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Xiang H.-F. Zhang
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Journal Articles

Abstract 386: Metastatic models of resistance to next generation tyrosine kinase inhibitors (TKIs) in HER2-positive breast cancer (BC)

Fu-Tien Liao, Lanfang Qin, Martin J. Shea, Igor Bado, Yi-Hsuan Wu, Ling Wu, Yang Gao, Sarmistha Nanda, Tia Gordon, Chia Chia Liu, Xiang H.-F. Zhang, C. Kent Osborne, Mothaffar F. Rimawi, Jamunarani Veeraraghavan, Rachel Schiff
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 386.
https://doi.org/10.1158/1538-7445.AM2023-386
Published: 04 April 2023
View article titled, Abstract 386: Metastatic models of resistance to next generation tyrosine kinase inhibitors (TKIs) in HER2-positive breast cancer (BC)
Journal Articles

Single-Cell Analysis Unveils the Role of the Tumor Immune Microenvironment and Notch Signaling in Dormant Minimal Residual Disease

Mahnaz Janghorban, Yuchen Yang, Na Zhao, Clark Hamor, Tuan M. Nguyen, Xiang H.-F. Zhang, Jeffrey M. Rosen
Journal: Cancer Research
Cancer Res (2022) 82 (5): 885–899.
https://doi.org/10.1158/0008-5472.CAN-21-1230
Published: 03 March 2022
View article titled, Single-Cell Analysis Unveils the Role of the Tumor Immune Microenvironment and Notch Signaling in Dormant Minimal Residual Disease
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Includes: Supplementary data
Journal Articles

A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis

Fei Yue, Weiyu Jiang, Amy T. Ku, Adelaide I.J. Young, Weijie Zhang, Eric P. Souto, Yankun Gao, Zihan Yu, Yi Wang, Chad J. Creighton, Chandandeep Nagi, Tao Wang, Susan G. Hilsenbeck, Xin-Hua Feng, Shixia Huang, Cristian Coarfa, Xiang H.-F. Zhang, Qingyun Liu, Xia Lin, Yi Li
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4441–4454.
https://doi.org/10.1158/0008-5472.CAN-21-1112
Published: 01 September 2021
View article titled, A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
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Includes: Supplementary data
Journal Articles

Abstract PD15-03: LGR4 engages a wnt-independent mechanism to enhance EGFR signaling and promote metastasis of triple-negative breast cancer

Fei Yue, Weiyu Jiang, Amy T Ku, Adelaide IJ Young, Weijie Zhang, Eric P Souto, Yankun Gao, Zhihan Yu, Yi Wang, Chad J Creighton, Chandandeep Nagi, Tao Wang, Xin-Hua Feng, Shixia Huang, Cristian Coarfa, Xiang H.-F. Zhang, Qingyun Liu, Xia Lin, Yi Li
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD15-03.
https://doi.org/10.1158/1538-7445.SABCS20-PD15-03
Published: 15 February 2021
View article titled, Abstract PD15-03: LGR4 engages a wnt-independent mechanism to enhance EGFR signaling and promote metastasis of triple-negative breast cancer
Journal Articles

Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone

Abhisha Sawant Dessai, Mayrel Palestino Dominguez, Uan-I Chen, John Hasper, Christian Prechtl, Cuijuan Yu, Eriko Katsuta, Tao Dai, Bokai Zhu, Sung Yun Jung, Nagireddy Putluri, Kazuaki Takabe, Xiang H.-F. Zhang, Bert W. O'Malley, Subhamoy Dasgupta
Journal: Cancer Research
Cancer Res (2021) 81 (1): 50–63.
https://doi.org/10.1158/0008-5472.CAN-20-1708
Published: 04 January 2021
View article titled, Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone
Open the PDF for Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone in another window
Includes: Supplementary data
Journal Articles

Abstract P3-06-12: Autophagy-mediated survival mechanism to c-Src inhibitor therapy in triple negative breast cancer

Kwanghwa Jung, Junhyoung Park, Tirupataiah Sirupangi, Dongya Jia, Nishant Gandhi, Shivanand Pudakalakatti, Jessica Elswood, Weston Porter, Nagireddy Putluri, Xiang H.-F Zhang, Xi Chen, Pratip K. Bhattacharya, Chad J. Creighton, Michael T. Lewis, Jeffrey M. Rosen, Lee-Jun C. Wong, Gokul M. Das, C. Kent Osborne, Mothaffar F Rimawi, Benny Abraham Kaipparettu
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-06-12.
https://doi.org/10.1158/1538-7445.SABCS19-P3-06-12
Published: 15 February 2020
View article titled, Abstract P3-06-12: Autophagy-mediated survival mechanism to c-Src inhibitor therapy in triple negative breast cancer
Journal Articles

HER2/EGFR–AKT Signaling Switches TGFβ from Inhibiting Cell Proliferation to Promoting Cell Migration in Breast Cancer

Fei Huang, Qiaoni Shi, Yuzhen Li, Linlin Xu, Chi Xu, Fenfang Chen, Hai Wang, Hongwei Liao, Zai Chang, Fang Liu, Xiang H.-F. Zhang, Xin-Hua Feng, Jing-Dong J. Han, Shiwen Luo, Ye-Guang Chen
Journal: Cancer Research
Cancer Res (2018) 78 (21): 6073–6085.
https://doi.org/10.1158/0008-5472.CAN-18-0136
Published: 01 November 2018
View article titled, HER2/EGFR–AKT Signaling Switches TGFβ from Inhibiting Cell Proliferation to Promoting Cell Migration in Breast Cancer
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Includes: Supplementary data
Journal Articles

FGFR1-Activated Translation of WNT Pathway Components with Structured 5′ UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation

Tuan M. Nguyen, Elena B. Kabotyanski, Yongchao Dou, Lucas C. Reineke, Peng Zhang, Xiang H.-F. Zhang, Anna Malovannaya, Sung Yun Jung, Qianxing Mo, Kevin P. Roarty, Yiwen Chen, Bing Zhang, Joel R. Neilson, Richard E. Lloyd, Charles M. Perou, Matthew J. Ellis, Jeffrey M. Rosen
Journal: Cancer Research
Cancer Res (2018) 78 (15): 4229–4240.
https://doi.org/10.1158/0008-5472.CAN-18-0631
Published: 31 July 2018
View article titled, FGFR1-Activated Translation of WNT Pathway Components with Structured 5′ UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation
Open the PDF for FGFR1-Activated Translation of WNT Pathway Components with Structured 5′ UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation in another window
Includes: Supplementary data
Journal Articles

Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer

Ding Ren, Xiaoping Zhu, Ren Kong, Zhen Zhao, Jianting Sheng, Jiang Wang, Xiaoyun Xu, Jiyong Liu, Kemi Cui, Xiang H.-F. Zhang, Hong Zhao, Stephen T.C. Wong
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2052–2064.
https://doi.org/10.1158/0008-5472.CAN-17-2994
Published: 12 April 2018
View article titled, Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer
Open the PDF for Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer in another window
Journal Articles

Abstract LB-202: 14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2

Jia Xu, Sunil Acharya, Ozgur Sahin, Lin Zhang, Frank J. Lowery, Aysegul A. Sahin, Xiang H.-f. Zhang, Mien-Chie Hung, Dihua Yu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-202.
https://doi.org/10.1158/1538-7445.AM2015-LB-202
Published: 01 August 2015
View article titled, Abstract LB-202: 14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2