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Xiaoju Wang
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Journal Articles

Abstract 3428: Discovery of a highly potent and selective dual PROTAC degrader of CDK12 and CDK13

Yu Chang, Jianzhang Yang, Jean Ching-Yi Tien, Zhen Wang, Yang Zhou, Pujuan Zhang, Weixue Huang, Josh Vo, Ingrid J. Apel, Cynthia Wang, Victoria Zhixuan Zeng, Yunhui Cheng, Shuqin Li, George Xiaoju Wang, Ke Ding, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3428.
https://doi.org/10.1158/1538-7445.AM2023-3428
Published: 04 April 2023
View articletitled, Abstract 3428: Discovery of a highly potent and selective dual PROTAC degrader of CDK12 and CDK13
Journal Articles

Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao, Pushpinder Bawa Pushpinder, Sanjana Eyunni, Rahul Mannan, Sandra E. Carson, Yu Chang, Xiaoju Wang, Yuping Zhang, Josh Vo, Steven Kregel, Stephanie A. Simko, Andrew D. Delekta, Mustapha Jaber, Heng Zheng, Ingrid Apel, Lisa McMurry, Fengyun Su, Rui Wang, Sylvia Wang, Sanjita Sasmal, Leena K. Satyam, Subhendu Mukherjee, Chandrasekhar AbbinenI, Kiran Aithal, Mital S. Bhakta, Jay Ghurye, Xuhong Cao, Nora M. Navone, Alexey Nesvizhskii, Rohit Mehra, Ulka Vaishampayan, Marco Blanchette, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5469.
https://doi.org/10.1158/1538-7445.AM2022-5469
Published: 15 June 2022
View articletitled, Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer
Journal Articles

Abstract 1278: Elucidating the mechanistic role of ERG in prostate cancer

Caleb Cheng, Lanbo Xiao, Jean Tien, Cynthia Wang, Jesse Cheng, Eileen Shiau, Xiaoju Wang, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1278.
https://doi.org/10.1158/1538-7445.AM2020-1278
Published: 15 August 2020
View articletitled, Abstract 1278: Elucidating the mechanistic role of ERG in prostate cancer
Journal Articles

Abstract 4153: Therapeutic targeting autophagy to sensitize cancer immunotherapy in various cancer types

Yuanyuan Qiao, Jae E. Choi, Josh N. Vo, Jean C. Tien, Lisha Wang, Lanbo Xiao, Stephanie A. Simko, Andrew D. Delekta, Nathan B. Hodge, Parth Desai, Kristin Juckette, Alice Xu, Fengyun Su, Rui Wang, Xuhong Cao, Xiaoju Wang, Xiaoming Wang, Javed Siddiqui, Zhen Wang, Amélie Bernard, Ester Fernandez-Salas, Nora M. Navone, Ke Ding, Eeva-Liisa Eskelinen, Elisabeth I. Heath, Daniel J. Klionsky, Weiping Zou, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4153.
https://doi.org/10.1158/1538-7445.AM2019-4153
Published: 01 July 2019
View articletitled, Abstract 4153: Therapeutic targeting autophagy to sensitize cancer immunotherapy in various cancer types
Journal Articles

Abstract 4497: Distinct structural classes of activating FOXA1 alterations in prostate cancer progression

Abhijit Parolia, Marcin Cieslik, Shih-Chun Chu, Lanbo Xiao, Takahiro Ouchi, Yuping Zhang, Xiaoju Wang, Pankaj Vats, Xuhong Cao, Fengyun Su, Rui Wang, Felix Feng, Yi-Mi Wu, Robert Lonigro, Dan R. Robinson, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4497.
https://doi.org/10.1158/1538-7445.AM2019-4497
Published: 01 July 2019
View articletitled, Abstract 4497: Distinct structural classes of activating FOXA1 alterations in prostate cancer progression
Journal Articles

Abstract 1418: Brother of regulator of imprinted sites (BORIS) inhibits cisplatin induced DNA damage in non-small-cell lung cancer

Yongfei Song, Chao Li, Mengdie Fang, Juan Ren, Jianfei Fang, Xiaoju Wang, Yanmei Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1418.
https://doi.org/10.1158/1538-7445.AM2019-1418
Published: 01 July 2019
View articletitled, Abstract 1418: Brother of regulator of imprinted sites (BORIS) inhibits cisplatin induced DNA damage in non-small-cell lung cancer
Journal Articles

Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer

Lanbo Xiao, Jean C. Tien, Josh Vo, Mengyao Tan, Abhijit Parolia, Yajia Zhang, Lisha Wang, Yuanyuan Qiao, Sudhanshu Shukla, Xiaoju Wang, Heng Zheng, Fengyun Su, Xiaojun Jing, Esther Luo, Andrew Delekta, Kristin M. Juckette, Alice Xu, Xuhong Cao, Ajjai S. Alva, Youngsoo Kim, A. Robert MacLeod, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5731–5740.
https://doi.org/10.1158/0008-5472.CAN-18-0941
Published: 15 October 2018
View articletitled, Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer
Open the PDF for Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1945: Degradation of ERG transcription factor as a targeted therapy in B-cell and T-cell acute lymphoblastic leukemia

Xiaoju Wang, Caleb Cheng, Yuanyuan Qiao, Lanbo Xiao, Cynthia Wang, Abhijit Parolia, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1945.
https://doi.org/10.1158/1538-7445.AM2018-1945
Published: 01 July 2018
View articletitled, Abstract 1945: Degradation of ERG transcription factor as a targeted therapy in B-cell and T-cell acute lymphoblastic leukemia
Journal Articles

Abstract 5834: Epigenetic re-programming sensitizes prostate cancer cells to anti-androgen therapy

Lanbo Xiao, Jean Ching-Yi Tien, Josh Vo, Abhijit Parolia, Lisha Wang, Mengyao Tan, Yuanyuan Qiao, Sudhanshu Shukla, Xiaoju Wang, Heng Zheng, Fengyun Su, Xuhong Cao, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5834.
https://doi.org/10.1158/1538-7445.AM2018-5834
Published: 01 July 2018
View articletitled, Abstract 5834: Epigenetic re-programming sensitizes prostate cancer cells to anti-androgen therapy
Journal Articles

Abstract 189: Development of peptidomimetic inhibitors of the ERG gene fusion product in prostate cancer

Xiaoju Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 189.
https://doi.org/10.1158/1538-7445.AM2017-189
Published: 01 July 2017
View articletitled, Abstract 189: Development of peptidomimetic inhibitors of the ERG gene fusion product in prostate cancer
Journal Articles

Abstract 3636: Targeting the MLL complex in castration resistant prostate cancer

Rohit Malik, Amjad P. Khan, Irfan A. Asangani, Marcin Cieślik, John R. Prensner, Xiaoju Wang, Matthew K. Iyer, Xia Jiang, Dmitry Borkin, June Escara-Wilke, Rachell Stender, Yi-Mi Wu, Xuhong Cao, Felix Y. Feng, Jolanta Grembecka, Tomasz Cierpicki, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3636.
https://doi.org/10.1158/1538-7445.AM2015-3636
Published: 01 August 2015
View articletitled, Abstract 3636: Targeting the MLL complex in castration resistant prostate cancer
Journal Articles

Abstract LB-058: Novel interactions of the RAS oncoprotein

Sunita Shankar, Rohit Malik, Vishal Kothari, Yasuyuki Hosono, Sethuramasundaram Pitchiaya, Shanker Kalyana-Sundaram, Anastasia Yocum, June Escara-Wilke, Harika Gundlapalli, Krishnapriya Chinnaswamy, Matthew Shuler, Anton Poliakov, Xiaoju Wang, Vishalakshi Krishnan, Yasmine White, Ari Firestone, Xuhong Cao, Saravana M. Dhanasekaran, Jeanne Stuckey, Gideon Bollag, Kevin Shannon, Nils G. Walter, Chandan Kumar-Sinha, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-058.
https://doi.org/10.1158/1538-7445.AM2015-LB-058
Published: 01 August 2015
View articletitled, Abstract LB-058: Novel interactions of the RAS oncoprotein
Journal Articles

Abstract 1398: Targeting novel co-activators of androgen receptor in castration resistant prostate cancer

Rohit Malik, Amjad P. Khan, John R. Prensner, Matthew K. Iyer, Dmitry Borkin, Xiaoju Wang, Xia Jiang, Shruthi Subramaniam, Yang Shi, Rachell Stender, Yi-Mi Wu, Xuhong Cao, Jolanta Grembecka, Tomasz Cierpicki, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1398.
https://doi.org/10.1158/1538-7445.AM2014-1398
Published: 01 October 2014
View articletitled, Abstract 1398: Targeting novel co-activators of androgen receptor in castration resistant prostate cancer
Journal Articles

Abstract LB-132: The central role of EED in orchestration of polycomb group complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Xuhong Cao, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-132.
https://doi.org/10.1158/1538-7445.AM2014-LB-132
Published: 01 October 2014
View articletitled, Abstract LB-132: The central role of EED in orchestration of polycomb group complexes
Journal Articles

Abstract 5535: Development of peptidomimetic inhibitors of the ERG transcription factor in prostate cancer.

Xiaoju Wang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5535.
https://doi.org/10.1158/1538-7445.AM2013-5535
Published: 15 April 2013
View articletitled, Abstract 5535: Development of peptidomimetic inhibitors of the ERG transcription factor in prostate cancer.
Journal Articles

Abstract 953: Mechanistic rationale for inhibition of Poly(ADP-Ribose) Polymerase in ETS gene fusion positive prostate cancer

J. Chad Brenner, Bushra Ateeq, Yong Li, Anastasia Yocum, Qi Cao, Irfan Asangani, Sonam Patel, Hallie Liang, Jindan Yu, Nallasivam Palanisamy, Javed Siddiqui, Wei Yan, Xiaoju Wang, Xuhong Cao, Rohit Mehra, Venkatesha Basrur, Robert Lonigro, Jun Yang, Scott Tomlins, Christopher Maher, Kojo Elenitoba-Johnson, Maha Hussain, Nora M. Navone, Kenneth Pienta, Sooryanarayana Varambally, Felix Y. Feng, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 953.
https://doi.org/10.1158/1538-7445.AM2011-953
Published: 15 April 2011
View articletitled, Abstract 953: Mechanistic rationale for inhibition of Poly(ADP-Ribose) Polymerase in ETS gene fusion positive prostate cancer
Journal Articles

A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome

Jindan Yu, Jianjun Yu, Daniel R. Rhodes, Scott A. Tomlins, Xuhong Cao, Guoan Chen, Rohit Mehra, Xiaoju Wang, Debashis Ghosh, Rajal B. Shah, Sooryanarayana Varambally, Kenneth J. Pienta, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10657–10663.
https://doi.org/10.1158/0008-5472.CAN-07-2498
Published: 15 November 2007
View articletitled, A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome
Open the PDF for A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome in another window
Includes: Supplementary data
Journal Articles

Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma

Guoan Chen, Xiaoju Wang, Jianjun Yu, Sooryanarayana Varambally, Jindan Yu, Dafydd G. Thomas, Mu-Yen Lin, Prakash Vishnu, Zhuwen Wang, Rui Wang, Jeff Fielhauer, Debashis Ghosh, Thomas J. Giordano, Donald Giacherio, Andrew C. Chang, Mark B. Orringer, Talal El-Hefnawy, William L. Bigbee, David G. Beer, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2007) 67 (7): 3461–3467.
https://doi.org/10.1158/0008-5472.CAN-06-4475
Published: 04 April 2007
View articletitled, Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma
Open the PDF for Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on Arrays

Madhumita Chatterjee, Saroj Mohapatra, Alexei Ionan, Gagandeep Bawa, Rouba Ali-Fehmi, Xiaoju Wang, James Nowak, Bin Ye, Fatimah A. Nahhas, Karen Lu, Steven S. Witkin, David Fishman, Adnan Munkarah, Robert Morris, Nancy K. Levin, Natalie N. Shirley, Gerard Tromp, Judith Abrams, Sorin Draghici, Michael A. Tainsky
Journal: Cancer Research
Cancer Res (2006) 66 (2): 1181–1190.
https://doi.org/10.1158/0008-5472.CAN-04-2962
Published: 19 January 2006
View articletitled, Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on Arrays
Open the PDF for Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on Arrays in another window
Includes: Supplementary data
Journal Articles

Humoral immune response profiles associated with diagnosis and prognosis in lung adenocarcinomas

Guoan Chen, Xiaoju Wang, Jianjun Yu, Sooryanarayana Varambally, Dafydd G. Thomas, Thomas J. Giordano, Andrew C. Chang, Arul M. Chinnaiyan, David G. Beer
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 944–945.
Published: 01 May 2005
View articletitled, Humoral immune response profiles associated with diagnosis and prognosis in lung adenocarcinomas