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Journal Articles

NAT10 Phase Separation Regulates YTHDF1 Splicing to Promote Gastric Cancer Progression

Songyi Liu, Chunlin Lin, Xiang Lin, Penghang Lin, Ruofan He, Xiaoyu Pan, Yan Lin, Jianxin Ye, Guangwei Zhu
Journal: Cancer Research
Cancer Res (2024) 84 (19): 3207–3222.
https://doi.org/10.1158/0008-5472.CAN-23-4062
Published: 01 October 2024
View article titled, NAT10 Phase Separation Regulates YTHDF1 Splicing to Promote Gastric Cancer Progression
Open the PDF for NAT10 Phase Separation Regulates YTHDF1 Splicing to Promote Gastric Cancer Progression in another window
Includes: Supplementary data
Journal Articles

KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity

Yulong Qiang, Jiachen Fan, Chuanshuai Xie, Leilei Yan, Xiaofei Song, Nan Zhang, Yan Lin, Jie Xiong, Wei Zhang, Yu Liu, Lei Wei, Yu Li, Shizhen Chen, Kaiwei Liang, Feng Li
Journal: Cancer Research
Cancer Res (2024) 84 (8): 1252–1269.
https://doi.org/10.1158/0008-5472.CAN-23-2888
Published: 15 April 2024
View article titled, KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity
Open the PDF for KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity in another window
Includes: Supplementary data
Journal Articles

Abstract 1337: Characterization of anti-AXL CAR-NK cell therapy for the treatment of melanoma

Winston Hibler, Glenn Merlino, Yan Lin Yu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1337.
https://doi.org/10.1158/1538-7445.AM2024-1337
Published: 22 March 2024
View article titled, Abstract 1337: Characterization of anti-AXL CAR-NK cell therapy for the treatment of melanoma
Journal Articles

SUMOylation-Driven mRNA Circularization Enhances Translation and Promotes Lymphatic Metastasis of Bladder Cancer

Yue Zhao, Jiancheng Chen, Hanhao Zheng, Yuming Luo, Mingjie An, Yan Lin, Mingrui Pang, Yuanlong Li, Yao Kong, Wang He, Tianxin Lin, Changhao Chen
Journal: Cancer Research
Cancer Res (2024) 84 (3): 434–448.
https://doi.org/10.1158/0008-5472.CAN-23-2278
Published: 01 February 2024
View article titled, SUMOylation-Driven mRNA Circularization Enhances Translation and Promotes Lymphatic Metastasis of Bladder Cancer
Open the PDF for SUMOylation-Driven mRNA Circularization Enhances Translation and Promotes Lymphatic Metastasis of Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

Mutant KRAS Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma

Yao Kong, Yuming Luo, Shangyou Zheng, Jiabin Yang, Dingwen Zhang, Yue Zhao, Hanhao Zheng, Mingjie An, Yan Lin, Le Ai, Xiayao Diao, Qing Lin, Changhao Chen, Rufu Chen
Journal: Cancer Research
Cancer Res (2023) 83 (18): 3077–3094.
https://doi.org/10.1158/0008-5472.CAN-22-3997
Published: 15 September 2023
View article titled, Mutant <em>KRAS</em> Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma
Open the PDF for Mutant <em>KRAS</em> Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract P1-12-03: Antidiarrheal prophylaxis with loperamide for patients with lymph node-negative (N0) or micrometastatic (N1mi), HER2-positive breast cancer who received adjuvant pyrotinib plus nab-paclitaxel: a randomized sub-study of PHAEDRA

Changjun Wang, Yan Lin, Yidong Zhou, Feng Mao, Jinghong Guan, Songjie Shen, Xuejing Wang, Xiaohui Zhang, Yanna Zhang, Bo Pan, Ying Zhong, Li Peng, Yan Li, Xin Huang, Ying Xu, Qiang Sun
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P1-12-03.
https://doi.org/10.1158/1538-7445.SABCS22-P1-12-03
Published: 01 March 2023
View article titled, Abstract P1-12-03: Antidiarrheal prophylaxis with loperamide for patients with lymph node-negative (N0) or micrometastatic (N1mi), HER2-positive breast cancer who received adjuvant pyrotinib plus nab-paclitaxel: a randomized sub-study of PHAEDRA
Journal Articles

PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer

Li-Li Long, Si-Cong Ma, Ze-Qin Guo, Yan-Pei Zhang, Zhenzhen Fan, Li-Juan Liu, Li Liu, Duan-Duan Han, Meng-Xin Leng, Jian Wang, Xue-Jun Guo, Jia-Le Tan, Xiao-Ting Cai, Yan Lin, Xinghua Pan, De-Hua Wu, Xue Bai, Zhong-Yi Dong
Journal: Cancer Research
Cancer Res (2023) 83 (4): 568–581.
https://doi.org/10.1158/0008-5472.CAN-22-1740
Published: 15 February 2023
View article titled, PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer
Open the PDF for PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5395: DNA damage repair gene mutations predict the efficacy of platinum-based chemotherapy in colorectal cancer

Yan Lin, Jinyan Zhang, Xiaoli Liao, Yumei Zhang, Min Luo, Qian Li, Mingzhi Xie, Chaoyong Liang, Sina Liao, Yating Zheng, Xue Hu, Mengli Huang, Rong Liang, Yongqiang Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5395.
https://doi.org/10.1158/1538-7445.AM2022-5395
Published: 15 June 2022
View article titled, Abstract 5395: DNA damage repair gene mutations predict the efficacy of platinum-based chemotherapy in colorectal cancer
Journal Articles

Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer

Mingjie An, Hanhao Zheng, Jian Huang, Yan Lin, Yuming Luo, Yao Kong, Mingrui Pang, Dingwen Zhang, Jiabin Yang, Jiancheng Chen, Yuanlong Li, Changhao Chen, Tianxin Lin
Journal: Cancer Research
Cancer Res (2022) 82 (12): 2239–2253.
https://doi.org/10.1158/0008-5472.CAN-21-4349
Published: 15 June 2022
View article titled, Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer
Open the PDF for Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract OT1-12-03: Phase II study of pyrotinib plus nanoparticle albumin-bound (nab)-paclitaxel as adjuvant therapy for lymph node-negative (N0) or micrometastatic (N1mi), HER2-positive early breast cancer (PHAEDRA)

Changjun Wang, Yidong Zhou, Yan Lin, Feng Mao, Jinghong Guan, Xiaohui Zhang, Songjie Shen, Xuejing Wang, Yanna Zhang, Bo Pan, Ying Zhong, Li Peng, Xi Cao, Ru Yao, Xingtong Zhou, Chi Xu, Ying Xu, Qiang Sun
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): OT1-12-03.
https://doi.org/10.1158/1538-7445.SABCS21-OT1-12-03
Published: 15 February 2022
View article titled, Abstract OT1-12-03: Phase II study of pyrotinib plus nanoparticle albumin-bound (nab)-paclitaxel as adjuvant therapy for lymph node-negative (N0) or micrometastatic (N1mi), HER2-positive early breast cancer (PHAEDRA)
Journal Articles

Abstract P4-02-13: Comparison of lymph node ultrasound and pathological characteristics of breast cancer patients with positive and negative sentinel lymph node

Xuefei Wang, Shafei Wu, Guochao Zhang, Jiaxin Li, Jianhua Du, Yidong Zhou, Feng Mao, Yan Lin, Songjie Shen, Xiaohui Zhang, Qiang Sun
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-02-13.
https://doi.org/10.1158/1538-7445.SABCS19-P4-02-13
Published: 15 February 2020
View article titled, Abstract P4-02-13: Comparison of lymph node ultrasound and pathological characteristics of breast cancer patients with positive and negative sentinel lymph node
Journal Articles

Abstract P5-06-31: Morphological apocrine and mucinous features of breast carcinoma: Does histology matter for survival?

Changjun Wang, Yu Song, Hanjiang Zhu, Yidong Zhou, Feng Mao, Yan Lin, Yanna Zhang, Xiaohui Zhang, Songjie Shen, Ying Zhong, Xin Huang, Qiang Sun
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-06-31.
https://doi.org/10.1158/1538-7445.SABCS19-P5-06-31
Published: 15 February 2020
View article titled, Abstract P5-06-31: Morphological apocrine and mucinous features of breast carcinoma: Does histology matter for survival?
Journal Articles

Abstract P5-12-14: The impact of pre-existed and SERM-induced non-alcoholic fatty liver disease on breast cancer survival: A meta-analysis

Yu Song, Changjun Wang, Wei Huang, Yidong Zhou, Ziyuan Chen, Hanjiang Zhu, Feng Mao, Yan Lin, Xiaohui Zhang, Songjie Shen, Ying Zhong, Xin Huang, Chang Chen, Qiang Sun
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-12-14.
https://doi.org/10.1158/1538-7445.SABCS19-P5-12-14
Published: 15 February 2020
View article titled, Abstract P5-12-14: The impact of pre-existed and SERM-induced non-alcoholic fatty liver disease on breast cancer survival: A meta-analysis
Journal Articles

Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth

Yuan-Yuan Qu, Rui Zhao, Hai-Liang Zhang, Qian Zhou, Fu-Jiang Xu, Xuan Zhang, Wen-Hao Xu, Ning Shao, Shu-Xian Zhou, Bo Dai, Yao Zhu, Guo-Hai Shi, Yi-Jun Shen, Yi-Ping Zhu, Cheng-Tao Han, Kun Chang, Yan Lin, Wei-Dong Zang, Wei Xu, Ding-Wei Ye, Shi-Min Zhao, Jian-Yuan Zhao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (2): 319–333.
https://doi.org/10.1158/0008-5472.CAN-19-1023
Published: 15 January 2020
View article titled, Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth
Open the PDF for Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth in another window
Includes: Supplementary data
Journal Articles

Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth

Galina V. Shurin, Oleg Kruglov, Fei Ding, Yan Lin, Xingxing Hao, Anton A. Keskinov, Zhaoyang You, Anna E. Lokshin, William A. LaFramboise, Louis D. Falo, Jr, Michael R. Shurin, Yuri L. Bunimovich
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2736–2747.
https://doi.org/10.1158/0008-5472.CAN-18-3872
Published: 15 May 2019
View article titled, Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth
Open the PDF for Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth in another window
Includes: Supplementary data
Journal Articles

Abstract LB-360: JNKs-mediated phosphorylation of human stromal xbp1s regulates multiple myeloma growth & osteolysis

Risheng Chen, Guoshuang Xu, Wissam Beaino, Kai Lui, Xuemei Zeng, Nathan Yates, Rong Chong, Konstas Verdelis, G. David Roodman, Denise Toscani, Nicola Giuliani, Yan Lin, Carolyn J. Anderson, Hongjiao Ouyang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-360.
https://doi.org/10.1158/1538-7445.AM2018-LB-360
Published: 01 July 2018
View article titled, Abstract LB-360: JNKs-mediated phosphorylation of human stromal xbp1s regulates multiple myeloma growth &amp; osteolysis
Journal Articles

Abstract 4302: Long term monitoring of circulating regulatory T cells (Treg), myeloid derived suppressor cella (MDSC) and type I effector T cells in melanoma patients treated with neoadjuvant ipilimumab

Janet Retseck, Amanda Gillespie-Twardy, Alexis Nasr, Hui-Min Lin, Yan Lin, John Kirkwood, Lisa H. Butterfield, Haris Zahoor, Cindy Sander, Ahmad A. Tarhini
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4302.
https://doi.org/10.1158/1538-7445.AM2015-4302
Published: 01 August 2015
View article titled, Abstract 4302: Long term monitoring of circulating regulatory T cells (Treg), myeloid derived suppressor cella (MDSC) and type I effector T cells in melanoma patients treated with neoadjuvant ipilimumab
Journal Articles

Abstract P5-18-06: Trastuzumab can be safely administered concurrently with anthracycline for adjuvant treatment of HER2-positive breast cancer

Songjie Shen, Qiang Sun, Ying Xu, Yidong Zhou, Jinghong Guan, Feng Mao, Yan Lin, Xuejing Wang
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-18-06.
https://doi.org/10.1158/1538-7445.SABCS14-P5-18-06
Published: 01 May 2015
View article titled, Abstract P5-18-06: Trastuzumab can be safely administered concurrently with anthracycline for adjuvant treatment of HER2-positive breast cancer
Journal Articles

Abstract 2911: Immune related melanoma gene expression profile predicts neoadjuvant ipilimumab clinical benefit

Ahmad A. Tarhini, Yan Lin, Hui-Min Lin, Cindy Sander, William A. La Framboise, John M. Kirkwood
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2911.
https://doi.org/10.1158/1538-7445.AM2014-2911
Published: 01 October 2014
View article titled, Abstract 2911: Immune related melanoma gene expression profile predicts neoadjuvant ipilimumab clinical benefit
Journal Articles

Abstract CT207: Pharmacokinetic analysis of the HDAC inhibitor belinostat (PXD-101) and metabolites in patients with hepatic dysfunction

Brian Kiesel, Robert Parise, Yan Lin, Deborah Allen, Guru Reddy, Shanta Chawla, Richard Piekarz, Percy Ivy, Shivaani Kumar, Jan H. Beumer
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT207.
https://doi.org/10.1158/1538-7445.AM2014-CT207
Published: 01 October 2014
View article titled, Abstract CT207: Pharmacokinetic analysis of the HDAC inhibitor belinostat (PXD-101) and metabolites in patients with hepatic dysfunction