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Journal Articles

Abstract 1796: Role of FASN in pancreatic neuroendocrine cancer cells survival

Benjamin M. Evers, Zeta Chow, Yekaterina Zaytseva, Eun Y. Lee, Courtney M. Townsend, Tianyan Gao, B. Mark Evers, Piotr G. Rychahou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1796.
https://doi.org/10.1158/1538-7445.AM2024-1796
Published: 22 March 2024
View article titled, Abstract 1796: Role of FASN in pancreatic neuroendocrine cancer cells survival
Journal Articles

Abstract 3230: Discovery of selective BRM (SMARCA2) ATPase inhibitors for the treatment of BRG1 (SMARCA4) mutant cancers

Janice Y. Lee, Nathan Brooks, Brandon Antonakos, Bryan Perria, Candace Langan, Bonita D. Jones, Robert Stephen Flack, Zhifang Li, David Terry, Ross Wallace, Robert Bondi, Gereint Sis, Ronee Baracani, Maralee McVean, Gabrielle Kolakowski, Dayo Osimboni, Kevin Wilson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3230.
https://doi.org/10.1158/1538-7445.AM2024-3230
Published: 22 March 2024
View article titled, Abstract 3230: Discovery of selective BRM (SMARCA2) ATPase inhibitors for the treatment of BRG1 (SMARCA4) mutant cancers
Journal Articles

Abstract 3585: DNA-PK inhibition to enhance radiation sensitivity in metastatic pancreatic neuroendocrine cancer

Piotr G. Rychahou, Aman Chauhan, Zeta Chow, Tadahide Izumi, Quan Chen, Eun Y. Lee, Dana Napier, Lowell Brian Anthony, Michael J. Cavnar, Courtney M. Townsend, B. Mark Evers
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3585.
https://doi.org/10.1158/1538-7445.AM2024-3585
Published: 22 March 2024
View article titled, Abstract 3585: DNA-PK inhibition to enhance radiation sensitivity in metastatic pancreatic neuroendocrine cancer
Journal Articles

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C

Chunling Hu, Anil Belur Nagaraj, Hermela Shimelis, Gemma Montalban, Kun Y. Lee, Huaizhi Huang, Carolyn A. Lumby, Jie Na, Lisa R. Susswein, Maegan E. Roberts, Megan L. Marshall, Susan Hiraki, Holly LaDuca, Elizabeth Chao, Amal Yussuf, Tina Pesaran, Susan L. Neuhausen, Christopher A. Haiman, Peter Kraft, Sara Lindstrom, Julie R. Palmer, Lauren R. Teras, Celine M. Vachon, Song Yao, Irene Ong, Katherine L. Nathanson, Jeffrey N. Weitzel, Nicholas Boddicker, Rohan Gnanaolivu, Eric C. Polley, Georges Mer, Gaofeng Cui, Rachid Karam, Marcy E. Richardson, Susan M. Domchek, Siddhartha Yadav, Kathleen S. Hruska, Jill Dolinsky, S. John Weroha, Steven N. Hart, Jacques Simard, Jean Yves Masson, Yuan-Ping Pang, Fergus J. Couch
Journal: Cancer Research
Cancer Res (2023) 83 (15): 2557–2571.
https://doi.org/10.1158/0008-5472.CAN-22-2319
Published: 01 August 2023
View article titled, Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C
Open the PDF for Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C in another window
Includes: Supplementary data
Journal Articles

Abstract B044: Exosomal cancer-type SLCO1B3 and ABCC3 as potential biomarkers of castration resistant prostate cancer

Erica L. Beatson, Kristi Y. Lee, Martina A. Knechel, Elijah R. Sommer, Roger Depaz, Emily N. Risdon, Andres F. Leon, Jonathan D. Strope, Douglas K. Price, Cindy H. Chau, William D. Figg
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B044.
https://doi.org/10.1158/1538-7445.PRCA2023-B044
Published: 02 June 2023
View article titled, Abstract B044: Exosomal cancer-type <em>SLCO1B3</em> and <em>ABCC3</em> as potential biomarkers of castration resistant prostate cancer
Journal Articles

Abstract B046: Multimodal biomarkers that predict the presence of Gleason pattern 4: Potential impact for active surveillance

Anna Y. Lee, David M. Berman, Robert Lesurf, Palak G. Patel, Walead Ebrahimizadeh, Jane Bayani, Laura A. Lee, Nadia Boufaied, Shamini Selvarajah, Tamara Jamaspishvili, Karl-Philippe Guérard, Dan Dion, Atsunari Kawashima, Gina M. Clarke, Nathan How, Chelsea L. Jackson, Eleonora Scarlata, Khurram Siddiqui, John B.A. Okello, Armen G. Aprikian, Madeleine Moussa, Antonio Finelli, Joseph Chin, Fadi Brimo, Glenn Bauman, Andrew Loblaw, Vasundara Venkateswaran, Ralph Buttyan, Simone Chevalier, Axel Thomson, Paul C. Park, D. Robert Siemens, Jacques Lapointe, Paul C. Boutros, John M.S. Bartlett
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B046.
https://doi.org/10.1158/1538-7445.PRCA2023-B046
Published: 02 June 2023
View article titled, Abstract B046: Multimodal biomarkers that predict the presence of Gleason pattern 4: Potential impact for active surveillance
Journal Articles

Abstract A045: Whole transcriptome analysis of paired African American prostate cancer cell lines

Kristi Y. Lee, Erica L. Beatson, Cindy H. Chau, Douglas K. Price, William D. Figg
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A045.
https://doi.org/10.1158/1538-7445.PRCA2023-A045
Published: 02 June 2023
View article titled, Abstract A045: Whole transcriptome analysis of paired African American prostate cancer cell lines
Journal Articles

Abstract 804: The temporal evolution in disease phenotype of COVID-19 hospitalisation, intensive care and case fatality rates in cancer patients across the United Kingdom (UKCCP)

Thomas Starkey, Maria C. Ionescu, Matthew W. Fittall, Michael Tilby, Alex Burnett, Rosie Hattersley, Sam Khan, Martin Little, Justin K. Liu, James R. Platt, Arvind Tripathy, Isabella Watts, Sophie Therese Williams, United Kingdom COVID Cancer Programme, Tom Fowler, Peter W. Johnson, Lennard Y. Lee
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 804.
https://doi.org/10.1158/1538-7445.AM2023-804
Published: 04 April 2023
View article titled, Abstract 804: The temporal evolution in disease phenotype of COVID-19 hospitalisation, intensive care and case fatality rates in cancer patients across the United Kingdom (UKCCP)
Journal Articles

Abstract 5548: Clinical management and decision making in early ER-positive breast cancers through improved prognosis and pathway directed molecular profiling

John M. Bartlett, Cheryl Crozier, Vinay K. Mittal, Dan Dion, Angela De Luca, Adam E. Sundby, Elizabeth Woroszchuk, Bradley d’Souza, Louis Gasparini, Mary Anne Quintayo, Mehar Chahal, Anna Y. Lee, Mathieu Larivière, Kyusung S. Park, Anupma Sharma, Jeffrey M. Smith, Seth Sadis, Daniel W. Rea, Melanie Spears, Jane Bayani
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5548.
https://doi.org/10.1158/1538-7445.AM2023-5548
Published: 04 April 2023
View article titled, Abstract 5548: Clinical management and decision making in early ER-positive breast cancers through improved prognosis and pathway directed molecular profiling
Journal Articles

Abstract 4093: Dual targeted CAR immunotherapy for neuroblastoma using γδ T cells

Hunter C. Jonus, Jasmine Y. Lee, Jordan A. Silva, H. Trent Spencer, Kelly C. Goldsmith
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4093.
https://doi.org/10.1158/1538-7445.AM2023-4093
Published: 04 April 2023
View article titled, Abstract 4093: Dual targeted CAR immunotherapy for neuroblastoma using γδ T cells
Journal Articles

Abstract 6366: A novel small molecule inhibitor of MAPK and PI3K ameliorates disease phenotypes in myelofibrosis

Christopher A. Bonham, Youngsoon Jang, Kevin Heist, Amanda Welton, Tanner Robison, Kathryn E. Luker, Gary D. Luker, Winston Y. Lee, Thomas L. Chenevert, Marcian Van Dort, Brian D. Ross
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6366.
https://doi.org/10.1158/1538-7445.AM2022-6366
Published: 15 June 2022
View article titled, Abstract 6366: A novel small molecule inhibitor of MAPK and PI3K ameliorates disease phenotypes in myelofibrosis
Journal Articles

Abstract 6103: Reshaping the myeloid-dependent pro-tumorigenic microenvironment in PDAC by targeting the extracellular adenosine pathway: A therapeutic opportunity

Vincenzo Graziano, Andreas Dannhorn, Kate Williamson, Heather Hulme, Hannah Buckley, Sheng Y. Lee, Sabita Islam, James E. Thaventhiran, Richard Goodwin, Rebecca Brais, Simon J. Dovedi, Alwin Schuller, Jim Eyles, Duncan I. Jodrell
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6103.
https://doi.org/10.1158/1538-7445.AM2022-6103
Published: 15 June 2022
View article titled, Abstract 6103: Reshaping the myeloid-dependent pro-tumorigenic microenvironment in PDAC by targeting the extracellular adenosine pathway: A therapeutic opportunity
Journal Articles

Abstract 107: Reciprocal Sox2 regulation by SMAD1 and SMAD3 is critical for anoikis resistance and metastasis in ovarian cancer

Zainab M. Shonibare, Mehri Monavarian, Kathleen O'Connell, Diego Altamore, Abigail Shelton, Shubham Mehta, Renata Jaskula-Sztul, Rebecca Phaeton, Andrew Berchuck, Andrew B. Nixon, Rebecca Arend, Nam Y. Lee, Ryan Miller, Nadine Hempel, Karthikeyan Mythreye
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 107.
https://doi.org/10.1158/1538-7445.AM2022-107
Published: 15 June 2022
View article titled, Abstract 107: Reciprocal Sox2 regulation by SMAD1 and SMAD3 is critical for anoikis resistance and metastasis in ovarian cancer
Journal Articles

Abstract 1992: Serine hydroxymethyltransferase-2 as regulator of oxidative stress and chemoradiation resistance in lung adenocarcinoma

Kunal R. Chaudhary, Connor J. Kinslow, Ling F. Ye, Pavan S. Upadhyayula, Eun Y. Lee, Ramon C. Sun, Simon K. Cheng
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1992.
https://doi.org/10.1158/1538-7445.AM2021-1992
Published: 01 July 2021
View article titled, Abstract 1992: Serine hydroxymethyltransferase-2 as regulator of oxidative stress and chemoradiation resistance in lung adenocarcinoma
Journal Articles

GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression

Hisae Yoshitomi, Kun Y. Lee, Ke Yao, Seung Ho Shin, Tianshun Zhang, Qiushi Wang, Souren Paul, Eunmiri Roh, Joohyun Ryu, Hanyong Chen, Faisal Aziz, Abhijit Chakraborty, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2021) 81 (4): 945–955.
https://doi.org/10.1158/0008-5472.CAN-20-1880
Published: 15 February 2021
View article titled, GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression
Open the PDF for GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression in another window
Includes: Supplementary data
Journal Articles

RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression

Srinivasa P. Kolapalli, Rinku Sahu, Nishant R. Chauhan, Kautilya K. Jena, Subhash Mehto, Saroj K. Das, Ashish Jain, Manaswini Rout, Rupesh Dash, Rajeeb K. Swain, David Y. Lee, Tor Erik Rusten, Santosh Chauhan, Swati Chauhan
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (2): 315–331.
https://doi.org/10.1158/0008-5472.CAN-20-1871
Published: 15 January 2021
View article titled, RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
Open the PDF for RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression in another window
Includes: Supplementary data
Journal Articles

YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma

Jenny Shim, Jasmine Y. Lee, Hunter C. Jonus, Amanda Arnold, Robert W. Schnepp, Kaitlyn M. Janssen, Victor Maximov, Kelly C. Goldsmith
Journal: Cancer Research
Cancer Res (2020) 80 (21): 4741–4753.
https://doi.org/10.1158/0008-5472.CAN-20-0025
Published: 03 November 2020
View article titled, YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
Open the PDF for YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract CT285: KEYNOTE-689: A phase 3 study of neoadjuvant and adjuvant pembrolizumab plus standard of care (SOC) in locally advanced (LA) head and neck squamous cell carcinoma (HNSCC)

Nancy Y. Lee, Ravindra Uppaluri, William Westra, Ezra E. Cohen, Robert I. Haddad, Stephane Temam, Christophe Le Tourneau, Rebecca Chernock, Sufia Safina, Arkadiy Klochikhin, Amichay Meirovitz, Irene Brana, Joy Yang Ge, Ramona F. Swaby, Cecilia Pinheiro, Douglas Adkins
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT285.
https://doi.org/10.1158/1538-7445.AM2020-CT285
Published: 15 August 2020
View article titled, Abstract CT285: KEYNOTE-689: A phase 3 study of neoadjuvant and adjuvant pembrolizumab plus standard of care (SOC) in locally advanced (LA) head and neck squamous cell carcinoma (HNSCC)
Journal Articles

Abstract 3990: Tri-compartment (epithelial, immune, fibroblast) patient-derived models of the tumor microenvironment from an immuno-genomic profiled cohort of early stage colorectal cancers

Lindsay H. Kua, Fiona Y. Lee, Christine L. Eng, Harini Srinivasan, Rahul Nahar, Janice H. Oh, Nicole Ann L. Gunn, Kai Xian Thng, Ashley S. Yong, Adrian C. Sim, Rebecca Lim, Nicole Boo, Simeen Malik, Michael T. Wong, Tze Guan Tan, Shu Wen S. Ho, Shirleen Soh, Wan Jun Lim, Macalinao Dominique Camat, Joe P. Yeong, Clarinda W. Chua, Wei Qiang Leow, Ramanuj DasGupta, Si-Lin Koo, Lewis Hong, Brian Henry, Tony K. Lim, Iain B. Tan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3990.
https://doi.org/10.1158/1538-7445.AM2020-3990
Published: 15 August 2020
View article titled, Abstract 3990: Tri-compartment (epithelial, immune, fibroblast) patient-derived models of the tumor microenvironment from an immuno-genomic profiled cohort of early stage colorectal cancers
Journal Articles

Abstract 3872: Spatial and multi-omics characterization of the tumor microenvironment in colorectal cancer

Christine L. Eng, Joe P. Yeong, Andy Nguyen, Amanda Y. Guo, Brenda Tay, Mei Mei Chang, Sherlly Lim, Clarinda W. Chua, Harini Srinivasan, Lindsay H. Kua, Fiona Y. Lee, Dominique C. Macalinao, ThinZar Aung, Anders J. Skanderup, Tony K. Lim, Iain B. Tan, Si-Lin Koo
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3872.
https://doi.org/10.1158/1538-7445.AM2020-3872
Published: 15 August 2020
View article titled, Abstract 3872: Spatial and multi-omics characterization of the tumor microenvironment in colorectal cancer