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Journal Articles

Abemaciclib Is Effective in Palbociclib-Resistant Hormone Receptor–Positive Metastatic Breast Cancers

Juliana Navarro-Yepes, Nicole M. Kettner, Xiayu Rao, Cassandra Santaella Bishop, Tuyen N. Bui, Hannah F. Wingate, Akshara Singareeka Raghavendra, Yan Wang, Jing Wang, Aysegul A. Sahin, Funda Meric-Bernstam, Kelly K. Hunt, Senthil Damodaran, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res OF1–OF20.
https://doi.org/10.1158/0008-5472.CAN-23-0705
Published: 11 September 2023
View article titled, Abemaciclib Is Effective in Palbociclib-Resistant Hormone Receptor–Positive Metastatic Breast Cancers
Open the PDF for Abemaciclib Is Effective in Palbociclib-Resistant Hormone Receptor–Positive Metastatic Breast Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 515: Single-cell transcriptomic analysis of HR+/HER2- breast cancer identifies gene signatures that predict outcomes of luminal A and B subtypes

Sofia Mastoraki, Jerome Lin, Xiayu Rao, Sophie R. Liu, Harsh Batra, Maria G. Raso, Edwin R. Parra Cuentas, Akshara S. Raghavendra, Komal S. Rasaputra, Min Yi, Jing Wang, Aysegul Sahin, Debasish Tripathy, Kelly K. Hunt, Nicholas E. Navin, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 515.
https://doi.org/10.1158/1538-7445.AM2022-515
Published: 15 June 2022
View article titled, Abstract 515: Single-cell transcriptomic analysis of HR+/HER2- breast cancer identifies gene signatures that predict outcomes of luminal A and B subtypes
Journal Articles

Abstract 1798: Mechanisms of acquired resistance to palbociclib reveals pathways of response to abemaciclib

Juliana Navarro-Yepes, Nicole M. Kettner, Tuyen Bui, Akshara S. Raghavendra, Xiayu Rao, Jing Wang, Aysegul Sahin, Senthil Damodaran, Debasish Tripathy, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1798.
https://doi.org/10.1158/1538-7445.AM2022-1798
Published: 15 June 2022
View article titled, Abstract 1798: Mechanisms of acquired resistance to palbociclib reveals pathways of response to abemaciclib
Journal Articles

Abstract 264: Neutrophil elastase (NE) inhibition enhances metastasis free survival by altering regulation of tumor intrinsic cytoskeletal and cellular adhesion pathways in murine breast cancer models

Amriti R. Lulla, Said Akli, Lucas D. Warma, Natalie W. Fowlkes, Kelly K. Hunt, Xiayu Rao, Jing Wang, Stephanie S. Watowich, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 264.
https://doi.org/10.1158/1538-7445.AM2022-264
Published: 15 June 2022
View article titled, Abstract 264: Neutrophil elastase (NE) inhibition enhances metastasis free survival by altering regulation of tumor intrinsic cytoskeletal and cellular adhesion pathways in murine breast cancer models
Journal Articles

Abstract 3107: Identifying therapeutic vulnerabilities in HR-positive, HER2-negative advanced breast cancer patient-derived xenograft models refractory to CDK4/6 inhibition

Nicole M. Kettner, Juliana Navarro-Yepes, Tuyen N. Bui, Xiayu Rao, Jing Wang, Funda Meric-Bernstam, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3107.
https://doi.org/10.1158/1538-7445.AM2022-3107
Published: 15 June 2022
View article titled, Abstract 3107: Identifying therapeutic vulnerabilities in HR-positive, HER2-negative advanced breast cancer patient-derived xenograft models refractory to CDK4/6 inhibition
Journal Articles

Abstract NG07: Cancer takes a nerve: Loss of p53 drives neuron reprogramming in head and neck cancer

Moran Amit, Hideaki Takahashi, Mihnea-Paul Dragomir, Simone Anfossi, Antje Lindemann, Frederico Netto-Glebber, Samantha Tam, Abdullah Osman, Erik Kuntsen, Curtis R. Pickering, Mei Zhao, Xiayu Rao, Jing Wang, Deborah A. Silverman, Carlos Caulin, Assaf Zinger, Ennio Tasciotti, Patrick Dougherty, Adel El-Naggar, George A. Calin, Jeffrey N. Myers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): NG07.
https://doi.org/10.1158/1538-7445.AM2021-NG07
Published: 01 July 2021
View article titled, Abstract NG07: Cancer takes a nerve: Loss of p53 drives neuron reprogramming in head and neck cancer
Journal Articles

Abstract 323: Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer

Nicole M. Kettner, Smruthi Vijayaraghavan, Merih Guray Durak, Tuyen Bui, Mehrnoosh Kohansal, Min Jin Ha, Bin Liu, Xiayu Rao, Jing Yang, Min Yi, Jason P. Carey, Xian Chen, T. Kris Eckols, Akshara S. Raghavendra, Nuhad K. Ibrahim, Meghan Karuturi, Stephanie S. Watowich, Aysegul A. Sahin, David J. Tweardy, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 323.
https://doi.org/10.1158/1538-7445.AM2019-323
Published: 01 July 2019
View article titled, Abstract 323: Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer
Journal Articles

Abstract 4942: Variations in HPV function are associated with patient outcome and identify new candidate therapeutic approaches

Frederico O. Gleber-Netto, Meng Gao, Xiayu Rao, Christopher P. Vellano, Joseph R. Marszalek, Jing Wang, Faye M. Johnson, Curtis R. Pickering
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4942.
https://doi.org/10.1158/1538-7445.AM2019-4942
Published: 01 July 2019
View article titled, Abstract 4942: Variations in HPV function are associated with patient outcome and identify new candidate therapeutic approaches
Journal Articles

Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties

Chenfei Huang, Shhyam Moorthy, Qiuli Li, Rami Saade, Jiping Wang, Xiayu Rao, Noriaki Tanaka, Jiexin Zhang, Lin Tang, Curtis R. Pickering, Patrick A. Zweidler-McKay, Abdullah A. Osman, Tong-Xin Xie, Eve Shinbrot, Liu Xi, David Wheeler, Adel K. El-Naggar, Jing Wang, Jeffrey N. Myers, Mitchell J. Frederick
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5506.
https://doi.org/10.1158/1538-7445.AM2018-5506
Published: 01 July 2018
View article titled, Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties
Journal Articles

Abstract 4621: Risk stratification and biomarker discovery in HPV-positive oropharynx squamous cell carcinoma determined by HPV and human gene expression profile associations

Frederico O. Gleber-Netto, Xiayu Rao, Kelly Erikson, Keiko Akagi, Faye M. Johnson, Jing Wang, Joseph Califano, Maura L. Gillison, Jeffrey N. Myers, Curtis R. Pickering
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4621.
https://doi.org/10.1158/1538-7445.AM2018-4621
Published: 01 July 2018
View article titled, Abstract 4621: Risk stratification and biomarker discovery in HPV-positive oropharynx squamous cell carcinoma determined by HPV and human gene expression profile associations
Journal Articles

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition

Mayur A. Gadhikar, Jiexin Zhang, Li Shen, Xiayu Rao, Jing Wang, Mei Zhao, Nene N. Kalu, Faye M. Johnson, Lauren A. Byers, John Heymach, Walter N. Hittelman, Durga Udayakumar, Raj K. Pandita, Tej K. Pandita, Curtis R. Pickering, Abena B. Redwood, Helen Piwnica-Worms, Katharina Schlacher, Mitchell J. Frederick, Jeffrey N. Myers
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (3): 781–797.
https://doi.org/10.1158/0008-5472.CAN-17-2802
Published: 31 January 2018
View article titled, <em>CDKN2A/p16</em> Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition
Open the PDF for <em>CDKN2A/p16</em> Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 5123: Multiplex in situ immunoprofiling and survival outcomes in non-small cell lung cancer

Steven H. Lin, James R. Mansfield, Xiayu Rao, Wen Jiang, Penny Fang, Kristin Roman, Chichung Wang, Ritsuko Komaki, Stephen Hahn, Stephen G. Swisher, Junya Fujimoto, Ignacio Wistuba, Jing Wang, Clifford C. Hoyt
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5123.
https://doi.org/10.1158/1538-7445.AM2016-5123
Published: 15 July 2016
View article titled, Abstract 5123: Multiplex in situ immunoprofiling and survival outcomes in non-small cell lung cancer
Journal Articles

Abstract 2592: Vitamin E forms and 13′-carboxychromanol, a long-chain metabolite of α-tocopherol, induce cell death by interrupting de novo sphingolipid synthesis in human cancer cells

Yumi Jang, Xiayu Rao, Qing Jiang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2592.
https://doi.org/10.1158/1538-7445.AM2012-2592
Published: 15 April 2012
View article titled, Abstract 2592: Vitamin E forms and 13′-carboxychromanol, a long-chain metabolite of α-tocopherol, induce cell death by interrupting <em>de novo</em> sphingolipid synthesis in human cancer cells
Journal Articles

Abstract 217: Vitamin E forms induce apoptosis, necrosis, and autophagy and caused accumulation of sphingolipid intermediates in human colon cancer cells

Xiayu Rao, Qing Jiang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 217.
https://doi.org/10.1158/1538-7445.AM10-217
Published: 15 April 2010
View article titled, Abstract 217: Vitamin E forms induce apoptosis, necrosis, and autophagy and caused accumulation of sphingolipid intermediates in human colon cancer cells