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Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification

Cancer Res (2025)

https://doi.org/10.1158/0008-5472.CAN-24-4251

Published: 30 April 2025

View articletitled, Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification

Includes: Supplementary data

Journal Articles

Abstract 4915: A multi-protein score to predict hepatocellular carcinoma occurrence

Eleanor Watts, Steven Moore, Belynda Hicks, Wen-Yi Huang, Erikka Loftfield, Mitchell Machiela, Katherine McGlynn, Jianxin Shi, Rachael Stolzenberg-Solomon, Cody Watling

Cancer Res (2025) 85 (8_Supplement_1): 4915.

https://doi.org/10.1158/1538-7445.AM2025-4915

Published: 21 April 2025

View articletitled, Abstract 4915: A multi-protein score to predict hepatocellular carcinoma occurrence

Journal Articles

Abstract 3735: A prospective study of excess weight and weight change in adulthood and risk of colorectal cancer incidence and mortality

Wen-Yi Huang, Steven C. Moore, Kathryn Hughes Barry, Sonja I. Berndt

Cancer Res (2025) 85 (8_Supplement_1): 3735.

https://doi.org/10.1158/1538-7445.AM2025-3735

Published: 21 April 2025

View articletitled, Abstract 3735: A prospective study of excess weight and weight change in adulthood and risk of colorectal cancer incidence and mortality

Journal Articles

Abstract 4096: Altered epigenetic aging in leukocytes with detectable mosaic chromosomal alterations

Corey D. Young, Derek W. Brown, Charles Breeze, Rebecca L. Kelly, Kara M. Barnao, Aubrey K. Hubbard, Weiyin Zhou, Amy A. Hutchinson, Belynda D. Hicks, Aurélie L. Vogt, Wen-Yi Huang, Steven C. Moore, Stephen J. Chanock, Mitchell J. Machiela

Cancer Res (2025) 85 (8_Supplement_1): 4096.

https://doi.org/10.1158/1538-7445.AM2025-4096

Published: 21 April 2025

View articletitled, Abstract 4096: Altered epigenetic aging in leukocytes with detectable mosaic chromosomal alterations

Journal Articles

Abstract 1197: Association of increasing alcohol intake over the lifetime with colorectal adenoma and colorectal cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

Caitlin P. O'Connell, Sonja I. Berndt, Kenechukwu Chudy-Onwugaje, Andrew T. Kunzmann, Wen-Yi Huang, Kathryn Hughes Barry, Erikka Loftfield

Cancer Res (2025) 85 (8_Supplement_1): 1197.

https://doi.org/10.1158/1538-7445.AM2025-1197

Published: 21 April 2025

View articletitled, Abstract 1197: Association of increasing alcohol intake over the lifetime with colorectal adenoma and colorectal cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

Journal Articles

Abstract 1799: Harnessing the GlycOBI® enabling technologies: next-generation site-specific glycan ADCs with versatile DAR to enhance therapeutic index

Teng-Yi Huang, Ka-Shu Fung, Yu-Chao Huang, Chi-Sheng Shia, Chi-Huan Lu, Nan-Hsuan Wang, Ya-Chi Chen, Ming-Tain Lai

Cancer Res (2025) 85 (8_Supplement_1): 1799.

https://doi.org/10.1158/1538-7445.AM2025-1799

Published: 21 April 2025

View articletitled, Abstract 1799: Harnessing the GlycOBI® enabling technologies: next-generation site-specific glycan ADCs with versatile DAR to enhance therapeutic index

Journal Articles

Abstract 5675: ThiOBI® platform, a novel hydrophilic linker for irreversible cysteine-selective biomolecular conjugation, demonstrated potent and durable antitumor activities in various animal models

Yu-Chao Huang, Ting-Wei Liu, Chi-Huan Lu, Ren-Yu Hsu, Nan-Hsuan Wang, Ya-Chi Chen, Ming-Tain Lai, Teng-Yi Huang

Cancer Res (2025) 85 (8_Supplement_1): 5675.

https://doi.org/10.1158/1538-7445.AM2025-5675

Published: 21 April 2025

View articletitled, Abstract 5675: ThiOBI® platform, a novel hydrophilic linker for irreversible cysteine-selective biomolecular conjugation, demonstrated potent and durable antitumor activities in various animal models

Journal Articles

Abstract 3579: Racial disparity in microbial risk score for predicting subsequent risk of head and neck squamous cell cancer

Soyoung Kwak, Chan Wang, Mykhaylo Usyk, Feng Wu, Steve C. Moore, Wen-Yi Huang, Caroline Y. Um, Martha J. Shrubsole, Qiuyin Cai, Huilin Li, Jiyoung Ahn, Richard B. Hayes

Cancer Res (2025) 85 (8_Supplement_1): 3579.

https://doi.org/10.1158/1538-7445.AM2025-3579

Published: 21 April 2025

View articletitled, Abstract 3579: Racial disparity in microbial risk score for predicting subsequent risk of head and neck squamous cell cancer

Journal Articles

Abstract 840: Serum concentrations of per- and polyfluorinated substances and risk of non-Hodgkin lymphoma

Jongeun Rhee, Jani Koponen, Joshua N. Sampson, Alexander P. Keil, Mary H. Ward, Jonathan N. Hofmann, Wen-Yi Huang, Debra T. Silverman, Panu Rantakokko, Mark P. Purdue

Cancer Res (2024) 84 (6_Supplement): 840.

https://doi.org/10.1158/1538-7445.AM2024-840

Published: 22 March 2024

View articletitled, Abstract 840: Serum concentrations of per- and polyfluorinated substances and risk of non-Hodgkin lymphoma

Journal Articles

Abstract 6617: Oral microbiome and subsequent risk for head and neck squamous cell cancer development

Soyoung Kwak, Mykhaylo Usyk, Feng Wu, Neal D. Freedman, Wen-Yi Huang, Marji L. Mccullough, Caroline Y. Um, Martha J. Shrubsole, Qiuyin Cai, Chan Wang, Huilin Li, Jiyoung Ahn, Richard B. Hayes

Cancer Res (2024) 84 (6_Supplement): 6617.

https://doi.org/10.1158/1538-7445.AM2024-6617

Published: 22 March 2024

View articletitled, Abstract 6617: Oral microbiome and subsequent risk for head and neck squamous cell cancer development

Journal Articles

Abstract 3149: Development of a novel site-specific ADC glycan platform with potential for improved in vivo efficacy and stability of the ADC in animal studies

Teng-Yi Huang, Yin-Cheng Hsieh, Ka-Shu Fung, Yu-Chao Huang, Chi-Sheng Shia, Ming-Feng Chiang, Nan-Hsuan Wang, Wan-Fen Li, Ming-Tain Lai

Cancer Res (2024) 84 (6_Supplement): 3149.

https://doi.org/10.1158/1538-7445.AM2024-3149

Published: 22 March 2024

View articletitled, Abstract 3149: Development of a novel site-specific ADC glycan platform with potential for improved in vivo efficacy and stability of the ADC in animal studies

Journal Articles

Abstract 775: Underlying germline genetic architecture of pediatric sarcomas: Evaluating the role of common and rare variants in 4,160 patients

Cancer Res (2024) 84 (6_Supplement): 775.

https://doi.org/10.1158/1538-7445.AM2024-775

Published: 22 March 2024

View articletitled, Abstract 775: Underlying germline genetic architecture of pediatric sarcomas: Evaluating the role of common and rare variants in 4,160 patients

Journal Articles

Abstract 3430: Mosaic loss of the Y chromosome is associated with prostate cancer risk

Rebecca L. Kelly, Weiyin Zhou, Kara M. Barnao, Corey D. Young, Aubrey K. Hubbard, Sairah M. Khan, Wen-Yi Huang, Stephen J. Chanock, Mitchell J. Machiela

Cancer Res (2024) 84 (6_Supplement): 3430.

https://doi.org/10.1158/1538-7445.AM2024-3430

Published: 22 March 2024

View articletitled, Abstract 3430: Mosaic loss of the Y chromosome is associated with prostate cancer risk

Journal Articles

Abstract 6151: Relationship between polygenic risk score, lifestyle factors, and colorectal cancer risk

Wen-Yi Huang, Erikka Loftfield, Rebecca Landy, Difei Wang, Hormuzd A. Katki, Jianxin Shi, Lingxiao Wang, Mitchell J. Machiela, Neal D. Freedman, Sonja I. Berndt

Cancer Res (2024) 84 (6_Supplement): 6151.

https://doi.org/10.1158/1538-7445.AM2024-6151

Published: 22 March 2024

View articletitled, Abstract 6151: Relationship between polygenic risk score, lifestyle factors, and colorectal cancer risk

Journal Articles

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRAS^G12C Inhibitor Efficacy

Cancer Res (2023) 83 (24): 4095–4111.

https://doi.org/10.1158/0008-5472.CAN-23-2729

Published: 15 December 2023

View articletitled, Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

Includes: Supplementary data

Journal Articles

Abstract 1953: Association between genetic ancestry and all-cause mortality among Black and White ever-smokers in the PLCO cohort

Courtney D. Dill, Dontray Crump, Rebecca Landy, Li C. Cheung, Wen-Yi Huang, Sonja Berndt, Neal Freedman, Hormuzd Katki

Cancer Res (2023) 83 (7_Supplement): 1953.

https://doi.org/10.1158/1538-7445.AM2023-1953

Published: 04 April 2023

View articletitled, Abstract 1953: Association between genetic ancestry and all-cause mortality among Black and White ever-smokers in the PLCO cohort

Journal Articles

Abstract 6453: Lifestyle and environmental factors in relation to colorectal cancer risk and survival by colibactin tumor mutational signature status

Cancer Res (2023) 83 (7_Supplement): 6453.

https://doi.org/10.1158/1538-7445.AM2023-6453

Published: 04 April 2023

View articletitled, Abstract 6453: Lifestyle and environmental factors in relation to colorectal cancer risk and survival by colibactin tumor mutational signature status

Journal Articles

Abstract 5925: Prevalence of clonal hematopoiesis in patients with monoclonal gammopathy of undetermined significance

Vianey Quaney, Benjamin Kroger, Aishwarya Sannareddy, Umar Khan, Fatma Kalkan, Robert H. Collins, Yazan F. Madanat, Madhuri Vusirikala, Yi Huang, Farrukh T. Awan, Praveen Ramakrishnan, Aimaz Afrough, Larry D. Anderson, Stephen S. Chung, Gurbakhash Kaur

Cancer Res (2023) 83 (7_Supplement): 5925.

https://doi.org/10.1158/1538-7445.AM2023-5925

Published: 04 April 2023

View articletitled, Abstract 5925: Prevalence of clonal hematopoiesis in patients with monoclonal gammopathy of undetermined significance

Journal Articles

Abstract 129: Determine the genetic similarity of synchronous endometrial and ovarian cancers with variants in polyguanine sequences

Yu-Yi Huang, Pei-Chi Cheng, Ching Hsu, Yung-Ming Jeng, Lin-Hung Wei, Wei-Ting Hung

Cancer Res (2023) 83 (7_Supplement): 129.

https://doi.org/10.1158/1538-7445.AM2023-129

Published: 04 April 2023

View articletitled, Abstract 129: Determine the genetic similarity of synchronous endometrial and ovarian cancers with variants in polyguanine sequences

Journal Articles

Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy

Naoshad Muhammad, Fiona Ruiz, Jennifer Stanley, Ramachandran Rashmi, Kevin Cho, Kay Jayachandran, Michael C. Zahner, Yi Huang, Jin Zhang, Stephanie Markovina, Gary J. Patti, Julie K. Schwarz

Cancer Res (2022) 82 (24): 4515–4527.

https://doi.org/10.1158/0008-5472.CAN-21-4369

Published: 16 December 2022

View articletitled, Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy

Includes: Supplementary data

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Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification

Abstract 4915: A multi-protein score to predict hepatocellular carcinoma occurrence

Abstract 3735: A prospective study of excess weight and weight change in adulthood and risk of colorectal cancer incidence and mortality

Abstract 4096: Altered epigenetic aging in leukocytes with detectable mosaic chromosomal alterations

Abstract 1197: Association of increasing alcohol intake over the lifetime with colorectal adenoma and colorectal cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

Abstract 1799: Harnessing the GlycOBI® enabling technologies: next-generation site-specific glycan ADCs with versatile DAR to enhance therapeutic index

Abstract 5675: ThiOBI® platform, a novel hydrophilic linker for irreversible cysteine-selective biomolecular conjugation, demonstrated potent and durable antitumor activities in various animal models

Abstract 3579: Racial disparity in microbial risk score for predicting subsequent risk of head and neck squamous cell cancer

Abstract 840: Serum concentrations of per- and polyfluorinated substances and risk of non-Hodgkin lymphoma

Abstract 6617: Oral microbiome and subsequent risk for head and neck squamous cell cancer development

Abstract 3149: Development of a novel site-specific ADC glycan platform with potential for improved in vivo efficacy and stability of the ADC in animal studies

Abstract 775: Underlying germline genetic architecture of pediatric sarcomas: Evaluating the role of common and rare variants in 4,160 patients

Abstract 3430: Mosaic loss of the Y chromosome is associated with prostate cancer risk

Abstract 6151: Relationship between polygenic risk score, lifestyle factors, and colorectal cancer risk

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRAS^G12C Inhibitor Efficacy

Abstract 1953: Association between genetic ancestry and all-cause mortality among Black and White ever-smokers in the PLCO cohort

Abstract 6453: Lifestyle and environmental factors in relation to colorectal cancer risk and survival by colibactin tumor mutational signature status

Abstract 5925: Prevalence of clonal hematopoiesis in patients with monoclonal gammopathy of undetermined significance

Abstract 129: Determine the genetic similarity of synchronous endometrial and ovarian cancers with variants in polyguanine sequences

Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy

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