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Journal Articles

Abstract 6741: AT65474, a highly selective anti-CLDN6 ADC with a proprietary payload

Free
Chen Zhong, Yin Wen Cheng, You Xue Wu, Xi Yun Zhang, Rui Yang Zhao, Qian Wang, Ping Du, Shao Jun Liu, Bin Zou
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6741.
https://doi.org/10.1158/1538-7445.AM2025-6741
Published: 21 April 2025
View articletitled, Abstract 6741: AT65474, a highly selective anti-CLDN6 ADC with a proprietary payload
Journal Articles

Abstract 3941: CRISPR screen of human stem cell derived MYC-driven medulloblastoma tumors reveal the mitochondria as a vulnerability

Free
Kenya Pleitez Valle, Miriam Velez, Yang Zhao, Bo Cheng, Sophia Estrada, Linwei Li, Tom O'Loughlin, Balaraman Kalyanaraman, Ming You, Luke A. Gilbert, David M. Hockenbery, David B. Shackelford, Peter J. Mullen, Miller Huang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3941.
https://doi.org/10.1158/1538-7445.AM2025-3941
Published: 21 April 2025
View articletitled, Abstract 3941: CRISPR screen of human stem cell derived MYC-driven medulloblastoma tumors reveal the mitochondria as a vulnerability
Journal Articles

Abstract 4164: Hybrid photoacoustic imaging and fast ultrasound localization microscopy to probe the tumor microenvironment

Free
Shensheng Zhao, Sayantani Basu, Roy H. Campbell, Yang Zhao, Yun-Sheng Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4164.
https://doi.org/10.1158/1538-7445.AM2024-4164
Published: 22 March 2024
View articletitled, Abstract 4164: Hybrid photoacoustic imaging and fast ultrasound localization microscopy to probe the tumor microenvironment
Journal Articles

Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer

Free
Chrissy O'Hersey, Yang Zhao, Thomas R. Pisanic, Tian-Li Wang, Ie-Ming Shih, Tza-Huei Jeff Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7003.
https://doi.org/10.1158/1538-7445.AM2024-7003
Published: 22 March 2024
View articletitled, Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer
Journal Articles

Abstract 6510: REM-DREAMing: Low-cost digital microfluidic analysis of DNA methylation heterogeneity for enhanced, liquid biopsy-based detection of early-stage lung cancer

Free
Yang Zhao, Christine M. O’Keefe, James G. Herman, Thomas R. Pisanic, Tza-Huei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6510.
https://doi.org/10.1158/1538-7445.AM2023-6510
Published: 04 April 2023
View articletitled, Abstract 6510: REM-DREAMing: Low-cost digital microfluidic analysis of DNA methylation heterogeneity for enhanced, liquid biopsy-based detection of early-stage lung cancer
Journal Articles

Abstract 5007: Absence of mammary tissue-resident macrophages is associated with reduced breast cancer susceptibility mediated by the cancer-associated 8q24 gene desert

Free
Bart M. Smits, Anna I. Rissman, Lauren Shunkwiler, Collin Homer-Bouthiette, Yang Zhao, Benjamine van Peel, Jennifer Schulte, Robert Wilson, Adam C. Soloff
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5007.
https://doi.org/10.1158/1538-7445.AM2018-5007
Published: 01 July 2018
View articletitled, Abstract 5007: Absence of mammary tissue-resident macrophages is associated with reduced breast cancer susceptibility mediated by the cancer-associated 8q24 gene desert
Journal Articles

Abstract 610: Dynamic immune landscape of the peripheral blood mononuclear cells from recurrent hepatocellular carcinoma patients undergoing radiofrequency ablation treatment

Free
Dexi Chen, Yang Zhao, Yabo Ouyang, Kai Liu, Wei Rao, Feili Wei, Xiaoni Liu, Ying Shi, Shanshan Wang, Lijun Pang, Luxin Qiao, Yunjin Zang, Xiaoming Yin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 610.
https://doi.org/10.1158/1538-7445.AM2018-610
Published: 01 July 2018
View articletitled, Abstract 610: Dynamic immune landscape of the peripheral blood mononuclear cells from recurrent hepatocellular carcinoma patients undergoing radiofrequency ablation treatment
Journal Articles

Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer

Free
Jason. P.W. Carey, Cansu Karakas, Tuyen Bui, Xian Chen, Smruthi Vijayaraghavan, Yang Zhao, Jing Wang, Keith Mikule, Jennifer K. Litton, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2018) 78 (3): 742–757.
https://doi.org/10.1158/0008-5472.CAN-17-1494
Published: 31 January 2018
View articletitled, Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer
Open the PDF for Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Chemotherapy-Induced Macrophage Infiltration into Tumors Enhances Nanographene-Based Photodynamic Therapy

Free
Yang Zhao, Chenran Zhang, Liquan Gao, Xinhe Yu, Jianhao Lai, Dehua Lu, Rui Bao, Yanpu Wang, Bing Jia, Fan Wang, Zhaofei Liu
Journal: Cancer Research
Cancer Res (2017) 77 (21): 6021–6032.
https://doi.org/10.1158/0008-5472.CAN-17-1655
Published: 31 October 2017
View articletitled, Chemotherapy-Induced Macrophage Infiltration into Tumors Enhances Nanographene-Based Photodynamic Therapy
Open the PDF for Chemotherapy-Induced Macrophage Infiltration into Tumors Enhances Nanographene-Based Photodynamic Therapy in another window
Includes: Supplementary data
Journal Articles

Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell–Mediated Immunotherapy

Free
Yang Zhao, Ka Ka Ting, Jia Li, Victoria C. Cogger, Jinbiao Chen, Anna Johansson-Percival, Shin Foong Ngiow, Jeff Holst, Georges Grau, Shom Goel, Thorleif Muller, Elisabetta Dejana, Geoff McCaughan, Mark J. Smyth, Ruth Ganss, Mathew A. Vadas, Jennifer R. Gamble
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4434–4447.
https://doi.org/10.1158/0008-5472.CAN-16-3129
Published: 14 August 2017
View articletitled, Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell–Mediated Immunotherapy
Open the PDF for Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell–Mediated Immunotherapy in another window
Includes: Supplementary data
Journal Articles

β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q)

Free
Liping Li, Yue Sheng, Wenshu Li, Chao Hu, Nupur Mittal, Kaoru Tohyama, Amber Seba, You-Yang Zhao, Howard Ozer, Tongyu Zhu, Zhijian Qian
Journal: Cancer Research
Cancer Res (2017) 77 (15): 4116–4126.
https://doi.org/10.1158/0008-5472.CAN-17-0202
Published: 01 August 2017
View articletitled, β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q)
Open the PDF for β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q) in another window
Includes: Supplementary data
Journal Articles

Abstract 1115: Serum miR152 as a novel prognostic biomarker and potential tumor suppressor for early stage non-small cell lung cancer

Free
Taro Oba, Yuanqing Ye, Liren Zhang, Jing Lin, Emanuela Gentile, Jing Wang, Yang Zhao, Jiang Gu, Ignacio Wistuba, Jack A. Roth, Xifeng Wu, Lin Ji
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1115.
https://doi.org/10.1158/1538-7445.AM2016-1115
Published: 15 July 2016
View articletitled, Abstract 1115: Serum miR152 as a novel prognostic biomarker and potential tumor suppressor for early stage non-small cell lung cancer
Journal Articles

Abstract LB-134: Sequential validation of blood-based protein biomarker candidates for early-stage pancreatic cancer

Free
Michela Capello, Leonidas E. Bantis, Ghislaine Scelo, Yang Zhao, Dilsher S. Dhillon, Hong Wang, James L. Abbruzzese, Anirban Maitra, Margaret A. Tempero, Randall Brand, Matthew A. Firpo, Sean Mulvihill, Matthew H. Katz, Paul Brennan, Ziding Feng, Samir M. Hanash, Ayumu Taguchi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-134.
https://doi.org/10.1158/1538-7445.AM2016-LB-134
Published: 15 July 2016
View articletitled, Abstract LB-134: Sequential validation of blood-based protein biomarker candidates for early-stage pancreatic cancer
Journal Articles

Abstract 964: Circulating biomarker miRNA-150 promotes tumor cell proliferation and progression by targeting SRC kinase signaling inhibitor 1 (SRCIN1) in non-small cell lung cancer

Free
Jing Lin, Liren Zhang, Yuanqing Ye, Taro Oba, Emanuela Gentile, Emanuela Gentile, Jing Wang, Yang Zhao, Jian Gu, Ignacio Wistuba, Jack A. Roth, Xifeng Wu, Lin Ji
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 964.
https://doi.org/10.1158/1538-7445.AM2016-964
Published: 15 July 2016
View articletitled, Abstract 964: Circulating biomarker miRNA-150 promotes tumor cell proliferation and progression by targeting SRC kinase signaling inhibitor 1 (SRCIN1) in non-small cell lung cancer
Journal Articles

Abstract B20: Development and validation of diagnostic biomarker model for detection of early stage pancreatic cancer

Free
Ayumu Taguchi, Michela Capello, Yang Zhao, Ingrid Babel, Gary Goodman, Margaret A. Tempero, Matthew A. Firpo, Matthew H. Katz, Ziding Feng, Samir Hanash
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B20.
https://doi.org/10.1158/1538-7445.PANCA2014-B20
Published: 30 June 2015
View articletitled, Abstract B20: Development and validation of diagnostic biomarker model for detection of early stage pancreatic cancer
Journal Articles

Abstract 5439: Metabolomic study of EGFR drug resistance mechanisms

Free
Yang Zhao, Bo Tan, Ming-Shang Kuo, Ling Liu, Matthew D. Breyer
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5439.
https://doi.org/10.1158/1538-7445.AM2014-5439
Published: 01 October 2014
View articletitled, Abstract 5439: Metabolomic study of EGFR drug resistance mechanisms
Journal Articles

Abstract 58: Highly tractable stem cell-driven mouse model of colonic neoplasia with features of familial adenomatous polyposis

Free
Anne E. Powell, Gregory Vlacich, Zhen-Yang Zhao, Eliot McKinley, Rebekah Karns, Mary Kay Washington, Henry Charles Manning, Bruce Aronow, Robert Coffey
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 58.
https://doi.org/10.1158/1538-7445.AM2014-58
Published: 01 October 2014
View articletitled, Abstract 58: Highly tractable stem cell-driven mouse model of colonic neoplasia with features of familial adenomatous polyposis
Journal Articles

Abstract 1866: Stable isotope resolved metabolomics of colorectal cancer cells treated with inhibitor of monocarboxylate transporter-1.

Free
Bo Tan, Ming-Shang Kuo, Matthew D. Breyer, Ling Liu, Yang Zhao
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1866.
https://doi.org/10.1158/1538-7445.AM2013-1866
Published: 15 April 2013
View articletitled, Abstract 1866: Stable isotope resolved metabolomics of colorectal cancer cells treated with inhibitor of monocarboxylate transporter-1.
Journal Articles

Abstract 2547: Targeted sequencing of 5p15 locus defined by non-small cell lung cancer (NSCLC) GWAS using next-generation sequencing.

Free
Zhaoxi Wang, Yang Zhao, Li Su, Seunggeun Lee, Xihong Lin, David C. Christiani
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2547.
https://doi.org/10.1158/1538-7445.AM2013-2547
Published: 15 April 2013
View articletitled, Abstract 2547: Targeted sequencing of 5p15 locus defined by non-small cell lung cancer (NSCLC) GWAS using next-generation sequencing.
Journal Articles

Abstract 1391: Cellular and molecular bases of susceptibility to estrogen-induced mammary cancer in the rat.

Free
Lina Ding, Yang Zhao, Christopher Warren, James Shull
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1391.
https://doi.org/10.1158/1538-7445.AM2013-1391
Published: 15 April 2013
View articletitled, Abstract 1391: Cellular and molecular bases of susceptibility to estrogen-induced mammary cancer in the rat.