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Journal Articles

Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis

Min Fu, Qian Gao, Mian Xiao, Rui-Feng Li, Xin-Yi Sun, Sheng-Lin Li, Xin Peng, Xi-Yuan Ge
Journal: Cancer Research
Cancer Res (2024) 84 (15): 2484–2500.
https://doi.org/10.1158/0008-5472.CAN-23-3508
Published: 01 August 2024
View article titled, Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis
Open the PDF for Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 4391: The UBE2F-CRL5Asb11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells

Yi Sun, Yu Chang, Qian Che, Hua Li, Jie Xu, Mingjia Tan, Xiufang Xiong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4391.
https://doi.org/10.1158/1538-7445.AM2024-4391
Published: 22 March 2024
View article titled, Abstract 4391: The UBE2F-CRL5<sup>Asb11</sup>-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
Journal Articles

Abstract 4003: TBK1 inhibition enhances CAR-T cell efficacy against patient-derived organotypic tumor spheroids

Luke Maggs, Yi Sun, Giulia Cattaneo, Marco Ventin, Feng Chen, Martin Q. Rasmussen, Xinhui Wang, Cristina R. Ferrone, Soldano Ferrone, Russell W. Jenkins
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4003.
https://doi.org/10.1158/1538-7445.AM2024-4003
Published: 22 March 2024
View article titled, Abstract 4003: TBK1 inhibition enhances CAR-T cell efficacy against patient-derived organotypic tumor spheroids
Journal Articles

Abstract 3285: Targeting TBK1 to overcome resistance to cancer immunotherapy

Yi Sun, Or-Yam Revach, Seth Anderson, Anne Jenney, Caitlin E. Mills, Payal Tiwari, Robert T. Manguso, Russell William Jenkins
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3285.
https://doi.org/10.1158/1538-7445.AM2023-3285
Published: 04 April 2023
View article titled, Abstract 3285: Targeting TBK1 to overcome resistance to cancer immunotherapy
Journal Articles

Abstract 4072: Class I HLA-independent lysis of immunotherapy-resistant melanoma by CD8 T cells

Hongyan Xie, Aiping Jiang, Anne Jenney, Yi Sun, Tatyana Sharova, Moshe Sade-Feldman, Or-yam Revach, Angelina Cicerchia, Martin Q. Rasmussen, Nir Hacohen, Robert T. Manguso, Russell W. Jenkins
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4072.
https://doi.org/10.1158/1538-7445.AM2023-4072
Published: 04 April 2023
View article titled, Abstract 4072: Class I HLA-independent lysis of immunotherapy-resistant melanoma by CD8 T cells
Journal Articles

Abstract OT2-22-01: Epirubicin, cyclophosphamide and pyrotinib followed by docetaxel, trastuzumab and pyrotinib as neoadjuvant therapy for stage II-III HER2-positive breast cancer: a single-arm, multicenter phase 2 trial

Qiyun Shi, Xiaowei Qi, Peng Tang, Linjun Fan, Li Chen, Shushu Wang, Guozhi Zhang, Mengyuan Wang, Hongying Che, Pengwei Lv, Dejie Chen, Jinhui Hu, Qiuyun Li, Yanwu Zhang, Qiao Yu, Kunxian Yang, Yuan Zhong, Chuang Chen, Zemin Zhou, Liyuan Qian, Jingwei Zhang, Mingde Ma, Yi Sun, Jiangbo Liu, Yi Zhang, Jun Jiang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT2-22-01.
https://doi.org/10.1158/1538-7445.SABCS22-OT2-22-01
Published: 01 March 2023
View article titled, Abstract OT2-22-01: Epirubicin, cyclophosphamide and pyrotinib followed by docetaxel, trastuzumab and pyrotinib as neoadjuvant therapy for stage II-III HER2-positive breast cancer: a single-arm, multicenter phase 2 trial
Journal Articles

An Alternatively Spliced p62 Isoform Confers Resistance to Chemotherapy in Breast Cancer

Qianying Guo, Hao Wang, Jiahao Duan, Wenwu Luo, Rongrong Zhao, Yuting Shen, Bijun Wang, Siqi Tao, Yi Sun, Qian Ye, Xiaomin Bi, Hui Yuan, Qiang Wu, Peter E. Lobie, Tao Zhu, Sheng Tan, Xing Huang, Zhengsheng Wu
Journal: Cancer Research
Cancer Res (2022) 82 (21): 4001–4015.
https://doi.org/10.1158/0008-5472.CAN-22-0909
Published: 02 November 2022
View article titled, An Alternatively Spliced p62 Isoform Confers Resistance to Chemotherapy in Breast Cancer
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Includes: Supplementary data
Journal Articles

Label-Free Deep Profiling of the Tumor Microenvironment

Sixian You, Eric J. Chaney, Haohua Tu, Yi Sun, Saurabh Sinha, Stephen A. Boppart
Journal: Cancer Research
Cancer Res (2021) 81 (9): 2534–2544.
https://doi.org/10.1158/0008-5472.CAN-20-3124
Published: 01 May 2021
View article titled, Label-Free Deep Profiling of the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

Pomalidomide Inhibits PD-L1 Induction to Promote Antitumor Immunity

Yuki Fujiwara, Yi Sun, Robert J. Torphy, Jiadai He, Katsuhiko Yanaga, Barish H. Edil, Richard D. Schulick, Yuwen Zhu
Journal: Cancer Research
Cancer Res (2018) 78 (23): 6655–6665.
https://doi.org/10.1158/0008-5472.CAN-18-1781
Published: 03 December 2018
View article titled, Pomalidomide Inhibits PD-L1 Induction to Promote Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Abstract 3044: Label-free detection and identification of cancer-associated vesicles in human breast cancer

Sixian You, Yi Sun, Haohua Tu, Ronit Barkalifa, Eric J. Chaney, Marina Marjanovic, Anna M. Higham, Natasha N. Luckey, Kimberly A. Cradock, Z. George Liu, Stephen A. Boppart
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3044.
https://doi.org/10.1158/1538-7445.AM2018-3044
Published: 01 July 2018
View article titled, Abstract 3044: Label-free detection and identification of cancer-associated vesicles in human breast cancer
Journal Articles

Abstract 4012: SAG/RBX2/ROC2 regulates pancreatic cancer initiation, cystic formation in mice driven by KrasG12D

Mingjia Tan, Qiang Zhang, Yi Sun
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4012.
https://doi.org/10.1158/1538-7445.AM2018-4012
Published: 01 July 2018
View article titled, Abstract 4012: SAG/RBX2/ROC2 regulates pancreatic cancer initiation, cystic formation in mice driven by Kras<sup>G12D</sup>
Journal Articles

Abstract B76: Targeting Mcl-1 for radiosensitization of pancreatic cancers

Qiang Zhang, Dongping Wei, Jason Schreiber, Tasneem Kausar, Theodore Lawrence, Yi Sun, Zaneta Nikolovska-Coleska, Meredith A. Morgan
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B76.
https://doi.org/10.1158/1538-7445.PANCA2014-B76
Published: 30 June 2015
View article titled, Abstract B76: Targeting Mcl-1 for radiosensitization of pancreatic cancers
Journal Articles

Abstract 4436: Neddylation of ribosomal protein S27-like and RPS27 regulates survival of breast cancer cells

Yongchao Zhao, Xiufang Xiong, Yi Sun
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4436.
https://doi.org/10.1158/1538-7445.AM2014-4436
Published: 01 October 2014
View article titled, Abstract 4436: Neddylation of ribosomal protein S27-like and RPS27 regulates survival of breast cancer cells
Journal Articles

Abstract 1582: Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancer cells by modulation of CDC25C.

Dongping Wei, Leslie A. Parsels, Mary A. Davis, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Yi Sun, Meredith A. Morgan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1582.
https://doi.org/10.1158/1538-7445.AM2013-1582
Published: 15 April 2013
View article titled, Abstract 1582: Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancer cells by modulation of CDC25C.
Journal Articles

Abstract 1657: Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis in breast cancer cells.

Yongchao Zhao, Xiufang Xiong, Lijun Jia, Yi Sun
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1657.
https://doi.org/10.1158/1538-7445.AM2013-1657
Published: 15 April 2013
View article titled, Abstract 1657: Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis in breast cancer cells.
Journal Articles

The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth

Zhongguang Luo, Guangyang Yu, Hyuk Woo Lee, Lihui Li, Lingyan Wang, Dongqin Yang, Yongfu Pan, Chan Ding, Jing Qian, Lijun Wu, Yiwei Chu, Jing Yi, Xiangdong Wang, Yi Sun, Lak Shin Jeong, Jie Liu, Lijun Jia
Journal: Cancer Research
Cancer Res (2012) 72 (13): 3360–3371.
https://doi.org/10.1158/0008-5472.CAN-12-0388
Published: 01 July 2012
View article titled, The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth
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Includes: Supplementary data
Journal Articles

Abstract 4160: DEPTOR, an mTOR inhibitor, is a novel substrate of SCFαTrCP E3 ubiquitin ligase upon S6K1/RSK1 phosphorylation and regulates survival and autophagy

Yongchao Zhao, Xiufang Xiong, Yi Sun
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4160.
https://doi.org/10.1158/1538-7445.AM2012-4160
Published: 15 April 2012
View article titled, Abstract 4160: DEPTOR, an mTOR inhibitor, is a novel substrate of SCFαTrCP E3 ubiquitin ligase upon S6K1/RSK1 phosphorylation and regulates survival and autophagy
Journal Articles

Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor

Dongping Wei, Hua Li, Jie Yu, Jonathan T. Sebolt, Lili Zhao, Theodore S. Lawrence, Peter G. Smith, Meredith A. Morgan, Yi Sun
Journal: Cancer Research
Cancer Res (2012) 72 (1): 282–293.
https://doi.org/10.1158/0008-5472.CAN-11-2866
Published: 02 January 2012
View article titled, Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor
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Includes: Supplementary data
Journal Articles

Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition

Zhen Wang, Min Zheng, Zhichuan Li, Ruiguo Li, Lijun Jia, Xiufang Xiong, Noel Southall, Shaomeng Wang, Menghang Xia, Christopher P. Austin, Wei Zheng, Zijian Xie, Yi Sun
Journal: Cancer Research
Cancer Res (2009) 69 (16): 6556–6564.
https://doi.org/10.1158/0008-5472.CAN-09-0891
Published: 12 August 2009
View article titled, Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
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Includes: Supplementary data
Journal Articles

ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G2-M Arrest, Apoptosis, and Senescence

Lijun Jia, Maria S. Soengas, Yi Sun
Journal: Cancer Research
Cancer Res (2009) 69 (12): 4974–4982.
https://doi.org/10.1158/0008-5472.CAN-08-4671
Published: 15 June 2009
View article titled, ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G<sub>2</sub>-M Arrest, Apoptosis, and Senescence
Open the PDF for ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G<sub>2</sub>-M Arrest, Apoptosis, and Senescence in another window
Includes: Supplementary data