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Journal Articles

Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci

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Bin Li, Yimin Cai, Can Chen, Gaoyuan Li, Ming Zhang, Zequn Lu, Fuwei Zhang, Jinyu Huang, Linyun Fan, Caibo Ning, Yanmin Li, Wenzhuo Wang, Hui Geng, Yizhuo Liu, Shuoni Chen, Hanting Li, Shuhui Yang, Heng Zhang, Wen Tian, Zhongchao Zhu, Bin Xu, Heng Li, Haijie Li, Meng Jin, Xiaoyang Wang, Shaokai Zhang, Jiuyang Liu, Chaoqun Huang, Xiaojun Yang, Yongchang Wei, Ying Zhu, Jianbo Tian, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2023) 83 (21): 3650–3666.
https://doi.org/10.1158/0008-5472.CAN-23-0251
Published: 01 November 2023
View articletitled, Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci
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Includes: Supplementary data
Journal Articles

Pan-Cancer Analysis of Microbiome Quantitative Trait Loci

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Can Chen, Yimin Cai, Yizhuo Liu, Shuoni Chen, Yanmin Li, Fuwei Zhang, Ming Zhang, Zequn Lu, Pingting Ying, Jinyu Huang, Linyun Fan, Xiaomin Cai, Caibo Ning, Wenzhuo Wang, Yuan Jiang, Heng Zhang, Shuhui Yang, Zhihua Wang, Xiaoyang Wang, Shaokai Zhang, Chaoqun Huang, Bin Xu, Zhenming Fu, Qibin Song, Mingjuan Jin, Kun Chen, Hongda Chen, Min Dai, Xiaoping Miao, Xiaojun Yang, Ying Zhu, Jianbo Tian
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3449–3456.
https://doi.org/10.1158/0008-5472.CAN-22-1854
Published: 04 October 2022
View articletitled, Pan-Cancer Analysis of Microbiome Quantitative Trait Loci
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Includes: Supplementary data
Journal Articles

Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk

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Jianbo Tian, Can Chen, Meilin Rao, Ming Zhang, Zequn Lu, Yimin Cai, Pingting Ying, Bin Li, Haoxue Wang, Lu Wang, Yao Li, Jinyu Huang, Linyun Fan, Xiaomin Cai, Caibo Ning, Yanmin Li, Fuwei Zhang, Wenzhuo Wang, Yuan Jiang, Yizhuo Liu, Min Wang, Heng Li, Chaoqun Huang, Zhiyong Yang, Jiang Chang, Ying Zhu, Xiaojun Yang, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2022) 82 (11): 2084–2096.
https://doi.org/10.1158/0008-5472.CAN-21-4367
Published: 06 June 2022
View articletitled, Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk
Open the PDF for Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk in another window
Includes: Supplementary data
Journal Articles

Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both FADS2 and AP002754.2

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Jianbo Tian, Jiao Lou, Yimin Cai, Meilin Rao, Zequn Lu, Ying Zhu, Danyi Zou, Xiating Peng, Haoxue Wang, Ming Zhang, Siyuan Niu, Yue Li, Rong Zhong, Jiang Chang, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2020) 80 (9): 1804–1818.
https://doi.org/10.1158/0008-5472.CAN-19-2389
Published: 04 May 2020
View articletitled, Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both FADS2 and AP002754.2
Open the PDF for Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both FADS2 and AP002754.2 in another window
Includes: Supplementary data
Journal Articles

A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer

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Jiang Chang, Jianbo Tian, Yang Yang, Rong Zhong, Jiaoyuan Li, Kan Zhai, Juntao Ke, Jiao Lou, Wei Chen, Beibei Zhu, Na Shen, Yi Zhang, Yajie Gong, Ying Zhu, Danyi Zou, Xiating Peng, Kun Huang, Xiaoping Miao
Journal: Cancer Research
Cancer Res (2018) 78 (17): 5164–5172.
https://doi.org/10.1158/0008-5472.CAN-18-0910
Published: 04 September 2018
View articletitled, A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer
Open the PDF for A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer in another window
Includes: Supplementary data
Journal Articles

Variations in HSPA1B at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations

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Huan Guo, Qifei Deng, Chen Wu, Lingmin Hu, Sheng Wei, Ping Xu, Dan Kuang, Li Liu, Zhibin Hu, Xiaoping Miao, Hongbing Shen, Dongxin Lin, Tangchun Wu
Journal: Cancer Research
Cancer Res (2011) 71 (24): 7576–7586.
https://doi.org/10.1158/0008-5472.CAN-11-1409
Published: 15 December 2011
View articletitled, Variations in HSPA1B at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations
Open the PDF for Variations in HSPA1B at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations in another window
Includes: Supplementary data
Journal Articles

Genome-Wide Interrogation Identifies YAP1 Variants Associated with Survival of Small-Cell Lung Cancer Patients

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Chen Wu, Binghe Xu, Peng Yuan, Xiaoping Miao, Yu Liu, Yin Guan, Dianke Yu, Jian Xu, Tongwen Zhang, Hongbing Shen, Tangchun Wu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2010) 70 (23): 9721–9729.
https://doi.org/10.1158/0008-5472.CAN-10-1493
Published: 06 December 2010
View articletitled, Genome-Wide Interrogation Identifies YAP1 Variants Associated with Survival of Small-Cell Lung Cancer Patients
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Includes: Supplementary data
Journal Articles

The Role of P53 and MDM2 Polymorphisms in the Risk of Esophageal Squamous Cell Carcinoma

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Yuan Hong, Xiaoping Miao, Xuemei Zhang, Fang Ding, Aiping Luo, Yongli Guo, Wen Tan, Zhihua Liu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2005) 65 (20): 9582–9587.
https://doi.org/10.1158/0008-5472.CAN-05-1460
Published: 17 October 2005
View articletitled, The Role of P53 and MDM2 Polymorphisms in the Risk of Esophageal Squamous Cell Carcinoma
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Journal Articles

Polymorphisms in DNA Base Excision Repair Genes ADPRT and XRCC1 and Risk of Lung Cancer

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Xuemei Zhang, Xiaoping Miao, Gang Liang, Bingtao Hao, Yonggang Wang, Wen Tan, Yi Li, Yongli Guo, Fuchu He, Qingyi Wei, Dongxin Lin
Journal: Cancer Research
Cancer Res (2005) 65 (3): 722–726.
https://doi.org/10.1158/0008-5472.722.65.3
Published: 10 February 2005
View articletitled, Polymorphisms in DNA Base Excision Repair Genes ADPRT and XRCC1 and Risk of Lung Cancer
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Journal Articles

Functional Haplotypes in the Promoter of Matrix Metalloproteinase-2 Predict Risk of the Occurrence and Metastasis of Esophageal Cancer

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Chunyuan Yu, Yifeng Zhou, Xiaoping Miao, Ping Xiong, Wen Tan, Dongxin Lin
Journal: Cancer Research
Cancer Res (2004) 64 (20): 7622–7628.
https://doi.org/10.1158/0008-5472.CAN-04-1521
Published: 15 October 2004
View articletitled, Functional Haplotypes in the Promoter of Matrix Metalloproteinase-2 Predict Risk of the Occurrence and Metastasis of Esophageal Cancer
Open the PDF for Functional Haplotypes in the Promoter of Matrix Metalloproteinase-2 Predict Risk of the Occurrence and Metastasis of Esophageal Cancer in another window
Journal Articles

Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

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Bingtao Hao, Haijian Wang, Kaixin Zhou, Yi Li, Xiaoping Chen, Gangqiao Zhou, Yunping Zhu, Xiaoping Miao, Wen Tan, Qingyi Wei, Dongxin Lin, Fuchu He
Journal: Cancer Research
Cancer Res (2004) 64 (12): 4378–4384.
https://doi.org/10.1158/0008-5472.CAN-04-0372
Published: 17 June 2004
View articletitled, Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Functional STK15 Phe31Ile Polymorphism Is Associated with the Occurrence and Advanced Disease Status of Esophageal Squamous Cell Carcinoma

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Xiaoping Miao, Tong Sun, Yonggang Wang, Xuemei Zhang, Wen Tan, Dongxin Lin
Journal: Cancer Research
Cancer Res (2004) 64 (8): 2680–2683.
https://doi.org/10.1158/0008-5472.CAN-04-0651
Published: 15 April 2004
View articletitled, Functional STK15 Phe31Ile Polymorphism Is Associated with the Occurrence and Advanced Disease Status of Esophageal Squamous Cell Carcinoma
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Journal Articles

Functional polymorphisms in the Fas and FasL gene promoters and risk of development and progression of esophageal squamous cell carcinoma

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Tong Sun, Xiaoping Miao, Xuemei Zhang, Wen Tan, Ping Xiong, Dong-Xin Lin
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1045.
Published: 01 April 2004
View articletitled, Functional polymorphisms in the Fas and FasL gene promoters and risk of development and progression of esophageal squamous cell carcinoma
Journal Articles

Substantial Reduction in Risk of Lung Adenocarcinoma Associated with Genetic Polymorphism in CYP2A13, the Most Active Cytochrome P450 for the Metabolic Activation of Tobacco-Specific Carcinogen NNK

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Haijian Wang, Wen Tan, Bingtao Hao, Xiaoping Miao, Gangqiao Zhou, Fuchu He, Dongxin Lin
Journal: Cancer Research
Cancer Res (2003) 63 (22): 8057–8061.
Published: 21 November 2003
View articletitled, Substantial Reduction in Risk of Lung Adenocarcinoma Associated with Genetic Polymorphism in CYP2A13, the Most Active Cytochrome P450 for the Metabolic Activation of Tobacco-Specific Carcinogen NNK
Open the PDF for Substantial Reduction in Risk of Lung Adenocarcinoma Associated with Genetic Polymorphism in CYP2A13, the Most Active Cytochrome P450 for the Metabolic Activation of Tobacco-Specific Carcinogen NNK in another window
Journal Articles

A Functional Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter (−1306C/T) Is Associated with Risk of Development but not Metastasis of Gastric Cardia Adenocarcinoma

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Xiaoping Miao, Chunyuan Yu, Wen Tan, Ping Xiong, Gang Liang, Wenfu Lu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2003) 63 (14): 3987–3990.
Published: 21 July 2003
View articletitled, A Functional Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter (−1306C/T) Is Associated with Risk of Development but not Metastasis of Gastric Cardia Adenocarcinoma
Open the PDF for A Functional Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter (−1306C/T) Is Associated with Risk of Development but not Metastasis of Gastric Cardia Adenocarcinoma in another window