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Journal Articles

Abstract 5146: Clinical significance of inter-assay discrepancy in PD-L1 expression evaluation for the efficacy of pembrolizumab in advanced NSCLC patients with high PD-L1 expression

Jun Miyakoshi, Jumpei Kashima, Masayuki Shirasawa, Masahiro Torasawa, Yuji Matsumoto, Ken Masuda, Yuki Shinno, Yusuke Okuma, Tatsuya Yoshida, Yasushi Goto, Hidehito Horinouchi, Kouya Shiraishi, Takashi Kohno, Noboru Yamamoto, Yasushi Yatabe, Yuichiro Ohe
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5146.
https://doi.org/10.1158/1538-7445.AM2024-5146
Published: 22 March 2024
View article titled, Abstract 5146: Clinical significance of inter-assay discrepancy in PD-L1 expression evaluation for the efficacy of pembrolizumab in advanced NSCLC patients with high PD-L1 expression
Journal Articles

Abstract 3995: Trastuzumab deruxtecan, antibody-drug conjugate targeting HER2, effectively inhibits growth of patient-derived xenograft model with CIC-rearranged sarcoma

Yuki Kojima, Shigehiro Yagishita, Kazuki Sudo, Tatsunori Shimoi, Shintaro Iwata, Shun-ichi Watanabe, Chitose Ogawa, Akihiko Yoshida, Yasushi Yatabe, Kan Yonemori, Akinobu Hamada
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3995.
https://doi.org/10.1158/1538-7445.AM2023-3995
Published: 04 April 2023
View article titled, Abstract 3995: Trastuzumab deruxtecan, antibody-drug conjugate targeting HER2, effectively inhibits growth of patient-derived xenograft model with CIC-rearranged sarcoma
Journal Articles

Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ

Momoko Tokura, Jun Nakayama, Marta Prieto-Vila, Sho Shiino, Masayuki Yoshida, Tomofumi Yamamoto, Naoaki Watanabe, Shin Takayama, Yutaka Suzuki, Koji Okamoto, Takahiro Ochiya, Takashi Kohno, Yasushi Yatabe, Akihiko Suto, Yusuke Yamamoto
Journal: Cancer Research
Cancer Res (2022) 82 (18): 3236–3248.
https://doi.org/10.1158/0008-5472.CAN-22-0090
Published: 16 September 2022
View article titled, Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma <em>In Situ</em>
Open the PDF for Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma <em>In Situ</em> in another window
Includes: Supplementary data
Journal Articles

Abstract 2185: MicroSEC: Sequence error filter for formalin-fixed and paraffin-embedded samples

Masachika Ikegami, Shinji Kohsaka, Takeshi Hirose, Toshihide Ueno, Satoshi Inoue, Naoki Kanomata, Hideko Yamauchi, Taisuke Mori, Shigeki Sekine, Yoshihiro Inamoto, Yasushi Yatabe, Hiroshi Kobayashi, Sakae Tanaka, Toru Akiyama, Tomotake Okuma, Hiroyuki Mano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2185.
https://doi.org/10.1158/1538-7445.AM2022-2185
Published: 15 June 2022
View article titled, Abstract 2185: MicroSEC: Sequence error filter for formalin-fixed and paraffin-embedded samples
Journal Articles

Abstract 3429: Genetic analysis of pancreatic neuroendocrine neoplasms grade 3

Nobuyuki Kakiuchi, Kenichi Yoshida, Yusuke Shiozawa, Akira Yokoyama, Keisuke Kataoka, Yoshikage Inoue, Yasuhide Takeuchi, Tomonori Hirano, Yoichi Fujii, Hiroo Ueno, Susumu Hijioka, Nobumasa Mizuno, Waki Hosoda, Yasushi Yatabe, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Satoru Miyano, Toshihiko Masui, Shinji Uemoto, Akihiko Yoshizawa, Hironori Haga, Norimitsu Uza, Hiroshi Seno, Yuzo Kodama, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3429.
https://doi.org/10.1158/1538-7445.AM2019-3429
Published: 01 July 2019
View article titled, Abstract 3429: Genetic analysis of pancreatic neuroendocrine neoplasms grade 3
Journal Articles

Abstract 84: Identification of HNRNPLL as a novel metastasis suppressor of colorectal cancer

Masahiro Aoki, Eiichi Sasaki, Kenya Kimura, Koji Komori, Yasuhiro Shimizu, Yasushi Yatabe, Keiichiro Sakuma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 84.
https://doi.org/10.1158/1538-7445.AM2018-84
Published: 01 July 2018
View article titled, Abstract 84: Identification of HNRNPLL as a novel metastasis suppressor of colorectal cancer
Journal Articles

Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma

Smruthy Sivakumar, F. Anthony San Lucas, Tina L. McDowell, Wenhua Lang, Li Xu, Junya Fujimoto, Jianjun Zhang, P. Andrew Futreal, Junya Fukuoka, Yasushi Yatabe, Steven M. Dubinett, Avrum E. Spira, Jerry Fowler, Ernest T. Hawk, Ignacio I. Wistuba, Paul Scheet, Humam Kadara
Journal: Cancer Research
Cancer Res (2017) 77 (22): 6119–6130.
https://doi.org/10.1158/0008-5472.CAN-17-1605
Published: 14 November 2017
View article titled, Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma
Open the PDF for Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 4762: ITPKA expression in lung and other cancers, regulated via gene body methylation, functions as an oncogene

Yi-Wei Wang, Xiaotu Ma, Yu-An Zhang, Mei-Jung Wang, Yasushi Yatabe, Stephen Lam, Luc Girard, Jeou-Yuan Chen, Adi F. Gazdar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4762.
https://doi.org/10.1158/1538-7445.AM2015-4762
Published: 01 August 2015
View article titled, Abstract 4762: ITPKA expression in lung and other cancers, regulated via gene body methylation, functions as an oncogene
Journal Articles

Abstract 277: Multiplex Epstein-Barr virus (EBV) serology in EBV-positive and -negative gastric cancer

M. Constanza Camargo, Angelika Michel, Kyoung-Mee Kim, Keitaro Matsuo, Linda M. Liao, Javier Torres, Jovanny Zabaleta, Margaret L. Gulley, Yasushi Yatabe, Isabel Alvarado-Cabrero, Jolanta Lissowska, Sung Kim, Michael Pawlita, Charles S. Rabkin
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 277.
https://doi.org/10.1158/1538-7445.AM2014-277
Published: 01 October 2014
View article titled, Abstract 277: Multiplex Epstein-Barr virus (EBV) serology in EBV-positive and -negative gastric cancer
Journal Articles

Abstract 441: Functional characterization of recurrent CD74‐NRG1 fusions in lung adenocarcinoma

Dennis Plenker, Lynnette Fernandez-Cuesta, Hirotaka Osada, Ruping Sun, Marc Bos, Juliane Daßler, Gavin Wright, Elisabeth Brambilla, Reinhard Büttner, Sascha Ansen, Stefan Haas, Yasushi Yatabe, Roman K. Thomas
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 441.
https://doi.org/10.1158/1538-7445.AM2014-441
Published: 01 October 2014
View article titled, Abstract 441: Functional characterization of recurrent CD74‐NRG1 fusions in lung adenocarcinoma
Journal Articles

Abstract 4468: Cripto-1 elicits innate resistance to EGFR inhibitors in non-small cell lung cancer harboring EGFR-sensitizing mutations.

Kang-Seo Park, Giaccone Giuseppe, Yisong Wang, Trung Pham, Yongwha Moon, Ji Luo, Liam Changwoo Lee, Tetsuya Mitsudomi, Isamu Okamoto, Yasushi Yatabe, Tony Mok, Mark Raffeld, Liqiang Xi, David S. Salomon, Caterina Bianco
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4468.
https://doi.org/10.1158/1538-7445.AM2013-4468
Published: 15 April 2013
View article titled, Abstract 4468: Cripto-1 elicits innate resistance to EGFR inhibitors in non-small cell lung cancer harboring EGFR-sensitizing mutations.
Journal Articles

Abstract 2014: Gene expression profiling identifies characteristic oncogenetic pathways in age-related Epstein-Barr virus (EBV)-positive B-cell lymphoproliferative disorders.

Harumi Kato, Kazuhito Yamamoto, Kennosuke Karube, Jun Takizawa, Shinobu Tsuzuki, Yasushi Yatabe, Teru Kanda, Miyuki Katayama, Yukiyasu Ozawa, Kenji Ishitsuka, Masataka Okamoto, Tomohiro Kinoshita, Koichi Oshima, Shigeo Nakamura, Yasuo Morishima, Masao Seto
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2014.
https://doi.org/10.1158/1538-7445.AM2013-2014
Published: 15 April 2013
View article titled, Abstract 2014: Gene expression profiling identifies characteristic oncogenetic pathways in age-related Epstein-Barr virus (EBV)-positive B-cell lymphoproliferative disorders.
Journal Articles

Abstract 1209: Detection of EGFR T790M mutation in non-small-cell lung cancer patients using colony hybridization assay

Yoshihiko Fujita, Kenichi Suda, Hideharu Kimura, Kazuko Matsumoto, Tokuzo Arao, Tomoyuki Nagai, Hidetoshi Hayashi, Kazuyuki Furuta, Hiroaki Kato, Nagahiro Saijo, Yasushi Yatabe, Tetsuya Mitsudomi, kazuto Nishio
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1209.
https://doi.org/10.1158/1538-7445.AM2012-1209
Published: 15 April 2012
View article titled, Abstract 1209: Detection of EGFR T790M mutation in non-small-cell lung cancer patients using colony hybridization assay
Journal Articles

Abstract 3082: TGF-β synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression

Makiko Fujii, Takeshi Toyoda, Hayao Nakanishi, Yasushi Yatabe, Ayuko Sato, Yasue Matsudaira, Hidemi Ito, Hideki Murakami, Yutaka Kondo, Eisaku Kondo, Tohru Tsujimura, Toyoaki Hida, Hirotaka Osada, Yoshitaka Sekido
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3082.
https://doi.org/10.1158/1538-7445.AM2012-3082
Published: 15 April 2012
View article titled, Abstract 3082: TGF-β synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression
Journal Articles

Abstract 1911: A common BIM polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

S. Tiong Ong, King Pan Ng, Axel M. Hillmer, Charles T.H. Chuah, Wen Chun Juan, Tun-Kiat Ko, Audrey S.M. Teo, Pramila N. Ariyaratne, Naoto Takahashi, Kenichi Sawada, Yao Fei, Wah Heng Lee, John W.J. Huang, John C. Allen, Xing Yi Woo, Niranjan Nagarajan, Vikrant Kumar, Anbupalam Thalamuthu, Wan Ting Poh, Li Yi Yang, Liang Piu Koh, Veera S. Nadarajan, Wee Joo Chng, Hein Than, Lay Cheng Lim, Yeow Tee Goh, Sheila Soh, Shenli Zhang, Dianne Poh, Patrick Tan, Ju-Ee Seet, Mei-Kim Ang, Noan-Minh Chau, Quan-Sing Ng, Daniel S.W. Tan, Markus M. Nöthen, Tien Y. Wong, Atif Shahab, Xiaoan Ruan, Valère Cacheux-Rataboul, Wing-Kin Sung, Manabu Soda, Kazutoshi Isobe, Eng Huat Tan, Yasushi Yatabe, Hiroyuki Mano, Ross A. Soo, Tan Min Chin, Wan-Teck Lim, Yijun Ruan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1911.
https://doi.org/10.1158/1538-7445.AM2012-1911
Published: 15 April 2012
View article titled, Abstract 1911: A common BIM polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
Journal Articles

miR-375 Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer

Eri Nishikawa, Hirotaka Osada, Yasumasa Okazaki, Chinatsu Arima, Shuta Tomida, Yoshio Tatematsu, Ayumu Taguchi, Yukako Shimada, Kiyoshi Yanagisawa, Yasushi Yatabe, Shinya Toyokuni, Yoshitaka Sekido, Takashi Takahashi
Journal: Cancer Research
Cancer Res (2011) 71 (19): 6165–6173.
https://doi.org/10.1158/0008-5472.CAN-11-1020
Published: 29 September 2011
View article titled, <em>miR-375</em> Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer
Open the PDF for <em>miR-375</em> Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1120: Role and relevance of TrkB mutations and expression in non-small cell lung cancer

Taishi Harada, Yisong Wang, Yasushi Yatabe, Masafumi Takeshita, Takaomi Koga, Tokujiro Yano, Giuseppe Giaccone
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1120.
https://doi.org/10.1158/1538-7445.AM2011-1120
Published: 15 April 2011
View article titled, Abstract 1120: Role and relevance of TrkB mutations and expression in non-small cell lung cancer
Journal Articles

Abstract 718: Acquired epithelial-mesenchymal transition like feature in an EGFR-mutant lung cancer cell line with acquired resistance to erlotinib

Kenichi Suda, Kenji Tomizawa, Hirotaka Osada, Yoshitaka Sekido, Yasushi Yatabe, Tetsuya Mitsudomi
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 718.
https://doi.org/10.1158/1538-7445.AM2011-718
Published: 15 April 2011
View article titled, Abstract 718: Acquired epithelial-mesenchymal transition like feature in an <em>EGFR</em>-mutant lung cancer cell line with acquired resistance to erlotinib
Journal Articles

Novel Metastasis-Related Gene CIM Functions in the Regulation of Multiple Cellular Stress–Response Pathways

Kiyoshi Yanagisawa, Hiroyuki Konishi, Chinatsu Arima, Shuta Tomida, Toshiyuki Takeuchi, Yukako Shimada, Yasushi Yatabe, Tetsuya Mitsudomi, Hirotaka Osada, Takashi Takahashi
Journal: Cancer Research
Cancer Res (2010) 70 (23): 9949–9958.
https://doi.org/10.1158/0008-5472.CAN-10-1055
Published: 06 December 2010
View article titled, Novel Metastasis-Related Gene CIM Functions in the Regulation of Multiple Cellular Stress–Response Pathways
Open the PDF for Novel Metastasis-Related Gene CIM Functions in the Regulation of Multiple Cellular Stress–Response Pathways in another window
Includes: Supplementary data
Journal Articles

Regulation of DNA Polymerase POLD4 Influences Genomic Instability in Lung Cancer

Qin Miao Huang, Shuta Tomida, Yuji Masuda, Chinatsu Arima, Ke Cao, Taka-aki Kasahara, Hirotaka Osada, Yasushi Yatabe, Tomohiro Akashi, Kenji Kamiya, Takashi Takahashi, Motoshi Suzuki
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8407–8416.
https://doi.org/10.1158/0008-5472.CAN-10-0784
Published: 31 October 2010
View article titled, Regulation of DNA Polymerase POLD4 Influences Genomic Instability in Lung Cancer
Open the PDF for Regulation of DNA Polymerase POLD4 Influences Genomic Instability in Lung Cancer in another window
Includes: Supplementary data