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Xihong Zhang
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Journal Articles

Abstract P2-26-13: Gene deletion of insulin receptor in MCF-7L breast cancer cells by CRISPR gene editing

Xihong Zhang, Marvis Monteiro, Douglas Yee
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-26-13.
https://doi.org/10.1158/1538-7445.SABCS22-P2-26-13
Published: 01 March 2023
View article titled, Abstract P2-26-13: Gene deletion of insulin receptor in MCF-7L breast cancer cells by CRISPR gene editing
Journal Articles

Abstract P2-03-02: Detection of insulin receptor isoforms by mass spectrometry in breast cancer

Xihong Zhang, LeeAnn Higgins, Todd Markowski, Tzu-Yi Yang, Jacob Wragge, Kevin Murray, Bruce Witthuhn, Albert Barrios, Douglas Yee
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-03-02.
https://doi.org/10.1158/1538-7445.SABCS21-P2-03-02
Published: 15 February 2022
View article titled, Abstract P2-03-02: Detection of insulin receptor isoforms by mass spectrometry in breast cancer
Journal Articles

Abstract P4-02-01: Targeting insulin receptor in estrogen receptor positive breast cancer

Jingran Cao, Lynsey M. Fettig, Kelly LaPara, Xihong Zhang, Sylaja Murikipudi, Andrea R. Delpero, Thomas M. Lancaster, Todd C. Zion, Douglas Yee
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-02-01.
https://doi.org/10.1158/1538-7445.SABCS21-P4-02-01
Published: 15 February 2022
View article titled, Abstract P4-02-01: Targeting insulin receptor in estrogen receptor positive breast cancer
Journal Articles

Abstract P1-21-05: A novel long-acting insulin for cancer therapy reduces xenograft tumor growth

Lynsey M Fettig, Xihong Zhang, Kelly LaPara, Sylaja Murikipudi, Andrea R Delpero, Thomas M Lancaster, Todd C Zion, Douglas Yee
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-21-05.
https://doi.org/10.1158/1538-7445.SABCS19-P1-21-05
Published: 15 February 2020
View article titled, Abstract P1-21-05: A novel long-acting insulin for cancer therapy reduces xenograft tumor growth
Journal Articles

Abstract P3-10-09: Gene deletion of IRS1 inhibited IGF-I, insulin and estradiol stimulated MCF-7L breast cancer cell growth

Xihong Zhang, Douglas Yee
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-10-09.
https://doi.org/10.1158/1538-7445.SABCS19-P3-10-09
Published: 15 February 2020
View article titled, Abstract P3-10-09: Gene deletion of IRS1 inhibited IGF-I, insulin and estradiol stimulated MCF-7L breast cancer cell growth
Journal Articles

Abstract 4406: Inducible knockdown of insulin receptor substrate I desensitizes ER alpha response to both agonist (estradiol) and antagonist (fulvestrant) in MCF-7L breast cancer cells

Xihong Zhang, Sidhant Varma, Douglas Yee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4406.
https://doi.org/10.1158/1538-7445.AM2016-4406
Published: 15 July 2016
View article titled, Abstract 4406: Inducible knockdown of insulin receptor substrate I desensitizes ER alpha response to both agonist (estradiol) and antagonist (fulvestrant) in MCF-7L breast cancer cells
Journal Articles

Abstract P6-12-05: Inducible suppression of insulin receptor substrate I inhibits IGF-I/insulin/estradiol dependent cell growth in MCF-7L breast cancer cells

Xihong Zhang, Sidhant Varma, Douglas Yee
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-12-05.
https://doi.org/10.1158/1538-7445.SABCS14-P6-12-05
Published: 01 May 2015
View article titled, Abstract P6-12-05: Inducible suppression of insulin receptor substrate I inhibits IGF-I/insulin/estradiol dependent cell growth in MCF-7L breast cancer cells
Journal Articles

Disruption of IGF signaling in melanoma cells inhibits growth, motility and invasion

Xihong Zhang, Cheryl L. Neudauer, Kelly S. Lapara, Rajeeva Singh, James B. McCarthy, Douglas Yee
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 773.
Published: 15 April 2006
View article titled, Disruption of IGF signaling in melanoma cells inhibits growth, motility and invasion
Journal Articles

Selective Activation of Insulin Receptor Substrate-1 and -2 in Pleural Mesothelioma Cells: Association with Distinct Malignant Phenotypes

Chuong D. Hoang, Xihong Zhang, Paul D. Scott, Tenner J. Guillaume, Michael A. Maddaus, Douglas Yee, Robert A. Kratzke
Journal: Cancer Research
Cancer Res (2004) 64 (20): 7479–7485.
https://doi.org/10.1158/0008-5472.CAN-04-1898
Published: 15 October 2004
View article titled, Selective Activation of Insulin Receptor Substrate-1 and -2 in Pleural Mesothelioma Cells: <subtitle>Association with Distinct Malignant Phenotypes</subtitle>
Open the PDF for Selective Activation of Insulin Receptor Substrate-1 and -2 in Pleural Mesothelioma Cells: <subtitle>Association with Distinct Malignant Phenotypes</subtitle> in another window
Journal Articles

Derangement of the IGF system in malignant mesothelioma: IGF-1 induces cell proliferation via insulin receptor substrate-1

Chuong D. Hoang, Xihong Zhang, Paul D. Scott, Michael A. Maddaus, Douglas Yee, Robert A. Kratzke
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1197–1198.
Published: 01 April 2004
View article titled, Derangement of the IGF system in malignant mesothelioma: IGF-1 induces cell proliferation via insulin receptor substrate-1
Journal Articles

Insulin-like Growth Factor Binding Protein-1 (IGFBP-1) Inhibits Breast Cancer Cell Motility

Xihong Zhang, Douglas Yee
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4369–4375.
Published: 01 August 2002
View article titled, Insulin-like Growth Factor Binding Protein-1 (IGFBP-1) Inhibits Breast Cancer Cell Motility
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