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Yann Cormerais
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Journal Articles

De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma

Open Access
Manon Teisseire, Umakant Sahu, Julien Parola, Meng-Chen Tsai, Valérie Vial, Jérôme Durivault, Renaud Grépin, Yann Cormerais, Clément Molina, Arthur Gouraud, Gilles Pagès, Issam Ben-Sahra, Sandy Giuliano
Journal: Cancer Research
Cancer Res (2025) 85 (10): 1857–1873.
https://doi.org/10.1158/0008-5472.CAN-24-1393
Published: 15 May 2025
View articletitled, De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma
Open the PDF for De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses

Free
Boutaina Daher, Scott K. Parks, Jerome Durivault, Yann Cormerais, Hanane Baidarjad, Eric Tambutte, Jacques Pouysségur, Milica Vučetić
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (15): 3877–3890.
https://doi.org/10.1158/0008-5472.CAN-18-3855
Published: 01 August 2019
View articletitled, Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
Open the PDF for Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses in another window
Includes: Supplementary data
Journal Articles

Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth

Free
Yann Cormerais, Sandy Giuliano, Renaud LeFloch, Benoît Front, Jerome Durivault, Eric Tambutté, Pierre-André Massard, Laura Rodriguez de la Ballina, Hitoshi Endou, Michael F. Wempe, Manuel Palacin, Scott K. Parks, Jacques Pouyssegur
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (15): 4481–4492.
https://doi.org/10.1158/0008-5472.CAN-15-3376
Published: 31 July 2016
View articletitled, Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Open the PDF for Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth in another window
Includes: Supplementary data