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Journal Articles

Abstract 5682: Synergism of PARP inhibitor and MET inhibitor in multiple cancer types with intrinsic and acquired PARP inhibitor resistances

Mei-Kuang Chen, Weiya Xia, Qiongzhu Dong, Yi Du, Hung-Ling Wang, Coya Tapia, Yongkun Wei, Ye Han, Yu-Yi Chu, Clinton Yam, Yuan Gao, Yu-Han Wang, Funda Meric-Bernstam, Jinsong Liu, Shao-Chun Wang, Dihua Yu, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5682.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5682
Published: 15 August 2020
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Journal Articles

Abstract 845: c-MET nuclear transportation via membrane-bounded retrograde trafficking in breast cancer cells

Mei-Kuang Chen, Yi Du, Linlin Sun, Jennifer L. Hsu, Yu-Han Wang, Yuan Gao, Jiaxing Huang, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 845.
DOI: https://doi.org/10.1158/1538-7445.AM2019-845
Published: 01 July 2019
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Journal Articles

Abstract LB-258: EGFR and c-MET cooperate to enhance PARP inhibitor resistance in hepatocellular carcinoma

Qiongzhu Dong, Yi Du, Xixi Zhao, Hui Li, Chunxiao Liu, Yongkun Wei, Mien-chie Hung
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-258.
DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-258
Published: 01 July 2019
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Journal Articles

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

Qiongzhu Dong, Yi Du, Hui Li, Chunxiao Liu, Yongkun Wei, Mei-Kuang Chen, Xixi Zhao, Yu-Yi Chu, Yufan Qiu, Lunxiu Qin, Hirohito Yamaguchi, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2019) 79 (4): 819–829.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-1273
Published: 15 February 2019
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Includes: Supplementary data
Journal Articles

Abstract 4063: Design and synthesis of indole derivatives as ABCG2 mediated resistance reversal agents

Chao-Yun Cai, Hong Zhai, Zi-Ning Lei, Bao-Li Chen, Zhao-Yi Du, Yun-Kai Zhang, Yi-Jun Wang, Bo Wang, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4063.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4063
Published: 01 July 2017
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Journal Articles

Abstract 3028: Reactive oxygen species induced nuclear translocation of c-MET via INTERNET mechanism

Mei-Kuang Chen, Yi Du, Yu-Yi Chu, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3028.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3028
Published: 01 July 2017
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Journal Articles

Abstract 1051: EGFR inhibitors attenuate caspase-independent cell death and confer negative effects on cisplatin .

Hirohito Yamaguchi, Jennifer L. Hsu, Chun-Te Chen, Ying-Nai Wang, Ming-Chuan Hsu, Shih-Shin Chang, Yi Du, How-Wen Ko, Roy S. Herbst, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1051.
DOI: https://doi.org/10.1158/1538-7445.AM2013-1051
Published: 15 April 2013
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Journal Articles

Abstract 1230: Syntaxin 6- and microtubule-mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR

Yi Du, Jia Shen, Jennifer L. Hsu, Zhenbo Han, Ying-Nai Wang, Hirohito Yamaguchi, Stephanie A. Miller, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1230.
DOI: https://doi.org/10.1158/1538-7445.AM2012-1230
Published: 15 April 2012
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Journal Articles

Abstract 4051: EGF receptor trafficking from the cell surface to the nucleus through the Golgi, ER, and nuclear envelope

Ying-Nai Wang, Hirohito Yamaguchi, Longfei Huo, Yi Du, Hong-Jen Lee, Heng-Huan Lee, Hongmei Wang, Jung-Mao Hsu, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4051.
DOI: https://doi.org/10.1158/1538-7445.AM2011-4051
Published: 15 April 2011
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Journal Articles

Activation of Murine Double Minute 2 by Akt in Mammary Epithelium Delays Mammary Involution and Accelerates Mammary Tumorigenesis

Xiaoyun Cheng, Weiya Xia, Jer-Yen Yang, Jennifer L. Hsu, Jing-Yu Lang, Chao-Kai Chou, Yi Du, Hui-Lung Sun, Shannon L. Wyszomierski, Gordon B. Mills, William J. Muller, Dihua Yu, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2010) 70 (19): 7684–7689.
DOI: https://doi.org/10.1158/0008-5472.CAN-09-3231
Published: 29 September 2010
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Includes: Supplementary data
Journal Articles

Activation of FOXO3a Is Sufficient to Reverse Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor Chemoresistance in Human Cancer

Jer-Yen Yang, Chun-Ju Chang, Weiya Xia, Yan Wang, Kwok-Kin Wong, Jeffrey A. Engelman, Yi Du, Michael Andreeff, Gabriel N. Hortobagyi, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2010) 70 (11): 4709–4718.
DOI: https://doi.org/10.1158/0008-5472.CAN-09-4524
Published: 01 June 2010
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Includes: Supplementary data
Journal Articles

Abstract #2721: Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

Weiya Xia, Yongkun Wei, Yi Du, Jinsong Liu, Bin Chang, Yung-Luen Yu, Long-Fei Huo, Stephanie Miller, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2721.
Published: 01 May 2009
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Journal Articles

Nuclear transport of EGFR is through the integral trafficking from the endoplasmic reticulum to the nuclear envelope

Ying-Nai Wang, Hirohito Yamaguchi, Yi Du, Longfei Huo, Jung-Mao Hsu, Hongmei Wang, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3501.
Published: 01 May 2008
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