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Abstract 1595: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry

Amanda L. Rinkenbaugh, Vidya C. Sinha, Pankaj Singh, Yuan Qi, Jiansu Shao, Xiaomei Zhang, Gloria V. Echeverria, W. Fraser Symmans, Stacy L. Moulder, Helen Piwnica-Worms

Cancer Res (2022) 82 (12_Supplement): 1595.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1595

Published: 15 June 2022

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Journal Articles

Abstract PR01: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry

Amanda L. Rinkenbaugh, Vidya C. Sinha, Jiansu Shao, Xiaomei Zhang, Gloria V. Echeverria, W. Fraser Symmans, Stacy L. Moulder, Helen Piwnica-Worms

Cancer Res (2020) 80 (21_Supplement): PR01.

DOI: https://doi.org/10.1158/1538-7445.TUMHET2020-PR01

Published: 03 November 2020

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Journal Articles

Abstract 1513: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry

Amanda L. Rinkenbaugh, Vidya C. Sinha, Gloria V. Echeverria, Xiaomei Zhang, Jiansu Shao, W. Fraser Symmans, Stacy L. Moulder, Helen Piwnica-Worms

Cancer Res (2020) 80 (16_Supplement): 1513.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1513

Published: 15 August 2020

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Journal Articles

Abstract 2822: Single-cell evaluation to identify tumor-stroma niches driving the transition from in situ to invasive breast cancer

Vidya C. Sinha, Mingchu Xu, Amanda L. Rinkenbaugh, Xinhui Zhou, Xiaomei Zhang, Helen Piwnica-Worms

Cancer Res (2020) 80 (16_Supplement): 2822.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2822

Published: 15 August 2020

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Journal Articles

Abstract GS4-02: Investigating genomic and phenotypic evolution of triple negative breast cancer chemoresistance and metastasis in patient-derived xenografts

Gloria V Echeverria, Mingchu Xu, Jiansu Shao, Xiaomei Zhang, Sabrina Jeter-Jones, Xinhui Zhou, Stacy L Moulder, Joseph R Marszalek, Timothy P Heffernan, Fraser W Symmans, Jeffrey T Chang, Helen Piwnica-Worms

Cancer Res (2020) 80 (4_Supplement): GS4-02.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-GS4-02

Published: 15 February 2020

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Journal Articles

Abstract 2901: Clonal dynamics and phenotypic evolution during chemoresistance and metastasis revealed by patient-derived xenograft models of triple negative breast cancer

Cancer Res (2019) 79 (13_Supplement): 2901.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2901

Published: 01 July 2019

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Journal Articles

Abstract 4708: Investigating triple negative breast cancer phenotypic heterogeneity of human and patient-derived xenograft samples using imaging mass cytometry

Amanda L. Rinkenbaugh, Vidya C. Sinha, Xiaomei Zhang, Jiansu Shao, Helen Piwnica-Worms

Cancer Res (2019) 79 (13_Supplement): 4708.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4708

Published: 01 July 2019

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Journal Articles

Abstract 212: High-resolution barcoding in patient-derived xenografts of triple-negative breast cancer reveals reversible chemoresistance conferred by non-mutational mechanisms

Cancer Res (2018) 78 (13_Supplement): 212.

DOI: https://doi.org/10.1158/1538-7445.AM2018-212

Published: 01 July 2018

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Journal Articles

Abstract 2181: Functionalizing intratumoral signaling heterogeneity in triple negative breast cancer

Amanda L. Rinkenbaugh, Vidya C. Sinha, Xiaomei Zhang, Helen Piwnica-Worms

Cancer Res (2018) 78 (13_Supplement): 2181.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2181

Published: 01 July 2018

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Journal Articles

Abstract 2139: Wild type N-Ras, overexpressed in basal-like breast cancer, promotes tumor formation by inducing IL8 secretion via JAK2 activation

Ze-Yi Zheng, Wen Bu, Lin Tian, Cheng Fan, Xia Gao, Cuijuan Yu, Liu Jun, Xiaomei Zhang, Yi-Hua Liao, Yi Li, Michael T. Lewis, Dean Edwards, Susan G. Hilsenbeck, Daniel Medina, Thomas P. Zwaka, Charles M. Perou, Chad J. Creighton, Xiang Zhang, Eric C. Chang

Cancer Res (2015) 75 (15_Supplement): 2139.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2139

Published: 01 August 2015

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Journal Articles

Abstract P4-01-06: Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

Cancer Res (2015) 75 (9_Supplement): P4-01-06.

DOI: https://doi.org/10.1158/1538-7445.SABCS14-P4-01-06

Published: 01 May 2015

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Journal Articles

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

Cancer Res (2013) 73 (15): 4885–4897.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-4081

Published: 31 July 2013

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Includes: Supplementary data

Journal Articles

Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow–Derived Monocytes

Vandana Iyer, Ina Klebba, Jessica McCready, Lisa M. Arendt, Monica Betancur-Boissel, Meng-Fen Wu, Xiaomei Zhang, Michael T. Lewis, Charlotte Kuperwasser

Cancer Res (2012) 72 (11): 2705–2713.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-3287

Published: 31 May 2012

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Includes: Supplementary data

Journal Articles

Abstract LB-305: Circulating tumor cells as a novel model to test efficacy of individualized therapy in breast cancer

mario giuliano, Meghana V. Trivedi, Pavel Christiny, Xiaomei Zhang, Sufeng Mao, Sabrina Herrera, Alejandro Contreras, Gary C. Chamness, Michael T. Lewis, Mothaffar F. Rimawi, Osborne K. Charles, Rachel Schiff

Cancer Res (2012) 72 (8_Supplement): LB-305.

DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-305

Published: 15 April 2012

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Journal Articles

Abstract #3223: Efficient generation of primary xenografts using normal and malignant human mammary epithelium in SCID/Beige mice without humanizing fibroblasts

Xiaomei Zhang, Jian Huang, Qing Lai, Xiaoxian Li, Ricardo Moraes, Helen Wong, Lisa Wiechmann, Rachel Schiff, Massimo Cristofanilli, Savitri Krishnamurthy, James Reuben, Wendy Woodward, Jenny Chang, Michael Lewis

Cancer Res (2009) 69 (9_Supplement): 3223.

Published: 01 May 2009

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Journal Articles

Abstract #1061: Selectively Targeting Breast Cancer Stem Cells

Melissa Landis, Xiaomei Zhang, Micheal Lewis, Jenny Chang

Cancer Res (2009) 69 (9_Supplement): 1061.

Published: 01 May 2009

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Journal Articles

Sorafenib Blocks the RAF/MEK/ERK Pathway, Inhibits Tumor Angiogenesis, and Induces Tumor Cell Apoptosis in Hepatocellular Carcinoma Model PLC/PRF/5

Li Liu, Yichen Cao, Charles Chen, Xiaomei Zhang, Angela McNabola, Dean Wilkie, Scott Wilhelm, Mark Lynch, Christopher Carter

Cancer Res (2006) 66 (24): 11851–11858.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-1377

Published: 18 December 2006

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Journal Articles

Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations

Xiaomei Zhang, Katrina Podsypanina, Shixia Huang, Syed K. Mohsin, Gary C. Chamness, Sarah Hatsell, Pam Cowin, Rachel Schiff, Yi Li

Cancer Res (2005) 65 (9_Supplement): 1240.

Published: 01 May 2005

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Journal Articles

BAY 43-9006 (Sorafenib) is a potent inhibitor of FLT3 tyrosine kinase signaling and proliferation in AML cells

Cancer Res (2005) 65 (9_Supplement): 1409.

Published: 01 May 2005

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Journal Articles

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

Cancer Res (2004) 64 (19): 7099–7109.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-1443

Published: 01 October 2004

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NARROW

Abstract 1595: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry

Abstract PR01: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry

Abstract 1513: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry

Abstract 2822: Single-cell evaluation to identify tumor-stroma niches driving the transition from in situ to invasive breast cancer

Abstract GS4-02: Investigating genomic and phenotypic evolution of triple negative breast cancer chemoresistance and metastasis in patient-derived xenografts

Abstract 2901: Clonal dynamics and phenotypic evolution during chemoresistance and metastasis revealed by patient-derived xenograft models of triple negative breast cancer

Abstract 4708: Investigating triple negative breast cancer phenotypic heterogeneity of human and patient-derived xenograft samples using imaging mass cytometry

Abstract 212: High-resolution barcoding in patient-derived xenografts of triple-negative breast cancer reveals reversible chemoresistance conferred by non-mutational mechanisms

Abstract 2181: Functionalizing intratumoral signaling heterogeneity in triple negative breast cancer

Abstract 2139: Wild type N-Ras, overexpressed in basal-like breast cancer, promotes tumor formation by inducing IL8 secretion via JAK2 activation

Abstract P4-01-06: Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow–Derived Monocytes

Abstract LB-305: Circulating tumor cells as a novel model to test efficacy of individualized therapy in breast cancer

Abstract #3223: Efficient generation of primary xenografts using normal and malignant human mammary epithelium in SCID/Beige mice without humanizing fibroblasts

Abstract #1061: Selectively Targeting Breast Cancer Stem Cells

Sorafenib Blocks the RAF/MEK/ERK Pathway, Inhibits Tumor Angiogenesis, and Induces Tumor Cell Apoptosis in Hepatocellular Carcinoma Model PLC/PRF/5

Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations

BAY 43-9006 (Sorafenib) is a potent inhibitor of FLT3 tyrosine kinase signaling and proliferation in AML cells

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

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