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Journal Articles

Abstract 7461: Identifying molecular vulnerabilities in rare cancers using a novel graph-based therapeutic discovery model

Free
Li Zhao, Ying Zhu, Randy Chu, Haifeng Zhu, Stephanie T. Schmidt, Yuntao Yang, Chunjie Jiang, Mark Knafl, Xingzhi Song, Xiaogang Wu, Jianhua Zhang, Sabitha Prabhakaran, Scott Woodman, Timothy Heffernan, Elizabeth Burton, Rare Tumor Initiative Team, Andy Futreal, Bissan Al-Lazikani
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7461.
https://doi.org/10.1158/1538-7445.AM2025-7461
Published: 21 April 2025
View articletitled, Abstract 7461: Identifying molecular vulnerabilities in rare cancers using a novel graph-based therapeutic discovery model
Journal Articles

Abstract PO2-09-05: Building genomic and transcriptomic data among African American and Black patients with triple-negative inflammatory breast cancer

Free
Wencai Ma, Li Zhao, Gayathri Devi, Savitri Krishnamurthy, Larry Coffer, Angela Alexander, Megumi Kai, Xiaoping Wang, Huong Le-Petross, Miral Patel, Bisrat Debeb, Chandra Bartholomeusz, Jianhua Zhang, Xingzhi Song, Andrew Futreal, Naoto Ueno, Rachel Layman, Anthony Lucci, Jing Wang, Wendy Woodward
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-09-05.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-09-05
Published: 02 May 2024
View articletitled, Abstract PO2-09-05: Building genomic and transcriptomic data among African American and Black patients with triple-negative inflammatory breast cancer
Journal Articles

Abstract 3387: Spatial analysis revealed distinct molecular and immune landscape in genetic versus carcinogen-induced lung adenocarcinoma precancer mouse models

Free
Bo Zhu, Pingjun Chen, Jian-Rong Li, Muhammad Aminu, Chenyang Li, Hong Chen, Yanhua Tian, Frank R. Rojas, Parra Cuentas Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Shawna M. Hubert, Khaja B. Khan, Wei Lu, Xingzhi Song, Jianhua Zhang, Don L. Gibbons, Luisa M. Solis Soto, Ignacio I. Wistuba, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3387.
https://doi.org/10.1158/1538-7445.AM2024-3387
Published: 22 March 2024
View articletitled, Abstract 3387: Spatial analysis revealed distinct molecular and immune landscape in genetic versus carcinogen-induced lung adenocarcinoma precancer mouse models
Journal Articles

Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity

Free
Dominik Awad, Pham Hong Anh Cao, Thomas L. Pulliam, Meredith Spradlin, Elavarasan Subramani, Tristen V. Tellman, Caroline F. Ribeiro, Riccardo Muzzioli, Brittany E. Jewell, Hubert Pakula, Jeffrey J. Ackroyd, Mollianne M. Murray, Jenny J. Han, Mei Leng, Antrix Jain, Badrajee Piyarathna, Jingjing Liu, Xingzhi Song, Jianhua Zhang, Albert R. Klekers, Justin M. Drake, Michael M. Ittmann, Cristian Coarfa, David Piwnica-Worms, Mary C. Farach-Carson, Massimo Loda, Livia S. Eberlin, Daniel E. Frigo
Journal: Cancer Research
Cancer Res (2024) 84 (5): 703–724.
https://doi.org/10.1158/0008-5472.CAN-23-0555
Published: 04 March 2024
View articletitled, Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity
Open the PDF for Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity in another window
Includes: Supplementary data
Journal Articles

Abstract A029: DDR pathway genes in CRT resistance: Insights from longitudinal whole exome sequencing in cervical cancer

Free
Shafqat F. Ehsan, Rui Wang, Xiaogang Wu, Tatiana V. Karpinets, Julianna K. Bronk, Chiraag Kapadia, Xingzhi Song, Andrew M. Futreal, Ann H. Klopp, Tim Harris, Jianhua Zhang, Lauren E. Colbert
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): A029.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-A029
Published: 09 January 2024
View articletitled, Abstract A029: DDR pathway genes in CRT resistance: Insights from longitudinal whole exome sequencing in cervical cancer
Journal Articles

Abstract 2375: Whole exome sequencing and immune profiling of cervical adenocarcinoma reveal a “cold” tumor-immune phenotype

Free
Julianna Bronk, Xiaogang Wu, Rui Wang, Ananta Yanamandra, Tatiana Karpinets, Chike Abana, Molly El Alam, Katarina Tomasic, Daniel Lin, Erica Lynn, David Lo, Timothy Harris, Xingzhi Song, Andrew Futreal, Jianhua Zhang, Jagannadha Sastry, Ann Klopp, Lauren Colbert
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2375.
https://doi.org/10.1158/1538-7445.AM2023-2375
Published: 04 April 2023
View articletitled, Abstract 2375: Whole exome sequencing and immune profiling of cervical adenocarcinoma reveal a “cold” tumor-immune phenotype
Journal Articles

Abstract 97: Multiregional profiling revealed intra-tumor transcriptomic heterogeneity associated with the prognosis in non-small cell lung cancer

Free
Chenyang Li, Thinh T. Nguyen, Jian-Rong Li, Xingzhi Song, Ignacio I. Wistuba, Andy Futureal, Jianhua Zhang, Shawna M. Hubert, Jia Wu, Jianjun Zhang, Chao Cheng
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 97.
https://doi.org/10.1158/1538-7445.AM2023-97
Published: 04 April 2023
View articletitled, Abstract 97: Multiregional profiling revealed intra-tumor transcriptomic heterogeneity associated with the prognosis in non-small cell lung cancer
Journal Articles

Abstract 5473: Genomic profiling of chemotherapy-related clonal hematopoiesis in patients with high-grade serous ovarian cancer

Free
Sara Corvigno, Jun Yao, Li Zhao, Amma Asare, Joseph Celestino, Richard Hajek, Ency Arboleda Goette, Elaine Stur, Emine Bayraktar, Mark S Kim, Ping Song, Qingxiu Zhang, Xingzhi Song, Mohammad Mohammad, Kenna Shaw, Jianhua Zhang, Karen Lu, Amir Jazaeri, Shannon Westin, Anil Sood, Sanghoon Lee
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5473.
https://doi.org/10.1158/1538-7445.AM2023-5473
Published: 04 April 2023
View articletitled, Abstract 5473: Genomic profiling of chemotherapy-related clonal hematopoiesis in patients with high-grade serous ovarian cancer
Journal Articles

Abstract 1395: Genomic and transcriptomic analyses identify distinct features of triple-negative inflammatory breast cancer

Free
Xiaoping Wang, Li Zhao, Takashi Semba, Xingzhi Song, Mark Knafl, Savitri Krishnamurthy, Shan Shao, Larry W. Coffer, II, Angela Alexander, Anita Wood, Swetha Bopparaju, Wendy A. Woodward, Randy Chu, Jianhua Zhang, Scott Woodman, Andrew Futreal, Clinton Yam, Debu Tripathy, Naoto T. Ueno
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1395.
https://doi.org/10.1158/1538-7445.AM2023-1395
Published: 04 April 2023
View articletitled, Abstract 1395: Genomic and transcriptomic analyses identify distinct features of triple-negative inflammatory breast cancer
Journal Articles

Abstract 6513: Single cell and spatial profiling reveal molecular and immune evolution from precancers to invasive lung adenocarcinomas in genetic and carcinogen-induced mouse models

Free
Bo Zhu, Jian-Rong Li, Hong Chen, Pingjun Chen, Junya Fujimoto, Yanhua Tian, Muhammad Aminu, Chenyang Li, Lingzhi Hong, Alexandre Reuben, Edwin Roger Parra Cuentas, Ou Shi, Monique Nilsson, Alissa Poteete, Shawna Hubert, Khaja Khan, Wei Lu, Daniel Kraushaar, Xingzhi Song, Jianhua Zhang, Don Gibbons, Luisa Solis Soto, Ignacio Wistuba, Jia Wu, John Heymach, Chao Cheng, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6513.
https://doi.org/10.1158/1538-7445.AM2023-6513
Published: 04 April 2023
View articletitled, Abstract 6513: Single cell and spatial profiling reveal molecular and immune evolution from precancers to invasive lung adenocarcinomas in genetic and carcinogen-induced mouse models
Journal Articles

Abstract 3406: Comprehensive genomic analysis of brain metastases from multiple cancer types

Free
Kazutaka Fukumura, Xizeng Mao, Xingzhi Song, Grant M. Fischer, Jie Yang, Erik P. Sulman, Michael A. Davies, Jianhua Zhang, Jason T. Huse
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3406.
https://doi.org/10.1158/1538-7445.AM2019-3406
Published: 01 July 2019
View articletitled, Abstract 3406: Comprehensive genomic analysis of brain metastases from multiple cancer types
Journal Articles

Abstract 2725: The single-cell atlas of driver mutations in acute myeloid leukemia

Free
Kiyomi Morita, Feng Wang, Katharina Jahn, Yuanqing Yan, Robert Durruthy-Durruthy, Anup Parikh, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur Patel, Carlos Bueso-Ramos, Courtney DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge Cortes, Marina Konopleva, Guillermo Garcia-Manero, Hagop Kantarjian, Dennis J. Eastburn, P Andrew Futreal, Niko Beerenwinkel, Koichi Takahashi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2725.
https://doi.org/10.1158/1538-7445.AM2019-2725
Published: 01 July 2019
View articletitled, Abstract 2725: The single-cell atlas of driver mutations in acute myeloid leukemia
Journal Articles

Abstract 5377: Tracking genomic and epigenomic evolution from preneoplastic lesions to lung adenocarcinoma by multiregion sequencing

Free
Xin Hu, Junya Fujimoto, Lisha Ying, Runzhe Chen, Marcos Roberto Estecio, Chi-Wan Chow, Jaime Rodriguez Canales, Xingzhi Song, Xizeng Mao, Paul Scheet, Humam Kadara, Edwin R. Parra Cuentas Cuentas, Carmen Behrens, Chang-Jiun Wu, J. Jack Lee, Mara Antonoff, Ara A Vaporciyan, Stephen Swisher, Jianhua zhang, John Heymach, Waun Ki Hong, Ignacio I. Wistuba, Wenyong Sun, Jinlin Hu, P. Andrew Futreal, Dan Su, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5377.
https://doi.org/10.1158/1538-7445.AM2018-5377
Published: 01 July 2018
View articletitled, Abstract 5377: Tracking genomic and epigenomic evolution from preneoplastic lesions to lung adenocarcinoma by multiregion sequencing
Journal Articles

Abstract 213: Exome sequencing of paired primary and relapsed small cell lung cancers reveals increased copy number aberration complexity to be associated with disease relapse

Free
Marcelo V. Negrao, Ming Tang, Ying Jin, Yamei Chen, Xiao Hu, Huarong Tang, Haimiao Xu, Kelly Quek, Jianhua Zhang, Xizeng Mao, Xingzhi Song, John V. Heymach, Ignacio Wistuba, Lauren A. Byers, Bonnie S. Glisson, Andrew Futreal, Ming Chen, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 213.
https://doi.org/10.1158/1538-7445.AM2018-213
Published: 01 July 2018
View articletitled, Abstract 213: Exome sequencing of paired primary and relapsed small cell lung cancers reveals increased copy number aberration complexity to be associated with disease relapse
Journal Articles

Abstract 156: Integrated exome and transcriptome sequencing of primary lung cancers and paired distant metastases

Free
Jianjun Zhang, Chia-Chin Wu, Jianhua Zhang, Junya Fujimoto, Xingzhi Song, Xizeng Mao, Huadong Sun, Sahil Seth, Rebecca Thornton, Marcus Coyle, Latasha Little, Curtis Gumbs, Carmen Behrens, Chi-Wan Chow, Erik Sulman, Ganesh Rao, Stephen Swisher, Ignacio Wistuba, John Heymach, Andrew Futreal, Daniel Gomez
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 156.
https://doi.org/10.1158/1538-7445.AM2016-156
Published: 15 July 2016
View articletitled, Abstract 156: Integrated exome and transcriptome sequencing of primary lung cancers and paired distant metastases
Journal Articles

Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Free
Haven R. Garber, Hannah Beird, Yu Cao, Jianhua Zhang, Rachel Sargent, Pei Lin, Sahil Seth, Xingzhi Song, Huandong Sun, Xizeng Mao, Lisa St John, Karen Clise-Dwyer, Gheath Alatrash, P. Andrew Futreal, Jeffrey J. Molldrem
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-222.
https://doi.org/10.1158/1538-7445.AM2015-LB-222
Published: 01 August 2015
View articletitled, Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion
Journal Articles

Abstract 2982: Genome sequencing reveals the multicentric nature of multiple synchronous lung adenocarcinomas

Free
Jianjun Zhang, Yu Liu, Lin Li, Jianhua Zhang, Guangliang Yin, Dongmei Lin, Xiangyang Liu, Hannah Cheung, Sahil Seth, Xingzhi Song, Xizeng Mao, Jiexin Zhang, Shujun Cheng, Andrew Futreal, Yanning Gao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2982.
https://doi.org/10.1158/1538-7445.AM2015-2982
Published: 01 August 2015
View articletitled, Abstract 2982: Genome sequencing reveals the multicentric nature of multiple synchronous lung adenocarcinomas
Journal Articles

Abstract 2841: A co-clinical assessment of patterns of BRAF inhibitor resistance

Free
Lawrence N. Kwong, Genevieve Boland, Dennie Frederick, Timothy Helms, Ahmad Akid, John Miller, Shan Jiang, Zachary Cooper, Xingzhi Song, Sahil Seth, Jennifer Kamara, Alexei Protopopov, Gordon Mills, Keith Flaherty, Jennifer Wargo, Lynda Chin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2841.
https://doi.org/10.1158/1538-7445.AM2015-2841
Published: 01 August 2015
View articletitled, Abstract 2841: A co-clinical assessment of patterns of BRAF inhibitor resistance