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Yan Liu
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Journal Articles

Abstract PO3-04-09: Prognoses of Patients with Hormone Receptor-Positive andHuman Epidermal Growth Factor Receptor 2-Negative BreastCancer Receiving Neoadjuvant Chemotherapy before Surgery:A Retrospective Analysis

Jin Zhang, Yan Liu, Shichao Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-04-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-04-09
Published: 02 May 2024
View article titled, Abstract PO3-04-09: Prognoses of Patients with Hormone Receptor-Positive andHuman Epidermal Growth Factor Receptor 2-Negative BreastCancer Receiving Neoadjuvant Chemotherapy before Surgery:A Retrospective Analysis
Journal Articles

Abstract 4667: HDAC9 as a potential regulator of lenvatinib resistance in hepatocellular carcinoma

Yunong Xie, Minghe Zhang, Yan Liu, Linglin Liu, Alfred Sze-Lok Cheng, Stephanie Ma, Man Tong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4667.
https://doi.org/10.1158/1538-7445.AM2024-4667
Published: 22 March 2024
View article titled, Abstract 4667: HDAC9 as a potential regulator of lenvatinib resistance in hepatocellular carcinoma
Journal Articles

Abstract 6599: 3D genomic analysis reveals novel enhancer hijacking mechanisms caused by complex structural alterations that drive oncogene overexpression

Katelyn L. Mortenson, Courtney Dawes, Emily R. Wilson, Nathan E. Patchen, Hailey Johnson, Jason Gertz, Swneke D. Bailey, Yan Liu, Katherine E. Varley, Xiaoyang Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6599.
https://doi.org/10.1158/1538-7445.AM2024-6599
Published: 22 March 2024
View article titled, Abstract 6599: 3D genomic analysis reveals novel enhancer hijacking mechanisms caused by complex structural alterations that drive oncogene overexpression
Journal Articles

Abstract 7065: AMBRA1 coordinates mitochondrial function to regulate cancer stemness and tumorigenesis in hepatocellular carcinoma

Yan Liu, Yunong Xie, Yimiao He, Stephanie Ma, Man Tong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7065.
https://doi.org/10.1158/1538-7445.AM2024-7065
Published: 22 March 2024
View article titled, Abstract 7065: AMBRA1 coordinates mitochondrial function to regulate cancer stemness and tumorigenesis in hepatocellular carcinoma
Journal Articles

Abstract P6-03-06: Determining prognostic factors and optimal surgical intervention for young patients with triple-negative breast cancer

Yi-Zi Zheng, Yan Liu, Zhen-Han Deng, Guo-Wen Liu, Ni Xie
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-03-06.
https://doi.org/10.1158/1538-7445.SABCS22-P6-03-06
Published: 01 March 2023
View article titled, Abstract P6-03-06: Determining prognostic factors and optimal surgical intervention for young patients with triple-negative breast cancer
Journal Articles

Abstract 3249: Targeting polyploid giant cancer cells to overcome resistance to PARP inhibitors in ovarian cancer

Xudong Zhang, Jun Yao, Xiaoran Li, Na Niu, Yan Liu, Anil K. Sood, Jinsong Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3249.
https://doi.org/10.1158/1538-7445.AM2022-3249
Published: 15 June 2022
View article titled, Abstract 3249: Targeting polyploid giant cancer cells to overcome resistance to PARP inhibitors in ovarian cancer
Journal Articles

Abstract 5738: Transcriptomic profiles of response to neoadjuvant chemotherapy in patients with high-grade serous ovarian cancer

Sanghoon Lee, Li Zhao, Nicole D. Fleming, Joseph Celestino, Richard A. Hajek, Margaret B. Morgan, Yan Liu, Shannon N. Westin, Amir A. Jazaeri, Jinsong Liu, Jianhua Zhang, P Andrew Futreal, Anil K. Sood
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5738.
https://doi.org/10.1158/1538-7445.AM2022-5738
Published: 15 June 2022
View article titled, Abstract 5738: Transcriptomic profiles of response to neoadjuvant chemotherapy in patients with high-grade serous ovarian cancer
Journal Articles

Abstract 5558: Discovery of a novel Claudin 6 X 4-1BB bispecific antibody with potent anti-tumor activity through conditional 4-1BB activation

Jian Li, Wenqing Jiang, Yan Liu, Zhengyi Wang, Xi Chen, Taylor B. Guo
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5558.
https://doi.org/10.1158/1538-7445.AM2022-5558
Published: 15 June 2022
View article titled, Abstract 5558: Discovery of a novel Claudin 6 X 4-1BB bispecific antibody with potent anti-tumor activity through conditional 4-1BB activation
Journal Articles

Abstract 4228: Inhibition of B7-H3 by enoblituzumab elicits antitumor immune modulation in both innate and adaptive immunity

Yanni Zhang, Xuejun Liu, Xinyun Zhu, Zhen Sheng, Yan Liu, Zhengyi Wang, Taylor B. Guo
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4228.
https://doi.org/10.1158/1538-7445.AM2022-4228
Published: 15 June 2022
View article titled, Abstract 4228: Inhibition of B7-H3 by enoblituzumab elicits antitumor immune modulation in both innate and adaptive immunity
Journal Articles

Abstract 6298: The novel long noncoding RNA lncNeur promotes neuroblastoma by up-regulating AURKA and Myc expression

Jing Wu, Pei Yan Liu, Belamy Cheung, Glenn Marshall, Marcel Dinger, Tao Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6298.
https://doi.org/10.1158/1538-7445.AM2022-6298
Published: 15 June 2022
View article titled, Abstract 6298: The novel long noncoding RNA lncNeur promotes neuroblastoma by up-regulating AURKA and Myc expression
Journal Articles

PKM2 Is Essential for Bladder Cancer Growth and Maintenance

Yong Xia, Xing Wang, Yan Liu, Ellen Shapiro, Herbert Lepor, Moon-Shong Tang, Tung-Tien Sun, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (2022) 82 (4): 571–585.
https://doi.org/10.1158/0008-5472.CAN-21-0403
Published: 15 February 2022
View article titled, PKM2 Is Essential for Bladder Cancer Growth and Maintenance
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Includes: Supplementary data
Journal Articles

Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations

Paul Yenerall, Rahul K. Kollipara, Kimberley Avila, Michael Peyton, Christopher A. Eide, Daniel Bottomly, Shannon K. McWeeney, Yan Liu, Kenneth D. Westover, Brian J. Druker, John D. Minna, Ralf Kittler
Journal: Cancer Research
Cancer Res (2021) 81 (18): 4685–4695.
https://doi.org/10.1158/0008-5472.CAN-21-1153
Published: 15 September 2021
View article titled, Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations
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Includes: Supplementary data
Journal Articles

Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling

Cheng Kong, Xuebing Yan, Yefei Zhu, Huiyuan Zhu, Ying Luo, Peipei Liu, Sylvain Ferrandon, Matthew F. Kalady, Renyuan Gao, Jide He, Fang Yin, Xiao Qu, Jiayi Zheng, Yaohui Gao, Qing Wei, Yanlei Ma, Jun-Yan Liu, Huanlong Qin
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4485–4498.
https://doi.org/10.1158/0008-5472.CAN-21-0453
Published: 01 September 2021
View article titled, <em>Fusobacterium Nucleatum</em> Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling
Open the PDF for <em>Fusobacterium Nucleatum</em> Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling in another window
Includes: Supplementary data
Journal Articles

Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction

Hanumantha Rao Madala, Iiro Taneli Helenius, Wen Zhou, Evanna Mills, Yiyun Zhang, Yan Liu, Ana M. Metelo, Michelle L. Kelley, Surendra Punganuru, Kyung Bo Kim, Benjamin Olenchock, Eugene Rhee, Andrew M. Intlekofer, Othon Iliopoulos, Edward Chouchani, Jing-Ruey Joanna Yeh
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3492–3506.
https://doi.org/10.1158/0008-5472.CAN-20-0246
Published: 02 September 2020
View article titled, Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction
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Includes: Supplementary data
Journal Articles

Abstract 5741: Highly specific copy number variant-flagging algorithm using next-generation sequencing in cancer-predisposition genes

Sun Hee Rosenthal, Ke Zhang, Yan Liu, Renius Owen, Alla Smolgovsky, Arlene Buller-Burckle, Felicitas Lacbawan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5741.
https://doi.org/10.1158/1538-7445.AM2020-5741
Published: 15 August 2020
View article titled, Abstract 5741: Highly specific copy number variant-flagging algorithm using next-generation sequencing in cancer-predisposition genes
Journal Articles

ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia

Yi Shu, Yi Wang, Wen-Qiong Lv, Dan-Yi Peng, Juan Li, Hang Zhang, Guang-Jie Jiang, Bi-Jie Yang, Shan Liu, Jia Zhang, Yan-Hua Chen, Shi Tang, Ke-Xing Wan, Jun-Tao Yuan, Wei Guo, Guo Fu, Xin-Kun Qi, Zhi-Dai Liu, Hai-Yan Liu, Chao Yang, Ling-Huan Zhang, Fang-Jie Liu, Jie Yu, Peng-Hui Zhang, Bin Qu, Hui Zhao, Tong-Chuan He, Lin Zou
Journal: Cancer Research
Cancer Res (2020) 80 (5): 988–998.
https://doi.org/10.1158/0008-5472.CAN-19-1471
Published: 02 March 2020
View article titled, ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia
Open the PDF for ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

Abstract 1925: Establishment and characterization of 3D cancer organoids as clinically relevant ex vivo drug screening tools for cancer translational research and drug discovery

Xiaoxi Xu, Satya Pathi, Limei Shang, Yan Liu, Peng Han, Likun Zhang, Binchen Mao, Davy Ouyang, Henry Li, Wenqing Yang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1925.
https://doi.org/10.1158/1538-7445.AM2019-1925
Published: 01 July 2019
View article titled, Abstract 1925: Establishment and characterization of 3D cancer organoids as clinically relevant <em>ex vivo</em> drug screening tools for cancer translational research and drug discovery
Journal Articles

Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis

Weicang Wang, Jun Yang, Matthew L. Edin, Yuxin Wang, Ying Luo, Debin Wan, Haixia Yang, Chun-Qing Song, Wen Xue, Katherine Z. Sanidad, Mingyue Song, Heather A. Bisbee, Jennifer A. Bradbury, Guanjun Nan, Jianan Zhang, Pei-an Betty Shih, Kin Sing Stephen Lee, Lisa M. Minter, Daeyoung Kim, Hang Xiao, Jun-Yan Liu, Bruce D. Hammock, Darryl C. Zeldin, Guodong Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (8): 1822–1830.
https://doi.org/10.1158/0008-5472.CAN-18-3221
Published: 15 April 2019
View article titled, Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis
Open the PDF for Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract A16: The in vitro and in vivo activity of the pyrrolomycin marinopyrrole RL71 alone and combined with temsirolimus (TEM) in MYCN-amplified neuroblastoma (NB)

Timothy R. McGuire, Donald W. Coulter, Yan Liu, Yashpal S. Chhonker, Daryl J. Murry, Gracey R. Alexander, Erin M. McIntyre, Jason A. Sughroue, Graham J. Sharp, Rongshi Li
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): A16.
https://doi.org/10.1158/1538-7445.PEDCA17-A16
Published: 01 October 2018
View article titled, Abstract A16: The in vitro and in vivo activity of the pyrrolomycin marinopyrrole RL71 alone and combined with temsirolimus (TEM) in MYCN-amplified neuroblastoma (NB)
Journal Articles

NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model

Yan Liu, Yuyang Li, Shengwu Liu, Dennis O. Adeegbe, Camilla L. Christensen, Max M. Quinn, Ruben Dries, Shiwei Han, Kevin Buczkowski, Xiaoen Wang, Ting Chen, Peng Gao, Hua Zhang, Fei Li, Peter S. Hammerman, James E. Bradner, Steven N. Quayle, Kwok-Kin Wong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3709–3717.
https://doi.org/10.1158/0008-5472.CAN-18-0161
Published: 01 July 2018
View article titled, NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model
Open the PDF for NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model in another window
Includes: Supplementary data