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Xiang-Yang Wang
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Journal Articles

The Innate Immune System and the TRAIL–Bcl-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females

Lauren May, Bin Hu, Preksha Jerajani, Akash Jagdeesh, Ohud Alhawiti, Lillian Cai, Nina Semenova, Chunqing Guo, Madison Isbell, Xiaoyan Deng, Anthony C. Faber, Raghavendra Pillappa, Dipankar Bandyopadhyay, Xiang-Yang Wang, Alexander Neuwelt, Jennifer Koblinski, Paula D. Bos, Howard Li, Rebecca Martin, Joseph W. Landry
Journal: Cancer Research
Cancer Res (2024) 84 (24): 4140–4155.
https://doi.org/10.1158/0008-5472.CAN-24-0585
Published: 16 December 2024
View article titled, The Innate Immune System and the TRAIL–Bcl-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females
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Includes: Supplementary data
Journal Articles

Abstract 3394: Simultaneous targeting of the PDZ1 and PDZ2 domains of MDA-9 inhibits melanoma metastasis

Anjan K. Pradhan, Jinkal Modi, Santanu Maji, Amit Kumar, Praveen Bhoopathi, Padmanabhan Mannangatti, Chunqing Guo, Daniel K. Afosah, Mark Mochel, Nitai D. Mukhopadhyay, John M. Kirkwood, Xiang-Yang Wang, Umesh R. Desai, Devanand Sarkar, Luni Emdad, Swadesh K. Das, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3394.
https://doi.org/10.1158/1538-7445.AM2023-3394
Published: 04 April 2023
View article titled, Abstract 3394: Simultaneous targeting of the PDZ1 and PDZ2 domains of MDA-9 inhibits melanoma metastasis
Journal Articles

Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer

Cynthia Weigel, Melissa A. Maczis, Elisa N.D. Palladino, Christopher D. Green, Michael Maceyka, Chunqing Guo, Xiang-Yang Wang, Mikhail G. Dozmorov, Sheldon Milstien, Sarah Spiegel
Journal: Cancer Research
Cancer Res (2023) 83 (4): 553–567.
https://doi.org/10.1158/0008-5472.CAN-22-1638
Published: 15 February 2023
View article titled, Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
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Includes: Supplementary data
Journal Articles

Engineering T Cells to Express Tumoricidal MDA-7/IL24 Enhances Cancer Immunotherapy

Zheng Liu, Chunqing Guo, Swadesh K. Das, Xiaofei Yu, Anjan K. Pradhan, Xia Li, Yanxia Ning, Shixian Chen, Wenjie Liu, Jolene J. Windle, Harry D. Bear, Masoud H. Manjili, Paul B. Fisher, Xiang-Yang Wang
Journal: Cancer Research
Cancer Res (2021) 81 (9): 2429–2441.
https://doi.org/10.1158/0008-5472.CAN-20-2604
Published: 01 May 2021
View article titled, Engineering T Cells to Express Tumoricidal MDA-7/IL24 Enhances Cancer Immunotherapy
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Includes: Supplementary data
Journal Articles

IGFBP7 Deletion Promotes Hepatocellular Carcinoma

Maaged Akiel, Chunqing Guo, Xia Li, Devaraja Rajasekaran, Rachel G. Mendoza, Chadia L. Robertson, Nidhi Jariwala, Fang Yuan, Mark A. Subler, Jolene Windle, Dawn K. Garcia, Zhao Lai, Hung-I Harry Chen, Yidong Chen, Shah Giashuddin, Paul B. Fisher, Xiang-Yang Wang, Devanand Sarkar
Journal: Cancer Research
Cancer Res (2017) 77 (15): 4014–4025.
https://doi.org/10.1158/0008-5472.CAN-16-2885
Published: 01 August 2017
View article titled, IGFBP7 Deletion Promotes Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity

Kimberly Mayes, Suehyb G. Alkhatib, Kristen Peterson, Aiman Alhazmi, Carolyn Song, Vivian Chan, Tana Blevins, Mark Roberts, Catherine I. Dumur, Xiang-Yang Wang, Joseph W. Landry
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6183–6192.
https://doi.org/10.1158/0008-5472.CAN-15-3125
Published: 31 October 2016
View article titled, BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Activation of the MDA-5–IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity

Xiaofei Yu, Hongxia Wang, Xia Li, Chunqing Guo, Fang Yuan, Paul B. Fisher, Xiang-Yang Wang
Journal: Cancer Research
Cancer Res (2016) 76 (8): 2166–2176.
https://doi.org/10.1158/0008-5472.CAN-15-2142
Published: 14 April 2016
View article titled, Activation of the MDA-5–IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Genetic Deletion of AEG-1 Prevents Hepatocarcinogenesis

Chadia L. Robertson, Jyoti Srivastava, Ayesha Siddiq, Rachel Gredler, Luni Emdad, Devaraja Rajasekaran, Maaged Akiel, Xue-Ning Shen, Chunqing Guo, Shah Giashuddin, Xiang-Yang Wang, Shobha Ghosh, Mark A. Subler, Jolene J. Windle, Paul B. Fisher, Devanand Sarkar
Journal: Cancer Research
Cancer Res (2014) 74 (21): 6184–6193.
https://doi.org/10.1158/0008-5472.CAN-14-1357
Published: 30 October 2014
View article titled, Genetic Deletion of AEG-1 Prevents Hepatocarcinogenesis
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Includes: Supplementary data
Journal Articles

A Multifunctional Chimeric Chaperone Serves as a Novel Immune Modulator Inducing Therapeutic Antitumor Immunity

Xiaofei Yu, Chunqing Guo, Huanfa Yi, Jie Qian, Paul B. Fisher, John R. Subjeck, Xiang-Yang Wang
Journal: Cancer Research
Cancer Res (2013) 73 (7): 2093–2103.
https://doi.org/10.1158/0008-5472.CAN-12-1740
Published: 02 April 2013
View article titled, A Multifunctional Chimeric Chaperone Serves as a Novel Immune Modulator Inducing Therapeutic Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Abstract 61: A new serotype chimera Cancer Terminator Virus (Ad.5/3-CTV) expands the efficiency and specificity of prostate cancer gene transfer and therapy

Belal Azab, Rupesh Dash, Swadesh Das, Sujit Bhutia, Xue-Ning Shen, Bridget Quinn, Santanu Dasgupta, Paul Dent, Igor Dmitriev, Xiang-Yang Wang, David Curiel, Steven Grant, Maurizio Pellecchia, John Reed, Devanand Sarkar, Paul Fisher
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 61.
https://doi.org/10.1158/1538-7445.AM2012-61
Published: 15 April 2012
View article titled, Abstract 61: A new serotype chimera Cancer Terminator Virus (Ad.5/3-CTV) expands the efficiency and specificity of prostate cancer gene transfer and therapy
Journal Articles

Targeting the Immunoregulator SRA/CD204 Potentiates Specific Dendritic Cell Vaccine-Induced T-cell Response and Antitumor Immunity

Huanfa Yi, Chunqing Guo, Xiaofei Yu, Ping Gao, Jie Qian, Daming Zuo, Masoud H. Manjili, Paul B. Fisher, John R. Subjeck, Xiang-Yang Wang
Journal: Cancer Research
Cancer Res (2011) 71 (21): 6611–6620.
https://doi.org/10.1158/0008-5472.CAN-11-1801
Published: 30 October 2011
View article titled, Targeting the Immunoregulator SRA/CD204 Potentiates Specific Dendritic Cell Vaccine-Induced T-cell Response and Antitumor Immunity
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Journal Articles

Secretable Chaperone Grp170 Enhances Therapeutic Activity of a Novel Tumor Suppressor, mda-7/IL-24

Ping Gao, Xiaolei Sun, Xing Chen, Yanping Wang, Barbara A. Foster, John Subjeck, Paul B. Fisher, Xiang-Yang Wang
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3890–3898.
https://doi.org/10.1158/0008-5472.CAN-08-0156
Published: 15 May 2008
View article titled, Secretable Chaperone Grp170 Enhances Therapeutic Activity of a Novel Tumor Suppressor, <em>mda-7</em>/IL-24
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Journal Articles

Scavenger Receptor-A Negatively Regulates Antitumor Immunity

Xiang-Yang Wang, John Facciponte, Xing Chen, John R. Subjeck, Elizabeth A. Repasky
Journal: Cancer Research
Cancer Res (2007) 67 (10): 4996–5002.
https://doi.org/10.1158/0008-5472.CAN-06-3138
Published: 17 May 2007
View article titled, Scavenger Receptor-A Negatively Regulates Antitumor Immunity
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Journal Articles

Chaperoning Function of Stress Protein grp170, a Member of the hsp70 Superfamily, Is Responsible for its Immunoadjuvant Activity

Jun-Eui Park, John Facciponte, Xing Chen, Ian MacDonald, Elizabeth A. Repasky, Masoud H. Manjili, Xiang-Yang Wang, John R. Subjeck
Journal: Cancer Research
Cancer Res (2006) 66 (2): 1161–1168.
https://doi.org/10.1158/0008-5472.CAN-05-2609
Published: 19 January 2006
View article titled, Chaperoning Function of Stress Protein grp170, a Member of the hsp70 Superfamily, Is Responsible for its Immunoadjuvant Activity
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Journal Articles

Targeted Immunotherapy Using Reconstituted Chaperone Complexes of Heat Shock Protein 110 and Melanoma-associated Antigen gp100

Xiang-Yang Wang, Xing Chen, Masoud H. Manjili, Elizabeth Repasky, Robert Henderson, John R. Subjeck
Journal: Cancer Research
Cancer Res (2003) 63 (10): 2553–2560.
Published: 15 May 2003
View article titled, Targeted Immunotherapy Using Reconstituted Chaperone Complexes of Heat Shock Protein 110 and Melanoma-associated Antigen gp100
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Journal Articles

Development of a Recombinant HSP110-HER-2/ neu Vaccine Using the Chaperoning Properties of HSP110

Masoud H. Manjili, Robert Henderson, Xiang-Yang Wang, Xing Chen, Ying Li, Elizabeth Repasky, Latif Kazim, John R. Subjeck
Journal: Cancer Research
Cancer Res (2002) 62 (6): 1737–1742.
Published: 15 March 2002
View article titled, Development of a Recombinant HSP110-HER-2/ <em>neu</em> Vaccine Using the Chaperoning Properties of HSP110
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