1-20 of 25
Yan Shi
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT178: GQ1001: A next generation HER2-targeting ADC that exhibits promising early clinical efficacy with excellent tolerance in a multi-center, Phase Ia study

Charlotte Lemech, Chenfei Zhou, Xianbao Zhan, Yan Shi, Jieqiong Liu, Sarina A Piha-Paul, Gary Richardson, Gang Qin, Paul H. Song, Lili Shi, Yajun Sun, Yi Xia
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT178.
https://doi.org/10.1158/1538-7445.AM2023-CT178
Published: 14 April 2023
View article titled, Abstract CT178: GQ1001: A next generation HER2-targeting ADC that exhibits promising early clinical efficacy with excellent tolerance in a multi-center, Phase Ia study
Journal Articles

Abstract 2702: GQ1001 is a next generation HER2-targeting ADC with excellent druggability, safety and potency

Lei Huang, Lili Shi, Yajun Sun, Cao Lv, Chengcheng Gong, Chong Liu, Jun Yang, Lu Jiang, Jinduo Yuan, Xuesong Li, Mingyu Hu, Xinju Gao, Yu Si, Hui Yang, Yan Shi, Bo Yang, Paul H. Song, Gang Qin, Biyun Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2702.
https://doi.org/10.1158/1538-7445.AM2023-2702
Published: 04 April 2023
View article titled, Abstract 2702: GQ1001 is a next generation HER2-targeting ADC with excellent druggability, safety and potency
Journal Articles

Abstract 1358: Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma

Rong Huang, Gaigai Shen, Yu Ren, Kelin Zheng, Jiayu Wang, Yan Shi, Jiani C. Yin, Lanqun Qin, Guiying Zhang, Mengke Zhao, Xinyu Su, Luqiao Li, Fufeng Wang, Haimeng Tang, Yang Shao, Baorui Liu, Zhengyun Zou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1358.
https://doi.org/10.1158/1538-7445.AM2023-1358
Published: 04 April 2023
View article titled, Abstract 1358: Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma
Journal Articles

Abstract 5766: Pan-cancer analysis revealed characteristics of reversion mutations in homologous recombination repair genes

Jing Li, Xiaoying Wu, Yan Shi, Di Wang, Yedan Chen, Yang Shao
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5766.
https://doi.org/10.1158/1538-7445.AM2022-5766
Published: 15 June 2022
View article titled, Abstract 5766: Pan-cancer analysis revealed characteristics of reversion mutations in homologous recombination repair genes
Journal Articles

Precise Spatiotemporal Interruption of Regulatory T-cell–Mediated CD8+ T-cell Suppression Leads to Tumor Immunity

Xiaoyu Zhou, Shushu Zhao, Yue He, Shuang Geng, Yan Shi, Bin Wang
Journal: Cancer Research
Cancer Res (2019) 79 (3): 585–597.
https://doi.org/10.1158/0008-5472.CAN-18-1250
Published: 01 February 2019
View article titled, Precise Spatiotemporal Interruption of Regulatory T-cell–Mediated CD8<sup>+</sup> T-cell Suppression Leads to Tumor Immunity
Open the PDF for Precise Spatiotemporal Interruption of Regulatory T-cell–Mediated CD8<sup>+</sup> T-cell Suppression Leads to Tumor Immunity in another window
Includes: Supplementary data
Journal Articles

Abstract 4127: Targeting MDM4 in hepatocellular carcinoma to reactivate p53 signaling

Sarah E. Woodfield, Yan Shi, Roma H. Patel, Zhenghu Chen, Aryana M. Ibarra, Sanjeev A. Vasudevan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4127.
https://doi.org/10.1158/1538-7445.AM2017-4127
Published: 01 July 2017
View article titled, Abstract 4127: Targeting MDM4 in hepatocellular carcinoma to reactivate p53 signaling
Journal Articles

Abstract B16: NR5A2 as a potential therapeutic target for hepatoblastoma

Jingling Jin, Roma Patel, Nan Ge Jin, Yan Shi, Wenjing Sun, Jianhua Yang, Jed G. Nuchtern, Sanjeev A. Vasudevan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): B16.
https://doi.org/10.1158/1538-7445.PEDCA15-B16
Published: 04 April 2016
View article titled, Abstract B16: NR5A2 as a potential therapeutic target for hepatoblastoma
Journal Articles

Abstract B29: MDM4 is a major p53 regulator in hepatoblastoma

Yan Shi, Roma Patel, Emporia Hollingsworth, Stephen Sarabia, Jingling Jin, Dolores Lopez-Terrada, Sanjeev Vasudevan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): B29.
https://doi.org/10.1158/1538-7445.PEDCA15-B29
Published: 04 April 2016
View article titled, Abstract B29: MDM4 is a major p53 regulator in hepatoblastoma
Journal Articles

Abstract 1136: Regulation of AMPK by androgen receptor signaling and its role in promoting prostate cancer through the use of autophagy

Yan Shi, Efrosini Tsouko, Alicia M. Blessing, Jayantha Tennakoon, Jenny J. Han, Michael M. Ittmann, Daniel E. Frigo
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1136.
https://doi.org/10.1158/1538-7445.AM2015-1136
Published: 01 August 2015
View article titled, Abstract 1136: Regulation of AMPK by androgen receptor signaling and its role in promoting prostate cancer through the use of autophagy
Journal Articles

Abstract 2734: Veliparib (ABT-888) potentiates the cytotoxic activity of DNA alkylating agents by trapping PARP onto damaged chromatin

Larry Solomon, Todd Hopkins, Yan Shi, Paul Ellis, Cherrie Donawho, Eric F. Johnson, Guowei Fang, David Maag
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2734.
https://doi.org/10.1158/1538-7445.AM2014-2734
Published: 01 October 2014
View article titled, Abstract 2734: Veliparib (ABT-888) potentiates the cytotoxic activity of DNA alkylating agents by trapping PARP onto damaged chromatin
Journal Articles

Abstract 2450: CaMKK2-AMPK signaling facilitates androgen-mediated prostate cancer cell metabolism

Daniel E. Frigo, Yan Shi, Jenny J. Han, Efrosini Tsouko, Michael M. Ittmann
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2450.
https://doi.org/10.1158/1538-7445.AM2014-2450
Published: 01 October 2014
View article titled, Abstract 2450: CaMKK2-AMPK signaling facilitates androgen-mediated prostate cancer cell metabolism
Journal Articles

Abstract 4195: Peroxisome proliferator-activated receptor α is regulated by E2F1-induced miR-19a in a feedback loop in glioma progression

Junxia Zhang, Yan Shi, Yingyi Wang, Wenkang Luan, Yongping You
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4195.
https://doi.org/10.1158/1538-7445.AM2014-4195
Published: 01 October 2014
View article titled, Abstract 4195: Peroxisome proliferator-activated receptor α is regulated by E2F1-induced miR-19a in a feedback loop in glioma progression
Journal Articles

Abstract 444: Mitochondrial metabolism and phosphorylation of Stat3 in radioresistant cancer stem cells isolated from glioma U87 cells.

Ming Fan, Yan Shi, Jian Jian Li
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 444.
https://doi.org/10.1158/1538-7445.AM2013-444
Published: 15 April 2013
View article titled, Abstract 444: Mitochondrial metabolism and phosphorylation of Stat3 in radioresistant cancer stem cells isolated from glioma U87 cells.
Journal Articles

Amla, an Ayuervedic herb induces apoptosis in pancreatic cancer cells by activating extracellular signal-regulated kinase

Yan Shi, Sanjay Batra, Sanjay Srivastava
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5471.
Published: 01 May 2008
View article titled, Amla, an Ayuervedic herb induces apoptosis in pancreatic cancer cells by activating extracellular signal-regulated kinase
Journal Articles

The poly(ADP-ribose) polymerase (PARP) inhibitor, ABT-888 potentiates the antitumor activity of temozolomide in the B16F10 syngeneic melanoma model: Correlation with pharmacokinetic levels and a reduction in poly(ADP-ribose) polymer by ELISA.

Luis Rodriguez, Joann Palma, Kenneth Jarvis, Velitchka Bontcheva-Diaz, Jason Stavropoulos, Gail Bukofzer, Luciana Godzicki, Milagros Colon-Lopez, Mary Saltarelli, Xuesong Liu, Yan Shi, Ran Guan, Yan Luo, Amanda Olson, Jennifer Bouska, Guidong Zhu, Thomas Penning, Vincent Giranda, Rick Lesniewski, Saul Rosenberg, David Frost, Cherrie Donawho
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4946.
Published: 01 May 2007
View article titled, The poly(ADP-ribose) polymerase (PARP) inhibitor, ABT-888 potentiates the antitumor activity of temozolomide in the B16F10 syngeneic melanoma model: Correlation with pharmacokinetic levels and a reduction in poly(ADP-ribose) polymer by ELISA.
Journal Articles

ABT-888, a potent PARP inhibitor, enhances the antitumor activities by a variety of chemotherapeutic agents in vivo.

Yan Luo, Cherrie Donawho, Xuesong Liu, Yanping Luo, Yan Shi, Ran Guan, Joann Palma, Guidong Zhu, Eric Johnson, Luis Rodriguez, Velitchka Bontcheva-Diaz, Nayereh Ghoreishi-Haack, Ken Jarvis, Jon Meulbroek, Debra Ferguson, Bryan Cox, Edward Han, Thomas McGonigal, Vered Klinghofer, Amanda Olson, Jennifer Bouska, Thomas Penning, Saul Rosenberg, David Frost, Vincent Giranda
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1457.
Published: 01 May 2007
View article titled, ABT-888, a potent PARP inhibitor, enhances the antitumor activities by a variety of chemotherapeutic agents <em>in vivo</em>.
Journal Articles

Benzyl isothiocyanate chemosensitizes BxPC-3 human pancreatic cancer cells to gemcitabine induced growth inhibition and apoptotic death

Yan Shi, Jeffery Richards, Ian Humphreys, Ruifen Zhang, Sanjay Srivastava
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4776.
Published: 01 May 2007
View article titled, Benzyl isothiocyanate chemosensitizes BxPC-3 human pancreatic cancer cells to gemcitabine induced growth inhibition and apoptotic death
Journal Articles

Triphala, an Ayuervedic Herbal Medicine inhibits in vitro and in vivo growth of pancreatic cancer cells

Yan Shi, Sanjay Srivastava
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): LB-142.
Published: 01 May 2007
View article titled, Triphala, an Ayuervedic Herbal Medicine inhibits in vitro and in vivo growth of pancreatic cancer cells
Journal Articles

Potent and selective inhibitors of Akt delay tumor growth and sensitize tumors to chemotherapy in vivo

Yan Luo, Alexander Shoemaker, Qun Li, Xuesong Liu, Yan Shi, Keith W. Woods, Sheela Thomas, Ron Dejong, Edward K. Han, Ran Guan, Thomas McGonigal, Vered Klinghofer, Andy Oleksijew, Michael Mitten, Jennifer Bouska, Tilman Oltersdorf, Saul H. Rosenberg, Vincent L. Giranda
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 400.
Published: 01 May 2005
View article titled, Potent and selective inhibitors of Akt delay tumor growth and sensitize tumors to chemotherapy <em>in vivo</em>
Journal Articles

Transforming growth factor-β and bombesin synergistically activate cyclooxygenase-2

Yanna Cao, Fazhi Li, Mark R. Hellmich, Yan-Shi Guo, Hongmiao Sheng, Courtney M. Townsend, Jr., Tien C. Ko
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 939.
Published: 01 April 2004
View article titled, Transforming growth factor-β and bombesin synergistically activate cyclooxygenase-2