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Journal Articles

Abstract 5068: Spatial architecture and epigenetic programs in IDH-mutant and wildtype glioma

Jingxian Liu, Song Cao, Wagma Caravan, Xiangwei Fang, Preet Lal, Andrew Houston, Yuting Zhao, Faria Anjum Simin, Michael C. Jin, Jennifer Ponce, Robert Fulton, Michael Heinz, Yang Li, Sonika Dahiya, Dimitrios Mathios, Tao Liu, Albert H. Kim, Milan G. Chheda, Li Ding

Cancer Res (2025) 85 (8_Supplement_1): 5068.

https://doi.org/10.1158/1538-7445.AM2025-5068

Published: 21 April 2025

View article titled, Abstract 5068: Spatial architecture and epigenetic programs in IDH-mutant and wildtype glioma

Journal Articles

Abstract 1233: Construction and application of an immune microphysiological model for lung cancer

Jianli Dai, Qianqian Wang, Junhong Li, Yang Li, Wenbo Ma, Qing Zhang, Jingyu Yang, Panglian Xu, Yanmei Zhang

Cancer Res (2025) 85 (8_Supplement_1): 1233.

https://doi.org/10.1158/1538-7445.AM2025-1233

Published: 21 April 2025

View article titled, Abstract 1233: Construction and application of an immune microphysiological model for lung cancer

Journal Articles

Abstract 3510: A 2+1 format MUC16 targeting T cell engager induces MUC16-dependent T cell activity and superior anti-tumor efficacy

Jinyang Li, Yang Li, Nan Gao, Yi Wang, Mengqiang Di, Min Wu, Yiyi Li, Ran Xue, Shiyu Hao, Weiwei Wu, Xiguang Zhang, Li Li, Shuaixiang Zhou, Huizhong Xiong

Cancer Res (2025) 85 (8_Supplement_1): 3510.

https://doi.org/10.1158/1538-7445.AM2025-3510

Published: 21 April 2025

View article titled, Abstract 3510: A 2+1 format MUC16 targeting T cell engager induces MUC16-dependent T cell activity and superior anti-tumor efficacy

Journal Articles

Abstract 6769: Zanubrutinib (zanu) overcomes BTK V416L resistance in B cell lymphoma models

Haitao Wang, Xiaoyu Feng, Jinhong Ren, Lanyue Bai, Lin Li, Chao Cui, Lei Shi, Yang Li, Yangyang Wang, Jessica Li, Teiko Sumiyoshi, Yangbo Yue, Wei Jin, Zhirong Shen

Cancer Res (2025) 85 (8_Supplement_1): 6769.

https://doi.org/10.1158/1538-7445.AM2025-6769

Published: 21 April 2025

View article titled, Abstract 6769: Zanubrutinib (zanu) overcomes BTK V416L resistance in B cell lymphoma models

Journal Articles

Abstract 5432: Restoring mitochondrial quantity and quality to reverse Warburg effect and drive tumor differentiation

Cancer Res (2025) 85 (8_Supplement_1): 5432.

https://doi.org/10.1158/1538-7445.AM2025-5432

Published: 21 April 2025

View article titled, Abstract 5432: Restoring mitochondrial quantity and quality to reverse Warburg effect and drive tumor differentiation

Journal Articles

Abstract 5600: BTK T474I with enhanced kinase activity confers growth advantage over BTK-L528W with kinase deficiency in B malignant cells

Wenjing Zhang, Xinxin Zhu, Qiming Zhou, Jiayun Song, Yang Li, Bo Li, Ming Jiang, Xiaoliang Cheng, Teiko Sumiyoshi, Yangbo Yue, Wei Jin, Zhirong Shen

Cancer Res (2025) 85 (8_Supplement_1): 5600.

https://doi.org/10.1158/1538-7445.AM2025-5600

Published: 21 April 2025

View article titled, Abstract 5600: BTK T474I with enhanced kinase activity confers growth advantage over BTK-L528W with kinase deficiency in B malignant cells

Journal Articles

Abstract 4374: Discovery of a highly potent and efficacious SOS1 inhibitor targeting KRAS-driven cancers

Yang Li, Yang Zang, Wenbing Hu, Yuan Zhou, Lifei Liu, Xuejun Zhang, Shaohua Chang

Cancer Res (2025) 85 (8_Supplement_1): 4374.

https://doi.org/10.1158/1538-7445.AM2025-4374

Published: 21 April 2025

View article titled, Abstract 4374: Discovery of a highly potent and efficacious SOS1 inhibitor targeting KRAS-driven cancers

Journal Articles

Inhibition of JNK Signaling Overcomes Cancer-Associated Fibroblast-Mediated Immunosuppression and Enhances the Efficacy of Immunotherapy in Bladder Cancer

Chengying Cui, Haojie Zhang, Congcong Yang, Mingwei Yin, Xinkun Teng, Miaomiao Yang, Dejie Kong, Jinzhi Zhang, Weidong Peng, Zhimin Chu, Jingjing Wang, Yating Sun, Liping Kang, Bin Lyu, Qian Gao, Mingqing Wu, Yongqiang Wang, Yang Li

Cancer Res (2024) 84 (24): 4199–4213.

https://doi.org/10.1158/0008-5472.CAN-24-0940

Published: 16 December 2024

View article titled, Inhibition of JNK Signaling Overcomes Cancer-Associated Fibroblast-Mediated Immunosuppression and Enhances the Efficacy of Immunotherapy in Bladder Cancer

Includes: Supplementary data

Journal Articles

Abstract 3371: PRMT blockade induces defective DNA replication stress response via ATR suppression and synergizes with PARP inhibition

Cancer Res (2024) 84 (6_Supplement): 3371.

https://doi.org/10.1158/1538-7445.AM2024-3371

Published: 22 March 2024

View article titled, Abstract 3371: PRMT blockade induces defective DNA replication stress response via ATR suppression and synergizes with PARP inhibition

Journal Articles

Abstract 3344: Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA binding proteins

Babita Kaundal, Daniel J. McGrail, Yang Li, Roger S. Smith, Bin Feng, Hui Dai, Limei Hu, Briana Dennehey, Sharad Awasthi, Marc L. Mendillo, Anil K. Sood, Gordon B. Mills, Shiaw-Yih Lin, S. Stephen Yi, Nidhi Sahni

Cancer Res (2024) 84 (6_Supplement): 3344.

https://doi.org/10.1158/1538-7445.AM2024-3344

Published: 22 March 2024

View article titled, Abstract 3344: Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA binding proteins

Journal Articles

Abstract 1821: Conessine inhibits cell proliferation, migration and invasion, and induces apoptosis in liver cancer cells

Chia-Yang Li, Yu-Sheng Lin

Cancer Res (2024) 84 (6_Supplement): 1821.

https://doi.org/10.1158/1538-7445.AM2024-1821

Published: 22 March 2024

View article titled, Abstract 1821: Conessine inhibits cell proliferation, migration and invasion, and induces apoptosis in liver cancer cells

Journal Articles

Abstract 5651: Personalized transcriptomic profiling for advanced prostate cancer: Guiding second-generation hormonal drug selection

Li-Hsin Chang, Hao-Han Chang, Xin-Yi Lin, Shu-Chi Wang, Chih-Pin Chuu, Deng-Neng Chen, Shu-Pin Huang, Chia-Yang Li

Cancer Res (2024) 84 (6_Supplement): 5651.

https://doi.org/10.1158/1538-7445.AM2024-5651

Published: 22 March 2024

View article titled, Abstract 5651: Personalized transcriptomic profiling for advanced prostate cancer: Guiding second-generation hormonal drug selection

Journal Articles

Abstract 628: RNA binding protein Matrin3 acts as a tumor suppressor by inhibiting microtubule nucleation

Cancer Res (2024) 84 (6_Supplement): 628.

https://doi.org/10.1158/1538-7445.AM2024-628

Published: 22 March 2024

View article titled, Abstract 628: RNA binding protein Matrin3 acts as a tumor suppressor by inhibiting microtubule nucleation

Journal Articles

Abstract 7477: Isoxanthohumol inhibits LPS-induced inflammatory responses in macrophages

Tzu-Han Kao, Chia-yang Li

Cancer Res (2024) 84 (6_Supplement): 7477.

https://doi.org/10.1158/1538-7445.AM2024-7477

Published: 22 March 2024

View article titled, Abstract 7477: Isoxanthohumol inhibits LPS-induced inflammatory responses in macrophages

Journal Articles

Abstract 7476: Obtusifolin attenuates LPS-induced inflammation and NLRP3 inflammasome activation by suppressing the MAPK/NF-κB signaling pathway and ROS production in BV2 cells

Hsin Yi Lin, Che-Hsin Lee, Chia-Yang Li

Cancer Res (2024) 84 (6_Supplement): 7476.

https://doi.org/10.1158/1538-7445.AM2024-7476

Published: 22 March 2024

View article titled, Abstract 7476: Obtusifolin attenuates LPS-induced inflammation and NLRP3 inflammasome activation by suppressing the MAPK/NF-κB signaling pathway and ROS production in BV2 cells

Journal Articles

Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

Chih-Yi Chen, Yu-Ching Huang, Wen-Hsiu Su, Yi-Ting Liu, Chi-Sheng Chen, Chia-Yang Li, Kun-Che Chang, Chia-Yen Dai, Shu-Chi Wang

Cancer Res (2024) 84 (6_Supplement): 5773.

https://doi.org/10.1158/1538-7445.AM2024-5773

Published: 22 March 2024

View article titled, Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

Journal Articles

Abstract LB182: Targeting arginine methylation for improved therapy in triple negative breast cancer

Yang Li, Daniel J. McGrail, Sharad Awasthi, S. Stephen Yi, Mark T. Bedford, Nidhi Sahni

Cancer Res (2023) 83 (8_Supplement): LB182.

https://doi.org/10.1158/1538-7445.AM2023-LB182

Published: 14 April 2023

View article titled, Abstract LB182: Targeting arginine methylation for improved therapy in triple negative breast cancer

Journal Articles

Abstract 3695: Mitochondrial uncoupling reverses reductive carboxylation in cancer

Haowen Jiang, Clifford Jiajun He, Albert M. Li, Bo He, Yang Li, Jiangbin Ye

Cancer Res (2023) 83 (7_Supplement): 3695.

https://doi.org/10.1158/1538-7445.AM2023-3695

Published: 04 April 2023

View article titled, Abstract 3695: Mitochondrial uncoupling reverses reductive carboxylation in cancer

Journal Articles

Abstract 4847: Investigating the transcriptional regulation by estrogen-related receptor alpha (ERRα) under different metabolic conditions

Brittney A. Hua, Chien-yu Chen, Yang Li, Lina He, Bangyan Stiles, Ielyzaveta Slarve

Cancer Res (2023) 83 (7_Supplement): 4847.

https://doi.org/10.1158/1538-7445.AM2023-4847

Published: 04 April 2023

View article titled, Abstract 4847: Investigating the transcriptional regulation by estrogen-related receptor alpha (ERRα) under different metabolic conditions

Journal Articles

Abstract 5831: CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor associated macrophages

Cho-Hao Lin, Fatemeh Talebian, Yang Li, Jianmin Zhu, Bolin Zhao, Jin-Qing Liu, Sujit Basu, Xueling Pan, Xi Chen, Pearlly Yan, William E. Carson, Gang Xin, Haitao Wen, Ruoning Wang, Zihai Li, Qin Ma, Xue-Feng Bai

Cancer Res (2023) 83 (7_Supplement): 5831.

https://doi.org/10.1158/1538-7445.AM2023-5831

Published: 04 April 2023

View article titled, Abstract 5831: CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor associated macrophages

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Abstract 5068: Spatial architecture and epigenetic programs in IDH-mutant and wildtype glioma

Abstract 1233: Construction and application of an immune microphysiological model for lung cancer

Abstract 3510: A 2+1 format MUC16 targeting T cell engager induces MUC16-dependent T cell activity and superior anti-tumor efficacy

Abstract 6769: Zanubrutinib (zanu) overcomes BTK V416L resistance in B cell lymphoma models

Abstract 5432: Restoring mitochondrial quantity and quality to reverse Warburg effect and drive tumor differentiation

Abstract 5600: BTK T474I with enhanced kinase activity confers growth advantage over BTK-L528W with kinase deficiency in B malignant cells

Abstract 4374: Discovery of a highly potent and efficacious SOS1 inhibitor targeting KRAS-driven cancers

Inhibition of JNK Signaling Overcomes Cancer-Associated Fibroblast-Mediated Immunosuppression and Enhances the Efficacy of Immunotherapy in Bladder Cancer

Abstract 3371: PRMT blockade induces defective DNA replication stress response via ATR suppression and synergizes with PARP inhibition

Abstract 3344: Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA binding proteins

Abstract 1821: Conessine inhibits cell proliferation, migration and invasion, and induces apoptosis in liver cancer cells

Abstract 5651: Personalized transcriptomic profiling for advanced prostate cancer: Guiding second-generation hormonal drug selection

Abstract 628: RNA binding protein Matrin3 acts as a tumor suppressor by inhibiting microtubule nucleation

Abstract 7477: Isoxanthohumol inhibits LPS-induced inflammatory responses in macrophages

Abstract 7476: Obtusifolin attenuates LPS-induced inflammation and NLRP3 inflammasome activation by suppressing the MAPK/NF-κB signaling pathway and ROS production in BV2 cells

Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

Abstract LB182: Targeting arginine methylation for improved therapy in triple negative breast cancer

Abstract 3695: Mitochondrial uncoupling reverses reductive carboxylation in cancer

Abstract 4847: Investigating the transcriptional regulation by estrogen-related receptor alpha (ERRα) under different metabolic conditions

Abstract 5831: CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor associated macrophages

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