (2014) 74 (19_Supplement): 1212.

DOI: https://doi.org/10.1158/1538-7445.AM2014-1212

Published: 01 October 2014

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Journal Articles

Abstract 5298: Two distinctive single nucleotide polymorphisms determine liver metastases responses to docetaxel plus thiotepa for metastatic breast cancer patients.

Jing Yu, Ningning Dong, Ying Yan, Bin Shao, Lijun Di, Guohong Song, Li Che, Jun Jia, Hanfang Jiang, Xu Liang, Yulin Zhu, Chaoying Wang, Jie Zahng, Budong Zhu, Xinna Zhou, Xiaoli Wang, Huabing Yang, Jun Ren, Herbert Kim Lyerly

Cancer Res (2013) 73 (8_Supplement): 5298.

DOI: https://doi.org/10.1158/1538-7445.AM2013-5298

Published: 15 April 2013

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Journal Articles

Abstract 2041: Her2/Neu has an essential role for the gamma-irradiation-induced ERK1/2 signaling activation and G2/M checkpoint response

Ying Yan, Patrick M. Greer, Ryan H. Kolb, Kenneth H. Cowan

Cancer Res (2012) 72 (8_Supplement): 2041.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2041

Published: 15 April 2012

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Journal Articles

Abstract #2485: ERK1/2 signaling plays an important role in the topoisomerase II inhibitor induced G2/M checkpoint response

Ryan Kolb, Ying Yan, Ken Cowan

Cancer Res (2009) 69 (9_Supplement): 2485.

Published: 01 May 2009

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Journal Articles

Abstract #LB-177: Phosphatase 2A plays an essential role in \#947;-irradiation-induced G2/M checkpoint response

Ying Yan, Phu Cao, Eric Nagengast, Ryan Kolb, Claudine Black, Kenneth Cowan

Cancer Res (2009) 69 (9_Supplement): LB-177.

Published: 01 May 2009

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Journal Articles

γ-Irradiation–Induced DNA Damage Checkpoint Activation Involves Feedback Regulation between Extracellular Signal-Regulated Kinase 1/2 and BRCA1

Ying Yan, Claudine P. Black, Phu T. Cao, Jamie L. Haferbier, Ryan H. Kolb, Rebecca S. Spieker, Alexandra M. Ristow, Kenneth H. Cowan

Cancer Res (2008) 68 (13): 5113–5121.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-5818

Published: 01 July 2008

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NARROW

Abstract 1986: p53/FBXL20 axis negatively regulates the protein stability of PR55α, a PP2A regulatory subunit

Abstract P5-11-20: Efficacy observation of 306 patients with fulvestrant 500mg treatment in hormone-receptor positive HER2 negative metastasis breast cancer, a real world study

Abstract 4366: The small GTPase Rac1 controls the stability of the Yes-associated protein 1 (YAP1) independently of the LATS1/2 kinases and SCF-βTRCP ubiquitin ligase

Abstract 2175: Considerations in PDX mouse trial design and their relevance to human clinical trial outcomes

Abstract 3139: In vivo functional analyses of cancer gene variants for cancer driver identification and drug discovery

Abstract 755: Supporting precision cancer treatment decision with functional evaluation of cancer gene mutations and variants

Abstract 5762: PR55-alpha associated PP2A promotes pancreatic tumorigenesis

Abstract 3982: Prediction and selection of cancer drug treatments using personalized tumor models or models with matching genomic profiles

Abstract 395: Patient stratification and drug combination strategy based on drug response and genomic information from PDX clinical trials (PCTs)

Abstract 1669: Inhibition of the Rac1/PAK pathway sensitizes pancreatic cancer cells to gamma-irradiation

PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling

Abstract 1476: Effect of target therapies in liver cancer PDX tumor models: Response, resistance and predictive biomarkers

Abstract 3222: Biomarker discovery through bioinformatic analysis of genomic profiles of PDX models with different responses to cancer therapies

Abstract 1210: A patient derived xenograft tumor model platform for “mouse trials”

Abstract 1212: Studying cancer drug resistance in patient derived xenograft tumor models

Abstract 5298: Two distinctive single nucleotide polymorphisms determine liver metastases responses to docetaxel plus thiotepa for metastatic breast cancer patients.

Abstract 2041: Her2/Neu has an essential role for the gamma-irradiation-induced ERK1/2 signaling activation and G2/M checkpoint response

Abstract #2485: ERK1/2 signaling plays an important role in the topoisomerase II inhibitor induced G2/M checkpoint response

Abstract #LB-177: Phosphatase 2A plays an essential role in \#947;-irradiation-induced G2/M checkpoint response

γ-Irradiation–Induced DNA Damage Checkpoint Activation Involves Feedback Regulation between Extracellular Signal-Regulated Kinase 1/2 and BRCA1

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