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Journal Articles

PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT

Wenchao Zhang, Wei Li, Chi Yin, Chengyao Feng, Binfeng Liu, Haodong Xu, Xin Jin, Chao Tu, Zhihong Li
Journal: Cancer Research
Cancer Res (2024) 84 (17): 2873–2887.
https://doi.org/10.1158/0008-5472.CAN-24-0163
Published: 04 September 2024
View article titled, PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT
Open the PDF for PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT in another window
Includes: Supplementary data
Journal Articles

CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer

Wei Li, Feng Guo, Ruijiang Zeng, Huaiyuan Liang, Yinhuai Wang, Wei Xiong, Heshui Wu, Chunguang Yang, Xin Jin
Journal: Cancer Research
Cancer Res (2024) 84 (16): 2588–2606.
https://doi.org/10.1158/0008-5472.CAN-23-3704
Published: 15 August 2024
View article titled, CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer
Open the PDF for CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

Yan Sun, Liang Zhu, Pian Liu, Huan Zhang, Feng Guo, Xin Jin
Journal: Cancer Research
Cancer Res (2023) 83 (12): 2034–2051.
https://doi.org/10.1158/0008-5472.CAN-22-3105
Published: 15 June 2023
View article titled, ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma
Open the PDF for ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors

Zhenlin Huang, Xiang Li, Bo Tang, Hao Li, Jianong Zhang, Rui Sun, Jian Ma, Yunqian Pan, Binyuan Yan, Yingke Zhou, Donglin Ding, Yuqian Yan, Rafael Jimenez, Jacob J. Orme, Xin Jin, Jinjian Yang, Haojie Huang, Zhankui Jia
Journal: Cancer Research
Cancer Res (2023) 83 (6): 875–889.
https://doi.org/10.1158/0008-5472.CAN-22-0264
Published: 15 March 2023
View article titled, SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors
Open the PDF for SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors in another window
Includes: Supplementary data
Journal Articles

Abstract 3088: The efficient utilization of paracrine support from established cell lines for breast/ovarian cancer model generation

Rebecca Deasy, Xin Jin, Pierre Michel Jean Beltran, Adel Atari, Madison Liistro, Cheryl Thompson, Stefanie Avril, Julie Boerner, Payal Pradhan, Samuel Klempner, Keith Ligon, William Sellers, Steven Carr, Todd Golub, Yuen-Yi (Moony) Tseng
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3088.
https://doi.org/10.1158/1538-7445.AM2022-3088
Published: 15 June 2022
View article titled, Abstract 3088: The efficient utilization of paracrine support from established cell lines for breast/ovarian cancer model generation
Journal Articles

Abstract NG10: A metastasis map of human cancer cell lines

Xin Jin, Zelalem Demere, Karthik Nair, Ahmed Ali, Gino B. Ferraro, Ted Natoli, Amy Deik, Lia Petronio, Andrew A. Tang, Cong Zhu, Li Wang, Danny Rosenberg, Vamsi Mangena, Jennifer Roth, Kwanghun Chung, Rakesh K. Jain, Clary B. Clish, Matthew G. Vander Heiden, Todd R. Golub
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): NG10.
https://doi.org/10.1158/1538-7445.AM2021-NG10
Published: 01 July 2021
View article titled, Abstract NG10: A metastasis map of human cancer cell lines
Journal Articles

Abstract 90: Fatty acid synthesis is required for breast cancer brain metastasis

Gino B. Ferraro, Ahmed Ali, Alba Luengo, David P. Kodack, Amy Deik, Keene L. Abbott, Divya Bezwada, Landry Blanc, Brendan Prideaux, Xin Jin, Jessica M. Possada, Jiang Chen, Christopher R. Chin, Zohreh Amoozgar, Raphael Ferreira, Ivy Chen, Kamila Naxerova, Christopher Ng, Anna M. Westermark, Mark Duquette, Sylvie Roberge, Costas A. Lyssiotis, Dan G. Duda, Todd R. Golub, Shawn M. Davidson, Dai Fukumura, Véronique A. Dartois, Clary B. Clish, Matthew G. Vander Heiden, Rakesh K. Jain
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 90.
https://doi.org/10.1158/1538-7445.AM2021-90
Published: 01 July 2021
View article titled, Abstract 90: Fatty acid synthesis is required for breast cancer brain metastasis
Journal Articles

HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer

Yingke Zhou, Xin Jin, Jian Ma, Donglin Ding, Zhenlin Huang, Haoyue Sheng, Yuqian Yan, Yunqian Pan, Ting Wei, Liguo Wang, Heshui Wu, Haojie Huang
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1486–1499.
https://doi.org/10.1158/0008-5472.CAN-20-2828
Published: 15 March 2021
View article titled, HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer
Open the PDF for HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PO-031: MetMap: A map of metastatic potential of human cancer cell lines

Xin Jin, Zelalem Demere, Karthik Nair, Ahmed Ali, Gino B. Ferraro, Ted Natoli, Amy Deik, Lia Petronio, Andrew A. Tang, Cong Zhu, Li Wang, Danny Rosenberg, Vamsi Mangena, Jennifer Roth, Kwanghun Chung, Rakesh K. Jain, Clary B. Clish, Matthew G. Vander Heiden, Todd R. Golub
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-031.
https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-031
Published: 02 December 2020
View article titled, Abstract PO-031: MetMap: A map of metastatic potential of human cancer cell lines
Journal Articles

Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1–MAPK Interaction

Xin Jin, Yunqian Pan, Liguo Wang, Tao Ma, Lizhi Zhang, Amy H. Tang, Daniel D. Billadeau, Heshui Wu, Haojie Huang
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4328–4341.
https://doi.org/10.1158/0008-5472.CAN-16-3143
Published: 14 August 2017
View article titled, Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1–MAPK Interaction
Open the PDF for Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1–MAPK Interaction in another window
Includes: Supplementary data
Journal Articles

Abstract 2683: The landscape of chromosomal aberrations in mouse models of breast cancer reveals driver-specific routes to tumor development

Uri Ben-David, Gavin Ha, Prasidda Khadka, Xin Jin, Lude Franke, Todd R. Golub
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2683.
https://doi.org/10.1158/1538-7445.AM2016-2683
Published: 15 July 2016
View article titled, Abstract 2683: The landscape of chromosomal aberrations in mouse models of breast cancer reveals driver-specific routes to tumor development
Journal Articles

Abstract PR06: Metastatic latency and immune evasion mediated by autocrine WNT inhibition

Srinivas Malladi, Danilo G. Macalinao, Xin Jin, Lan He, Joan Massague
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): PR06.
https://doi.org/10.1158/1538-7445.TUMMET15-PR06
Published: 26 May 2016
View article titled, Abstract PR06: Metastatic latency and immune evasion mediated by autocrine WNT inhibition
Journal Articles

Abstract A44: Metastatic latency and immune evasion mediated by autocrine WNT inhibition

Srinivas Malladi, Danilo G. Macalinao, Xin Jin, Lan He, Joan Massague
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): A44.
https://doi.org/10.1158/1538-7445.TUMMET15-A44
Published: 26 May 2016
View article titled, Abstract A44: Metastatic latency and immune evasion mediated by autocrine WNT inhibition
Journal Articles

Abstract C8: Bone metastasis seed preselection by the primary tumor stroma

Xiang Zhang, Xin Jin, Srinivas Malladi, Yong Wen, Edi Brogi, Joan Massague
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): C8.
https://doi.org/10.1158/1538-7445.TIM2013-C8
Published: 01 May 2014
View article titled, Abstract C8: Bone metastasis seed preselection by the primary tumor stroma