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Journal Articles

Abstract 3203: Extravasation and metastasis dynamics are cytoplasmically controlled by the epitranscriptome

Olivia R. Grafinger, Gobi Thillainadesan, Boyang Su, Yulin Mo, Xin Xu, Sara Mar, Minzhi Sheng, Sumaitha Al Islam, Jennifer Geddes-McAllister, Marc G. Coppolino, Hansen H. He, Gang Zheng, Katarzyna J. Jerzak, Hon S. Leong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3203.
https://doi.org/10.1158/1538-7445.AM2024-3203
Published: 22 March 2024
View article titled, Abstract 3203: Extravasation and metastasis dynamics are cytoplasmically controlled by the epitranscriptome
Journal Articles

Abstract 5400: Predicting disease progression in inoperable localized NSCLC patients using cfDNA fragmentomics assay

Yin Yang, Tao Zhang, Jingbo Wang, Jianyang Wang, Wanxiangfu Tang, Hua Bao, Haimeng Tang, Xue Wu, Yang Shao, Xin Wang, Yuqi Wu, Linfang Wu, Xin Xu, Kunpeng Xu, Jingjing Zhao, Luhua Wang, Nan Bi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5400.
https://doi.org/10.1158/1538-7445.AM2023-5400
Published: 04 April 2023
View article titled, Abstract 5400: Predicting disease progression in inoperable localized NSCLC patients using cfDNA fragmentomics assay
Journal Articles

Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer

Jiao Wang, Qiong Huang, Xingbin Hu, Shuyi Zhang, Yu Jiang, Guangyu Yao, Kongzhen Hu, Xin Xu, Bishan Liang, Qijing Wu, Zhenfeng Ma, Yawen Wang, Chunlin Wang, Zhenzhen Wu, Xiaoxiang Rong, Wangjun Liao, Min Shi
Journal: Cancer Research
Cancer Res (2022) 82 (8): 1503–1517.
https://doi.org/10.1158/0008-5472.CAN-21-1820
Published: 15 April 2022
View article titled, Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer
Open the PDF for Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

ANGPTL4-Mediated Promotion of Glycolysis Facilitates the Colonization of Fusobacterium nucleatum in Colorectal Cancer

Xin Zheng, Rui Liu, Chenchen Zhou, Haopeng Yu, Wanyi Luo, Jianhui Zhu, Jiaxin Liu, Zhe Zhang, Na Xie, Xian Peng, Xin Xu, Lei Cheng, Quan Yuan, Canhua Huang, Xuedong Zhou
Journal: Cancer Research
Cancer Res (2021) 81 (24): 6157–6170.
https://doi.org/10.1158/0008-5472.CAN-21-2273
Published: 15 December 2021
View article titled, ANGPTL4-Mediated Promotion of Glycolysis Facilitates the Colonization of <em>Fusobacterium nucleatum</em> in Colorectal Cancer
Open the PDF for ANGPTL4-Mediated Promotion of Glycolysis Facilitates the Colonization of <em>Fusobacterium nucleatum</em> in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3555: TREM2 is upregulated and plays oncogenic role in gastric cancer

Yulong Zheng, Lihua Jiang, Cheng Xiao, Nong Xu, Qiqi Gao, Yinan Yao, Yongxian Hu, Yun Sun, Xin Xu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3555.
https://doi.org/10.1158/1538-7445.AM2018-3555
Published: 01 July 2018
View article titled, Abstract 3555: TREM2 is upregulated and plays oncogenic role in gastric cancer
Journal Articles

Abstract 891: Annexin A2 (ANXA2) promotes migration and invasion of esophageal cancer cells via stabilizing c-Myc and promoting HIF-1α transcription

Sai Ma, Yan-Yi Jiang, Li-Fei Wu, Jia-Jie Hao, Yu Zhang, Xin Xu, Yan Cai, Ming-Rong Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 891.
https://doi.org/10.1158/1538-7445.AM2017-891
Published: 01 July 2017
View article titled, Abstract 891: Annexin A2 (ANXA2) promotes migration and invasion of esophageal cancer cells via stabilizing c-Myc and promoting HIF-1α transcription
Journal Articles

Abstract 605: Potency of Gp96-Ig/Fc-OX40L cell-based combination vaccine in cancer immunotherapy

Xin Xu, Louise E. Gonzalez, George J. Fromm, Suresh de Silva, Louise Giffin, Jason Rose, Taylor H. Schreiber
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 605.
https://doi.org/10.1158/1538-7445.AM2017-605
Published: 01 July 2017
View article titled, Abstract 605: Potency of Gp96-Ig/Fc-OX40L cell-based combination vaccine in cancer immunotherapy
Journal Articles

Abstract 1168: Efficacy of the IRAK4 inhibitor CA-4948 in patient-derived xenograft models of diffuse large B cell lymphoma

Robert N. Booher, Maria Elena Samson, Guang-Xin Xu, Hongsheng Cheng, David P. Tuck
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1168.
https://doi.org/10.1158/1538-7445.AM2017-1168
Published: 01 July 2017
View article titled, Abstract 1168: Efficacy of the IRAK4 inhibitor CA-4948 in patient-derived xenograft models of diffuse large B cell lymphoma
Journal Articles

Abstract 1405: Vesigenurtacel-L stimulates tumor infiltration of unique polyclonal T cell clones in non-muscle invasive bladder cancer patients

Taylor H. Schreiber, George Fromm, Xin Xu, Eric Yusko, Brandon Early, Melissa Price
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1405.
https://doi.org/10.1158/1538-7445.AM2016-1405
Published: 15 July 2016
View article titled, Abstract 1405: Vesigenurtacel-L stimulates tumor infiltration of unique polyclonal T cell clones in non-muscle invasive bladder cancer patients
Journal Articles

Effective Cancer Vaccine Platform Based on Attenuated Salmonella and a Type III Secretion System

Xin Xu, Wael A.H. Hegazy, Linjie Guo, Xiuhua Gao, Amy N. Courtney, Suhrab Kurbanov, Daofeng Liu, Gengwen Tian, Edwin R. Manuel, Don J. Diamond, Michael Hensel, Leonid S. Metelitsa
Journal: Cancer Research
Cancer Res (2014) 74 (21): 6260–6270.
https://doi.org/10.1158/0008-5472.CAN-14-1169
Published: 30 October 2014
View article titled, Effective Cancer Vaccine Platform Based on Attenuated <em>Salmonella</em> and a Type III Secretion System
Open the PDF for Effective Cancer Vaccine Platform Based on Attenuated <em>Salmonella</em> and a Type III Secretion System in another window
Includes: Supplementary data
Journal Articles

Rat Mcs1b Is Concordant to the Genome-Wide Association-Identified Breast Cancer Risk Locus at Human 5q11.2 and MIER3 is a Candidate Cancer Susceptibility Gene

Aaron D. denDekker, Xin Xu, M. Derek Vaughn, Aaron H. Puckett, Louis L. Gardner, Courtney J. Lambring, Lucas Deschenes, David J. Samuelson
Journal: Cancer Research
Cancer Res (2012) 72 (22): 6002–6012.
https://doi.org/10.1158/0008-5472.CAN-12-0748
Published: 14 November 2012
View article titled, Rat <em>Mcs1b</em> Is Concordant to the Genome-Wide Association-Identified Breast Cancer Risk Locus at Human <em>5q11.2</em> and <em>MIER3</em> is a Candidate Cancer Susceptibility Gene
Open the PDF for Rat <em>Mcs1b</em> Is Concordant to the Genome-Wide Association-Identified Breast Cancer Risk Locus at Human <em>5q11.2</em> and <em>MIER3</em> is a Candidate Cancer Susceptibility Gene in another window
Includes: Supplementary data
Journal Articles

Abstract 3744: Antitumor activity of CUDC-907, a dual PI3K and HDAC inhibitor, in hematological cancer models

Bao Rudi, Dagong Wang, Hui Qu, Ling Yin, Brian Zifcak, Steven DellaRocca, Guang-Xin Xu, Mylissa Borek, Maria Samson, Ruzanna Atoyan, Anne Poli, Jing Wang, Hai-Xaio Zhai, Cheng-Jung Lai, Carmen Pepicelli, Xiong Cai, Changgeng Qian
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3744.
https://doi.org/10.1158/1538-7445.AM2012-3744
Published: 15 April 2012
View article titled, Abstract 3744: Antitumor activity of CUDC-907, a dual PI3K and HDAC inhibitor, in hematological cancer models
Journal Articles

Abstract 3249: Design and synthesis of imidazopyridine derivatives as novel HSP90 inhibitors for the treatment of cancer

Xiong Cai, Hai-Xiao Zhai, Jing Wang, Maria Samson, Ruzanna Atoyan, Jeffrey Forrester, Hui Qu, Ling Yin, Dagong Wang, Brian Zifcak, Steven DellaRocca, Guang-Xin Xu, Cheng-Jung Lai, Rudi Bao, Marie-Paule Simonin, Mitchell Keegan, Carmen V. Pepicelli, Changgeng Qian
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3249.
https://doi.org/10.1158/1538-7445.AM2011-3249
Published: 15 April 2011
View article titled, Abstract 3249: Design and synthesis of imidazopyridine derivatives as novel HSP90 inhibitors for the treatment of cancer
Journal Articles

Abstract 2615: Antitumor activity of a dual PI3K and HDAC inhibitor in hematologic cancer models

Rudi Bao, Dagong Wang, Hui Qu, Ling Yin, Guang-Xin Xu, Steven DellaRocca, Mylissa Borek, Ruzanna Atoyan, Jeffrey Forrester, Maria Samson, Jing Wang, Hai-Xaio Zhai, Mendy Chan, Cheng-Jung Lai, Xiong Cai, Changgeng Qian
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2615.
https://doi.org/10.1158/1538-7445.AM2011-2615
Published: 15 April 2011
View article titled, Abstract 2615: Antitumor activity of a dual PI3K and HDAC inhibitor in hematologic cancer models
Journal Articles

CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity

Cheng-Jung Lai, Rudi Bao, Xu Tao, Jing Wang, Ruzanna Atoyan, Hui Qu, Da-Gong Wang, Ling Yin, Maria Samson, Jeffrey Forrester, Brian Zifcak, Guang-Xin Xu, Steven DellaRocca, Hai-Xiao Zhai, Xiong Cai, William E. Munger, Mitchell Keegan, Carmen V. Pepicelli, Changgeng Qian
Journal: Cancer Research
Cancer Res (2010) 70 (9): 3647–3656.
https://doi.org/10.1158/0008-5472.CAN-09-3360
Published: 28 April 2010
View article titled, CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity
Open the PDF for CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity in another window
Includes: Supplementary data
Journal Articles

Abstract 4469: Antitumor activity of a single small molecule agent targeting Pi3K/mTor and HDAC

Rudi Bao, Cheng-Jung Lai, Dagong Wang, Hui Qu, Ling Yin, Brian Zifcak, Xu Tao, Jing Wang, Hai-Xiao Zhai, Guang-Xin Xu, Mylissa Borek, Ruzanna Atoyan, Maria Samson, Jeffrey Forrester, Steven Dellarocca, Xiong Cai, Changgeng Qian
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4469.
https://doi.org/10.1158/1538-7445.AM10-4469
Published: 15 April 2010
View article titled, Abstract 4469: Antitumor activity of a single small molecule agent targeting Pi3K/mTor and HDAC
Journal Articles

Abstract 3392: Heat shock protein 27 increases metastasis of human head and neck squamous cancer cells in vitro

Zhenkun Zhu, Xin Xu, Yanke Yu, Martin Graham, Gangli Liu, Mark Prince, Thomas Carey, Duxin Sun
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3392.
https://doi.org/10.1158/1538-7445.AM10-3392
Published: 15 April 2010
View article titled, Abstract 3392: Heat shock protein 27 increases metastasis of human head and neck squamous cancer cells <em>in vitro</em>
Journal Articles

Abstract #4689: A novel tumor-specific HSP90 inhibitor with long lasting biological activity

Jing Wang, Xu Tao, Jeffrey Forrester, Ruzanna Atoyan, Maria Samson, Rudi Bao, Dagong Wang, Hui Qu, Ling Yin, Brain Zifcak, Changgeng Qian, Guang-Xin Xu, Steven DellaRocca, Xiong Cai, Hai-Xiao Zhai, Cheng-Jung Lai
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4689.
Published: 01 May 2009
View article titled, Abstract #4689: A novel tumor-specific HSP90 inhibitor with long lasting biological activity
Journal Articles

Abstract #1922: Antitumor activity of CUDC-305, a novel oral HSP90 inhibitor, in solid and hematological tumor xenograft models

Rudi Bao, Cheng-Jung Lai, Hui Qu, Dagong Wang, Brian Zifcak, Lin Yin, Xu Tao, Hai-Xiao Zhai, Guang-Xin Xu, Ruzanna Atoyan, Maria Samson, Jing Wang, Jeffrey Forrester, Steven DellaRocca, Xiong Cai, Changgeng Qian
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1922.
Published: 01 May 2009
View article titled, Abstract #1922: Antitumor activity of CUDC-305, a novel oral HSP90 inhibitor, in solid and hematological tumor xenograft models
Journal Articles

Cyclin-Dependent Kinase 2–Dependent Phosphorylation of ATRIP Regulates the G2-M Checkpoint Response to DNA Damage

Jeremy S. Myers, Runxiang Zhao, Xin Xu, Amy-Joan L. Ham, David Cortez
Journal: Cancer Research
Cancer Res (2007) 67 (14): 6685–6690.
https://doi.org/10.1158/0008-5472.CAN-07-0495
Published: 17 July 2007
View article titled, Cyclin-Dependent Kinase 2–Dependent Phosphorylation of ATRIP Regulates the G<sub>2</sub>-M Checkpoint Response to DNA Damage
Open the PDF for Cyclin-Dependent Kinase 2–Dependent Phosphorylation of ATRIP Regulates the G<sub>2</sub>-M Checkpoint Response to DNA Damage in another window