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Journal Articles

Abstract PO1-06-09: Phase 2 Trial with Safety Run-In of Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast CancersBig Ten Cancer Research Consortium BTCRC-BRE18-337

Sneha Phadke, Kari Wisinski, Oana Danciu, Ami Shah, Menggang Yu, Yi Chen, Kathy Miller, Mark Burkard
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-06-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-06-09
Published: 02 May 2024
View article titled, Abstract PO1-06-09: Phase 2 Trial with Safety Run-In of Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast CancersBig Ten Cancer Research Consortium BTCRC-BRE18-337
Journal Articles

Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

Chih-Yi Chen, Yu-Ching Huang, Wen-Hsiu Su, Yi-Ting Liu, Chi-Sheng Chen, Chia-Yang Li, Kun-Che Chang, Chia-Yen Dai, Shu-Chi Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5773.
https://doi.org/10.1158/1538-7445.AM2024-5773
Published: 22 March 2024
View article titled, Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma
Journal Articles

Abstract 3761: A modified SELEX enables the efficient identification of DNA aptamers with potential for specific cancer targeting

Yang Lin, Cho-Yi Chen, Zhi-Qian Lin, Bing-Hong Chen, Yi-Chen Sun, Kai-Feng Hung
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3761.
https://doi.org/10.1158/1538-7445.AM2024-3761
Published: 22 March 2024
View article titled, Abstract 3761: A modified SELEX enables the efficient identification of DNA aptamers with potential for specific cancer targeting
Journal Articles

Abstract 3130: In vitro characterization of a novel TROP2-targeting antibody-drug conjugate OBI-992

Tzer-Min Kuo, Ting-Yu Chang, Jye-Yu Huang, Wei-Chien Tang, Chun-Jung Lin, Yi-Chen Wu, Chi-Huan Lu, Hao-Cheng Weng, Yu-Jung Chen, Yu-Hsuan Tsao, Cheng-Yen Wei, Lifen Shen, Wan-Fen Li, Ming-Tain Lai
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3130.
https://doi.org/10.1158/1538-7445.AM2024-3130
Published: 22 March 2024
View article titled, Abstract 3130: <em>In vitro</em> characterization of a novel TROP2-targeting antibody-drug conjugate OBI-992
Journal Articles

Abstract 675: Targeting Bcl-2/Bcl-xl for small cell lung cancer treatment with LP-118

Ling-Ling Lee, Huan Chen, Cong Zhu, Yao Chen, Brianna Feldmeier, Yue Shen, Yu Chen, Stephen P. Anthony, Fenlai Tan, Yi Chen, Bing Dai
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 675.
https://doi.org/10.1158/1538-7445.AM2024-675
Published: 22 March 2024
View article titled, Abstract 675: Targeting Bcl-2/Bcl-xl for small cell lung cancer treatment with LP-118
Journal Articles

Abstract 1913: KD5005: HER-2 dependent strong potent anti-tumor activity of an anti-HER-2 mAb-TNFaimmunocytokine

YI CHEN, PENG LI, GUOBO FANG, HENG WU, CHI ZHANG, ZELING CAI
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1913.
https://doi.org/10.1158/1538-7445.AM2024-1913
Published: 22 March 2024
View article titled, Abstract 1913: KD5005: HER-2 dependent strong potent anti-tumor activity of an anti-HER-2 mAb-TNFaimmunocytokine
Journal Articles

Abstract 1527: Exploring the role of tertiary lymphoid structure in the tumor microenvironment of cholangiocarcinoma

Shin-Yi Chung, Ming-Huang Chen, Yi-Chen Yeh, Yu-Chan Chang, Yu-Cha Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1527.
https://doi.org/10.1158/1538-7445.AM2024-1527
Published: 22 March 2024
View article titled, Abstract 1527: Exploring the role of tertiary lymphoid structure in the tumor microenvironment of cholangiocarcinoma
Journal Articles

Abstract 1520: A novel cluster of cytolytic alpha/beta TCR+CD4−CD8−T cells originating from CD8+T cells with potent innate-like T cell killing ability: implicating adoptive T cell transfer therapy for hepatocellular carcinoma

Cheng-Heng Wu, Te-Wei Tseng, Chen-Yang Huang, Ping-Hsun Ou, Yi-Chen Lin, Pin-Jung Chen, Po-Ting Lin, Chan-Keng Yang, Wei Teng, Tsung-Han Wu, Yung-Chang Lin, Chun-Yen Lin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1520.
https://doi.org/10.1158/1538-7445.AM2024-1520
Published: 22 March 2024
View article titled, Abstract 1520: A novel cluster of cytolytic alpha/beta TCR<sup>+</sup>CD4<sup>−</sup>CD8<sup>−</sup>T cells originating from CD8<sup>+</sup>T cells with potent innate-like T cell killing ability: implicating adoptive T cell transfer therapy for hepatocellular carcinoma
Journal Articles

Abstract 297: Role of purine metabolism in CLL cell pathobiology and CLL disease progression

Sutapa Sinha, Weiguo Han, Zhiquan Wang, Kari G. Rabe, Susan L. Slager, Chantal E. McCabe, Daniel R. O'Brien, Sameer A. Parikh, Esteban Braggio, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Bing Dai, Yue Shen, Neil E. Kay
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 297.
https://doi.org/10.1158/1538-7445.AM2024-297
Published: 22 March 2024
View article titled, Abstract 297: Role of purine metabolism in CLL cell pathobiology and CLL disease progression
Journal Articles

Abstract 1350: KD6001: A promising new anti-CTLA-4 human monoclonal antibody for cancer therapy

Yi Chen, Peng Li, Guobo Fang, Heng Wu, Chi Zhang, Zeling Cai
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1350.
https://doi.org/10.1158/1538-7445.AM2024-1350
Published: 22 March 2024
View article titled, Abstract 1350: KD6001: A promising new anti-CTLA-4 human monoclonal antibody for cancer therapy
Journal Articles

Abstract 3348: Identification of circSPINT2 as a tumor suppressive circular RNA sensitizing lung cancer to 3rd generation EGFR-TKI treatment

Mong-Lien (Lotus) Wang, Shih-Hwa Shiou, Yi-Chen Chen, Ming-Long Tsai, Nalini Devi Verusingam, Alan Han-Kiat Ong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3348.
https://doi.org/10.1158/1538-7445.AM2024-3348
Published: 22 March 2024
View article titled, Abstract 3348: Identification of circSPINT2 as a tumor suppressive circular RNA sensitizing lung cancer to 3<sup>rd</sup> generation EGFR-TKI treatment
Journal Articles

Abstract 3542: The Chemical Probes Portal: An essential resource providing expert advice on chemical tools for cancer research

Domenico Sanfelice, Albert Antolin, Alisa Crisp, Yi Chen, Paul Brennan, Susanne Müller, Bissan Al-Lazikani, Aled Edwards, Paul Workman
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3542.
https://doi.org/10.1158/1538-7445.AM2024-3542
Published: 22 March 2024
View article titled, Abstract 3542: The Chemical Probes Portal: An essential resource providing expert advice on chemical tools for cancer research
Journal Articles

Abstract 349: LncRNA Myca controls hepatocellular carcinoma growth and progression

Hsin-Yi Chen, Yu-Yun Weng, Wei-Chien Yuan, Yu-Ru Lee
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 349.
https://doi.org/10.1158/1538-7445.AM2023-349
Published: 04 April 2023
View article titled, Abstract 349: LncRNA <em>Myca</em> controls hepatocellular carcinoma growth and progression
Journal Articles

Abstract 5148: Interrogating immuno-oncological interactions in the tumor microenvironment

Ben Patterson, g-Yi Chen, Nicolas Fernandez, Leiam Colbert, Jiang He
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5148.
https://doi.org/10.1158/1538-7445.AM2023-5148
Published: 04 April 2023
View article titled, Abstract 5148: Interrogating immuno-oncological interactions in the tumor microenvironment
Journal Articles

Abstract 343: Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men

Ching-Yi Chen, Pei-Ying Wu, Michelle Van Scoyk, Stephanie A. Simko, Chu-Fang Chou, Robert A. Winn
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 343.
https://doi.org/10.1158/1538-7445.AM2023-343
Published: 04 April 2023
View article titled, Abstract 343: Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
Journal Articles

Abstract 6045: Role of PP2A methylation on methionine dependence of cancer

Anna Andronicos, Da-Wei Lin, Yi-Chen Su, Mari Ishak Gabra, Mei Kong, Peter Kaiser
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6045.
https://doi.org/10.1158/1538-7445.AM2023-6045
Published: 04 April 2023
View article titled, Abstract 6045: Role of PP2A methylation on methionine dependence of cancer
Journal Articles

Abstract 5885: A pathway-centric approach to characterising tumour heterogeneity and cell diversity across multiple cancer types

Leiam Colbert, Benjamin Patterson, Cheng Yi Chen, Nicolas Fernandez, Jiang He
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5885.
https://doi.org/10.1158/1538-7445.AM2023-5885
Published: 04 April 2023
View article titled, Abstract 5885: A pathway-centric approach to characterising tumour heterogeneity and cell diversity across multiple cancer types
Journal Articles

Abstract 3381: Analytical performance of an ultra-sensitive, tumor-informed liquid biopsy platform for molecular residual disease detection and clinical guidance

Rui Chen, Gábor Bartha, John Lyle, Jason Harris, Sean M. Boyle, Josette Northcott, Dan Norton, Rachel M. Pyke, Fábio C. Navarro, Charles W. Abbott, Christian Haudenschild, Rose Santiago, Darren Nichols, Stephanie Huang, Christopher Nelson, Manju Chinnappa, Yi Chen, Yuker Wang, Laurie Goodman, Qi Zhang, Manqing Hong, Xiaoji Chen, Erin Ayash, Nitin Udar, Sebastian Saldivar, Jian Yan, John West, Richard O. Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3381.
https://doi.org/10.1158/1538-7445.AM2023-3381
Published: 04 April 2023
View article titled, Abstract 3381: Analytical performance of an ultra-sensitive, tumor-informed liquid biopsy platform for molecular residual disease detection and clinical guidance
Journal Articles

Abstract 4332: Characterizing cancer-associated fibroblasts in prostate cancer using Vizgen’s MERSCOPETM Platform

Ben Patterson, Cheng-Yi Chen, Nicolas Fernandez, Simran Kaushal, Leiam Colbert, Jiang He
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4332.
https://doi.org/10.1158/1538-7445.AM2023-4332
Published: 04 April 2023
View article titled, Abstract 4332: Characterizing cancer-associated fibroblasts in prostate cancer using Vizgen’s MERSCOPE<sup>TM</sup> Platform
Journal Articles

Abstract 2353: PTGES is involved in the myofibroblast differentiation

Yi-Fang Yang, Yi-Chen Lee, Min-Hsi Lin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2353.
https://doi.org/10.1158/1538-7445.AM2023-2353
Published: 04 April 2023
View article titled, Abstract 2353: PTGES is involved in the myofibroblast differentiation