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Journal Articles

Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion

Open Access
Tianhao Zhang, Ying Li, Ertao Zhai, Risheng Zhao, Yan Qian, Zhixin Huang, Yinan Liu, Zeyu Zhao, Xiang Xu, Jianqiu Liu, Zikang Li, Zhi Liang, Ran Wei, Linying Ye, Jinping Ma, Qingping Wu, Jianhui Chen, Shirong Cai
Journal: Cancer Research
Cancer Res (2025) 85 (10): 1819–1841.
https://doi.org/10.1158/0008-5472.CAN-24-2580
Published: 15 May 2025
View articletitled, Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion
Open the PDF for Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion in another window
Includes: Supplementary data
Journal Articles

Abstract CT144: Phase I investigator-initiated clinical trial of CD19CAR -T cells secreting PD-1-targeted IL-21 in relapsed/refractory B-cell non-Hodgkin lymphoma

Free
Yu Jing, Ying Li, Meng Li, Shengjuan Zhang, Baocai Zhao, Yueyi An, Hang Li, Jitao Zhao, Liping Dou, Shengdian Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT144.
https://doi.org/10.1158/1538-7445.AM2025-CT144
Published: 25 April 2025
View articletitled, Abstract CT144: Phase I investigator-initiated clinical trial of CD19CAR -T cells secreting PD-1-targeted IL-21 in relapsed/refractory B-cell non-Hodgkin lymphoma
Journal Articles

Abstract CT145: Phase I investigator-initiated clinical trial of BCMACAR -T cells secreting PD-1-targeted IL-21 in relapsed/refractory multiple myeloma

Free
Meng Li, Ying Li, Yu Jing, Shengjuan Zhang, Baocai Zhao, Yueyi An, Hang Li, Liping Dou, Shengdian Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT145.
https://doi.org/10.1158/1538-7445.AM2025-CT145
Published: 25 April 2025
View articletitled, Abstract CT145: Phase I investigator-initiated clinical trial of BCMACAR -T cells secreting PD-1-targeted IL-21 in relapsed/refractory multiple myeloma
Journal Articles

Abstract 6735: E-cM-Topi, a potent EGFR-cMET bispecific antibody drug conjugate, with superior anti-tumor effect in non-small-cell lung cancer (NSCLC)

Free
Huihui Chen, Le Sun, Bing Hu, Zhiping Zhao, Ziheng Liu, Guangbao Qiu, Dongmei Bai, Ying Li, Ziwei Ren, Ting Zhang, Xin Ye, Lingfeng You, Zhendong Xue, Yuchang Mao, Huaixin Dang, Shuyu Cai, Jun Feng, Min Hu, Feng He
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6735.
https://doi.org/10.1158/1538-7445.AM2025-6735
Published: 21 April 2025
View articletitled, Abstract 6735: E-cM-Topi, a potent EGFR-cMET bispecific antibody drug conjugate, with superior anti-tumor effect in non-small-cell lung cancer (NSCLC)
Journal Articles

Abstract 2444: A deep learning framework for the reconstruction of gene expression profiles derived from formalin-fixed paraffin-embedded samples

Free
Lingli He, Kai Song, Ying Li, Celia Yujuan Dong, Cherry Y. Wong, Lin Qi, Xianrui Zhang, Yufeng Chen, Louis Vermeulen, Shentao Zhou, Simon Siu Ng, Xin Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2444.
https://doi.org/10.1158/1538-7445.AM2025-2444
Published: 21 April 2025
View articletitled, Abstract 2444: A deep learning framework for the reconstruction of gene expression profiles derived from formalin-fixed paraffin-embedded samples
Journal Articles

Abstract 3426: Preclinical development of CD-001, a novel fusion protein combining PD-1 blockade with IL-21 for solid tumors

Free
Ying Li, Xiao Luan, Shaonan Zhou, Xiangrui Cheng, Jitao Zhao, Guoju Sang, Hao Shen, Naibo Yang, Junjie Yang, Jian Xu, Shengdian Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3426.
https://doi.org/10.1158/1538-7445.AM2025-3426
Published: 21 April 2025
View articletitled, Abstract 3426: Preclinical development of CD-001, a novel fusion protein combining PD-1 blockade with IL-21 for solid tumors
Journal Articles

Abstract 5453: E-M ADC, a promising EGFR-MUC1 bispecific antibody drug conjugate, with superior anti-tumor effect in a wide range of tumors

Free
Ziheng Liu, Le Sun, Bing Hu, Lingfeng You, Xinyu Gao, Jin Shao, Shimeng Liu, Beibei Fu, Ying Li, Manting Zhang, Dandan Xiong, Yan Liu, Guangbao Qiu, Ziwei Ren, Zhendong Xue, Yuchang Mao, Huaixin Dang, Ting Zhang, Xin Ye, Shuyu Cai, Jun Feng, Min Hu, Feng He
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5453.
https://doi.org/10.1158/1538-7445.AM2025-5453
Published: 21 April 2025
View articletitled, Abstract 5453: E-M ADC, a promising EGFR-MUC1 bispecific antibody drug conjugate, with superior anti-tumor effect in a wide range of tumors
Journal Articles

Abstract CT180: Phase I clinical trial of CD19CAR -T cells secreting PD-1-targeting IL-21 in advanced relapsed/refractory acute lymphoblastic leukemia

Free
Yu Jing, Ying Li, Liping Dou, Shengjuan Zhang, Ran Tian, Guojing Wang, Xiangrui Cheng, Jitao Zhao, Hang Li, Yueyi An, Naibo Yang, Shengdian Wang
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT180.
https://doi.org/10.1158/1538-7445.AM2024-CT180
Published: 05 April 2024
View articletitled, Abstract CT180: Phase I clinical trial of CD19CAR -T cells secreting PD-1-targeting IL-21 in advanced relapsed/refractory acute lymphoblastic leukemia
Journal Articles

Abstract 152: Exploring the impact of heat shock protein 90 on the antitumor efficacy and stemness in medulloblastoma cells

Free
Shu-Mei Chen, Hsieng-Yun Huang, Chien-Kai Wang, Yi-Yuan Yang, Sy-Jye Leu, Ying-Ying Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 152.
https://doi.org/10.1158/1538-7445.AM2024-152
Published: 22 March 2024
View articletitled, Abstract 152: Exploring the impact of heat shock protein 90 on the antitumor efficacy and stemness in medulloblastoma cells
Journal Articles

Abstract 2664: Targeting PD-L1/CMTM6 in myeloid cells results in elevated release of CCL2 to improve CD8 T cell-mediated antitumor response

Free
Michelle Alexandria Hsu, Xin Liu, Ying Li, Whitney Barham, Kevin Pavelko, Jake Hirdler, Fabrice Lucien, Haidong Dong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2664.
https://doi.org/10.1158/1538-7445.AM2024-2664
Published: 22 March 2024
View articletitled, Abstract 2664: Targeting PD-L1/CMTM6 in myeloid cells results in elevated release of CCL2 to improve CD8 T cell-mediated antitumor response
Journal Articles

Abstract 4001: Monocyte transcriptome profiles associated with clinical response in patients with B-cell non-Hodgkin’s lymphoma receiving CD19-directed CAR-T therapy

Free
Andre de Menezes Silva Corraes, Panwen Wang, Radhika Bansal, Henan Zhang, Zuoyi Shao, Kevin Regan, Eider Moreno Cortes, Arushi Khurana, Nora Bennani, Yucai Wang, Paul Hampel, Jonas Paludo, Patrick Johnston, Hemant Murthy, Madiha Iqbal, Stephen Ansell, Javier Munoz, Allison Rosenthal, Mohamed Kharfan-Dabaja, Januario Castro, Saad Kenderian, Haidong Dong, Ying Li, Yi Lin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4001.
https://doi.org/10.1158/1538-7445.AM2024-4001
Published: 22 March 2024
View articletitled, Abstract 4001: Monocyte transcriptome profiles associated with clinical response in patients with B-cell non-Hodgkin’s lymphoma receiving CD19-directed CAR-T therapy
Journal Articles

Abstract 4967: Predicting progression-free survival (PFS) in first-line (1L) immune checkpoint inhibitor (ICI)-treated patients (pts) with advanced non-small cell lung cancer (aNSCLC): Machine learning (ML) application in real-world data

Free
Deep K. Hathi, James Harnett, Ning Wu, Zhenxing Xu, Weishen Pan, T G. Hager, Ruben G. Quek, Shivani Aggarwal, Young Kim, Petra Rietschel, Frank Seebach, Fei Wang, Ying Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4967.
https://doi.org/10.1158/1538-7445.AM2024-4967
Published: 22 March 2024
View articletitled, Abstract 4967: Predicting progression-free survival (PFS) in first-line (1L) immune checkpoint inhibitor (ICI)-treated patients (pts) with advanced non-small cell lung cancer (aNSCLC): Machine learning (ML) application in real-world data
Journal Articles

Abstract 3840: Can serum exosomal content predict response to immunotherapy in hepatocellular carcinoma

Free
Niramol Savaraj, Pablo Puente, Ying-Ying Li, Chunjing Wu, Jonathan D. Nguyen, Medhi Wangpaichitr, Peter J. Hosein, Lynn G. Feun
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3840.
https://doi.org/10.1158/1538-7445.AM2024-3840
Published: 22 March 2024
View articletitled, Abstract 3840: Can serum exosomal content predict response to immunotherapy in hepatocellular carcinoma
Journal Articles

Abstract 4404: EZH2 modulates mRNA splicing in chronic myeloid leukemia through the repression of splicing factors and exerts part of its oncogenic function through the regulation of CELF2

Free
Reinhard Brunmeir, Ying Li, Baohong Lin, Leong Qiao Zheng, Henry Yang, Wee Joo Chng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4404.
https://doi.org/10.1158/1538-7445.AM2024-4404
Published: 22 March 2024
View articletitled, Abstract 4404: EZH2 modulates mRNA splicing in chronic myeloid leukemia through the repression of splicing factors and exerts part of its oncogenic function through the regulation of CELF2
Journal Articles

Abstract 53: T-cell receptor repertoire changes associated with clinical response in patients with B-cell non-Hodgkin’s lymphoma receiving CD19 CAR-T therapy

Free
Aiman J. Faruqi, Panwen Wang, Radhika Bansal, Andre De Menezes Silva Corraes, Henan Zhang, Zuoyi Shao, Kevin Regan, Eider Moreno Cortes, Arushi Khurana, Nora Bennani, Yucai Wang, Paul Hampel, Jonas Paludo, Patrick Johnston, Hemant Murthy, Madiha Iqbal, Stephen Ansell, Javier Munoz, Allison Rosenthal, Mohamed Kharfan Dabaja, Januario E. Castro, Saad Kenderian, Haidong Dong, Ying Li, Yi Lin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 53.
https://doi.org/10.1158/1538-7445.AM2024-53
Published: 22 March 2024
View articletitled, Abstract 53: T-cell receptor repertoire changes associated with clinical response in patients with B-cell non-Hodgkin’s lymphoma receiving CD19 CAR-T therapy
Journal Articles

Abstract 4959: Immunopipe: A comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline

Free
Panwen Wang, Haidong Dong, Yue Yu, Shuwen Zhang, Zhifu Sun, Jean-Pierre A. Kocher, Junwen Wang, Lin Yi, Ying Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4959.
https://doi.org/10.1158/1538-7445.AM2024-4959
Published: 22 March 2024
View articletitled, Abstract 4959: Immunopipe: A comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline
Journal Articles

Abstract 3999: Augmentation of antitumor effects by CAR-T cells secreting anti-PD-1 single-chain antibody fused with IL-21

Free
Ying Li, Jitao Zhao, Xiangrui Cheng, Hang Li, Ran Tian, Qianqian He, Shengdian Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3999.
https://doi.org/10.1158/1538-7445.AM2024-3999
Published: 22 March 2024
View articletitled, Abstract 3999: Augmentation of antitumor effects by CAR-T cells secreting anti-PD-1 single-chain antibody fused with IL-21
Journal Articles

Abstract 5201: TNFR2 humanized mice: an ideal model for studying anti-TNFR2 antibodies

Free
Huiyi Wang, Ying Li, Mingkun Zhang, Xu Su, Santi Suryani Chen, Zhiying Li, Mark Wade Moore, Jing Zhao, Xiang Gao, Cunxiang Ju
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5201.
https://doi.org/10.1158/1538-7445.AM2023-5201
Published: 04 April 2023
View articletitled, Abstract 5201: TNFR2 humanized mice: an ideal model for studying anti-TNFR2 antibodies
Journal Articles

Abstract 577: ENPP1 inhibitor ZX-8177 in combination with chemotherapy or radiation exhibits synergistic anti-tumor effects via STING-mediated response

Free
Xiaoli Qin, Ying-ying Li, Shuaijun Sun, Xiaomin Li, Zhiyuan Peng, Deming Kong, Siyu Shui, Jinfu Yang, Xiaolin Alan Hao
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 577.
https://doi.org/10.1158/1538-7445.AM2023-577
Published: 04 April 2023
View articletitled, Abstract 577: ENPP1 inhibitor ZX-8177 in combination with chemotherapy or radiation exhibits synergistic anti-tumor effects via STING-mediated response
Journal Articles

Abstract 5054: The study of synergy mechanism between surufatinib and vinorelbine in the treatment of non-small cell lung cancer

Free
Xiaoran Wu, Yanfang Zheng, Lingyu Qin, Ying Li, Zhongjian Yu, Xiongjie Zhu, Rui Cai, Feiyu Niu, Yan Yuan, Peng Jiang, Shaoshi Wen, Xing Lv, Jiancai Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5054.
https://doi.org/10.1158/1538-7445.AM2023-5054
Published: 04 April 2023
View articletitled, Abstract 5054: The study of synergy mechanism between surufatinib and vinorelbine in the treatment of non-small cell lung cancer