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Journal Articles

Abstract 5373: Intact regulation of G1/S transition renders esophageal squamous cell carcinomas sensitive to PI3Kα inhibitors by blocking SKP2-mediated p21 degradation

Yuxiang Wang, Xu Zhang, Xi Zhang, Yanyan Shen, Qingyang Ma, Yuemei Qiao, Yi Wang, Biyu Yang, Lan Xu, Gaoxiang Ge, Landian Hu, Xiangyin Kong, Chunhao Yang, Jian Ding, Yi Chen, Linghua Meng
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5373.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5373
Published: 15 June 2022
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Journal Articles

Abstract 5091: The early change of serum interleukin 14α levels predicts the response to anti-PD-1 therapy in cancer

Bu Hai Wang, Cai Yue Chen, Xian Zhang, Yu Xiang Huang, Yi Chun Zeng, Lei Li, Mao Qi Wang, Jing Liang Guo, Qiu Xian Li, Long Shen, Juan J. Gu, Yi Chen Liang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5091.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5091
Published: 15 June 2022
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Journal Articles

Abstract 5436: HH2853 is a selective small molecular dual inhibitor of EZH1/2 with potent anti-tumor activities

Xu-Xing Chen, Qian-Qian Shen, Zhao Zhao, Yan-Fen Fang, Jun-Yu Yang, Ying-Lei Gao, Lei Liu, Yixiang Zhang, Yi Chen, Leping Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5436.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5436
Published: 15 June 2022
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Journal Articles

Abstract PS18-40: The genomic landscape of Chinese breast cancer

Qiuting You, Jianli Zhao, Kai Chen, Yi Chen, Minhua Zeng, Biaolin Wen, Linxiaoxiao Ding, Fengxi Su
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-40.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS18-40
Published: 15 February 2021
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Journal Articles

Abstract PS4-10: Serial MRI and pathology combined to select candidates for therapy de-escalation in the I-SPY 2 TRIAL

Sara J Venters, Wen Li, Denise M Wolf, Jodi M Carter, Molly E Klein, Kamaljeet Singh, Kimmie Rabe, I Tolgay Ocal, David Newitt, Christina Yau, Natsuko Onishi, Jessica Gibbs, Sunati Sahoo, Shuko Harada, Laila Khazai, Malini Harigopal, Alexander D Borowsky, Gregor Krings, Ronald Balassanian, Yunn-Yi Chen, Kimberley Cole, Sonal Shad, Barbara LeStage, Amy Delson, Sandra Finestone, Lamorna Brown-Swigart, I-SPY 2 Imaging Working Group, I-SPY 2 TRIAL Consortium, Laura Esserman, Laura van ‘t Veer, W Fraser Symmans, Nola M Hylton
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS4-10
Published: 15 February 2021
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Journal Articles

Abstract PS4-09: Pathologic features of the inter-regimen biopsy predict response to neoadjuvant therapy in the I-SPY 2 TRIAL

Jodi M Carter, Molly E Klein, Sara J Venters, Kimmie Rabe, I Tolgay Ocal, Kamaljeet Singh, Denise M Wolf, Sunati Sahoo, Shuko Harada, Laila Khazai, Malini Harigopal, Alexander D Borowsky, Gregor Krings, Ronald Balassanian, Yunn-Yi Chen, Kimberley Cole, Sonal Shad, Amy Delson, Lamorna Brown-Swigart, I-SPY 2 TRIAL Consortium, Laura Esserman, Laura van ‘t Veer, W Fraser Symmans
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS4-09
Published: 15 February 2021
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Journal Articles

Abstract 417: Developing mouse models to dissect the function of a driver gene epimutation in lung tumorigenesis

Li Yang, Anusha Mandala, Yi Chen, Lanlan Shen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 417.
DOI: https://doi.org/10.1158/1538-7445.AM2020-417
Published: 15 August 2020
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Journal Articles

Abstract 4072: Analysis of clinical BRCA1/2 reversions identifies hotspot mutations and predicted neoantigens associated with therapy resistance

Stephen Pettitt, Jessica Frankum, Marco Punta, Stefano Lise, John Alexander, Yi Chen, Syed Haider, Andrew N. Tutt, Christopher J. Lord
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4072.
DOI: https://doi.org/10.1158/1538-7445.AM2020-4072
Published: 15 August 2020
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Journal Articles

Abstract 3760: HH2710, a highly potent and selective erk1/2 inhibitor for the treatment of mapk mutant tumors

Lei Li, Min Huang, Leping Li, Yi Chen, Shuai Tang, Yi Su, Ruiping Dong, Jian Ding, Meiyu Geng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3760.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3760
Published: 15 August 2020
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Journal Articles

Abstract P3-08-16: The impact of residual ductal carcinoma in situ on breast cancer recurrence in the neoadjuvant I-SPY2 TRIAL

Marie Osdoit, Christina Yau, W. Fraser Symmans, Judy C. Boughey, Smita M. Asare, Ron Balassanian, Jodi M. Carter, Yunn-Yi Chen, Kimberly Cole, Laila Khazai, Molly Klein, Dina Kokh, Gregor Krings, Sunati Sahoo, Gretchen Ahrendt, Akiko Chiba, Cheryl Ewing, Constantine Godellas, Nora Jaskowiak, Brigid Killelea, Helen Krontiras, Rachael Lancaster, Julie Lang, M. Catherine Lee, Arpana Naik, Roshni Rao, Julia Tchou, Shannon Tierney, Eleni Tousimis, Tod Tuttle, Anne Wallace, I-SPY 2 TRIAL Consortium, Bev Parker, Laura J. Esserman, Rita A. Mukhtar
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-08-16.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P3-08-16
Published: 15 February 2020
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Journal Articles

Abstract P4-12-19: Impact of delaying initiation of RT following definitive surgery or following adjuvant chemotherapy on survival outcomes in breast cancer patients

Lu Cao, Jia-Yi Chen
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-12-19.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P4-12-19
Published: 15 February 2020
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Journal Articles

Abstract P2-20-02: Site of recurrence after neoadjuvant therapy: Clues to biology and impact on endpoints

Christina Yau, Angela DeMichele, W. Fraser Symmans, Lajos Pusztai, Douglas Yee, Amy S. Clark, Christos Hatzis, Jeffrey B. Matthews, Jodi Carter, Yunn-Yi Chen, Kimberly Cole, Laila Khazai, Molly Klein, Dina Kokh, Gregor Krings, Sunati Sahoo, Kathy S. Albain, A. Jo Chien, Kirsten K. Edmiston, Anthony D. Elias, Erin D. Ellis, David M. Euhus, Heather S. Han, Claudine Isaacs, Qamar J. Khan, Julie E. Lang, Janice Lu, Jane L. Meisel, Zaha Mitri, Rita Nanda, Donald W. Northfelt, Tara Sanft, Erica Stringer-Reasor, Rebecca K. Viscusi, Anne M. Wallace, Rachel Yung, Nola M. Hylton, Judy C. Boughey, Michelle E. Melisko, Jane Perlmutter, Hope S. Rugo, Richard Schwab, Laura J. van' t Veer, Donald A. Berry, Laura J. Esserman
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-20-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-20-02
Published: 15 February 2020
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Journal Articles

Abstract P6-10-02: Assessing biomarkers to inform treatment de-escalation: Mid-treatment biopsy cellularity predicts pCR in the I-SPY 2 Trial

Sara J Venters, Denise M Wolf, Lamorna Brown-Swigart, Christina Yau, Amy L Delson, Bev Parker, Ron Balassanian, Jodi Carter, Yunn-Yi Chen, Kimberly Cole, Laila Khazai, Molly Klein, Dina Kokh, Gregor Krings, Sunati Sahoo, Jane Wei, I-SPY 2 TRIAL Consortium, Laura J Esserman, Laura J van't Veer, W Fraser Symmans
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-10-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P6-10-02
Published: 15 February 2020
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Journal Articles

Abstract OT3-12-02: Effect of physical activity training on cardiovascular function, immune cells, quality of life during breast cancer chemotherapy in Taiwan

Chia-Ming Hsieh, Kuan-Der Lee, Meng-Hsiu Wu, Ning-Chiang Yang, Hsin-Yi Chen, I-Shiang Tzeng
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): OT3-12-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-OT3-12-02
Published: 15 February 2020
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Journal Articles

Abstract 5197: Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression

Zong-long Hu, Ya-fang Wang, Yi Su, Yan-yan Shen, Yan-fen Fang, Jian Ding, Yi Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5197.
DOI: https://doi.org/10.1158/1538-7445.AM2019-5197
Published: 01 July 2019
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Journal Articles

Abstract 2210: Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance

Tao Zhang, Rong Qu, Chengbin Chen, Linjiang Tong, Fang Feng, Yi Chen, Meiyu Geng, Ke Ding, Hua Xie, Jian Ding
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2210.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2210
Published: 01 July 2019
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Journal Articles

Abstract 4690: Multi-sample automation of the CLARITY technology for the processing of 3D volumes of tissue

Sharla L. White, Yi Chen, Qi Shen, Laurie J. Goodman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4690.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4690
Published: 01 July 2019
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Abstract 4403: Regulation of SATB2 via miR-31 in Ni-induced malignant cell transformation

Qiao Yi Chen, Yusha Zhu, Ashley Jordan, Jinquan Li, Hong Sun, Thomas Kluz, Max Costa
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4403.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4403
Published: 01 July 2019
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Abstract LB-259: EZH2 inhibitors abrogate upregulation of H3K27me3 by CDK9 inhibitors and potentiate its antitumor activity in DLBCL

Shao Xie, Fan Wei, Yiming Sun, Yinglei Gao, Jian Ding, Yi Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-259.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-259
Published: 01 July 2018
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Abstract LB-268: Discovery of clinical candidate methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) : A highly potent and selective PI3K alpha inhibitor for the treatment of advanced solid tumors

Haoyue Xiang, Xiang Wang, Yanhong Chen, Xi Zhang, Yi Chen, Cun Tan, Yi Wang, Jian Ding, Ling-Hua Meng, Chunhao Yang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-268.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-268
Published: 01 July 2018
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