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Journal Articles

Abstract PO2-20-08: Metastatic Lung Cancer Masquerading as Metaplastic Breast Cancer

Tanmayi Pai, Marte Wasserman, Jason Lewis, Miglena Komforti, James Jakub, Augustine Lee, Yanyan Lou, Pooja Advani, Rohit Rao
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-20-08.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-20-08
Published: 02 May 2024
View article titled, Abstract PO2-20-08: Metastatic Lung Cancer Masquerading as Metaplastic Breast Cancer
Journal Articles

Abstract 1208: Plasma proteomics-based models for predicting therapeutic benefit and immune-related adverse events in non-small cell lung cancer patients treated with immunotherapy

Michal Harel, Petros Christopoulos, Igor Puzanov, Jair Bar, Iris Kamer, Niels Reinmuth, Ina Koch, Mor Moskovitz, Adva Levy-Barda, Alona Zer, Michal Lotem, David Farrugia, Rivka Katzenelson, Gillian Price, Abed Agbarya, Helen Cheley, Adam Hassani, Mahmoud Abu-Amna, Tom Geldart, Anirban Chatterjee, Andreas Polychronis, Maya Gottfried, Yanyan Lou, Tatiana Harkovsky, Alison Brewster, Ido Wolf, Ella Tepper, Ben Yellin, Itamar Sela, Coren Lahav, Yehonatan Elon, Raya Leibowitz, Adam P. Dicker, Young Kwang Chae, Ryan J. Sullivan, David Carbone, David Gandara, Jarushka Naidoo
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1208.
https://doi.org/10.1158/1538-7445.AM2024-1208
Published: 22 March 2024
View article titled, Abstract 1208: Plasma proteomics-based models for predicting therapeutic benefit and immune-related adverse events in non-small cell lung cancer patients treated with immunotherapy
Journal Articles

Abstract 2159: A pretreatment blood-based proteomic biomarker for enhanced decision-making in non-small cell lung cancer

Michal Harel, Petros Christopoulos, Coren Lahav, Itamar Sela, Nili Dahan, Niels Reinmuth, Ina Koch, Alona Zer, Mor Moskovitz, Adva Levy-Barda, Michal Lotem, Hovav Nechushtan, Rivka Katzenelson, Abed Agbarya, Mahmoud Abu-Amna, Maya Gottfried, Ido Wolf, Ella Tepper, Yanyan Lou, Raya Leibowitz, Adam P. Dicker, David Gandara, David P. Carbone
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2159.
https://doi.org/10.1158/1538-7445.AM2023-2159
Published: 04 April 2023
View article titled, Abstract 2159: A pretreatment blood-based proteomic biomarker for enhanced decision-making in non-small cell lung cancer
Journal Articles

Abstract CT191: Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC

Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schröeder, Kevin Chin, Michael Shafique, Thaddeus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E. Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, Maurice Zauderer
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT191.
https://doi.org/10.1158/1538-7445.AM2020-CT191
Published: 15 August 2020
View article titled, Abstract CT191: Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC
Journal Articles

Abstract 4230: Influence of sociodemographic factors on treatment decisions in lung cancer

Narjust Duma, Urshila Durani, Ryan Frank, Jonas Paludo, Gustavo Westin, Yanyan Lou, Leventakos Konstantinos, Julian Molina, Ronald Go, Aaron Mansfield, Sikander Ailawadhi, Alex Adjei
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4230.
https://doi.org/10.1158/1538-7445.AM2018-4230
Published: 01 July 2018
View article titled, Abstract 4230: Influence of sociodemographic factors on treatment decisions in lung cancer
Journal Articles

Abstract 628: Neoantigens predicted by clonal mutation analysis in lung adenocarcinoma patients

Dapeng Zhou, Weijing Cai, Deng Pan, Tan Wen Ling, Jiaqian Wang, Caichun Zhou, Yanyan Lou
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 628.
https://doi.org/10.1158/1538-7445.AM2017-628
Published: 01 July 2017
View article titled, Abstract 628: Neoantigens predicted by clonal mutation analysis in lung adenocarcinoma patients
Journal Articles

Abstract 4137: Loss of LKB1 mediates an immune inert phenotype in human lung adenocarcinoma

Warren L. Denning, Ferdinandos Skoulidis, Li Shen, Vassiliki Papadimitrakopoulou, Lixia Diao, Yanyan Lou, Lauren A. Byers, Jing Wang, Jaime R. Canales, Ignacio I. Wistuba, John Weinstein, Don L. Gibbons, John V. Heymach
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4137.
https://doi.org/10.1158/1538-7445.AM2016-4137
Published: 15 July 2016
View article titled, Abstract 4137: Loss of LKB1 mediates an immune inert phenotype in human lung adenocarcinoma
Journal Articles

Abstract A05: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis

Limo Chen, Yanyan Lou, John Heymach, Ignacio Wistuba, Stephen Ullrich, Xiao-Feng Qin, Don Gibbons
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): A05.
https://doi.org/10.1158/1538-7445.TUMMET15-A05
Published: 26 May 2016
View article titled, Abstract A05: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis
Journal Articles

Abstract PR01: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis

Limo Chen, Yanyan Lou, John Heymach, Ignacio Wistuba, Stephen Ullrich, Xiao-Feng Qin, Don Gibbons
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): PR01.
https://doi.org/10.1158/1538-7445.TUMMET15-PR01
Published: 26 May 2016
View article titled, Abstract PR01: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis
Journal Articles

Abstract 3364: Epithelial-mesenchymal transition is associated with a profound inflammatory tumor microenvironment in lung adenocarcinoma

Yanyan Lou, Lixia Diao, Parra Cuentas Edwin Roger, Warren L. Denning, Limo Chen, Youhong Fan, Jaime Rodriguez, Lauren Byers, Jing Wang, Vassiliki Papadimitrakopoulou, Behrens Carmen, Ignacio I. Wistuba, Patrick Hwu, John V. Heymach, Don L. Gibbons
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3364.
https://doi.org/10.1158/1538-7445.AM2015-3364
Published: 01 August 2015
View article titled, Abstract 3364: Epithelial-mesenchymal transition is associated with a profound inflammatory tumor microenvironment in lung adenocarcinoma
Journal Articles

Abstract 456: Defined co-mutation subgroups of KRAS-mutated NSCLC display distinct immune profiles

Warren L. Denning, Lixia Diao, Ferdinandos Skoulidis, Yanyan Lou, Lauren Byers, Jing Wang, John Weinstein, Don Gibbons, John Heymach
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 456.
https://doi.org/10.1158/1538-7445.AM2015-456
Published: 01 August 2015
View article titled, Abstract 456: Defined co-mutation subgroups of KRAS-mutated NSCLC display distinct immune profiles
Journal Articles

Abstract 4256: High programmed cell death ligand 1 expression and low immune infiltrate score correlate with worse outcome in patients with lung adenocarcinoma

Edwin R. Parra, Carmen Behrens, Jaime Rodriguez-Canales, Heather Lin, Barbara Mino, Jorge Blando, Yanyan Lou, Don L. Gibbons, John V. Heymach, Stephen G. Swisher, Annikka Weissferdt, Neda Kahlor, Julie Izzo, J. Jack Lee, Humam Kadara, Cesar Moran, Ignacio Wistuba
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4256.
https://doi.org/10.1158/1538-7445.AM2015-4256
Published: 01 August 2015
View article titled, Abstract 4256: High programmed cell death ligand 1 expression and low immune infiltrate score correlate with worse outcome in patients with lung adenocarcinoma
Journal Articles

PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines

Weiyi Peng, Chengwen Liu, Chunyu Xu, Yanyan Lou, Jieqing Chen, Yan Yang, Hideo Yagita, Willem W. Overwijk, Gregory Lizée, Laszlo Radvanyi, Patrick Hwu
Journal: Cancer Research
Cancer Res (2012) 72 (20): 5209–5218.
https://doi.org/10.1158/0008-5472.CAN-12-1187
Published: 14 October 2012
View article titled, PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines
Open the PDF for PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines in another window
Includes: Supplementary data
Journal Articles

Abstract 1580: LL-37-mediates tumor antigen-specific-T cell expansion and tumor regression

Manisha Singh, Chengwen Liu, Yanyan Lou, Josh Gregorio, Curdin Conrad, Patrick Hwu, Willem W. Overwijk, Michel Gilliet
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1580.
https://doi.org/10.1158/1538-7445.AM2012-1580
Published: 15 April 2012
View article titled, Abstract 1580: LL-37-mediates tumor antigen-specific-T cell expansion and tumor regression
Journal Articles

Abstract 4385: PD-1 blockade enhances T-cell migration to tumor through induction of IFN-γ inducible chemokines

Weiyi Peng, Chenwen Liu, Chunyu Xu, Jieqin Chen, Yanyan Lou, Willem Overwijk, Gregory Lizée, Hideo Yagita, Patrick Hwu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4385.
https://doi.org/10.1158/1538-7445.AM2012-4385
Published: 15 April 2012
View article titled, Abstract 4385: PD-1 blockade enhances T-cell migration to tumor through induction of IFN-γ inducible chemokines
Journal Articles

Abstract 5396: Interferon-α receptor dependent and independent inhibition of type I interferon production in plasmacytoid dendritic cells from mice and melanoma patients

Xue-Fei Huang, Alexander Gelbard, Haiyan S. Li, Tania G. Rodríguez-Cruz, Yanyan Lou, Chengwen Liu, Yared Hailemichael, Vashisht G Yennu Nanda, Michael A. Davies, Yong-Jun Liu, Stephanie S. Watowich, Willem W. Overwijk
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5396.
https://doi.org/10.1158/1538-7445.AM2012-5396
Published: 15 April 2012
View article titled, Abstract 5396: Interferon-α receptor dependent and independent inhibition of type I interferon production in plasmacytoid dendritic cells from mice and melanoma patients
Journal Articles

Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific immune responses

Yanyan Lou, Chengwen Liu, Grace Kim, Yong-Jun Liu, Gang Wang, Patrick Hwu
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 741.
Published: 15 April 2006
View article titled, Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific immune responses
Journal Articles

Dendritic Cells Strongly Boost the Antitumor Activity of Adoptively Transferred T Cells In vivo

Yanyan Lou, Gang Wang, Gregory Lizée, Grace J. Kim, Steven E. Finkelstein, Chiguang Feng, Nicholas P. Restifo, Patrick Hwu
Journal: Cancer Research
Cancer Res (2004) 64 (18): 6783–6790.
https://doi.org/10.1158/0008-5472.CAN-04-1621
Published: 16 September 2004
View article titled, Dendritic Cells Strongly Boost the Antitumor Activity of Adoptively Transferred T Cells <em>In vivo</em>
Open the PDF for Dendritic Cells Strongly Boost the Antitumor Activity of Adoptively Transferred T Cells <em>In vivo</em> in another window
Journal Articles

In vivo antitumor activity of interleukin-21.

Gang Wang, Mary Tschoi, Rosanne Spolski, Yanyan Lou, Katsutoshi Ozaki, Chiguang Feng, Grace Kim, Warren Leonard, Patrick Hwu
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 572.
Published: 01 April 2004
View article titled, <em>In vivo</em> antitumor activity of interleukin-21.
Journal Articles

In Vivo Antitumor Activity of Interleukin 21 Mediated by Natural Killer Cells

Gang Wang, Mary Tschoi, Rosanne Spolski, Yanyan Lou, Katsutoshi Ozaki, Chiguang Feng, Grace Kim, Warren J. Leonard, Patrick Hwu
Journal: Cancer Research
Cancer Res (2003) 63 (24): 9016–9022.
Published: 24 December 2003
View article titled, <em>In Vivo</em> Antitumor Activity of Interleukin 21 Mediated by Natural Killer Cells
Open the PDF for <em>In Vivo</em> Antitumor Activity of Interleukin 21 Mediated by Natural Killer Cells in another window