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Journal Articles

Abstract 2371: BGB-B167, a first-in-class 4-1BB/CEACAM5 bispecific antibody, exhibits potent in vitro and < for vivo antitumor activity and < for superior safety profile in preclinical models

Zhuo Li, Liang Qu, Xin Chen, Liu Xue, Jie Li, Qi Liu, Jian Sun, Hanzi Sun, Yun Chen, Yuanyuan Xie, Wanyi Wang, Lin Zhu, Penghao Wang, Xiaosui Zhou, Hongjia Hou, Jie Chen, Xinyi Liu, Yilu Zhang, Ning Liu, Xinyi Liang, Shuo Zhang, Xiaoyan Tang, Jing Song, Tong Zhang, Xiaomin Song, Xuesong Liu, Kang Li, Chichi Huang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2371.
https://doi.org/10.1158/1538-7445.AM2024-2371
Published: 22 March 2024
View article titled, Abstract 2371: BGB-B167, a first-in-class 4-1BB/CEACAM5 bispecific antibody, exhibits potent in vitro and &amp;lt; for vivo antitumor activity and &amp;lt; for superior safety profile in preclinical models
Journal Articles

Abstract 2110: Characterization of the correlation between BTK degradation and tumor growth inhibition of the BTK target protein degraders using PK/PD modeling

Yue Wu, Shuran Li, Fan Wang, Nan Hu, Longbo Yin, Xiaomin Song, Jiye Zhang, Aiying Xu, Shasha Yang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2110.
https://doi.org/10.1158/1538-7445.AM2024-2110
Published: 22 March 2024
View article titled, Abstract 2110: Characterization of the correlation between BTK degradation and tumor growth inhibition of the BTK target protein degraders using PK/PD modeling
Journal Articles

Abstract 6158: BGB-24714, a novel oral IAP antagonist, displayed significant anti-tumor activities in preclinical models as a monotherapy and in combination with paclitaxel

Jie Li, Nan Hu, Yilu Zhang, Xiaolong Yang, Minjuan Deng, Wenfeng Gong, Longbo Yin, Yong Liu, Yajuan Gao, Wei Wei, Xing Wang, Xinyi Liang, Yanwen Ma, Xuxing Sang, Chang Liu, Jingyuan Wang, Qianqian Lu, Fengtao Song, Xi Yuan, Yibing Wang, Jing Li, Wei Jin, Xuesong Liu, Xiaomin Song
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6158.
https://doi.org/10.1158/1538-7445.AM2023-6158
Published: 04 April 2023
View article titled, Abstract 6158: BGB-24714, a novel oral IAP antagonist, displayed significant anti-tumor activities in preclinical models as a monotherapy and in combination with paclitaxel
Journal Articles

Abstract 5541: BGB-15025, a potent and selective HPK1 inhibitor, is efficacious as a single agent or in combination with PD-1 antibody in multiple tumor models

Ye Liu, Jing Li, Zhuo Li, Qin Wang, Xing Zhou, Xiaoxin Liu, Bo Zhang, Xitao Wang, Sanjia Xu, Hanzi Sun, Xiaomin Song, Xi Yuan, Zhiwei Wang, Xuesong Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5541.
https://doi.org/10.1158/1538-7445.AM2022-5541
Published: 15 June 2022
View article titled, Abstract 5541: BGB-15025, a potent and selective HPK1 inhibitor, is efficacious as a single agent or in combination with PD-1 antibody in multiple tumor models
Journal Articles

Abstract 664: BGB-10188, a highly selective PI3Kδ inhibitor with improved safety profile and superior anti-tumor activities in vivo

Xiao Yang, Xiaolong Yang, Xinxin Cui, Dan Su, Yue Wu, Xuebing Sun, Jingyuan Wang, Huichen Bai, Wei Wei, Jing Li, Xi Yuan, Ye Liu, Fan Wang, Zhiwei Wang, Lai Wang, Xuesong Liu, Xiaomin Song
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 664.
https://doi.org/10.1158/1538-7445.AM2020-664
Published: 15 August 2020
View article titled, Abstract 664: BGB-10188, a highly selective PI3Kδ inhibitor with improved safety profile and superior anti-tumor activities in vivo
Journal Articles

Abstract 3077: Preclinical characterization of BGB-11417, a potent and selective Bcl-2 inhibitor with superior antitumor activities in haematological tumor models

Nan Hu, Yunhang Guo, Hai Xue, Ye Liu, Yin Guo, Fan Wang, Xiaomin Song, Ying Guo, Shuaishuai Chen, Haipeng Xu, Taichang Zhang, Yanwen Ma, Xuebing Sun, Yuan Hong, Yutong Zhu, Aiying Xu, Zhenzhen Cheng, Haimei Xing, Zhiwei Wang, Xuesong Liu, Lai Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3077.
https://doi.org/10.1158/1538-7445.AM2020-3077
Published: 15 August 2020
View article titled, Abstract 3077: Preclinical characterization of BGB-11417, a potent and selective Bcl-2 inhibitor with superior antitumor activities in haematological tumor models
Journal Articles

Abstract 2628: BGB-A425: a humanized anti-human Tim-3 antibody that exhibits strong immune cell activation

Tong Zhang, Liu Xue, Jing Zhang, Qi Liu, Jie Ma, Yi Zhang, Yingdi Shi, Hongjia Hou, Hao Peng, Ning Liu, Yilu Zhang, Xiaomin Song, Yucheng Li, Jing Song, Lai Wang, Min Wei, Kang Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2628.
https://doi.org/10.1158/1538-7445.AM2017-2628
Published: 01 July 2017
View article titled, Abstract 2628: BGB-A425: a humanized anti-human Tim-3 antibody that exhibits strong immune cell activation
Journal Articles

Abstract 2226: Anti-human PD-1 antibody BGB-A317 exhibits potent immune cell activation

Tong Zhang, Jing Song, Yucheng Li, Jie Ma, Yingdi Shi, Xiaoran Wu, Lanlan Xu, Qi Liu, Yanping Cao, Yali Wang, Hao Peng, Hongjia Hou, Xu Zhao, Xiaomin Song, Lai Wang, Min Wei, Lusong Luo, Kang Li
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2226.
https://doi.org/10.1158/1538-7445.AM2016-2226
Published: 15 July 2016
View article titled, Abstract 2226: Anti-human PD-1 antibody BGB-A317 exhibits potent immune cell activation
Journal Articles

Abstract 5002: Anti-tumor activity of a novel anti-human PD-1 antibody BGB-A317 in mouse models

Xiaomin Song, Zhiyu Tang, Tong Zhang, Mingming Guo, Wenfeng Gong, Yong Liu, Ningning Zhang, Yilu Zhang, Yanjuan Zhang, Jie Ma, Jing Song, Kang Li, Lai Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5002.
https://doi.org/10.1158/1538-7445.AM2016-5002
Published: 15 July 2016
View article titled, Abstract 5002: Anti-tumor activity of a novel anti-human PD-1 antibody BGB-A317 in mouse models
Journal Articles

Overexpression of Platelet-Derived Growth Factor-BB Increases Tumor Pericyte Content via Stromal-Derived Factor-1α/CXCR4 Axis

Nan Song, Yujie Huang, Hubing Shi, Shaopeng Yuan, Yanping Ding, Xiaomin Song, Yan Fu, Yongzhang Luo
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6057–6064.
https://doi.org/10.1158/0008-5472.CAN-08-2007
Published: 29 July 2009
View article titled, Overexpression of Platelet-Derived Growth Factor-BB Increases Tumor Pericyte Content via Stromal-Derived Factor-1α/CXCR4 Axis
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