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Xiangchun Li
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Journal Articles

CRTC2 Forms Co-condensates with YTHDF2 that Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance

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Meixi Wang, Fangdi Zou, Shengxin Wang, Yichen Yang, Cong Xia, Lu Chen, Ben Liu, Lian Li, Mulin Jun Li, Haixin Li, Weijie Song, Ruifang Niu, Zhiyong Yuan, Jie Yang, Xiangchun Li, Kexin Chen, Zhiqiang Wu, Zeyun Mi
Journal: Cancer Research
Cancer Res (2025)
https://doi.org/10.1158/0008-5472.CAN-24-3196
Published: 04 March 2025
View articletitled, CRTC2 Forms Co-condensates with YTHDF2 that Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance
Open the PDF for CRTC2 Forms Co-condensates with YTHDF2 that Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance in another window
Includes: Supplementary data
Journal Articles

Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution

Free
Xiansong Wang, Wei Hu, Xiangchun Li, Dan Huang, Qing Li, Hung Chan, Judeng Zeng, Chuan Xie, Huarong Chen, Xiaodong Liu, Tony Gin, Maggie Haitian Wang, Alfred Sze Lok Cheng, Wei Kang, Ka-Fai To, Dariusz Plewczynski, Qingpeng Zhang, Xiaoting Chen, Danny Cheuk Wing Chan, Ho Ko, Sunny Hei Wong, Jun Yu, Matthew Tak Vai Chan, Lin Zhang, William Ka Kei Wu
Journal: Cancer Research
Cancer Res (2022) 82 (8): 1482–1491.
https://doi.org/10.1158/0008-5472.CAN-21-3458
Published: 15 April 2022
View articletitled, Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution
Open the PDF for Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution in another window
Includes: Supplementary data
Journal Articles

Abstract 3558: Interrogation of onco-microRNA 125b reveals androgen receptor as a key upstream transcriptional factor that is targetable in female gastric cancer

Free
Ben Liu, Meng Zhou, Da Yang, Qinghua Wang, Qiang Zhang, Xiangchun Li, Meng Yang, Qiong Wang, Lian Li, Luyang Liu, Hongji Dai, Fengju Song, Hong Zheng, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3558.
https://doi.org/10.1158/1538-7445.AM2019-3558
Published: 01 July 2019
View articletitled, Abstract 3558: Interrogation of onco-microRNA 125b reveals androgen receptor as a key upstream transcriptional factor that is targetable in female gastric cancer
Journal Articles

Abstract 1394: Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images from clinical ultrasound exams

Free
Xiangchun Li, Sheng Zhang, Qiang Zhang, Xi Wei, Yi Pan, Jing Zhao, Xiaojie Xin, Xiaoqing Wang, Fan Yang, Jianxin Li, Meng Yang, Qinghua Wang, Xiangqian Zheng, Yanhui Zhao, Lun Zhang, Xudong Wang, Zhimin Zheng, Christopher T. Whitlow, Metin N. Gurcan, Boris Pasche, Ming Gao, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1394.
https://doi.org/10.1158/1538-7445.AM2019-1394
Published: 01 July 2019
View articletitled, Abstract 1394: Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images from clinical ultrasound exams
Journal Articles

Abstract 4412: Elevated miR-193a attenuates 5-fluorouricil metabolism enzyme CMPK1, resulting in therapeutic resistance and poor survival in gastric cancer

Free
Hao Chen, Wei Wang, Ben Liu, Lu Han, Xinlei Chu, Hong Zheng, Yanrui Zhao, Xiangchun Li, Lian li, Fengju Song, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4412.
https://doi.org/10.1158/1538-7445.AM2018-4412
Published: 01 July 2018
View articletitled, Abstract 4412: Elevated miR-193a attenuates 5-fluorouricil metabolism enzyme CMPK1, resulting in therapeutic resistance and poor survival in gastric cancer
Journal Articles

Abstract 3405: A mutational signature associated with alcohol consumption and prognostically mutated driver genes in esophageal squamous cell carcinoma

Free
Xiangchun Li, Mengyao Wang, Meng Yang, Hongji Dai, Baifeng Zhang, Wei Wang, Xinlei Chu, Xin Wang, Hong Zheng, Ruifang Niu, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3405.
https://doi.org/10.1158/1538-7445.AM2018-3405
Published: 01 July 2018
View articletitled, Abstract 3405: A mutational signature associated with alcohol consumption and prognostically mutated driver genes in esophageal squamous cell carcinoma
Journal Articles

RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3

Free
Lei Liu, Yanquan Zhang, Chi Chun Wong, Jingwan Zhang, Yujuan Dong, Xiangchun Li, Wei Kang, Francis K.L. Chan, Joseph J.Y. Sung, Jun Yu
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (8): 1958–1971.
https://doi.org/10.1158/0008-5472.CAN-17-2683
Published: 12 April 2018
View articletitled, RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3
Open the PDF for RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3 in another window
Includes: Supplementary data
Journal Articles

Abstract 154: Defective calcium signaling pathway highlights the mutational landscapes of liver metastasis from colorectal and breast cancer

Free
Fangfang Song, Xiangchun Li, Yuexin Liu, Hong Zheng, Haixin Li, Jun Wang, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 154.
https://doi.org/10.1158/1538-7445.AM2016-154
Published: 15 July 2016
View articletitled, Abstract 154: Defective calcium signaling pathway highlights the mutational landscapes of liver metastasis from colorectal and breast cancer
Journal Articles

Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability

Free
Xiangchun Li, William K.K. Wu, Rui Xing, Sunny H. Wong, Yuexin Liu, Xiaodong Fang, Yanlin Zhang, Mengyao Wang, Jiaqian Wang, Lin Li, Yong Zhou, Senwei Tang, Shaoliang Peng, Kunlong Qiu, Longyun Chen, Kexin Chen, Huanming Yang, Wei Zhang, Matthew T.V. Chan, Youyong Lu, Joseph J.Y. Sung, Jun Yu
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (7): 1724–1732.
https://doi.org/10.1158/0008-5472.CAN-15-2443
Published: 31 March 2016
View articletitled, Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability
Open the PDF for Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability in another window
Includes: Supplementary data
Journal Articles

Abstract B38: Whole exome sequencing of 101 neuroblastomas with distinct genomic subgroups identified significantly mutated pathways in aggressive tumor subtypes

Free
Miki Ohira, Yuanyuan Li, Yong Zhou, Xiangchun Li, Zhibo Gao, Kenji Tatsuno, Shuichi Tsutsumi, Shogo Yamamoto, Yohko Nakamura, Takehiko Kamijo, Hiroyuki Aburatani, Akira Nakagawara
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): B38.
https://doi.org/10.1158/1538-7445.PEDCAN-B38
Published: 09 October 2014
View articletitled, Abstract B38: Whole exome sequencing of 101 neuroblastomas with distinct genomic subgroups identified significantly mutated pathways in aggressive tumor subtypes