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Journal Articles

Abstract 3111: PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors

Xu Zhang, Jiao Xu, Xuan Wang, Lan Xu, Xi Zhang, Yi Wang, Shujuan Jiang, Yixiang Zhang, Jian Ding, Chen Qing, Linghua Meng
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3111.
https://doi.org/10.1158/1538-7445.AM2025-3111
Published: 21 April 2025
View articletitled, Abstract 3111: PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors
Journal Articles

Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution

Tao Wu, Guangshuai Wang, Xuan Wang, Shixiang Wang, Xiangyu Zhao, Chenxu Wu, Wei Ning, Ziyu Tao, Fuxiang Chen, Xue-Song Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12): 2226–2238.
https://doi.org/10.1158/0008-5472.CAN-21-3717
Published: 15 June 2022
View articletitled, Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution
Open the PDF for Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution in another window
Includes: Supplementary data
Journal Articles

Abstract 6199: Fusion genes: Novel therapeutic targets for gastric signet ring cell carcinoma

Yue Wang, Tao Shi, Xuan Wang, Jinwei Hu, Lixia Yu, Qin Liu, Nandie Wu, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6199.
https://doi.org/10.1158/1538-7445.AM2022-6199
Published: 15 June 2022
View articletitled, Abstract 6199: Fusion genes: Novel therapeutic targets for gastric signet ring cell carcinoma
Journal Articles

Abstract 1108: A new mechanism of drug resistance in cancer: Extracellular ATP-induced resistance through ATP internalization and upregulation of ATP-binding cassette multidrug transporters

Haiyun Zhang, Xuan Wang, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1108.
https://doi.org/10.1158/1538-7445.AM2021-1108
Published: 01 July 2021
View articletitled, Abstract 1108: A new mechanism of drug resistance in cancer: Extracellular ATP-induced resistance through ATP internalization and upregulation of ATP-binding cassette multidrug transporters
Journal Articles

Abstract CT035: Safety/tolerability and preliminary antitumor activity of sitravatinib plus tislelizumab in patients with PD-(L)1 refractory/resistant unresectable or metastatic melanoma from a phase 1b study

Chuanliang Cui, Hongming Pan, Matteo Carlino, Jiuwei Cui, Xuan Wang, Cheng Chen, Xiao Xiang, Liu Yang, Jun Guo
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT035.
https://doi.org/10.1158/1538-7445.AM2021-CT035
Published: 01 July 2021
View articletitled, Abstract CT035: Safety/tolerability and preliminary antitumor activity of sitravatinib plus tislelizumab in patients with PD-(L)1 refractory/resistant unresectable or metastatic melanoma from a phase 1b study
Journal Articles

The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/β-Catenin Signaling

Dakota N. Jackson, Kibrom M. Alula, Yaritza Delgado-Deida, Redouane Tabti, Kevin Turner, Xuan Wang, K. Venuprasad, Rhonda F. Souza, Laurent Désaubry, Arianne L. Theiss
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3519–3529.
https://doi.org/10.1158/0008-5472.CAN-20-0216
Published: 02 September 2020
View articletitled, The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/β-Catenin Signaling
Open the PDF for The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/β-Catenin Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 1521: New roles of ATP in metastasis: Extracellular and macropinocytosis internalized ATP work together to induces epithelial to mesenchymal transition and other early steps of metastasis

Yanyang Cao, Xuan Wang, Maria Evers, Yunsheng Li, Haiyun Zhang, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1521.
https://doi.org/10.1158/1538-7445.AM2020-1521
Published: 15 August 2020
View articletitled, Abstract 1521: New roles of ATP in metastasis: Extracellular and macropinocytosis internalized ATP work together to induces epithelial to mesenchymal transition and other early steps of metastasis
Journal Articles

Abstract 3008: A new mechanism of drug resistance in cancer: Extracellular ATP-induced resistance through ATP internalization and upregulation of ATP-binding cassette multidrug transporters

Haiyun Zhang, Xuan Wang, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3008.
https://doi.org/10.1158/1538-7445.AM2020-3008
Published: 15 August 2020
View articletitled, Abstract 3008: A new mechanism of drug resistance in cancer: Extracellular ATP-induced resistance through ATP internalization and upregulation of ATP-binding cassette multidrug transporters
Journal Articles

Abstract 2007: Development of a clinical assay for predicting glioblastoma (GBM) patients most likely to respond to arsenic trioxide (ATO)

Sen Peng, Jinghua Gu, Xuan Wang, Sanhita Rath, Jacob Cardenas, Nicholas Schork, George Snipes, Harshil Dhruv, Karen Fink, Michael Berens
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2007.
https://doi.org/10.1158/1538-7445.AM2020-2007
Published: 15 August 2020
View articletitled, Abstract 2007: Development of a clinical assay for predicting glioblastoma (GBM) patients most likely to respond to arsenic trioxide (ATO)
Journal Articles

Abstract P5-04-10: Immune and transcriptional signatures of dendritic cell (DC) vaccination combined with chemotherapy in locally advanced, triple-negative breast cancer (TNBC) patients

Te-Chia Wu, Joyce O’Shaughnessy, Lee K. Roberts, Jennifer L. Smith, Susan B. Burkeholder, Jennifer Finholt, Jessica Tarnowski, Tuoc Dao, Jeffrey Lamont, Sandra M. Zurawski, Phuong Nguyen, Yuanyuan Wang, Kyung In Kim, Derek Blankenship, Jacob Turner, Xuan Wang, Florentina Marches, Maren K. Levin, Michael Grant, Gerard Zurawski, Virginia Pascual, Jacques Banchereau, Karolina Palucka
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-04-10.
https://doi.org/10.1158/1538-7445.SABCS19-P5-04-10
Published: 15 February 2020
View articletitled, Abstract P5-04-10: Immune and transcriptional signatures of dendritic cell (DC) vaccination combined with chemotherapy in locally advanced, triple-negative breast cancer (TNBC) patients
Journal Articles

IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer

Te-Chia Wu, Kangling Xu, Jan Martinek, Robyn R. Young, Romain Banchereau, Joshy George, Jacob Turner, Kyung In Kim, Sandra Zurawski, Xuan Wang, Derek Blankenship, Hannah M. Brookes, Florentina Marches, Gerlinde Obermoser, Elizabeth Lavecchio, Maren K. Levin, Sookyoung Bae, Cheng-Han Chung, Jennifer L. Smith, Alma-Martina Cepika, Kyp L. Oxley, George J. Snipes, Jacques Banchereau, Virginia Pascual, Joyce O'Shaughnessy, A. Karolina Palucka
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (18): 5243–5258.
https://doi.org/10.1158/0008-5472.CAN-18-0413
Published: 14 September 2018
View articletitled, IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer
Open the PDF for IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2651: A mesenchymal-associated transcriptomic signature has a prognostic and predictive potential in stage II and III colorectal cancer patients

Takatoshi Matsuyama, Raju Kandimalla, Xuan Wang, Toshiaki Ishikawa, Naoki Takahashi, Yasuhide Yamada, Masamichi Yasuno, Yusuke Kinugasa, Hiroyuki Uetake, Ajay Goel
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2651.
https://doi.org/10.1158/1538-7445.AM2018-2651
Published: 01 July 2018
View articletitled, Abstract 2651: A mesenchymal-associated transcriptomic signature has a prognostic and predictive potential in stage II and III colorectal cancer patients
Journal Articles

Abstract 2846: Extracellular ATP induces different types of drug resistances in cancer cells through ATP internalization-mediated intracellular ATP level increase

Xiaozhuo Chen, Xuan Wang, Haiyun Zhang, Yanrong Qian, Yunsheng Li, Yanyang Cao, Pratik Shriwas
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2846.
https://doi.org/10.1158/1538-7445.AM2018-2846
Published: 01 July 2018
View articletitled, Abstract 2846: Extracellular ATP induces different types of drug resistances in cancer cells through ATP internalization-mediated intracellular ATP level increase
Journal Articles

Abstract 2019: Extracellular ATP induces EMT and metastatic activities in non-small cell lung cancer cells

Yanyang Cao, Xuan Wang, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2019.
https://doi.org/10.1158/1538-7445.AM2018-2019
Published: 01 July 2018
View articletitled, Abstract 2019: Extracellular ATP induces EMT and metastatic activities in non-small cell lung cancer cells
Journal Articles

Abstract 2799: New-generation glucose transporter inhibitors targeting non-small cell lung cancer and triple-negative breast cancer

Pratik Shriwas, Yanrong Qian, Xuan Wang, Dennis Roberts, Stephen Bergmeier, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2799.
https://doi.org/10.1158/1538-7445.AM2018-2799
Published: 01 July 2018
View articletitled, Abstract 2799: New-generation glucose transporter inhibitors targeting non-small cell lung cancer and triple-negative breast cancer
Journal Articles

Abstract 1968: A novel mechanism of metastasis: Extracellular ATP promotes invasion and metastasis independent of purinergic receptor signaling

Yanyang Cao, Xuan Wang, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1968.
https://doi.org/10.1158/1538-7445.AM2017-1968
Published: 01 July 2017
View articletitled, Abstract 1968: A novel mechanism of metastasis: Extracellular ATP promotes invasion and metastasis independent of purinergic receptor signaling
Journal Articles

Abstract 1157: Screening and identification of new generation glucose transporter inhibitors as anticancer therapeutics

Yanrong Qian, Pratik Shriwas, Xuan Wang, Dennis Roberts, Emma Kessler, Stephen Bergmeier, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1157.
https://doi.org/10.1158/1538-7445.AM2017-1157
Published: 01 July 2017
View articletitled, Abstract 1157: Screening and identification of new generation glucose transporter inhibitors as anticancer therapeutics
Journal Articles

Abstract 3194: A new mechanism of drug resistance in cancer: extracellular ATP-induced resistance through ATP internalization and upregulation of protein phosphorylation in Akt and ERK pathways

Xuan Wang, Yunsheng Li, Yanrong Qian, Yanyang Cao, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3194.
https://doi.org/10.1158/1538-7445.AM2017-3194
Published: 01 July 2017
View articletitled, Abstract 3194: A new mechanism of drug resistance in cancer: extracellular ATP-induced resistance through ATP internalization and upregulation of protein phosphorylation in Akt and ERK pathways
Journal Articles

Abstract 33: NSCLC cells internalize ATP in vitro and in vivo using multiple endocytotic pathways

Yanrong Qian, Xuan Wang, Yunsheng Li, Yanyang Cao, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 33.
https://doi.org/10.1158/1538-7445.AM2016-33
Published: 15 July 2016
View articletitled, Abstract 33: NSCLC cells internalize ATP in vitro and in vivo using multiple endocytotic pathways
Journal Articles

Abstract 42: A new type of drug resistance in cancer: extracellular ATP-induced resistance through ATP internalization and ATP-drug competition

Xuan Wang, Yunsheng Li, Yanrong Qian, Yanyang Cao, Xiaozhuo Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 42.
https://doi.org/10.1158/1538-7445.AM2016-42
Published: 15 July 2016
View articletitled, Abstract 42: A new type of drug resistance in cancer: extracellular ATP-induced resistance through ATP internalization and ATP-drug competition