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Journal Articles

Abstract 7191: Targeted genomic and epigenomic dual analysis of the same region for an entire single gene

Free
Grace Q. Zhao, Heng Wang, Alexandra Harris, Yingmin Wang, Yingzhen Wang, Ling Su, Ashraf Wahba, Josh Wang, Yun Bao, Carole Durand, Bram Herman, Tiffany Dorsey, Shengrong Lin, Xiaolin Wu, Stefan Ambs
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7191.
https://doi.org/10.1158/1538-7445.AM2025-7191
Published: 21 April 2025
View article titled, Abstract 7191: Targeted genomic and epigenomic dual analysis of the same region for an entire single gene
Journal Articles

Abstract A006: Reckless mitotic entry as a novel chemosensitization approach for alkylating agents

Free
Fengchao Lang, James Cornwell, Karambir Kaur, Omar Elmogazy, Wei Zhang, Meili Zhang, Hua Song, Zhonghe Sun, Xiaolin Wu, Mirit I. Aladjem, Michael Aregger, Steven Cappell, Chunzhang Yang
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_1): A006.
https://doi.org/10.1158/1538-7445.BRAIN23-A006
Published: 04 March 2024
View article titled, Abstract A006: Reckless mitotic entry as a novel chemosensitization approach for alkylating agents
Journal Articles

Abstract C106: IMPACT restrains immuno-metabolic GCN1 signaling to govern pancreatic cancer metastasis

Free
Surajit Sinha, Abir Panda, Zeribe Nwosu, Rodrigo Neves Das, Xu Ke, Elke van Beek, Alexander J. Rossi, Reed I. Ayabe, James McDonald, Michael M. Wach, Samantha Ruff, Priyanka P. Desai, David Sun, Martha E. Teke, Emily A. Verbus, Areeba Saif, Shreya Gupta, Tahsin Khan, Leila Sarvestani, Carrie E. Ryan, Jacob Lambdin, Kirsten Remmert, Emily Smith, Kenneth Luberice, Stephie Lux, Imani A. Alexander, Tracey Pu, Allen Luna, Sarfraz R. Akmal, Shahyan Rehman, Ashley Rainey, Hanna Hong, Yuri Lin, Samantha Sevilla, Gasmi Billel, Sivasish Sindiri, Todd Prickett, King Chan, Eileen Li, Xiaolin Wu, Nicholas D. Klemen, Giorgio Trinchieri, Costas A. Lyssiotis, Jeremy Davis, Pankaj K. Singh, Steven A. Rosenberg, Michael B. Yaffe, Filippo Giancotti, Ethan M. Shevach, Jonathan M. Hernandez
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): C106.
https://doi.org/10.1158/1538-7445.PANCA2023-C106
Published: 16 January 2024
View article titled, Abstract C106: IMPACT restrains immuno-metabolic GCN1 signaling to govern pancreatic cancer metastasis
Journal Articles

Abstract 926: IIKKa deletion amplifies renal transitional epithelial stem cells and initiates lethal invasive papillary urothelial cell carcinoma development

Free
Xin Li, Feng Zhu, Chengfei Jiang, Yongmei Zhao, Bao Tran, Donna Butcher, Xiaolin Wu, Tross Debra, Yinling Hu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 926.
https://doi.org/10.1158/1538-7445.AM2022-926
Published: 15 June 2022
View article titled, Abstract 926: IIKKa deletion amplifies renal transitional epithelial stem cells and initiates lethal invasive papillary urothelial cell carcinoma development
Journal Articles

Abstract 2658: Oncogenicity of adeno-associated virus (AAV) integration into the genomes of liver cancer patients depends on the overlap between the AAV integration site and the AAV X gene

Free
Alejandro A. Schaffer, Dana Dominguez, E. M. Gertz, Lesley M. Chapman, Anuradha Budhu, Marshonna Forgues, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Xiaolin Wu, Curtis C. Harris, Mathuros Ruchirawat, Eytan Ruppin, Xin W. Wang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2658.
https://doi.org/10.1158/1538-7445.AM2021-2658
Published: 01 July 2021
View article titled, Abstract 2658: Oncogenicity of adeno-associated virus (AAV) integration into the genomes of liver cancer patients depends on the overlap between the AAV integration site and the AAV X gene
Journal Articles

Abstract 4611: A multicenter clinical study of stool DNA test of methylated syndecan-2 for colorectal cancer detection

Free
Jianping Wang, Side Liu, Hui Wang, Lei Zheng, Changchun Zhou, Guoxin Li, Rongkang Huang, Huaiming Wang, Chujun Li, Xinjuan Fan, Xinhui Fu, Xinying Wang, Hongliang Guo, Jie Guan, Yanlai Sun, Xilin Song, Zengjun Li, Dianbin Mu, Jujie Sun, Xianglin Liu, Yan Qi, Feng Niu, Chunhua Chen, Xiaolin Wu, Xianshu Wang, Xianrang Song, Hongzhi Zou
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4611.
https://doi.org/10.1158/1538-7445.AM2020-4611
Published: 15 August 2020
View article titled, Abstract 4611: A multicenter clinical study of stool DNA test of methylated syndecan-2 for colorectal cancer detection
Journal Articles

Abstract B17: IKKα/STAT3 antagonistic signaling regulates fungi-bacteria endosymbiosis-associated carcinogenesis

Free
Na-Young Song, Xin Li, Jonathan H. Badger, Jami Willette Brown, Xhonghe Sun, Gongping Shi, Feng Zhu, Chengfei Jiang, Colum O'hUigin, Xiaolin Wu, Giorgio Trinchieri, Yinling Hu
Journal: Cancer Research
Cancer Res (2020) 80 (8_Supplement): B17.
https://doi.org/10.1158/1538-7445.MVC2020-B17
Published: 15 April 2020
View article titled, Abstract B17: IKKα/STAT3 antagonistic signaling regulates fungi-bacteria endosymbiosis-associated carcinogenesis
Journal Articles

Radiation Drives the Evolution of Orthotopic Xenografts Initiated from Glioblastoma Stem–like Cells

Free
Joseph H. McAbee, Barbara H. Rath, Kristin Valdez, Dejauwne L. Young, Xiaolin Wu, Uma T. Shankavaram, Kevin Camphausen, Philip J. Tofilon
Journal: Cancer Research
Cancer Res (2019) 79 (23): 6032–6043.
https://doi.org/10.1158/0008-5472.CAN-19-2452
Published: 02 December 2019
View article titled, Radiation Drives the Evolution of Orthotopic Xenografts Initiated from Glioblastoma Stem–like Cells
Open the PDF for Radiation Drives the Evolution of Orthotopic Xenografts Initiated from Glioblastoma Stem–like Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 2355: IKKa serves as a molecular switch linking miRNA biogenesis and inflammation in skin tumorigenesis

Free
Feng Zhu, Jian Zhang, Jami Willette-Brown, Ling Su, Xiaolin Wu, Yinling Hu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2355.
https://doi.org/10.1158/1538-7445.AM2019-2355
Published: 01 July 2019
View article titled, Abstract 2355: IKKa serves as a molecular switch linking miRNA biogenesis and inflammation in skin tumorigenesis
Journal Articles

Abstract 2311: Analysis of glypican 3-targeted chimeric antigen receptor T cells in hepatocellular carcinoma cell and mouse models

Free
Dan Li, Nan Li, Yifan Zhang, Haiying Fu, Zhijian Duan, Alissa Hummer, Hongjia Yang, Madeline B. Torres, Xiaoling Luo, Ling Su, Hu Zhu, Josh Kramer, Jinqiu Chen, Xiaolin Wu, Matthew Hall, Qun Wang, Stephen Hewitt, Tim Greten, Mitchell Ho
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2311.
https://doi.org/10.1158/1538-7445.AM2019-2311
Published: 01 July 2019
View article titled, Abstract 2311: Analysis of glypican 3-targeted chimeric antigen receptor T cells in hepatocellular carcinoma cell and mouse models
Journal Articles

Abstract 3727: An orthotopic xenograft model for studying reirradiation and glioblastoma evolution

Free
Joseph H. McAbee, Barbara H. Rath, Xiaolin Wu, Uma Shankavaram, Kevin Camphausen, Philip J. Tofilon
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3727.
https://doi.org/10.1158/1538-7445.AM2019-3727
Published: 01 July 2019
View article titled, Abstract 3727: An orthotopic xenograft model for studying reirradiation and glioblastoma evolution
Journal Articles

Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Free
Atsushi Takai, Hien Dang, Naoki Oishi, Subreen Khatib, Sean P. Martin, Dana A. Dominguez, Ji Luo, Rachel Bagni, Xiaolin Wu, Katie Powell, Qing-Hai Ye, Hu-Liang Jia, Lun-Xiu Qin, Jinqiu Chen, Gary A. Mitchell, Xiaoling Luo, Snorri S. Thorgeirsson, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2379–2391.
https://doi.org/10.1158/0008-5472.CAN-18-3015
Published: 01 May 2019
View article titled, Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma
Open the PDF for Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel

Free
Anne Monks, Yingdong Zhao, Curtis Hose, Hossein Hamed, Julia Krushkal, Jianwen Fang, Dmitriy Sonkin, Alida Palmisano, Eric C. Polley, Laura K. Fogli, Mariam M. Konaté, Sarah B. Miller, Melanie A. Simpson, Andrea Regier Voth, Ming-Chung Li, Erik Harris, Xiaolin Wu, John W. Connelly, Annamaria Rapisarda, Beverly A. Teicher, Richard Simon, James H. Doroshow
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (24): 6807–6817.
https://doi.org/10.1158/0008-5472.CAN-18-0989
Published: 13 December 2018
View article titled, The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel
Open the PDF for The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel in another window
Includes: Supplementary data
Journal Articles

Abstract 4390: The Thailand initiative in genomics and expression research in liver cancer: Race related common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma identified by integrated genomics

Free
Anuradha Budhu, Jittiporn Chaisaingmongkol, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, So Mee Kwon, Marshonna Forgues, Yotsawat Pomyen, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu U. Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Maggie Cam, Ping He, Stephen M. Hewitt, Xiaolin Wu, Snorri S. Thorgeirsson, Joshua J. Waterfall, Yuelin J. Zhu, Jennifer Walling, Holly S. Stevenson, Daniel Edelman, Paul S. Meltzer, Christopher A. Loffredo, Robert H. Wiltrout, Curtis C. Harris, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin W. Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4390.
https://doi.org/10.1158/1538-7445.AM2017-4390
Published: 01 July 2017
View article titled, Abstract 4390: The Thailand initiative in genomics and expression research in liver cancer: Race related common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma identified by integrated genomics
Journal Articles

Abstract 4330: Astrocytic S1P3 regulates blood-brain/tumor barrier permeability

Free
Anurag N. Paranjape, Brunilde Gril, Stephan Woditschka, Emily Hua, Jeffrey C. Hanson, Xiaolin Wu, Renata Duchnowska, Priscilla K. Brastianos, David L. Liewehr, Seth M. Steinberg, Cody Peer, William D. Figg, Gary T. Pauly, Christina Robinson, Joel P. Schneider, Patricia S. Steeg
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4330.
https://doi.org/10.1158/1538-7445.AM2017-4330
Published: 01 July 2017
View article titled, Abstract 4330: Astrocytic S1P3 regulates blood-brain/tumor barrier permeability
Journal Articles

Abstract 1131: Uncovering oncogenic KRAS allele specific phenotypes using an isogenic MEF cell line system

Free
Nicole Fer, Brian Smith, Leslie Garvey, William Burgan, Katie Powell, Kanika Sharma, Andrew Waters, Xiaolin Wu, Dan Soppet, Robert Stephens, Dwight Nissley, Matthew Holderfield, Rachel K. Bagni
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1131.
https://doi.org/10.1158/1538-7445.AM2016-1131
Published: 15 July 2016
View article titled, Abstract 1131: Uncovering oncogenic KRAS allele specific phenotypes using an isogenic MEF cell line system
Journal Articles

Abstract LB-173: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma

Free
Jittiporn Chaisaingmongkol, Anuradha Budhu, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, Marshonna Forgues, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu U. Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Maggie Cam, Ping He, Stephen M. Hewitt, Xiaolin Wu, Snorri S. Thorgeirsson, Paul S. Meltzer, Christopher A. Loffredo, Robert H. Wiltrout, Curtis C. Harris, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin W. Wang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-173.
https://doi.org/10.1158/1538-7445.AM2015-LB-173
Published: 01 August 2015
View article titled, Abstract LB-173: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma
Journal Articles

Abstract 4873: IKKα bridges central tolerance to innate immunity and inflammation

Free
Feng Zhu, Zhisong Chen, Jami Willette-Brown, Dakshayani Lomada, Sean R. Davis, Timothy Back, Teizo Yoshimura, Zhonghe Sun, Xiaolin Wu, Robert Wiltrout, Ellen Richie, Ulrich Siebenlist, Giorgio Trichieri, Yinling Hu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4873.
https://doi.org/10.1158/1538-7445.AM2014-4873
Published: 01 October 2014
View article titled, Abstract 4873: IKKα bridges central tolerance to innate immunity and inflammation
Journal Articles

Abstract 1083: The pivotal role of IKKalpha in the development of spontaneous lung squamous cell carcinomas.

Free
Zuoxiang Xiao, Qun Jiang, Jami Willette-Brown, Feng Zhu, Sichuan Xi, Sandra Burkett, Fanching Lin, Timothy Back, Mahesh Datla, Zhonghe Sun, Romina Goldszmid, Xiaolin Wu, David Schrump, Howard Young, Georgio Trinchieri, Robert Wiltrout, Yinling Hu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1083.
https://doi.org/10.1158/1538-7445.AM2013-1083
Published: 15 April 2013
View article titled, Abstract 1083: The pivotal role of IKKalpha in the development of spontaneous lung squamous cell carcinomas.
Journal Articles

Abstract 772: Rap2b, a novel p53 downstream target, promotes cell survival after DNA damage.

Free
Yunlong He, Mangmang Li, Wendy Dubois, Alexander Kovalchuk, Xiaolin Wu, Jing Huang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 772.
https://doi.org/10.1158/1538-7445.AM2013-772
Published: 15 April 2013
View article titled, Abstract 772: Rap2b, a novel p53 downstream target, promotes cell survival after DNA damage.