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Journal Articles

Targeting the PI3K/mTOR Pathway Augments CHK1 Inhibitor–Induced Replication Stress and Antitumor Activity in High-Grade Serous Ovarian Cancer

Tzu-Ting Huang, Ethan Brill, Jayakumar R. Nair, Xiaohu Zhang, Kelli M. Wilson, Lu Chen, Craig J. Thomas, Jung-Min Lee
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5380–5392.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-1439
Published: 02 December 2020
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Includes: Supplementary data
Journal Articles

Abstract 457: Discovery and characterization of GNF-7 as a preferentially cytotoxic compound for camptothecin-resistant Ewing sarcoma cells

Carly M. Sayers, Morgan B. Carter, Haiyan Lei, Steven Shema, Xiaohu Zhang, Kelli Wilson, Lu Chen, Craig J. Thomas, Jack F. Shern
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 457.
DOI: https://doi.org/10.1158/1538-7445.AM2020-457
Published: 15 August 2020
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Journal Articles

Abstract 621: Combined inhibition of checkpoint kinase 1 (CHK1) and phosphoinositide 3-kinase (PI3K) pathways induces greater replication stress and DNA damage in high-grade serous ovarian cancer (HGSOC)

Tzu-Ting Huang, Jayakumar Nair, Ethan Brill, Xiaohu Zhang, Kelli Wilson, Lu Chen, Craig J. Thomas, Jung-Min Lee
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 621.
DOI: https://doi.org/10.1158/1538-7445.AM2020-621
Published: 15 August 2020
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Journal Articles

Abstract 1169: Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutics

Darmood Wei, Youfeng Yang, Christopher J. Ricketts, Cathy D. Vocke, Mark W. Ball, Carole Sourbier, Darawalee Wangsa, Danny Wangsa, Rajarshi Guha, Xiaohu Zhang, Paul Meltzer, Thomas Reid, Craig J. Thomas, Maria J. Merino, W. Marston Linehan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1169.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1169
Published: 01 July 2018
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Journal Articles

Abstract 3065: High-throughput screen identifies HSP90 as a potential therapeutic target in models of advanced CRPC

Keith H. Jansson, John Tucker, Lauren Stahl, Caitlyn Fuller, Michael Beshiri, John K. Simmons, Supreet Agarwal, Lei Fang, Aian Neil Alilin, Ross Lake, Crystal Tran, Paul G. Hynes, Jacob Cawley, JuanJuan Yin, Xiaohu Zhang, Rajarshi Guha, Shelley Hoover, R. Mark Simpson, Holly Nguyen, Eva Corey, Craig Thomas, David Proia, Kathleen Kelly
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3065.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3065
Published: 01 July 2017
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Journal Articles

Abstract 278: No cell left behind: Residual ovarian spheroids drive recurrence and are sensitive to the pro-oxidant elesclomol

Ian S. Goldlust, Kelli Wilson, Ludmila Szabova, Xiaohu Zhang, Lesley Mathews-Griner, Maria Vias, Anna Piskorz, Rory Stark, Lee Mendil, Monica Kasbekar, John Braisted, Rajarshi Guha, Crystal McKnight, Paul Shinn, Donna Michelle-Smith, Zoe Weaver Ohler, Mindy Davis, Udo Rudloff, Sam Michael, Madhu Lal-Nag, Scott Martin, Christina Annunziata, Marc Ferrer, James D. Brenton, Craig Thomas
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 278.
DOI: https://doi.org/10.1158/1538-7445.AM2016-278
Published: 15 July 2016
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Journal Articles

Abstract LB-281: Elucidating potential therapeutic targets in a model of Pten/Tp53 null prostate cancer using high-throughput screening technology

Keith H. Jansson, John K. Simmons, Caitlyn Fuller, Supreet Agarwal, Paul G. Hynes, Lei Fang, Ross Lake, Jacob Cawley, Lauren Stahl, Xiaohu Zhang, Rajarshi Guha, Craig Thomas, Kathleen Kelly
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-281.
DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-281
Published: 15 July 2016
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Journal Articles

Abstract PR16: Targeting the chromatin architecture established by PAX3-FOXO1 in rhabdomyosarcoma

Berkley E. Gryder, Marielle E. Yohe, Jack Shern, Hsien-Chao Chou, Young Song, Rajesh Patidar, Sam Li, Sivasish Sindiri, Abigail Cleveland, Hongling Liao, Xinyu Wen, Xiaohu Zhang, Lesley Mathews-Griner, Rajarshi Guha, Paul Shinn, Marc Ferrer, Scott Martin, Madhu Lal, Craig Thomas, Javed Khan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): PR16.
DOI: https://doi.org/10.1158/1538-7445.PEDCA15-PR16
Published: 04 April 2016
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Journal Articles

Abstract A25: Reprogramming RAS-driven rhabdomyosarcoma via MEK inhibition

Marielle E. Yohe, Berkley E. Gryder, Jack F. Shern, Young K. Song, Hongling Liao, Hsein-Chao Chou, Sivasish Sindiri, Arnulfo Mendoza, Xiaohu Zhang, Rajarashi Guha, Diana C. Haines, James P. Madigan, Jun S. Wei, Marc Ferrer, Craig J. Thomas, Javed Khan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): A25.
DOI: https://doi.org/10.1158/1538-7445.PEDCA15-A25
Published: 04 April 2016
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Journal Articles

The cis Decoy against the Estrogen Response Element Suppresses Breast Cancer Cells via Target Disrupting c-fos not Mitogen-activated Protein Kinase Activity

Li Hua Wang, Xiao Yi Yang, Xiaohu Zhang, Kelly Mihalic, Weihua Xiao, William L. Farrar
Journal: Cancer Research
Cancer Res (2003) 63 (9): 2046–2051.
Published: 01 May 2003
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