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Journal Articles

Abstract P1-08-19: Utilising artificial intelligence (AI) for analysing multiplex genomic and magnetic resonance imaging (MRI) data to develop multimodality predictive system for personalised neoadjuvant treatment of breast cancer (BC)

Tarek Ma Abdel-Fatah, Graham Ball, Xin Chen, Dalia Mehaisi, Elisabetta Giannotti, Dorothee Auer, Jayakumar Vadakekolathu, Ruizhe Li, Graham Pockley, Stephen Chan
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-19.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-08-19
Published: 15 February 2022
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Journal Articles

Abstract 43: Discovery of ARV-110, a first in class androgen receptor degrading PROTAC for the treatment of men with metastatic castration resistant prostate cancer

Lawrence B. Snyder, Taavi K. Neklesa, Xin Chen, Hanqing Dong, Caterina Ferraro, Deborah A. Gordon, Jennifer Macaluso, Jennifer Pizzano, Jing Wang, Ryan R. Willard, Nicholas Vitale, Ron Peck, Marcia Dougan Moore, Craig M. Crews, John Houston, Andrew P. Crew, Ian Taylor
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 43.
DOI: https://doi.org/10.1158/1538-7445.AM2021-43
Published: 01 July 2021
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Journal Articles

Abstract 641: Clinical assessment of the bioavailability of venetoclax tablet and powder formulations

Mohamed Badawi, Bo Tong, Xin Chen, Tammy Palenski, Su Young Kim, Divya Samineni, David Hoffman, Rajeev Menon, Ahmed Hamed Salem
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 641.
DOI: https://doi.org/10.1158/1538-7445.AM2021-641
Published: 01 July 2021
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Abstract 1854: A Fc-competent anti-human TIGIT blocking antibody BGB-A1217 elicits strong immune responses and potent anti-tumor efficacy in pre-clinical models

Xin Chen, Liu Xue, Xiao Ding, Qi Liu, Jing Zhang, Lei Jiang, Sha Liu, Hongjia Hou, Qing Zhu, Bin Jiang, Lijie Zhang, Xiaosui Zhou, Jie Ma, Yucheng Li, Wei Jin, Min Wei, Zhirong Shen, Mike Liu, Kang Li, Tong Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1854.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1854
Published: 01 July 2021
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Journal Articles

MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo

Jing Yang, Aiwen Jin, Jing Han, Xin Chen, Junnian Zheng, Yanping Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (4): 898–909.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0790
Published: 15 February 2021
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Abstract 5687: Selective, chemically-induced degradation of BRM (SMARCA2) enables in vivo efficacy in BRG1 (SMARCA4)-deficient xenograft tumor models

Michael Berlin, Jennifer Cantley, Jing Wang, Mark Bookbinder, Gregory Cadelina, Emily Chan, Huifen Chen, Xin Chen, Kim Davenport, Tharu Fernando, Debbie Gordon, Brian Hamman, Roy Haskell, Alexey Ishchenko, Donald S. Kirkpatrick, Jonathan Maher, Mark Merchant, John Moffat, Alicia Morgan, An Nguyen, Jennifer Pizzano, Connor Quinn, Christopher M. Rose, Emma Rousseau, Vijay Sethuraman, Leanna Staben, Catherine Wilson, Xiaofen Ye, Fabio Broccatelli, Robert Yauch, Peter S. Dragovich
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5687.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5687
Published: 15 August 2020
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Journal Articles

Abstract P3-07-02: Developing a robust multidimensional molecular, pathological and radiological prognostic index (MPRPI) to evaluate the response to neoadjuvant chemotherapy (NACT) and predict clinical outcome of breast cancer (BC)

Tarek M. a. Abdel-Fatah, Xin Chen, Ruizhe Li, Elisabetta Giannotti, Dorothee Auer, Jennifer Walker, Jun Lim, A. Graham Pockley, Graham Ball, Emad Rakhah, Ian Ellis, Arlene Chan, Stephen Chan
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-07-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P3-07-02
Published: 15 February 2020
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Journal Articles

SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial–Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model

Meng Xu, Jingxiao Wang, Zhong Xu, Rong Li, Pan Wang, Runze Shang, Antonio Cigliano, Silvia Ribback, Antonio Solinas, Giovanni Mario Pes, Katja Evert, Haichuan Wang, Xinhua Song, Shu Zhang, Li Che, Rosa Maria Pascale, Diego Francesco Calvisi, Qingguang Liu, Xin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5563–5574.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-3750
Published: 01 November 2019
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Includes: Supplementary data
Journal Articles

Abstract 3307: Real-world outcomes of first-line pembrolizumab monotherapy for PD-L1-positive (TPS ≥50%) metastatic non-small cell lung cancer (NSCLC)

Vamsidhar Velcheti, Sheenu Chandwani, Xin Chen, M. Catherine Pietanza, Thomas Burke
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3307.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3307
Published: 01 July 2019
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Journal Articles

Abstract 1564: Polymorphisms in nucleotide excision repair genes were associated with the survival of post-operative oral squamous cell carcinoma patients treated with adjuvant concurrent chemoradiotherapy

Chih-Ching Yeh, Thomas Senghore, Huei-Tzu Chien, Wen-Chang Wang, You-Xin Chen, Chi-Kuan Young, Shiang-Fu Huang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1564.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1564
Published: 01 July 2019
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Journal Articles

Abstract 1721: FOXO1, a downstream substrate of AKT, function as tumor suppressor in HCC carcinogenesis

Shu Zhang, Xin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1721.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1721
Published: 01 July 2019
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Journal Articles

CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder

Xin Chen, Jia-Xing Zhang, Jun-Hang Luo, Song Wu, Gang-Jun Yuan, Ning-Fang Ma, Yong Feng, Mu-Yan Cai, Ri-Xin Chen, Jun Lu, Li-Juan Jiang, Jie-Wei Chen, Xiao-Han Jin, Hai-Liang Liu, Wei Chen, Xin-Yuan Guan, Tie-Bang Kang, Fang-Jian Zhou, Dan Xie
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5848–5862.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-0822
Published: 15 October 2018
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Includes: Supplementary data
Journal Articles

Abstract LB-097: Linking prostate cancer cell AR heterogeneity to distinct castration and Enzalutamide responses

Qiuhui Li, Xin Chen, Qu Deng, Hsueh-Ping Chao, Amanda Tracz, Jason Kirk, Ruizhe Zhao, Kiera Rycaj, Dean G Tang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-097.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-097
Published: 01 July 2018
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Abstract LB-288: A highly selective small molecule CSF-1R inhibitor demonstrates strong immunomodulatory activity in syngeneic models

Shuqun Yang, Baowei Zhao, Mingming Zhang, Yuan Zhao, Xin Chen, Lei Zhang, Hongping Yu, Zhui Chen, Yaochang Xu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-288.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-288
Published: 01 July 2018
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Abstract 901: Antibody-mediated blockade of annexin A3 (ANXA3) synergistically enhances the efficacy of sorafenib and regorafenib for hepatocellular carcinoma

Man Tong, Noelia Che, Lei Zhou, Phillis W. Kau, Steve T. Luk, Xin Chen, Jin Ding, Terence K. Lee, Stephanie Ma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 901.
DOI: https://doi.org/10.1158/1538-7445.AM2018-901
Published: 01 July 2018
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Journal Articles

Abstract 5902: RNA sequencing analysis of taxane-resistant prostate cancer cells reveals potential candidate genes for therapeutic targeting

Christina K. Cajigas-Du Ross, Leanne Woods-Burnham, Joshua Ramirez, Xin Chen, Charles Wang, Carlos A. Casiano
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5902.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5902
Published: 01 July 2018
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Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities

Andrés Méndez-Lucas, Xiaolei Li, Junjie Hu, Li Che, Xinhua Song, Jiaoyuan Jia, Jingxiao Wang, Chencheng Xie, Paul C. Driscoll, Darjus F. Tschaharganeh, Diego F. Calvisi, Mariia Yuneva, Xin Chen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (16): 4355–4364.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0498
Published: 14 August 2017
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Includes: Supplementary data
Journal Articles

Abstract 4177: Anticancer agent Aminoflavone restores the expression of tumor suppressor miRNA 26a and inhibits putative stemness biomarker α6-integrin in Tamoxifen resistant cells

Petreena Campbell, Leah Rowland, Anna Opoku-Agyeman, Nichole Mavingire, Ubaldo Soto, Gayathri Nagaraj, Yonghong Zhang, Sean (Xin) Chen, Charles Wang, Eileen Brantley
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4177.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4177
Published: 01 July 2017
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Abstract 1903: Cancer stem cell vaccine significantly reduces local tumor relapse and prolongs survival in the adjuvant setting

Fei Liao, Yang yang Hu, Xin Chen, Alfed E Chang, Robert E Hollingsworth, Elaine Hurt, John Owen, Jeffrey S Moyer, Mark E.P Prince, Joel Whitfield, Yuxin Chu, Qibin Song, Max S Wicha, Qiao Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1903.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1903
Published: 01 July 2017
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Abstract 2243: Elucidating the mechanism of action of molecular iodine on breast cancer cells

Zack Xu, Xin Chen, Noymi Yam, kin Chan, Usha Nagavarapu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2243.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2243
Published: 01 July 2017
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