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Abstract 2678: LLL12B, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer cells

Li Pan, Xiang Chen, Feyruz V. Rassool, Chenglong Li, Jiayuh Lin

Cancer Res (2022) 82 (12_Supplement): 2678.

DOI: https://doi.org/10.1158/1538-7445.AM2022-2678

Published: 15 June 2022

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Journal Articles

Abstract 1936: MethylationToRegulation: A deep-learning approach to infer chromatin properties from DNA methylomes

Daniel K. Putnam, Brian J. Abraham, Xiang Chen

Cancer Res (2022) 82 (12_Supplement): 1936.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1936

Published: 15 June 2022

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Journal Articles

Abstract 6092: The dual roles of C-X-C MOTIF chemokine LIGAND 10 in pediatric osteosarcoma

Xiang Chen, Margaret Clement, John Hicks, Tsz Kwong Man

Cancer Res (2022) 82 (12_Supplement): 6092.

DOI: https://doi.org/10.1158/1538-7445.AM2022-6092

Published: 15 June 2022

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Journal Articles

Abstract PO-060: N-terminal RHAMM cooperates with dysfunctional p53 to accelerate the progression of pancreatic cancer

Anthony Lin, Jennifer Feng, Xiang Chen, Dunrui Wang, Megan Wong, George Zhang, Joseph Na, Tiantian Zhang, Zhengming Chen, Yao-Tseng Chen, Yi-Chieh Nancy Du

Cancer Res (2021) 81 (22_Supplement): PO-060.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PO-060

Published: 15 November 2021

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Journal Articles

Abstract 965: The role of LOX-mediated FAK phosphorylation in osteosarcoma metastasis

Xiang Chen, John M. Hicks, Poonam Sarkar, Waleed M. Gaber, Tsz-Kwong MAN

Cancer Res (2021) 81 (13_Supplement): 965.

DOI: https://doi.org/10.1158/1538-7445.AM2021-965

Published: 01 July 2021

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Journal Articles

Abstract LB-230: Nanotherapy targeting metastatic factor RHAMM^B-positive pancreatic neuroendocrine tumors

Seung Koo Lee, Xiang Chen, Yi-Chieh Nancy Du, Ching-Hsuan Tung

Cancer Res (2020) 80 (16_Supplement): LB-230.

DOI: https://doi.org/10.1158/1538-7445.AM2020-LB-230

Published: 15 August 2020

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Journal Articles

Abstract 6155: Pediatric rhabdomyosarcomas recapitulate the transcriptomic and epigenomic development of skeletal myogenesis

Anand G. Patel, Xiang Chen, Michael Clay, Brittney Gordon, Jim Houston, Asa Karlstrom, Jackie Norrie, Elizabeth Stewart, Michael Dyer

Cancer Res (2020) 80 (16_Supplement): 6155.

DOI: https://doi.org/10.1158/1538-7445.AM2020-6155

Published: 15 August 2020

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Journal Articles

Abstract 6576: DNA methylation reveals alternative promoter usage in genes critical to pediatric tumors

Justin Williams, Beisi Xu, Daniel Putnam, Xiang Chen

Cancer Res (2020) 80 (16_Supplement): 6576.

DOI: https://doi.org/10.1158/1538-7445.AM2020-6576

Published: 15 August 2020

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Journal Articles

Abstract 6149: An innovative integrated cloud-based data portal for orthotopic patient-derived xenografts (O-PDX) available through the Childhood Solid Tumor Network (CSTN)

Cancer Res (2020) 80 (16_Supplement): 6149.

DOI: https://doi.org/10.1158/1538-7445.AM2020-6149

Published: 15 August 2020

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Journal Articles

Abstract B10: Rhabdomyosarcoma requires MYC family genomic events to pathogenically subvert core-regulatory circuitry

Cancer Res (2020) 80 (14_Supplement): B10.

DOI: https://doi.org/10.1158/1538-7445.PEDCA19-B10

Published: 15 July 2020

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Journal Articles

Abstract P5-05-11: Novel small molecule STAT3 inhibitors induce apoptosis and suppress cell migration and tumor growth in triple-negative breast cancer cells

Li Pan, Xiang Chen, Shengling Fu, Chenglong Li, Hui-Wen Lo, Jiayuh Lin

Cancer Res (2020) 80 (4_Supplement): P5-05-11.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-P5-05-11

Published: 15 February 2020

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Journal Articles

Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition

Molly Gale, Yao Li, Jian Cao, Zongzhi Z. Liu, Marissa A. Holmbeck, Meiling Zhang, Sabine M. Lang, Lizhen Wu, Mariana Do Carmo, Swati Gupta, Keisuke Aoshima, Michael P. DiGiovanna, David F. Stern, David L. Rimm, Gerald S. Shadel, Xiang Chen, Qin Yan

Cancer Res (2020) 80 (3): 524–535.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-3985

Published: 03 February 2020

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Includes: Supplementary data

Journal Articles

Abstract 2876: p21-activated kinase 1 is a novel therapeutic target for metastatic osteosarcoma harboring p27 mislocalization

Xiang Chen, Justin Cates, Yuchen Du, Yun Jung Sung, Xiao-nan Lo, John Hicks, Tsz-Kwong Man

Cancer Res (2019) 79 (13_Supplement): 2876.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2876

Published: 01 July 2019

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Journal Articles

Abstract 3768: Single-cell characterization and lineage tracking of recurrent pediatric rhabdomyosarcoma

Anand G. Patel, Elizabeth Stewart, Michael Clay, Xiang Chen, Michael Dyer

Cancer Res (2019) 79 (13_Supplement): 3768.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3768

Published: 01 July 2019

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Journal Articles

Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Maged Zeineldin, Sara Federico, Xiang Chen, Beisi Xu, Elizabeth Stewart, Arlene Naranjo, Michael D. Hogarty, Michael A. Dyer

Cancer Res (2018) 78 (19_Supplement): IA18.

DOI: https://doi.org/10.1158/1538-7445.PEDCA17-IA18

Published: 01 October 2018

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Journal Articles

Abstract PR11: Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma

Maged Zeineldin, Sara M. Federico, Lyra Griffith, Jongyre Jeon, Xiang Chen, John Easton, Jianrong Wu, Shenghua Mao, Yanling Liu, Arlene Naranjo, Alberto S. Pappo, Michael D. Hogarty, Michael A. Dyer

Cancer Res (2018) 78 (19_Supplement): PR11.

DOI: https://doi.org/10.1158/1538-7445.PEDCA17-PR11

Published: 01 October 2018

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Journal Articles

Abstract B26: Novel lncRNA regulates PAX3/FOXO1 expression and is essential for RMS tumorigenesis

Xiang Chen, Mireya Herrera-Herrera, Justina McEvoy

Cancer Res (2018) 78 (19_Supplement): B26.

DOI: https://doi.org/10.1158/1538-7445.PEDCA17-B26

Published: 01 October 2018

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Journal Articles

Abstract 3007: Monogenic and polygenic associations with subsequent breast cancer risk in survivors of childhood cancer: The St. Jude Lifetime Cohort Study (SJLIFE)

Cancer Res (2018) 78 (13_Supplement): 3007.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3007

Published: 01 July 2018

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Journal Articles

Abstract 864: Repurposing FDA-approved drug bazedoxifene as a novel inhibitor of IL-6 signaling for triple-negative breast cancer

Xiang Chen, Shengling Fu, Jilai Tian, Yang Cao, Chenglong Li, Jiayuh Lin

Cancer Res (2018) 78 (13_Supplement): 864.

DOI: https://doi.org/10.1158/1538-7445.AM2018-864

Published: 01 July 2018

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Journal Articles

Abstract 5297: LCA: A robust and scalable algorithm to reveal subtle diversity in large-scale single-cell RNA-Seq data

Changde Cheng, John Easton, Celeste Rosencrance, Yan Li, Bensheng Ju, Wenan Chen, Xiang Chen

Cancer Res (2018) 78 (13_Supplement): 5297.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5297

Published: 01 July 2018

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NARROW

Abstract 2678: LLL12B, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer cells

Abstract 1936: MethylationToRegulation: A deep-learning approach to infer chromatin properties from DNA methylomes

Abstract 6092: The dual roles of C-X-C MOTIF chemokine LIGAND 10 in pediatric osteosarcoma

Abstract PO-060: N-terminal RHAMM cooperates with dysfunctional p53 to accelerate the progression of pancreatic cancer

Abstract 965: The role of LOX-mediated FAK phosphorylation in osteosarcoma metastasis

Abstract LB-230: Nanotherapy targeting metastatic factor RHAMM^B-positive pancreatic neuroendocrine tumors

Abstract 6155: Pediatric rhabdomyosarcomas recapitulate the transcriptomic and epigenomic development of skeletal myogenesis

Abstract 6576: DNA methylation reveals alternative promoter usage in genes critical to pediatric tumors

Abstract 6149: An innovative integrated cloud-based data portal for orthotopic patient-derived xenografts (O-PDX) available through the Childhood Solid Tumor Network (CSTN)

Abstract B10: Rhabdomyosarcoma requires MYC family genomic events to pathogenically subvert core-regulatory circuitry

Abstract P5-05-11: Novel small molecule STAT3 inhibitors induce apoptosis and suppress cell migration and tumor growth in triple-negative breast cancer cells

Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition

Abstract 2876: p21-activated kinase 1 is a novel therapeutic target for metastatic osteosarcoma harboring p27 mislocalization

Abstract 3768: Single-cell characterization and lineage tracking of recurrent pediatric rhabdomyosarcoma

Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Abstract PR11: Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma

Abstract B26: Novel lncRNA regulates PAX3/FOXO1 expression and is essential for RMS tumorigenesis

Abstract 3007: Monogenic and polygenic associations with subsequent breast cancer risk in survivors of childhood cancer: The St. Jude Lifetime Cohort Study (SJLIFE)

Abstract 864: Repurposing FDA-approved drug bazedoxifene as a novel inhibitor of IL-6 signaling for triple-negative breast cancer

Abstract 5297: LCA: A robust and scalable algorithm to reveal subtle diversity in large-scale single-cell RNA-Seq data

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