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Journal Articles

Abstract 1190: The enrichment of CD8⁺ T cell in TP53 pathway wild-type microsatellite stable colorectal cancer

Yi Cai, Feilong Zhao, Xiaochen Zhao, Yuezong Bai

Cancer Res (2021) 81 (13_Supplement): 1190.

https://doi.org/10.1158/1538-7445.AM2021-1190

Published: 01 July 2021

View article titled, Abstract 1190: The enrichment of CD8<sup>+</sup> T cell in TP53 pathway wild-type microsatellite stable colorectal cancer

Journal Articles

Abstract 3361: Discovery and preclinical characterizations of a humanized anti-claudin 18.2 antibody SPX-101

Guidong Zhu, Jichun Ma, Jingdong Ye, Jingdong Qin, Yi Cai

Cancer Res (2020) 80 (16_Supplement): 3361.

https://doi.org/10.1158/1538-7445.AM2020-3361

Published: 15 August 2020

View article titled, Abstract 3361: Discovery and preclinical characterizations of a humanized anti-claudin 18.2 antibody SPX-101

Journal Articles

Abstract 534: Discovery of an anti-claudin18.2/anti-PD-L1 bispecific antibody SPX-301 in the SMARTOP^TM format

Guidong Zhu, Jingdong Ye, Jichun Ma, Jingdong Qin, Yi Cai

Cancer Res (2020) 80 (16_Supplement): 534.

https://doi.org/10.1158/1538-7445.AM2020-534

Published: 15 August 2020

View article titled, Abstract 534: Discovery of an anti-claudin18.2/anti-PD-L1 bispecific antibody SPX-301 in the SMARTOP<sup>TM</sup> format

Journal Articles

Abstract 947: Defining UHRF1 domains that support maintenance of human colon cancer DNA methylation and tumorigenicity

Xiangqian Kong, Jie Chen, Wenbing Xie, Stephen M. Brown, Yi Cai, Kaichun Wu, Daiming Fan, Yongzhan Nie, Yong Tao, Ray-Whay Chiu Yen, Hariharan Easwaran, Michael J. Topper, Scott B. Rothbart, Limin Xia, Stephen B. Baylin

Cancer Res (2019) 79 (13_Supplement): 947.

https://doi.org/10.1158/1538-7445.AM2019-947

Published: 01 July 2019

View article titled, Abstract 947: Defining UHRF1 domains that support maintenance of human colon cancer DNA methylation and tumorigenicity

Journal Articles

Abstract IA13: Combination of DNA methyltransferase and PARP inhibitors as a novel therapy strategy for multiple cancers: Key data in AML and triple negative breast cancer

Nidal Muvarak, Khadiza Chowdhury, Carine Robert, Xia Limin, Eun Yong Choi, Yi Cai, Marina Bellani, Michael Seidman, Maria R. Baer, Rena Lapidus, Stephen B. Baylin, Feyruz V. Rassool

Cancer Res (2017) 77 (22_Supplement): IA13.

https://doi.org/10.1158/1538-7445.NEWFRONT17-IA13

Published: 14 November 2017

View article titled, Abstract IA13: Combination of DNA methyltransferase and PARP inhibitors as a novel therapy strategy for multiple cancers: Key data in AML and triple negative breast cancer

Journal Articles

Abstract LB-205: Combination of DNA methyltransferase and PARP inhibitors as a novel therapy strategy for poor prognosis acute myeloid leukemia and triple-negative breast cancers

Feyruz V. Rassool, Nidal Muvarak, Khadiza Chowdury, Carine Robert, Limin Xia, Eun Yong Choi, Yi Cai, Marina Bellani, Ying Zou, Michael Seidman, Søren Bentzen, Maria Baer, Rena Lapidus, Stephen B. Baylin

Cancer Res (2016) 76 (14_Supplement): LB-205.

https://doi.org/10.1158/1538-7445.AM2016-LB-205

Published: 15 July 2016

View article titled, Abstract LB-205: Combination of DNA methyltransferase and PARP inhibitors as a novel therapy strategy for poor prognosis acute myeloid leukemia and triple-negative breast cancers

Journal Articles

Abstract LB-150: Genetic depletion of DNMT1 reveals a DNMT1 threshold controlling DNA methylation in human cells

Yi Cai, Hsing-chen Tsai, Ray-whay Yen, Limin Xia, Yang Zhang, Stephen Baylin

Cancer Res (2015) 75 (15_Supplement): LB-150.

https://doi.org/10.1158/1538-7445.AM2015-LB-150

Published: 01 August 2015

View article titled, Abstract LB-150: Genetic depletion of DNMT1 reveals a DNMT1 threshold controlling DNA methylation in human cells

Journal Articles

Abstract 2864: Acetylation regulates TET2 stability and enzymatic activity

Yang Zhang, Yi Cai, Wenbing Xie, Hariharan Easwaran, Stephen B. Baylin

Cancer Res (2015) 75 (15_Supplement): 2864.

https://doi.org/10.1158/1538-7445.AM2015-2864

Published: 01 August 2015

View article titled, Abstract 2864: Acetylation regulates TET2 stability and enzymatic activity

Journal Articles

Abstract 452: Murine prostate tumors recruit endogenous, thymic-derived regulatory T cells which are redistributed following castration.

Daniel Leventhal, Sven Malchow, Yi Cai, Donald Vander Griend, Peter Savage

Cancer Res (2013) 73 (8_Supplement): 452.

https://doi.org/10.1158/1538-7445.AM2013-452

Published: 15 April 2013

View article titled, Abstract 452: Murine prostate tumors recruit endogenous, thymic-derived regulatory T cells which are redistributed following castration.

Journal Articles

Abstract LB-386: The NuRD complex cooperates with DNMTs to maintain silencing of colorectal tumor suppressor genes.

Yi Cai, Ernst-Jan Geutjes, Paul Roepman, Li-Rong Yu, Janneke V. Blijswijk, Wei Wang, Helai Mohammad, Iris de Rink, Stephen Baylin, Rene Bernards

Cancer Res (2012) 72 (8_Supplement): LB-386.

https://doi.org/10.1158/1538-7445.AM2012-LB-386

Published: 15 April 2012

View article titled, Abstract LB-386: The NuRD complex cooperates with DNMTs to maintain silencing of colorectal tumor suppressor genes.

Journal Articles

Abstract 3271: Targeting fibroblast growth factor receptor 4 decreases prostate cancer growth and metastasis

Shu Feng, Wendong Yu, Yi Cai, Jianghua Wang, Michael M. Ittmann

Cancer Res (2012) 72 (8_Supplement): 3271.

https://doi.org/10.1158/1538-7445.AM2012-3271

Published: 15 April 2012

View article titled, Abstract 3271: Targeting fibroblast growth factor receptor 4 decreases prostate cancer growth and metastasis

Journal Articles

Abstract 995: Transient low doses of DNA demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

Cancer Res (2012) 72 (8_Supplement): 995.

https://doi.org/10.1158/1538-7445.AM2012-995

Published: 15 April 2012

View article titled, Abstract 995: Transient low doses of DNA demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

Journal Articles

Abstract 957: TMPRSS2:ERG overexpression limits vitamin D receptor action in prostate cancer cells

Jung-Sun Kim, Jianghua Wang, Yi Cai, Long-Jiang Shao, Michael Ittmann, Nancy Weigel

Cancer Res (2012) 72 (8_Supplement): 957.

https://doi.org/10.1158/1538-7445.AM2012-957

Published: 15 April 2012

View article titled, Abstract 957: TMPRSS2:ERG overexpression limits vitamin D receptor action in prostate cancer cells

Journal Articles

Abstract LB-185: Oxidative damage targets complexes containing DNA methyltransferases, SIRT1 and polycomb members to promoter CpG islands

Heather M. O'Hagan, Wei Wang, Subhojit Sen, Stella S. Lee, Eriko G. Clements, Yi Cai, Leander Van Neste, Hariharan Easwaran, Stephen B. Baylin

Cancer Res (2011) 71 (8_Supplement): LB-185.

https://doi.org/10.1158/1538-7445.AM2011-LB-185

Published: 15 April 2011

View article titled, Abstract LB-185: Oxidative damage targets complexes containing DNA methyltransferases, SIRT1 and polycomb members to promoter CpG islands

Journal Articles

Abstract 1106: Fibroblast growth factor FGF19 signaling promotes prostate cancer progression

Shu Feng, Wendong Yu, Yi Cai, Jianghua Wang, Patricia D. Castro, Michael M. Ittmann

Cancer Res (2011) 71 (8_Supplement): 1106.

https://doi.org/10.1158/1538-7445.AM2011-1106

Published: 15 April 2011

View article titled, Abstract 1106: Fibroblast growth factor FGF19 signaling promotes prostate cancer progression

Journal Articles

Activation of NF-κB by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

Jianghua Wang, Yi Cai, Long-jiang Shao, Javed Siddiqui, Nallasivam Palanisamy, Rile Li, Chengxi Ren, Gustavo Ayala, Michael Ittmann

Cancer Res (2011) 71 (4): 1325–1333.

https://doi.org/10.1158/0008-5472.CAN-10-2210

Published: 14 February 2011

View article titled, Activation of NF-κB by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

Includes: Supplementary data

Journal Articles

Abstract LB-88: Transient exposure to low-dose decitabine and azacytidine reprograms cancer cells to produce a prolonged antitumor response

Hsing-Chen Tsai, Leander Van Neste, Huili Li, Yi Cai, Carine Robert, James J. Shin, Emmanouil Pappou, Ray-Whay Yen, IL Minn, Nita Ahuja, Malcolm V. Brock, Feyruz V. Rassool, Yoon-Young Jang, Saul J. Sharkis, William Matsui, Cynthia A. Zahnow, Stephen B. Baylin

Cancer Res (2010) 70 (8_Supplement): LB-88.

https://doi.org/10.1158/1538-7445.AM10-LB-88

Published: 15 April 2010

View article titled, Abstract LB-88: Transient exposure to low-dose decitabine and azacytidine reprograms cancer cells to produce a prolonged antitumor response

Journal Articles

Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation

Helai P. Mohammad, Yi Cai, Kelly M. McGarvey, Hariharan Easwaran, Leander Van Neste, Joyce E. Ohm, Heather M. O'Hagan, Stephen B. Baylin

Cancer Res (2009) 69 (15): 6322–6330.

https://doi.org/10.1158/0008-5472.CAN-09-0065

Published: 29 July 2009

View article titled, Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation

Includes: Supplementary data

Journal Articles

GGAP2/PIKE-A Directly Activates Both the Akt and Nuclear Factor-κB Pathways and Promotes Prostate Cancer Progression

Yi Cai, Jianghua Wang, Rile Li, Gustavo Ayala, Michael Ittmann, Mingyao Liu

Cancer Res (2009) 69 (3): 819–827.

https://doi.org/10.1158/0008-5472.CAN-08-2537

Published: 29 January 2009

View article titled, GGAP2/PIKE-A Directly Activates Both the Akt and Nuclear Factor-κB Pathways and Promotes Prostate Cancer Progression

Includes: Supplementary data

Journal Articles

Pleiotropic Biological Activities of Alternatively Spliced TMPRSS2/ERG Fusion Gene Transcripts

Jianghua Wang, Yi Cai, Wendong Yu, Chengxi Ren, David M. Spencer, Michael Ittmann

Cancer Res (2008) 68 (20): 8516–8524.

https://doi.org/10.1158/0008-5472.CAN-08-1147

Published: 15 October 2008

View article titled, Pleiotropic Biological Activities of Alternatively Spliced TMPRSS2/ERG Fusion Gene Transcripts

Includes: Supplementary data

NARROW

Abstract 1190: The enrichment of CD8⁺ T cell in TP53 pathway wild-type microsatellite stable colorectal cancer

Abstract 3361: Discovery and preclinical characterizations of a humanized anti-claudin 18.2 antibody SPX-101

Abstract 534: Discovery of an anti-claudin18.2/anti-PD-L1 bispecific antibody SPX-301 in the SMARTOP^TM format

Abstract 947: Defining UHRF1 domains that support maintenance of human colon cancer DNA methylation and tumorigenicity

Abstract IA13: Combination of DNA methyltransferase and PARP inhibitors as a novel therapy strategy for multiple cancers: Key data in AML and triple negative breast cancer

Abstract LB-205: Combination of DNA methyltransferase and PARP inhibitors as a novel therapy strategy for poor prognosis acute myeloid leukemia and triple-negative breast cancers

Abstract LB-150: Genetic depletion of DNMT1 reveals a DNMT1 threshold controlling DNA methylation in human cells

Abstract 2864: Acetylation regulates TET2 stability and enzymatic activity

Abstract 452: Murine prostate tumors recruit endogenous, thymic-derived regulatory T cells which are redistributed following castration.

Abstract LB-386: The NuRD complex cooperates with DNMTs to maintain silencing of colorectal tumor suppressor genes.

Abstract 3271: Targeting fibroblast growth factor receptor 4 decreases prostate cancer growth and metastasis

Abstract 995: Transient low doses of DNA demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

Abstract 957: TMPRSS2:ERG overexpression limits vitamin D receptor action in prostate cancer cells

Abstract LB-185: Oxidative damage targets complexes containing DNA methyltransferases, SIRT1 and polycomb members to promoter CpG islands

Abstract 1106: Fibroblast growth factor FGF19 signaling promotes prostate cancer progression

Activation of NF-κB by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

Abstract LB-88: Transient exposure to low-dose decitabine and azacytidine reprograms cancer cells to produce a prolonged antitumor response

Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation

GGAP2/PIKE-A Directly Activates Both the Akt and Nuclear Factor-κB Pathways and Promotes Prostate Cancer Progression

Pleiotropic Biological Activities of Alternatively Spliced TMPRSS2/ERG Fusion Gene Transcripts

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