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Journal Articles

Abstract 6646: Fibroblast growth factor receptor signaling modulates cholesterol storage in a SOAT1-dependent manner to promote mammary tumor cell invasion

Jennifer E. Tuokkola, Lyndsay E. Reese, Ying Wang, Christine H. O'Connor, Annisa H. Rumahorbo, Kathryn L. Schwertfeger
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6646.
https://doi.org/10.1158/1538-7445.AM2025-6646
Published: 21 April 2025
View articletitled, Abstract 6646: Fibroblast growth factor receptor signaling modulates cholesterol storage in a SOAT1-dependent manner to promote mammary tumor cell invasion
Journal Articles

Abstract 1645: Developing first-in-class AR-V7/AR-fl molecular glue degrader to revolutionize prostate cancer therapeutics

CheukMan Cherie Au, Michelle Naidoo, Catrina Estrella, Prerna Vatsa, Ying Wang, Zhao Wang, David M. Nanus, Urko del Castillo, Paraskevi Giannakakou
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1645.
https://doi.org/10.1158/1538-7445.AM2025-1645
Published: 21 April 2025
View articletitled, Abstract 1645: Developing first-in-class AR-V7/AR-fl molecular glue degrader to revolutionize prostate cancer therapeutics
Journal Articles

Abstract 1106: RNA-based risk model for nasopharyngeal carcinoma distant metastasis

Zhaozheng Hou, Ping Feng, Kazi Anisha Islam, Songran Liu, Ying Wang, Yingpei Zhang, Michael King-yung Chung, Ngar-Woon Kam, Zi-Lu Huang, Victor Ho-Fun Lee, Anne WM Lee, Dora LW Kwong, Wai-Tong Ng, Yun-Fei Xia, Wei Dai
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1106.
https://doi.org/10.1158/1538-7445.AM2025-1106
Published: 21 April 2025
View articletitled, Abstract 1106: RNA-based risk model for nasopharyngeal carcinoma distant metastasis
Journal Articles

Abstract 211: Epstein-Barr virus (EBV)‒human host chromatin interactions rearrange spatial DNA genome organisation and hijack KDM5B to distant metastasis proneness in EBV-associated nasopharyngeal carcinoma (NPC)

Lai Shun Dittman Chung, Zhaozheng Hou, Ying Wang, Kazi Anisha Islam, Songran Liu, Jiayan Liu, Larry Ka-Yue Chow, Cyrus Pakk-Ting Chak, Yingpei Zhang, Lanqi Gong, Karl Kui-Wai Cheng, Zhuoyou Yu, Ping Feng, Zilu Huang, Roger Kai-Cheong Ngan, Xinyuan Guan, Wai-Tong Ng, Zhonghua Liu, Anna Chi-Man Tsang, Dora Lai-Wan Kwong, Annie Wing-Mui Lee, Victor Ho-Fun Lee, Honglin Chen, Yunfei Xia, Wei Dai
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 211.
https://doi.org/10.1158/1538-7445.AM2025-211
Published: 21 April 2025
View articletitled, Abstract 211: Epstein-Barr virus (EBV)‒human host chromatin interactions rearrange spatial DNA genome organisation and hijack KDM5B to distant metastasis proneness in EBV-associated nasopharyngeal carcinoma (NPC)
Journal Articles

Abstract 1600: Tracking adaptation and response to targeted therapies in EGFR-mutant non-small cell lung cancer

Regina Hoo, Aaron Tan, Dawn Lau, Komal Gupta, Kenneth Chow, Jia Chi Yeo, Lan Ying Wang, Poh Sheng Joe Yeong, Anders J. Skanderup, Daniel S. Tan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1600.
https://doi.org/10.1158/1538-7445.AM2025-1600
Published: 21 April 2025
View articletitled, Abstract 1600: Tracking adaptation and response to targeted therapies in EGFR-mutant non-small cell lung cancer
Journal Articles

Abstract 2282: Genetic architecture of breast cancer across diverse populations: Assessing heritability, genetic correlation, and polygenicity

James L. Li, Maria Zanti, Jacob Williams, Om Jahagirdar, Guochong Jia, Qiang Hu, Jean-Tristan Brandenburg, Li Yan, Weang-Kee Ho, Jingmei Li, José P. Miranda, Devika Godbole, Julie-Alexia Dias, Leila Dorling, Wenlong C. Chen, Nicholas Boddicker, Ying Wang, Alicia Martin, Martin J. Zhang, Yan Zhang, Joe Dennis, Esther M. John, Gabriela Torres-Mejia, Larry Kushi, Jeffrey Weitzel, Susan L. Neuhausen, Luis Carvajal-Carmona, Christopher Haiman, Elad Ziv, Laura Fejerman, Wei Zheng, Dezheng Huo, Douglas Easton, Nilanjan Chatterjee, Peter Kraft, Montserrat Garcia-Closas, Wendy Wong, Kyriaki Michailidou, Qianqian Zhu, Diptavo Dutta, Thomas U. Ahearn, Haoyu Zhang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2282.
https://doi.org/10.1158/1538-7445.AM2025-2282
Published: 21 April 2025
View articletitled, Abstract 2282: Genetic architecture of breast cancer across diverse populations: Assessing heritability, genetic correlation, and polygenicity
Journal Articles

Abstract 2308: Sustained adherence to the American Cancer Society guideline for diet and physical activity for cancer prevention and 8-year all cancer risk: an emulated target trial in the Cancer Prevention Study-II Nutrition Cohort

Valeria Elahy, Marjorie L. McCullough, Yu-Han Chiu, Alpa V. Patel, Erika Rees-Punia, Clara Bodelon, Anita R. Peoples, Ying Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2308.
https://doi.org/10.1158/1538-7445.AM2025-2308
Published: 21 April 2025
View articletitled, Abstract 2308: Sustained adherence to the American Cancer Society guideline for diet and physical activity for cancer prevention and 8-year all cancer risk: an emulated target trial in the Cancer Prevention Study-II Nutrition Cohort
Journal Articles

Abstract 1251: Decoding tumour evolution and relapse drivers in EGFR mutant NSCLC in never smokers

Komal Gupta, Dawn Lau Pingxi, Ngak Leng Sim, Kenneth Chow, Lan Ying Wang, Mengyuan Pang, Stephanie Saw, Wanjin Hong, Anders Martin Jacobsen Skanderup, Regina Hoo, Daniel Shao Weng Tan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1251.
https://doi.org/10.1158/1538-7445.AM2025-1251
Published: 21 April 2025
View articletitled, Abstract 1251: Decoding tumour evolution and relapse drivers in EGFR mutant NSCLC in never smokers
Journal Articles

Abstract 7419: Polygenic risk scores and risk of second cancers among older adult cancer survivors

Clara Bodelon, Adriana Lori, Christina C. Newton, Ying Wang, Parichoy Pal Choudhury, Hyuna Sung, Ahmedin Jemal, Lauren R. Teras, Alpa V. Patel
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7419.
https://doi.org/10.1158/1538-7445.AM2025-7419
Published: 21 April 2025
View articletitled, Abstract 7419: Polygenic risk scores and risk of second cancers among older adult cancer survivors
Journal Articles

Abstract 5288: Identification of cancer cells with metastatic potential in nasopharyngeal carcinoma through spatial multi-omics analysis

Songran Liu, Zhaozheng Hou, Kazi Anisha Islam, Yingpei Zhang, Larry Ka-Yue Chow, Ying Wang, Ping Feng, Michael King Yung Chung, Kiu-Wai Cheng, Dittman Lai-Shun Chung, Yunfei Xia, Wei Dai
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5288.
https://doi.org/10.1158/1538-7445.AM2025-5288
Published: 21 April 2025
View articletitled, Abstract 5288: Identification of cancer cells with metastatic potential in nasopharyngeal carcinoma through spatial multi-omics analysis
Journal Articles

Molecular Characterization and Classification of HER2-Positive Breast Cancer Inform Tailored Therapeutic Strategies

Yu-Wei Li, Lei-Jie Dai, Xiang-Rong Wu, Shen Zhao, Yu-Zheng Xu, Xi Jin, Yi Xiao, Ying Wang, Cai-Jin Lin, Yi-Fan Zhou, Tong Fu, Wen-Tao Yang, Ming Li, Hong Lv, Siyuan Chen, Anita Grigoriadis, Yi-Zhou Jiang, Ding Ma, Zhi-Ming Shao
Journal: Cancer Research
Cancer Res (2024) 84 (21): 3669–3683.
https://doi.org/10.1158/0008-5472.CAN-23-4066
Published: 04 November 2024
View articletitled, Molecular Characterization and Classification of HER2-Positive Breast Cancer Inform Tailored Therapeutic Strategies
Open the PDF for Molecular Characterization and Classification of HER2-Positive Breast Cancer Inform Tailored Therapeutic Strategies in another window
Includes: Supplementary data
Journal Articles

Abstract PO1-29-03: Efficacy, Safety, and Immunogenicity of TQ-B211 (a Trastuzumab Biosimilar) Plus Docetaxel versus Herceptin® Plus Docetaxel for HER2-positive Metastatic Breast Cancer: a Double-blind, Randomised, Multicenter, Phase 3 Trial

Xichun Hu, Qingyuan Zhang, Shusen Wang, Tao Sun, Xiaohua Zeng, Weimin Xie, Zhongsheng Tong, Hui Cao, Huihua Xiong, Xiuwen Wang, Jin Yang, Shuqun Zhang, Ying Wang, Chunhong Hu, Kaijian Lei, Binlin Ma, Wei Liu, Zhiyong Yu, PeiJian Peng, Hongwei Yang, Zhijun Yuan, Xiaojia Wang, Xujuan Wang, Hong Wang, Yongqian Shu, Nanlin Li, Wenbin Yue, Jingfen Wang, Daqing Wang, Zhiguo Luo, Junyang Mo, Yarong Li, Lili Sheng
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-29-03.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-29-03
Published: 02 May 2024
View articletitled, Abstract PO1-29-03: Efficacy, Safety, and Immunogenicity of TQ-B211 (a Trastuzumab Biosimilar) Plus Docetaxel versus Herceptin® Plus Docetaxel for HER2-positive Metastatic Breast Cancer: a Double-blind, Randomised, Multicenter, Phase 3 Trial
Journal Articles

Abstract PS08-08: Updated efficacy and safety of SKB264 (MK-2870) for previously treated metastatic triple negative breast cancer (mTNBC) in Phase 2 study

Yongmei Yin, Xinhong Wu, Quchang Ouyang, Min Yan, Lihua Song, YunPeng Liu, Zhongsheng Tong, Cuizhi Geng, Ying Wang, Guohua Yu, Xiang Wang, Ying Cheng, Weihong Zhao, Xiaoping Jin, Yina Diao, Gesha Liu, Mengyu Yang, Yue Yang, Yalan Yang, Lian Lu, Junyou Ge, Jin Li, Qun Li
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS08-08.
https://doi.org/10.1158/1538-7445.SABCS23-PS08-08
Published: 02 May 2024
View articletitled, Abstract PS08-08: Updated efficacy and safety of SKB264 (MK-2870) for previously treated metastatic triple negative breast cancer (mTNBC) in Phase 2 study
Journal Articles

Abstract PS17-08: A Phase Ib Study to Evaluate the Efficacy and Safety of Afuresertib Plus Fulvestrant in Patients with Locally Advanced or Metastatic HR+/HER2- Breast Cancer Who Failed Standard of Care Therapies

Binghe Xu, Pin Zhang, Tao Sun, Ying Wang, Zhongsheng Tong, Sneha Phadke, Trevor Feinstein, Pengfei Guo, Jing Qu, Xiaoyu Wang
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS17-08.
https://doi.org/10.1158/1538-7445.SABCS23-PS17-08
Published: 02 May 2024
View articletitled, Abstract PS17-08: A Phase Ib Study to Evaluate the Efficacy and Safety of Afuresertib Plus Fulvestrant in Patients with Locally Advanced or Metastatic HR+/HER2- Breast Cancer Who Failed Standard of Care Therapies
Journal Articles

Abstract PS09-09: Multiomics profiling and molecular classification refine precision treatment strategies for HER2-positive breast cancer

Yu-Wei Li, Ding Ma, Xiang-Rong Wu, Lei-Jie Dai, Shen Zhao, Yu-Zheng Xu, Xi Jin, Xiao Yi, Ying Wang, Cai-Jin Lin, Yi-Fan Zhou, Tong Fu, Wen-Tao Yang, Ming Li, Hong Lv, Yi-Zhou Jiang, Zhi-Ming Shao
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS09-09.
https://doi.org/10.1158/1538-7445.SABCS23-PS09-09
Published: 02 May 2024
View articletitled, Abstract PS09-09: Multiomics profiling and molecular classification refine precision treatment strategies for HER2-positive breast cancer
Journal Articles

Abstract CT128: Phase I/II clinical trials of LAE005, afuresertib plus nab-paclitaxel in patients with advanced solid tumors, primarily in patients with triple-negative breast cancer (TNBC)

Binghe Xu, Pin Zhang, Ying Wang, Zhongsheng Tong, Tingjing Yao, Xian Wang, Zijia Wang, Pengfei Guo, Wenyue Ma, Yong YUE
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT128.
https://doi.org/10.1158/1538-7445.AM2024-CT128
Published: 05 April 2024
View articletitled, Abstract CT128: Phase I/II clinical trials of LAE005, afuresertib plus nab-paclitaxel in patients with advanced solid tumors, primarily in patients with triple-negative breast cancer (TNBC)
Journal Articles

Abstract 6660: The novel codon-modified Zika virus CDX-602 shows anti-tumor efficacy and remodels the tumor microenvironment in preclinical models

Nusrat Jahan, Yiwen Zhao, Katarina Blagovic, Ying Wang, J Robert Coleman, Steffen Mueller, Johanna K. Kaufmann
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6660.
https://doi.org/10.1158/1538-7445.AM2024-6660
Published: 22 March 2024
View articletitled, Abstract 6660: The novel codon-modified Zika virus CDX-602 shows anti-tumor efficacy and remodels the tumor microenvironment in preclinical models
Journal Articles

Abstract 1834: Discovery of a novel and highly selective PARP7 inhibitor for cancer immunotherapy

Xiaohui Liu, Ying Wang, Dongliang Xia, Wei Zhang, Shijie Tian, Yan He, Xuerong Feng, Xia Yang, Qi Zhang, Shiyi Jiang, Meifeng Wu, Jianfeng Deng, Yeye Wang, Yuxi Su, Min Yao, Weijiao Yuan, Xuedan You
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1834.
https://doi.org/10.1158/1538-7445.AM2024-1834
Published: 22 March 2024
View articletitled, Abstract 1834: Discovery of a novel and highly selective PARP7 inhibitor for cancer immunotherapy
Journal Articles

Abstract 281: The function of FGFR2+ cancer-associated fibroblasts on cancer stem cell expansion of esophageal squamous cell carcinoma

Ying Wang, Ping Feng, Tong-chao Jiang, Xin-yuan Guan, Yun-fei Xia
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 281.
https://doi.org/10.1158/1538-7445.AM2024-281
Published: 22 March 2024
View articletitled, Abstract 281: The function of FGFR2+ cancer-associated fibroblasts on cancer stem cell expansion of esophageal squamous cell carcinoma
Journal Articles

Abstract 936: Targeted proteomics and next-generation sequencing (NGS) for biomarker discovery in metastatic colorectal cancer (mCRC)

William J. Kelly, Barrett Nuttall, Marlon Rebelatto, Marcus Schick, Armin Meier, Steve Sweet, Beom-Jun Kim, David Chain, Yeoun Jin Kim, Zhongwu Lai, Ying Wang, Todd H. Creasy, Ramya Gurrapu, Sakshi Gulati, Alice Barkell, Brian Dougherty, Danielle Carroll, Fabiola Cecchi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 936.
https://doi.org/10.1158/1538-7445.AM2024-936
Published: 22 March 2024
View articletitled, Abstract 936: Targeted proteomics and next-generation sequencing (NGS) for biomarker discovery in metastatic colorectal cancer (mCRC)