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Journal Articles

Abstract 3585: Probing the relationship between renal carcinoma perfusion, hypoxia, and metabolism during response to VEGFR inhibition and at resistance

Qianhui Dou, Patricia Coutinho de Souza, Xiaoen Wang, Aaron K. Grant, Leo L. Tsai
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3585.
https://doi.org/10.1158/1538-7445.AM2023-3585
Published: 04 April 2023
View article titled, Abstract 3585: Probing the relationship between renal carcinoma perfusion, hypoxia, and metabolism during response to VEGFR inhibition and at resistance
Journal Articles

Abstract 2945: Novel engineered B-NDG B2M/KO mice plus and steroid treated B-NDG Mice shows delayed GvHD response when engrafted with hPBMC

Lan Gao, Shruti Sharma, Eugene Lin, Xiaoen Wang, Chengzhang Shang, Yuting Hu, W. Frank An, Mehma Kaur Chawla, Kaiqi Li, Qingcong Lin, Zhaoxue (Luke) Yu, Yujie Liu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2945.
https://doi.org/10.1158/1538-7445.AM2021-2945
Published: 01 July 2021
View article titled, Abstract 2945: Novel engineered B-NDG B2M/KO mice plus and steroid treated B-NDG Mice shows delayed GvHD response when engrafted with hPBMC
Journal Articles

Abstract 432: Development of a novel engineered B2M mouse strain on B-NDG background that specifically eliminates MHC I expression while retaining normal FcRn-mediated antibody retention

W. Frank An, Lan Gao, Xiaoen Wang, Shruti Sharma, Kaiqi Li, Xiqiang Gao, Chengzhang Shang, Yuting Hu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 432.
https://doi.org/10.1158/1538-7445.AM2020-432
Published: 15 August 2020
View article titled, Abstract 432: Development of a novel engineered B2M mouse strain on B-NDG background that specifically eliminates MHC I expression while retaining normal FcRn-mediated antibody retention
Journal Articles

Abstract 4060: Discovery and preclinical development of KRAS-targeting siRNA therapeutic modality for the treatment of pancreatic cancer

Zhihong (Julie) OBrien, Li Wang, Cima Cina, Bharat Majeti, James Chu, Xiaoen Wang, Robiel Baclig, James Lin, Jose Ibarra, Dhrubamitra Chatterjee, Jung-Kang Jin, Jean-Pierre Clamme, Jennifer Daniels, Hai Wang, Jens Harborth, Wenbin Ying
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4060.
https://doi.org/10.1158/1538-7445.AM2020-4060
Published: 15 August 2020
View article titled, Abstract 4060: Discovery and preclinical development of KRAS-targeting siRNA therapeutic modality for the treatment of pancreatic cancer
Journal Articles

NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model

Yan Liu, Yuyang Li, Shengwu Liu, Dennis O. Adeegbe, Camilla L. Christensen, Max M. Quinn, Ruben Dries, Shiwei Han, Kevin Buczkowski, Xiaoen Wang, Ting Chen, Peng Gao, Hua Zhang, Fei Li, Peter S. Hammerman, James E. Bradner, Steven N. Quayle, Kwok-Kin Wong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3709–3717.
https://doi.org/10.1158/0008-5472.CAN-18-0161
Published: 01 July 2018
View article titled, NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model
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Includes: Supplementary data
Journal Articles

Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma

Yan Liu, Yuyang Li, Xiaoen Wang, Feiyang Liu, Peng Gao, Max M. Quinn, Fei Li, Ashley A. Merlino, Cyril Benes, Qingsong Liu, Nathanael S. Gray, Kwok-Kin Wong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (18): 5068–5076.
https://doi.org/10.1158/0008-5472.CAN-17-0567
Published: 14 September 2017
View article titled, Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract 5080: Inhibiting the ALK1/BMP9 signaling pathway with dalantercept as an antiangiogenic therapy.

Marat Alimzhanov, Nicolas Solban, Michael Lee, Phaethon Philbrook, Xiaoen Wang, Lin Wei, Jiaxi Song, Sabina Signoretti, R. Scott Pearsall, Matthew L. Sherman, Ravindra Kumar, Rupal S. Bhatt
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5080.
https://doi.org/10.1158/1538-7445.AM2013-5080
Published: 15 April 2013
View article titled, Abstract 5080: Inhibiting the ALK1/BMP9 signaling pathway with dalantercept as an antiangiogenic therapy.
Journal Articles

Abstract 1608: Angiopoietin 2 is elevated in patients with RCC, and Ang2 inhibition improves antiantiogenic activity of sunitinib in a mouse model of RCC.

Xiaoen Wang, Andrea Bullock, Liang Zhang, Dongyin Yu, Lin Wei, Jiaxi Song, Manoj Bhasin, Sabina Signoretti, David C. Alsop, James W. Mier, Michael B. Atkins, Angela Coxon, Jon Oliner, Rupal S. Bhatt
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1608.
https://doi.org/10.1158/1538-7445.AM2013-1608
Published: 15 April 2013
View article titled, Abstract 1608: Angiopoietin 2 is elevated in patients with RCC, and Ang2 inhibition improves antiantiogenic activity of sunitinib in a mouse model of RCC.
Journal Articles

Abstract LB-313: ALK1-Fc inhibits tumor growth in a VEGF pathway resistance model of renal cell carcinoma

Xiaoen Wang, Nicolas Solban, Manoj K. Bhasin, Brittany Bahamon, Liang Zhang, Sabina Signoretti, David C. Alsop, Michael B. Atkins, R. Scott Pearsall, James W. Mier, Ravindra Kumar, Rupal S. Bhatt
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-313.
https://doi.org/10.1158/1538-7445.AM2012-LB-313
Published: 15 April 2012
View article titled, Abstract LB-313: ALK1-Fc inhibits tumor growth in a VEGF pathway resistance model of renal cell carcinoma
Journal Articles

Abstract 579: Chinese herbal mixture LQ inhibits tumor growth and metastasis and increases survival in orthotopic and other mouse models of human and mouse cancer

Lei Zhang, Chengyu Wu, Yong Zhang, Xiaoen Wang, Jose Reynoso, Fang Liu, Ming Zhao, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 579.
https://doi.org/10.1158/1538-7445.AM10-579
Published: 15 April 2010
View article titled, Abstract 579: Chinese herbal mixture LQ inhibits tumor growth and metastasis and increases survival in orthotopic and other mouse models of human and mouse cancer
Journal Articles

Abstract LB-369: Sphingosine-1-phosphate (S1P) as a novel target in renal cancer (RCC)

Rupal S. Bhatt, Liang Zhang, Andrea Bullock, Xiaoen Wang, Kelli Moreno, Sabina Signoretti, Michael B. Atkins, Roger Sabbadini, James W. Mier
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-369.
https://doi.org/10.1158/1538-7445.AM10-LB-369
Published: 15 April 2010
View article titled, Abstract LB-369: Sphingosine-1-phosphate (S1P) as a novel target in renal cancer (RCC)
Journal Articles

Abstract #153: Cox-2 inhibition delays resistance to sunitinib in RCC xenograft models

Rupal Bhatt, Xiaoen Wang, Liang Zhang, Andrea Bullock, Manoj Bhasin, Towia Libermann, Sabina Signoretti, Anne O'Neill, Michael Atkins, James Mier, S. Goldberg
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 153.
Published: 01 May 2009
View article titled, Abstract #153: Cox-2 inhibition delays resistance to sunitinib in RCC xenograft models
Journal Articles

Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate

Zhijian Yang, Xinghua Sun, Shukuan Li, Yuying Tan, Xiaoen Wang, Nan Zhang, Shigeo Yagi, Tomoaki Takakura, Yoshinao Kobayashi, Akio Takimoto, Takayuki Yoshioka, Akinori Suginaka, Eugene P. Frenkel, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5775–5778.
https://doi.org/10.1158/0008-5472.CAN-04-1406
Published: 16 August 2004
View article titled, Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate
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Journal Articles

In vivo stabilization of polyethylene glycol (PEG)-modified recombinant methioninase (rMETase) activity by pyridoxal phosphate

Xinghua Sun, Zhijian Yang, Shukuan Li, Yuying Tan, Nan Zhang, Xiaoen Wang, Shigeo Yagi, Takayuki Yoshioka, Akinori Suginaka, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 234.
Published: 01 April 2004
View article titled, <em>In vivo</em> stabilization of polyethylene glycol (PEG)-modified recombinant methioninase (rMETase) activity by pyridoxal phosphate
Journal Articles

In Vivo Efficacy of Recombinant Methioninase Is Enhanced by the Combination of Polyethylene Glycol Conjugation and Pyridoxal 5′-Phosphate Supplementation

Xinghua Sun, Zhijian Yang, Shukuan Li, Yuying Tan, Nan Zhang, Xiaoen Wang, Shigeo Yagi, Takayuki Yoshioka, Akio Takimoto, Kenji Mitsushima, Akinori Suginaka, Eugene P. Frenkel, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2003) 63 (23): 8377–8383.
Published: 16 December 2003
View article titled, <em>In Vivo</em> Efficacy of Recombinant Methioninase Is Enhanced by the Combination of Polyethylene Glycol Conjugation and Pyridoxal 5′-Phosphate Supplementation
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Journal Articles

Widespread Skeletal Metastatic Potential of Human Lung Cancer Revealed by Green Fluorescent Protein Expression

Meng Yang, Satoshi Hasegawa, Ping Jiang, Xiaoen Wang, Yuying Tan, Takashi Chishima, Hiroshi Shimada, A. R. Moossa, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (1998) 58 (19): 4217–4221.
Published: 01 October 1998
View article titled, Widespread Skeletal Metastatic Potential of Human Lung Cancer Revealed by Green Fluorescent Protein Expression
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Journal Articles

Cancer Invasion and Micrometastasis Visualized in Live Tissue by Green Fluorescent Protein Expression

Takashi Chishima, Yohei Miyagi, Xiaoen Wang, Hiroyuki Yamaoka, Hiroshi Shimada, A. R. Moossa, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (1997) 57 (10): 2042–2047.
Published: 01 May 1997
View article titled, Cancer Invasion and Micrometastasis Visualized in Live Tissue by Green Fluorescent Protein Expression
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