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Journal Articles

Abstract 6064: Multiomics preclinical characterization of SAR445877, an anti-PD-1 antibody-IL-15 mutein fusion protein with robust anti-tumor efficacy as monotherapy

Free
Julien Tessier, Joon Sang Lee, Ingeborg M. Langohr, Caroline Morel, Xiangming Li, Seth Garren, Virna Cortez-Retamozo, Dinesh Bangari, Donald Jackson, Donald Shaffer, Angela Hadjipanayis
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6064.
https://doi.org/10.1158/1538-7445.AM2025-6064
Published: 21 April 2025
View articletitled, Abstract 6064: Multiomics preclinical characterization of SAR445877, an anti-PD-1 antibody-IL-15 mutein fusion protein with robust anti-tumor efficacy as monotherapy
Journal Articles

Abstract 2469: PROTAC mediated NR4A1 degradation as a novel strategy for cancer immunotherapy

Free
Lei Wang, Yufeng Xiao, Yuewan Luo, Rohan Master, Jiao Mo, Myung-Chul Kim, Yi Liu, Chandra Maharjan, Urvi Patel, Xiangming Li, Donald Shaffer, Guertin Kevin, Haoyang Zhuang, Emily Moser, Keiran Smalley, Daohong Zhou, Guangrong Zheng, Weizhou Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2469.
https://doi.org/10.1158/1538-7445.AM2024-2469
Published: 22 March 2024
View articletitled, Abstract 2469: PROTAC mediated NR4A1 degradation as a novel strategy for cancer immunotherapy
Journal Articles

Abstract 4063: SAR445877, an anti-PD-1 antibody-IL-15 mutein fusion protein restores function to exhausted T cells

Free
Isaraphorn Pratumchai, Marie Bernardo, Kristi Lynn Marquardt, Chen Zhu, Fatima Menas, Roberto Carrio, Tony Byers, Donald Shaffer, Xiangming Li, John Ross Teijaro
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4063.
https://doi.org/10.1158/1538-7445.AM2024-4063
Published: 22 March 2024
View articletitled, Abstract 4063: SAR445877, an anti-PD-1 antibody-IL-15 mutein fusion protein restores function to exhausted T cells
Journal Articles

Abstract 2053: Spatiotemporal tumor immune modulation by localized delivery of cancer therapeutics using an implantable microdevice

Free
Xiangming Li, Julien Tessier, Joon Sang Lee, Seth Garren, Virna Cortez-Retamozo, Meenu Sharma, Angela Jankowski, Erik Zarazinski, Ann Fiore, Oliver Jonas, Colin Brenan, Donald Shaffer, Angela Hadjipanayis
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2053.
https://doi.org/10.1158/1538-7445.AM2024-2053
Published: 22 March 2024
View articletitled, Abstract 2053: Spatiotemporal tumor immune modulation by localized delivery of cancer therapeutics using an implantable microdevice
Journal Articles

Abstract 2972: Preclinical characterization of SAR445877, an anti-PD-1 antibody-IL-15 mutein fusion protein with robust anti-tumor efficacy as monotherapy and in combination with PD-L1 blockade

Free
Marie Bernardo, Yu-an Zhang, Dan Lu, Stella Martomo, Fatima Menas, Chen Zhu, Raymond Perez, Jeegar Patel, Donald Shaffer, Xiangming Li
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2972.
https://doi.org/10.1158/1538-7445.AM2023-2972
Published: 04 April 2023
View articletitled, Abstract 2972: Preclinical characterization of SAR445877, an anti-PD-1 antibody-IL-15 mutein fusion protein with robust anti-tumor efficacy as monotherapy and in combination with PD-L1 blockade
Journal Articles

Abstract 3580: Noninvasive immuno-PET imaging of CD8+T cell behavior in tumor bearing mice models treated with SAR444245

Free
Sebastion d'Heilly, Fabrice Tirode, Maxime Gaulin, Dudzicki Anne, Guillaume Bluet, Stéphane Guerif, Francis Descamps, Peter Casteels, Xiangming Li, Rui Wang, Robin Meng, Erwan Jouannot
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3580.
https://doi.org/10.1158/1538-7445.AM2023-3580
Published: 04 April 2023
View articletitled, Abstract 3580: Noninvasive immuno-PET imaging of CD8+T cell behavior in tumor bearing mice models treated with SAR444245
Journal Articles

Abstract 1711: Induction of anti-tumor immunity by intratumoral delivery of mRNA encoding cytokines and TNFRSF agonists

Free
Julie-Ann Gavigan, Chaomei Shi, Michael Lampa, Natalia Malkova, Qunyan Yu, Hui Qu, Mikhail Levit, Timothy Wagenaar, Christian Hotz, Xiangming Li
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1711.
https://doi.org/10.1158/1538-7445.AM2021-1711
Published: 01 July 2021
View articletitled, Abstract 1711: Induction of anti-tumor immunity by intratumoral delivery of mRNA encoding cytokines and TNFRSF agonists
Journal Articles

Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer

Free
Tonya J. Webb, Xiangming Li, Robert L. Giuntoli, II, Pablo H.H. Lopez, Christoph Heuser, Ronald L. Schnaar, Moriya Tsuji, Christian Kurts, Mathias Oelke, Jonathan P. Schneck
Journal: Cancer Research
Cancer Res (2012) 72 (15): 3744–3752.
https://doi.org/10.1158/0008-5472.CAN-11-2695
Published: 31 July 2012
View articletitled, Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer
Open the PDF for Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer in another window
Includes: Supplementary data