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Journal Articles

Abstract A064: Identifying cooperating genetic events contributing to disease progression in mutant p53-driven breast cancer

Rhiannon L Morrissey, Joy M McDaniel, Dhruv Chachad, Xiaoping Su, Patty Chau, Adel El-Naggar, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_1): A064.
https://doi.org/10.1158/1538-7445.ADVBC23-A064
Published: 01 February 2024
View articletitled, Abstract A064: Identifying cooperating genetic events contributing to disease progression in mutant p53-driven breast cancer
Journal Articles

Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma

Guillaume Davidson, Alexandra Helleux, Yann A. Vano, Véronique Lindner, Antonin Fattori, Marie Cerciat, Reza T. Elaidi, Virginie Verkarre, Cheng-Ming Sun, Christine Chevreau, Mostefa Bennamoun, Hervé Lang, Thibault Tricard, Wolf H. Fridman, Catherine Sautes-Fridman, Xiaoping Su, Damien Plassard, Celine Keime, Christelle Thibault-Carpentier, Philippe Barthelemy, Stéphane M. Oudard, Irwin Davidson, Gabriel G. Malouf
Journal: Cancer Research
Cancer Res (2023) 83 (17): 2952–2969.
https://doi.org/10.1158/0008-5472.CAN-22-3034
Published: 01 September 2023
View articletitled, Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma
Open the PDF for Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Unique Transcriptional Profiles Underlie Osteosarcomagenesis Driven by Different p53 Mutants

Dhruv Chachad, Lalit R. Patel, Carlos Vera Recio, Rasoul Pourebrahim, Elizabeth M. Whitley, Wenyi Wang, Xiaoping Su, An Xu, Dung-Fang Lee, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2023) 83 (14): 2297–2311.
https://doi.org/10.1158/0008-5472.CAN-22-3464
Published: 14 July 2023
View articletitled, Unique Transcriptional Profiles Underlie Osteosarcomagenesis Driven by Different p53 Mutants
Open the PDF for Unique Transcriptional Profiles Underlie Osteosarcomagenesis Driven by Different p53 Mutants in another window
Includes: Supplementary data
Journal Articles

Abstract 1342: Roles of mesenchymal-like tumour cells and myofibroblastic cancer-associated fibroblasts in progression and therapeutic response of clear-cell renal cell carcinoma

Alexandra Helleux, Guillaume Davidson, Yann A. Vano, Véronique Lindner, Antonin Fattori, Marie Cerciat, Reza T. Elaidi, Virginie Verkarre, Cheng-Ming Sun, Christine Chevreau, Mostefa Bennamoun, Hervé Lang, Thibault Tricard, Wolf H. Fridman, Catherine Sautes-Fridman, Xiaoping Su, Damien Plassard, Céline Keime, Christelle Thibault-Carpentier, Philippe Barthelemy, Stéphane Oudard, Irwin Davidson, Gabriel G. Malouf
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1342.
https://doi.org/10.1158/1538-7445.AM2023-1342
Published: 04 April 2023
View articletitled, Abstract 1342: Roles of mesenchymal-like tumour cells and myofibroblastic cancer-associated fibroblasts in progression and therapeutic response of clear-cell renal cell carcinoma
Journal Articles

Abstract P3-05-22: Serum S100A8/S100A9 levels are associated with increased risk of brain metastasis in patients with aggressive breast cancer

Emilly S. Villodre, Xiaoding Hu, Juhee Song, Kristen Gomez, Xiaoping Su, James Reuben, Naoto T. Ueno, Debu Tripathy, Savitri Krishnamurthy, Bisrat Debeb
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-05-22.
https://doi.org/10.1158/1538-7445.SABCS22-P3-05-22
Published: 01 March 2023
View articletitled, Abstract P3-05-22: Serum S100A8/S100A9 levels are associated with increased risk of brain metastasis in patients with aggressive breast cancer
Journal Articles

Abstract 3329: Efficacy of EGFR/PI3K signaling inhibition is enhanced with LSD1 inhibition in glioblastoma stem cell (GSC) models

Lea Stitzlein, Matthew Luetzen, Caitlin McCabe, Maninder Khosla, Melissa Singh, Xiaoping Su, Yue Lu, Joy Gumin, Frederick Lang, Christopher Whitehead, Judith Sebolt-Leopold, Joya Chandra
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3329.
https://doi.org/10.1158/1538-7445.AM2022-3329
Published: 15 June 2022
View articletitled, Abstract 3329: Efficacy of EGFR/PI3K signaling inhibition is enhanced with LSD1 inhibition in glioblastoma stem cell (GSC) models
Journal Articles

Abstract 829: p53 dimers elicit tumor suppressive activities through an altered metabolic program

Jovanka Gencel-Augusto, Xiaoping Su, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 829.
https://doi.org/10.1158/1538-7445.AM2022-829
Published: 15 June 2022
View articletitled, Abstract 829: p53 dimers elicit tumor suppressive activities through an altered metabolic program
Journal Articles

Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo

Shunbin Xiong, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun, Gilda Chau, Yuan Qi, Xiaoping Su, Elizabeth M. Whitley, Adel K. El-Naggar, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2022) 82 (10): 1926–1936.
https://doi.org/10.1158/0008-5472.CAN-21-3376
Published: 16 May 2022
View articletitled, Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo
Open the PDF for Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo in another window
Includes: Supplementary data
Journal Articles

Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer

Kurt W. Evans, Erkan Yuca, Stephen S. Scott, Ming Zhao, Natalia Paez Arango, Christian X. Cruz Pico, Turcin Saridogan, Maryam Shariati, Caleb A. Class, Christopher A. Bristow, Christopher P. Vellano, Xiaofeng Zheng, Ana Maria Gonzalez-Angulo, Xiaoping Su, Coya Tapia, Ken Chen, Argun Akcakanat, Bora Lim, Debu Tripathy, Timothy A. Yap, Maria Emilia Di Francesco, Giulio F. Draetta, Philip Jones, Timothy P. Heffernan, Joseph R. Marszalek, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5572–5581.
https://doi.org/10.1158/0008-5472.CAN-20-3242
Published: 01 November 2021
View articletitled, Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer
Open the PDF for Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4286: TGF-β signature is a therapeutic biomarker for combination immunotherapy for hepatocellular carcinoma

Jian Chen, Xiaoping Su
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4286.
https://doi.org/10.1158/1538-7445.AM2020-4286
Published: 15 August 2020
View articletitled, Abstract 4286: TGF-β signature is a therapeutic biomarker for combination immunotherapy for hepatocellular carcinoma
Journal Articles

Abstract 4815: Differential expression profiling of long noncoding RNA establishes UCA1 as a hallmark of renal medullary carcinoma

Pavlos Msaouel, Gabriel G. Malouf, Xiaoping Su, Hui Yao, Durga N. Tripathi, Jianjun Gao, Priya Rao, Jean-Philippe Bertocchio, Jose Karam, Christopher G. Wood, Cheryl L. Walker, Giannicola Genovese, Nizar M. Tannir
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4815.
https://doi.org/10.1158/1538-7445.AM2020-4815
Published: 15 August 2020
View articletitled, Abstract 4815: Differential expression profiling of long noncoding RNA establishes UCA1 as a hallmark of renal medullary carcinoma
Journal Articles

Abstract 3054: Targeting TGF-β signaling for obesity/insulin resistance-associated hepatocellular carcinoma

Jian Chen, Xiaoping Su, Andres Rojas, Robert S Bresalier, John R. Stroehlein, Sai-ching Yeung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3054.
https://doi.org/10.1158/1538-7445.AM2020-3054
Published: 15 August 2020
View articletitled, Abstract 3054: Targeting TGF-β signaling for obesity/insulin resistance-associated hepatocellular carcinoma
Journal Articles

Abstract 4143: Identification of molecular targets for conservative management of early stage, low-grade endometrial cancer through compartment-specific transcriptome profiling

Qian Zhang, Xiaoping Su, Joseph Celestino, Ying Yuan, Samuel C. Mok, Karen H. Lu, Melinda S. Yates
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4143.
https://doi.org/10.1158/1538-7445.AM2020-4143
Published: 15 August 2020
View articletitled, Abstract 4143: Identification of molecular targets for conservative management of early stage, low-grade endometrial cancer through compartment-specific transcriptome profiling
Journal Articles

Abstract A20: Single-cell immune TCR repertoire profiling in the context of immunotherapy by using three 10x Genomics libraries

Yuan Qi, Jin Seon Im, Xiaoping Su
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A20.
https://doi.org/10.1158/1538-7445.PEDCA19-A20
Published: 15 July 2020
View articletitled, Abstract A20: Single-cell immune TCR repertoire profiling in the context of immunotherapy by using three 10x Genomics libraries
Journal Articles

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling

Jian Chen, Abhisek Mitra, Shulin Li, Shumei Song, Bao-Ngoc Nguyen, Jiun-Sheng Chen, Ji-Hyun Shin, Nancy R. Gough, Paul Lin, Vincent Obias, Aiwu Ruth He, Zhixing Yao, Tathiane M. Malta, Houtan Noushmehr, Patricia S. Latham, Xiaoping Su, Asif Rashid, Bibhuti Mishra, Ray-Chang Wu, Lopa Mishra
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (9): 1819–1832.
https://doi.org/10.1158/0008-5472.CAN-19-3116
Published: 04 May 2020
View articletitled, Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling
Open the PDF for Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 1105: Tumor cells of the early metastatic process show up regulation of cytokine genes involved in migration of inflammatory cells

Coya Tapia, Xiaoping Su, Ximing Tang, Lakshmi Kakaral, Aysegul Sahin, Wei Lu, Ignacio I. Wistuba
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1105.
https://doi.org/10.1158/1538-7445.AM2018-1105
Published: 01 July 2018
View articletitled, Abstract 1105: Tumor cells of the early metastatic process show up regulation of cytokine genes involved in migration of inflammatory cells
Journal Articles

NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas

Xiaoping Su, Jianping Zhang, Roger Mouawad, Eva Compérat, Morgan Rouprêt, Frederick Allanic, Jérôme Parra, Marc-Olivier Bitker, Erika J. Thompson, Banumathy Gowrishankar, Jane Houldsworth, John N. Weinstein, Jorg Tost, Bradley M. Broom, David Khayat, Jean-Philippe Spano, Nizar M. Tannir, Gabriel G. Malouf
Journal: Cancer Research
Cancer Res (2017) 77 (18): 4835–4845.
https://doi.org/10.1158/0008-5472.CAN-17-0143
Published: 14 September 2017
View articletitled, NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas
Open the PDF for NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas in another window
Includes: Supplementary data
Journal Articles

Abstract 4970: Oxidative phosphorylation as a target in triple negative breast cancer therapy

Funda Meric-Bernstam, Kurt Evans, Xiaofeng Zheng, Xiaoping Su, Erkan Yuca, Stephen Scott, Argun Akcakanat, Naoto Ueno, Bora Lim, Jennifer Litton, Vicente Valero, Fraser Symmans, Gabriel Hortobagyi, Charles Perou, Debu Tripathy, Guilio Draetta, Joe Marszalek, Ana Maria Gonzalez-Angulo, Stacy Moulder
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4970.
https://doi.org/10.1158/1538-7445.AM2017-4970
Published: 01 July 2017
View articletitled, Abstract 4970: Oxidative phosphorylation as a target in triple negative breast cancer therapy
Journal Articles

Abstract 5405: Comprehensive analysis of long non-coding RNAs in human stomach adenocarcinoma molecular subtypes

Jian Chen, Jiun-Sheng Chen, Keping Xie, John R Stroehlein, Marta Davila, Xiaoping Su
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5405.
https://doi.org/10.1158/1538-7445.AM2017-5405
Published: 01 July 2017
View articletitled, Abstract 5405: Comprehensive analysis of long non-coding RNAs in human stomach adenocarcinoma molecular subtypes
Journal Articles

Abstract 3594: The TGF-β effector β2SP depletion abrogates DNA damage repair

Jian Chen, Vivek Shukla, Jiun-Sheng Chen, Raj K. Panditab, Yun Seong Jeong, Lior H Katz, Ji-Hyun Shin, YoungJin Gi, Lawrence N. Kwongc, Clayton R. Huntb, Patrizia Farci, Xiaoping Su, Jon White, Bibhuti Mishra, Asif Rashid, Milind Javle, Lei Li, Junjie Chen, John R Stroehlein, Marta Davila, Rehan Akbani, Keigo Machidao, Hidekazu Tsukamoto, Tej K. Pandita, Lopa Mishra
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3594.
https://doi.org/10.1158/1538-7445.AM2016-3594
Published: 15 July 2016
View articletitled, Abstract 3594: The TGF-β effector β2SP depletion abrogates DNA damage repair