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Y.N. Vashisht Gopal
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Journal Articles

Abstract 3926: ARF6-dependent endocytic trafficking of the interferon-gamma receptor drives adaptive immune resistance and response to immune checkpoint blockade

Yinshen Wee, Junhua Wang, Emily C. Wilson, Coulson P. Rich, Aaron Rogers, Zhongzong Tong, Evelyn DeGroot, Y.N. Vashisht Gopal, Michael Davies, Huseyin Atakan Ekiz, Joshua K.H. Tay, Chris Stubben, Kenneth M. Boucher, Juan M. Oviedo, Keke C. Fairfax, Matthew A. Williams, Sheri L. Holmen, Roger K. Wolff, Allie H. Grossmann
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3926.
https://doi.org/10.1158/1538-7445.AM2024-3926
Published: 22 March 2024
View article titled, Abstract 3926: ARF6-dependent endocytic trafficking of the interferon-gamma receptor drives adaptive immune resistance and response to immune checkpoint blockade
Journal Articles

Abstract A05: Molecular, immunologic, metabolic, and radiomic associations of oxidative phosphorylation (OXPHOS) in melanoma brain metastases (MBMs)

Grant M. Fischer, Aikaterini Kotrotsou, Sara Ahmed, Pilar O’Neal, Iman Sahnoune, Y.N. Vashisht Gopal, Courtney Hudgens, Barbara Knighton, Rivka Colen, Michael T. Tetzlaff, Michael A. Davies
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): A05.
https://doi.org/10.1158/1538-7445.MEL2019-A05
Published: 02 October 2020
View article titled, Abstract A05: Molecular, immunologic, metabolic, and radiomic associations of oxidative phosphorylation (OXPHOS) in melanoma brain metastases (MBMs)
Journal Articles

ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma

Abibatou Ndoye, Anna Budina-Kolomets, Curtis H. Kugel, III, Marie R. Webster, Amanpreet Kaur, Reeti Behera, Vito W. Rebecca, Ling Li, Patricia A. Brafford, Qin Liu, Y.N. Vashisht Gopal, Michael A. Davies, Gordon B. Mills, Xiaowei Xu, Hong Wu, Meenhard Herlyn, Michael C. Nicastri, Jeffrey D. Winkler, Maria S. Soengas, Ravi K. Amaravadi, Maureen E. Murphy, Ashani T. Weeraratna
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5873–5885.
https://doi.org/10.1158/0008-5472.CAN-17-0907
Published: 31 October 2017
View article titled, ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma
Open the PDF for ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma in another window
Includes: Supplementary data
Journal Articles

Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit Patel, Cristiano G. Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7037–7047.
https://doi.org/10.1158/0008-5472.CAN-14-1392
Published: 30 November 2014
View article titled, Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Open the PDF for Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma in another window
Includes: Supplementary data
Journal Articles

Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

Y.N. Vashisht Gopal, Wanleng Deng, Scott E. Woodman, Kakajan Komurov, Prahlad Ram, Paul D. Smith, Michael A. Davies
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8736–8747.
https://doi.org/10.1158/0008-5472.CAN-10-0902
Published: 31 October 2010
View article titled, Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <em>Braf-</em>Mutant Human Cutaneous Melanoma Cells
Open the PDF for Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <em>Braf-</em>Mutant Human Cutaneous Melanoma Cells in another window
Includes: Supplementary data