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Journal Articles

Abstract CT248: Design and rationale of a first in human (FIH) phase 1/1b study evaluating KIN-2787, a potent and highly selective pan-RAF inhibitor, in adult patients with BRAF- and NRAS-mutation positive solid tumors

Meredith McKean, Cesar A. Perez, Shumei Kato, Alexander I. Spira, Yan Xing, Hao Xie, Michael Millward, Anthony Olszanski, Ken Kobayashi, Nichol Miller, Paul Severson, Betty Tam, Caro Unger
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT248.
https://doi.org/10.1158/1538-7445.AM2022-CT248
Published: 15 June 2022
View article titled, Abstract CT248: Design and rationale of a first in human (FIH) phase 1/1b study evaluating KIN-2787, a potent and highly selective pan-RAF inhibitor, in adult patients with BRAF- and NRAS-mutation positive solid tumors
Journal Articles

Abstract 974: Phase II trial of the Wee1 inhibitor adavosertib in advanced refractory solid tumors with CCNE1 amplification

Siqing Fu, Shuyang Yao, Yuan Yuan, Rebecca A. Previs, Anthony D. Elias, Richard Carvajal, Thomas J. George, Ying Yuan, Yuko Yamamura, Shannon Westin, Yan Xing, Ecaterina E. Ileana Dumbrava, Daniel D. Karp, Sarina A. Piha-Paul, Apostolia M. Tsimberidou, Jordi Rodon, Naoko Takebe, Charles Kunos, Karen Lu, Khanda Keyomarsi, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 974.
https://doi.org/10.1158/1538-7445.AM2021-974
Published: 01 July 2021
View article titled, Abstract 974: Phase II trial of the Wee1 inhibitor adavosertib in advanced refractory solid tumors with CCNE1 amplification
Journal Articles

Abstract 3300: Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors

Dan Zhao, Isa Mambetsariev, Haiqing Li, Chen Chen, Jeremy Fricke, Patricia Fann, Prakash Kulkarni, Yan Xing, Peter Lee, Andrea Bild, Erminia Massarelli, Marianna Koczywas, Karen Reckamp, Ravi Salgia
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3300.
https://doi.org/10.1158/1538-7445.AM2020-3300
Published: 15 August 2020
View article titled, Abstract 3300: Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors
Journal Articles

Abstract 4242: Systematic transcriptome analysis of small cell carcinoma of esophagus suggests a possibility for immunotherapy

Qi Zhao, Yan-xing Chen, Ying-nan Wang, Qi-nian Wu, Hui Sheng, JIa-jia Hu, Yun-xin Lu, Ze-xian Liu, Zhi-xiang Zuo, Feng Wang, Rui-hua Xu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4242.
https://doi.org/10.1158/1538-7445.AM2019-4242
Published: 01 July 2019
View article titled, Abstract 4242: Systematic transcriptome analysis of small cell carcinoma of esophagus suggests a possibility for immunotherapy
Journal Articles

Abstract 2091: PRN1371, an irreversible, covalent inhibitor of FGFR1-4 exhibits sustained pathway inhibition in cancer cell lines

Eleni Venetsanakos, Yan Xing, Natalie Loewenstein, J. Michael Bradshaw, Dane Karr, Jacob LaStant, Philip Nunn, Jin Shu, Abha Bommireddi, Jens Oliver Funk, David M. Goldstein, Stefani Wolff, Ken A. Brameld, Steven G. Gourlay
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2091.
https://doi.org/10.1158/1538-7445.AM2017-2091
Published: 01 July 2017
View article titled, Abstract 2091: PRN1371, an irreversible, covalent inhibitor of FGFR1-4 exhibits sustained pathway inhibition in cancer cell lines
Journal Articles

Abstract 1249: PRN1371, an irreversible, covalent inhibitor of FGFR1, 2, 3 and 4 is highly efficacious in preclinical tumor models

Eleni Venetsanakos, Michael Bradshaw, David M. Goldstein, Kwan Leung, Dane Karr, Yan Xing, Jacob LaStant, Philip Nunn, Jin Shu, Abha Bommireddi, Steven G. Gourlay, Jens Oliver Funk, Ken A. Brameld
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1249.
https://doi.org/10.1158/1538-7445.AM2016-1249
Published: 15 July 2016
View article titled, Abstract 1249: PRN1371, an irreversible, covalent inhibitor of FGFR1, 2, 3 and 4 is highly efficacious in preclinical tumor models
Journal Articles

Abstract 109: Multiple different mutations of same cancer genes in the same tumors from lung adenocarcinoma patients

Yan Xing, Jianjun Zhang, Jun Li, Jianhua Zhang, Alexandria T. Phan, Jenny C. Chang, Andrew Futreal
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 109.
https://doi.org/10.1158/1538-7445.AM2016-109
Published: 15 July 2016
View article titled, Abstract 109: Multiple different mutations of same cancer genes in the same tumors from lung adenocarcinoma patients
Journal Articles

An Integrated Analysis of Heterogeneous Drug Responses in Acute Myeloid Leukemia That Enables the Discovery of Predictive Biomarkers

Weihsu C. Chen, Julie S. Yuan, Yan Xing, Amanda Mitchell, Nathan Mbong, Andreea C. Popescu, Jessica McLeod, Gitte Gerhard, James A. Kennedy, Goce Bogdanoski, Stevan Lauriault, Sofie Perdu, Yulia Merkulova, Mark D. Minden, Donna E. Hogge, Cynthia Guidos, John E. Dick, Jean C.Y. Wang
Journal: Cancer Research
Cancer Res (2016) 76 (5): 1214–1224.
https://doi.org/10.1158/0008-5472.CAN-15-2743
Published: 29 February 2016
View article titled, An Integrated Analysis of Heterogeneous Drug Responses in Acute Myeloid Leukemia That Enables the Discovery of Predictive Biomarkers
Open the PDF for An Integrated Analysis of Heterogeneous Drug Responses in Acute Myeloid Leukemia That Enables the Discovery of Predictive Biomarkers in another window
Includes: Supplementary data
Journal Articles

Abstract 2914: Phosphoproteomic and transcriptional biomarkers predict response to SAR302503, a JAK2 inhibitor, in human acute myeloid leukemia preclinical models

Weihsu Claire Chen, Julie S. Yuan, Nathan Mbong, Andreea C. Popescu, Yan Xing, Gitte Gerhard, Wei Zhang, Yussanne Ma, Richard Moore, Marco Marra, Mark D. Minden, Donna E. Hogge, Cynthia Guidos, John E. Dick, Jean C.Y. Wang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2914.
https://doi.org/10.1158/1538-7445.AM2014-2914
Published: 01 October 2014
View article titled, Abstract 2914: Phosphoproteomic and transcriptional biomarkers predict response to SAR302503, a JAK2 inhibitor, in human acute myeloid leukemia preclinical models
Journal Articles

Abstract 907: Efficacy of SAR302503, a JAK2 inhibitor, in primary human acute myeloid leukemia xenografts.

Weihsu C. Chen, Andreea C. Popescu, Yan Xing, Gitte Gerhard, Julie Yuan, Mark Minden, Cynthia Guidos, Donna E. Hogge, John E. Dick, Jean CY Wang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 907.
https://doi.org/10.1158/1538-7445.AM2013-907
Published: 15 April 2013
View article titled, Abstract 907: Efficacy of SAR302503, a JAK2 inhibitor, in primary human acute myeloid leukemia xenografts.
Journal Articles

Preliminary investigation of lung cancer CTC distribution in patient body circulation

Hui-Qin Guo, Huai-Jie Hao, Ze-Jian Li, Yi-Ming Zhu, Jie Sun, Feng Ge, Shu-Lan Wang, Xiao-Yan Xing, Gioulnar Harvie, Elizabeth Vuong, Jian-Yu Rao, Ross Bremner, Tony Reid, Ping Lin, Jia Xu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3694.
Published: 01 May 2008
View article titled, Preliminary investigation of lung cancer CTC distribution in patient body circulation
Journal Articles

Enrichment and detection of circulating tumor cells in breast cancer patients

Dong-Min Wang, Yin-Hua Liu, Yu-He Liu, Chun-Yu Wang, Hong-Mei Bao, Huai-Jie Hao, Shu-Lan Wang, Yao Zhang, Hai-Bo Yu, Xiao-Yan Xing, Gioulnar Harvie, Elizabeth Vuong, Jian-Yu Rao, Tony Reid, Ping Lin, Jia Xu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3692.
Published: 01 May 2008
View article titled, Enrichment and detection of circulating tumor cells in breast cancer patients
Journal Articles

Detection of circulating tumor cells in newly diagnosed or relapsed lung cancer patients and the significance of CTC enumeration in patient staging

Long-Yun Li, Xiao-Yun Zhou, Huai-Jie Hao, Meng-Zhao Wang, Zi-Jian Guo, Shu-Lan Wang, Xiao-Yan Xing, Gioulnar Harvie, Elizabeth Vuong, Wen-Ge Shi, Meng-Jia Tang, Jian-Yu Rao, Tony Reid, Ross Bremner, Ping Lin, Jia Xu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3691.
Published: 01 May 2008
View article titled, Detection of circulating tumor cells in newly diagnosed or relapsed lung cancer patients and the significance of CTC enumeration in patient staging
Journal Articles

Detection of circulating tumor cell in patients with colorectal cancer and its potential implication

Yuan-jia Chen, Hong-Mei Bao, Chun-Yu Zhou, Xiao-Yan Xing, Gioulnar Harvie, Elizabeth Vuong, Jian-Yu Rao, Tony Reid, Hui-Zhong Qiu, Yi Xiao, Hai-Yan Wu, Mei Mei, Chong-Mei Lu, Ping Lin, Jia Xu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3696.
Published: 01 May 2008
View article titled, Detection of circulating tumor cell in patients with colorectal cancer and its potential implication
Journal Articles

Increased Expression of Germinal Center–Associated Nuclear Protein RNA-Primase Is Associated with Lymphomagenesis

Satoru Fujimura, Yan Xing, Motohiro Takeya, Yasuyuki Yamashita, Koichi Ohshima, Kazuhiko Kuwahara, Nobuo Sakaguchi
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5925–5934.
https://doi.org/10.1158/0008-5472.CAN-04-3259
Published: 01 July 2005
View article titled, Increased Expression of Germinal Center–Associated Nuclear Protein RNA-Primase Is Associated with Lymphomagenesis
Open the PDF for Increased Expression of Germinal Center–Associated Nuclear Protein RNA-Primase Is Associated with Lymphomagenesis in another window
Includes: Supplementary data