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Xue-Ru Wu
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Journal Articles

PKM2 Is Essential for Bladder Cancer Growth and Maintenance

Yong Xia, Xing Wang, Yan Liu, Ellen Shapiro, Herbert Lepor, Moon-Shong Tang, Tung-Tien Sun, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (2022) 82 (4): 571–585.
https://doi.org/10.1158/0008-5472.CAN-21-0403
Published: 15 February 2022
View articletitled, PKM2 Is Essential for Bladder Cancer Growth and Maintenance
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Includes: Supplementary data
Journal Articles

Abstract 5241: Nitric oxide-releasing naproxen prevents muscle invasive bladder cancer

Venkateshwar Madka, Altaf Mohammed, Qian Li, Yuting Zhang, Stanley Lightfoot, Xue-Ru Wu, Vernon Steele, Levy Kopelovich, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5241.
https://doi.org/10.1158/1538-7445.AM2016-5241
Published: 15 July 2016
View articletitled, Abstract 5241: Nitric oxide-releasing naproxen prevents muscle invasive bladder cancer
Journal Articles

ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms

Phillip L. Palmbos, Lidong Wang, Huibin Yang, Yin Wang, Jacob Leflein, McKenzie L. Ahmet, John E. Wilkinson, Chandan Kumar-Sinha, Gina M. Ney, Scott A. Tomlins, Stephanie Daignault, Lakshmi. P. Kunju, Xue-Ru Wu, Yair Lotan, Monica Liebert, Mats E. Ljungman, Diane M. Simeone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (23): 5155–5166.
https://doi.org/10.1158/0008-5472.CAN-15-0603
Published: 30 November 2015
View articletitled, ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms
Open the PDF for ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms in another window
Includes: Supplementary data
Journal Articles

Abstract 4653: Modulation of mTOR and p53 signaling using rapamycin plus CP-31398 inhibits growth and progression of urothelial carcinoma in-vivo

Venkateshwar Madka, Altaf Mohammed, Qian Li, Yuting Zhang, Laura Biddick, Jagan M.R. Patlolla, Stanley Lightfoot, Xue-Ru Wu, Vernon Steele, Levy Kopelovich, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4653.
https://doi.org/10.1158/1538-7445.AM2015-4653
Published: 01 August 2015
View articletitled, Abstract 4653: Modulation of mTOR and p53 signaling using rapamycin plus CP-31398 inhibits growth and progression of urothelial carcinoma in-vivo
Journal Articles

Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas

Feng He, Jonathan Melamed, Moon-shong Tang, Chuanshu Huang, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (2015) 75 (10): 2017–2028.
https://doi.org/10.1158/0008-5472.CAN-14-3067
Published: 13 May 2015
View articletitled, Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas
Open the PDF for Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas in another window
Includes: Supplementary data
Journal Articles

Abstract 619: Flavokawain A inhibits urinary bladder carcinogenesis in the UPII-SV40T transgenic mouse bladder cancer model.

Zhongbo Liu, Xuesen Li, Shuman liu, Xia Xu, Xuejiao Tian, Anne R. Simoneau, Xue-Ru Wu, Xiaolin Zi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 619.
https://doi.org/10.1158/1538-7445.AM2012-619
Published: 15 April 2012
View articletitled, Abstract 619: Flavokawain A inhibits urinary bladder carcinogenesis in the UPII-SV40T transgenic mouse bladder cancer model.
Journal Articles

Abstract 1325: Organ, species and sex differences in mutagenesis induced by butyl-hydroxybutyl-N-nitrosamine in big blue transgenic rodents as the basis for the strict organ specificity of this environmental carcinogen metabolite

Zhiming He, Zhong-Lin Zhao Strasberg-Rieber, Wieslawa Kosinska, Xue-Ru Wu, Joseph B. Guttenplan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1325.
https://doi.org/10.1158/1538-7445.AM2011-1325
Published: 15 April 2011
View articletitled, Abstract 1325: Organ, species and sex differences in mutagenesis induced by butyl-hydroxybutyl-N-nitrosamine in big blue transgenic rodents as the basis for the strict organ specificity of this environmental carcinogen metabolite
Journal Articles

Abstract 2442: XIAP mediates cancer cell motility via RhoGDI-dependent regulation of cytoskeleton

Yonghui Yu, Jinyi Liu, Dongyun Zhang, Wenjing Luo, Jianxiu Yu, Jingxia Li, Xinhai Zhang, Xue-Ru Wu, Germán R. Acosta, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2442.
https://doi.org/10.1158/1538-7445.AM2011-2442
Published: 15 April 2011
View articletitled, Abstract 2442: XIAP mediates cancer cell motility via RhoGDI-dependent regulation of cytoskeleton
Journal Articles

Abstract 1475: Molecular mechanisms of “SNAIL” activation in invasive bladder cancer of p53/Rb double knockout mice exposed to chemical carcinogen BBN

Hye Na Kim, Feng He, Narayanan K. Narayanan, Jiri Zavadil, Xue-Ru Wu, Bhagavathi Narayanan
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1475.
https://doi.org/10.1158/1538-7445.AM10-1475
Published: 15 April 2010
View articletitled, Abstract 1475: Molecular mechanisms of “SNAIL” activation in invasive bladder cancer of p53/Rb double knockout mice exposed to chemical carcinogen BBN
Journal Articles

Deficiency of pRb Family Proteins and p53 in Invasive Urothelial Tumorigenesis

Feng He, Lan Mo, Xiao-Yong Zheng, Changkun Hu, Herbert Lepor, Eva Y-H.P. Lee, Tung-Tien Sun, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (2009) 69 (24): 9413–9421.
https://doi.org/10.1158/0008-5472.CAN-09-2158
Published: 14 December 2009
View articletitled, Deficiency of pRb Family Proteins and p53 in Invasive Urothelial Tumorigenesis
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Includes: Supplementary data
Journal Articles

The histone deacetylase (HDAC) inhibitor PXD101 suppresses bladder cancer cell growth both in-vitro and in-vivo.

Michael Buckley, Joanne Yoon, Neda Simaika, Herman Yee, Luis Chiriboga, Leonard Liebes, Ara Gulshan, Xiaozhong Qian, Tung-Tien Sun, Xue-Ru Wu, Iman Osman
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2211.
Published: 01 May 2007
View articletitled, The histone deacetylase (HDAC) inhibitor PXD101 suppresses bladder cancer cell growth both in-vitro and in-vivo.
Journal Articles

A Survivin Gene Signature Predicts Aggressive Tumor Behavior

Whitney Salz, Dan Eisenberg, Janet Plescia, David S. Garlick, Robert M. Weiss, Xue-Ru Wu, Tung-Tien Sun, Dario C. Altieri
Journal: Cancer Research
Cancer Res (2005) 65 (9): 3531–3534.
https://doi.org/10.1158/0008-5472.CAN-04-4284
Published: 02 May 2005
View articletitled, A Survivin Gene Signature Predicts Aggressive Tumor Behavior
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Includes: Supplementary data
Journal Articles

Differential Expression of Cell Cycle Regulators in Phenotypic Variants of Transgenically Induced Bladder Tumors: Implications for Tumor Behavior

Antonio Garcia-España, Edgard Salazar, Tung-Tien Sun, Xue-Ru Wu, Angel Pellicer
Journal: Cancer Research
Cancer Res (2005) 65 (4): 1150–1157.
https://doi.org/10.1158/0008-5472.CAN-04-2074
Published: 25 February 2005
View articletitled, Differential Expression of Cell Cycle Regulators in Phenotypic Variants of Transgenically Induced Bladder Tumors: Implications for Tumor Behavior
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Journal Articles

Magnetic resonance imaging for detection of urothelial tumor formation in Ha-ras transgenic mice

Jorge Dela Cerda, Roger E. Price, Xue-Ru Wu, H. Barton Grossman, Anita L. Sabichi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1181.
Published: 01 April 2004
View articletitled, Magnetic resonance imaging for detection of urothelial tumor formation in Ha-ras transgenic mice
Journal Articles

Allelic Loss of p53 Gene Is Associated with Genesis and Maintenance, but not Invasion, of Mouse Carcinoma in Situ of the Bladder

Jin Cheng, Hongying Huang, Joanne Pak, Ellen Shapiro, Tung-Tien Sun, Carlos Cordon-Cardo, Frederic M. Waldman, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (2003) 63 (1): 179–185.
Published: 01 January 2003
View articletitled, Allelic Loss of p53 Gene Is Associated with Genesis and Maintenance, but not Invasion, of Mouse Carcinoma in Situ of the Bladder
Open the PDF for Allelic Loss of p53 Gene Is Associated with Genesis and Maintenance, but not Invasion, of Mouse Carcinoma in Situ of the Bladder in another window
Journal Articles

Overexpression of Epidermal Growth Factor Receptor in Urothelium Elicits Urothelial Hyperplasia and Promotes Bladder Tumor Growth

Jin Cheng, Hongying Huang, Zhong-Ting Zhang, Ellen Shapiro, Angel Pellicer, Tung-Tien Sun, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (2002) 62 (14): 4157–4163.
Published: 15 July 2002
View articletitled, Overexpression of Epidermal Growth Factor Receptor in Urothelium Elicits Urothelial Hyperplasia and Promotes Bladder Tumor Growth
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Journal Articles

Urothelium-specific Expression of an Oncogene in Transgenic Mice Induced the Formation of Carcinoma in Situ and Invasive Transitional Cell Carcinoma

Zhong-Ting Zhang, Joanne Pak, Ellen Shapiro, Tung-Tien Sun, Xue-Ru Wu
Journal: Cancer Research
Cancer Res (1999) 59 (14): 3512–3517.
Published: 15 July 1999
View articletitled, Urothelium-specific Expression of an Oncogene in Transgenic Mice Induced the Formation of Carcinoma in Situ and Invasive Transitional Cell Carcinoma
Open the PDF for Urothelium-specific Expression of an Oncogene in Transgenic Mice Induced the Formation of Carcinoma in Situ and Invasive Transitional Cell Carcinoma in another window
Journal Articles

Uroplakin II Gene Is Expressed in Transitional Cell Carcinoma But Not in Bilharzial Bladder Squamous Cell Carcinoma: Alternative Pathways of Bladder Epithelial Differentiation and Tumor Formation

Ren-Long Wu, Iman Osman, Xue-Ru Wu, Ming-Lan Lu, Zuo-Feng Zhang, Feng-Xia Liang, Reda Hamza, Howard Scher, Carlos Cordon-Cardo, Tung-Tien Sun
Journal: Cancer Research
Cancer Res (1998) 58 (6): 1291–1297.
Published: 01 March 1998
View articletitled, Uroplakin II Gene Is Expressed in Transitional Cell Carcinoma But Not in Bilharzial Bladder Squamous Cell Carcinoma: Alternative Pathways of Bladder Epithelial Differentiation and Tumor Formation
Open the PDF for Uroplakin II Gene Is Expressed in Transitional Cell Carcinoma But Not in Bilharzial Bladder Squamous Cell Carcinoma: Alternative Pathways of Bladder Epithelial Differentiation and Tumor Formation in another window