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Journal Articles

Abstract 1924: Urine extracellular vesicles derived CA9 and CIZ1 as non-invasive biomarkers for early diagnosis of clear cell renal cell carcinoma

Xiyi Wei, Xi Zhang, Xinghan Yan, Zijie Yu, Weiyu Kong, Yize Li, Chao Qin, Hongwei Liang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1924.
https://doi.org/10.1158/1538-7445.AM2025-1924
Published: 21 April 2025
View articletitled, Abstract 1924: Urine extracellular vesicles derived CA9 and CIZ1 as non-invasive biomarkers for early diagnosis of clear cell renal cell carcinoma
Journal Articles

Abstract 873: 2-deoxy-D-glucose sensitizes the antigen recognition of chimeric antigen receptor-expressing tumor-infiltrating lymphocytes toward hepatocellular carcinoma cells

Mingyu Liu, Deping Han, Jean-Paul Thiery, Xi Zhang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 873.
https://doi.org/10.1158/1538-7445.AM2025-873
Published: 21 April 2025
View articletitled, Abstract 873: 2-deoxy-D-glucose sensitizes the antigen recognition of chimeric antigen receptor-expressing tumor-infiltrating lymphocytes toward hepatocellular carcinoma cells
Journal Articles

Abstract 3111: PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors

Xu Zhang, Jiao Xu, Xuan Wang, Lan Xu, Xi Zhang, Yi Wang, Shujuan Jiang, Yixiang Zhang, Jian Ding, Chen Qing, Linghua Meng
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3111.
https://doi.org/10.1158/1538-7445.AM2025-3111
Published: 21 April 2025
View articletitled, Abstract 3111: PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors
Journal Articles

Abstract 3489: Functional enhancement of hypoxia-activated chimeric antigen receptor T-cells by a chimeric switch receptor recognizing TGF-β

Zhihong Huang, Deping Han, Jean-Paul Thiery, Xi Zhang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3489.
https://doi.org/10.1158/1538-7445.AM2025-3489
Published: 21 April 2025
View articletitled, Abstract 3489: Functional enhancement of hypoxia-activated chimeric antigen receptor T-cells by a chimeric switch receptor recognizing TGF-β
Journal Articles

Abstract 5373: Intact regulation of G1/S transition renders esophageal squamous cell carcinomas sensitive to PI3Kα inhibitors by blocking SKP2-mediated p21 degradation

Yuxiang Wang, Xu Zhang, Xi Zhang, Yanyan Shen, Qingyang Ma, Yuemei Qiao, Yi Wang, Biyu Yang, Lan Xu, Gaoxiang Ge, Landian Hu, Xiangyin Kong, Chunhao Yang, Jian Ding, Yi Chen, Linghua Meng
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5373.
https://doi.org/10.1158/1538-7445.AM2022-5373
Published: 15 June 2022
View articletitled, Abstract 5373: Intact regulation of G1/S transition renders esophageal squamous cell carcinomas sensitive to PI3Kα inhibitors by blocking SKP2-mediated p21 degradation
Journal Articles

Abstract CT196: Early results of a safety and efficacy study of allogeneic TruUCAR™ GC502 in patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL)

Shiqi Li, Xinxin Wang, Zhongtao Yuan, Lin Liu, Yu Li, Jia Liu, Jiaping He, Zhimin Li, Wei Zhao, Jianning Ge, Yajin Ni, Lianjun Shen, Wei Cao, Xi Zhang, Martina Sersch, Sanbin Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT196.
https://doi.org/10.1158/1538-7445.AM2022-CT196
Published: 15 June 2022
View articletitled, Abstract CT196: Early results of a safety and efficacy study of allogeneic TruUCAR™ GC502 in patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL)
Journal Articles

Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu, Hongquan Zhang
Journal: Cancer Research
Cancer Res (2022) 82 (4): 735.
https://doi.org/10.1158/0008-5472.CAN-21-4346
Published: 15 February 2022
View articletitled, Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer
Open the PDF for Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer in another window
Journal Articles

Abstract LB147: Updates on clinical safety and efficacy result of GC027, the first-in-human, “Off-the-Shelf” CD7 CAR-T stand-alone therapy for adult patients with relapsed/refractory T-cell lymphoblastic leukemia (r/r T-ALL)

Shiqi Li, Lei Gao, Zhongtao Yuan, Kun Wu, Lin Liu, Le Luo, Yao Liu, Cheng Zhang, Yu Li, Duanpeng Wang, Zhimin Li, Xu Tan, Ruihao Huang, Dingsong Zhang, Youcheng Wang, Xinxin Wang, Jia Liu, Martina Sersch, Sanbin Wang, Xi Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB147.
https://doi.org/10.1158/1538-7445.AM2021-LB147
Published: 01 July 2021
View articletitled, Abstract LB147: Updates on clinical safety and efficacy result of GC027, the first-in-human, “Off-the-Shelf” CD7 CAR-T stand-alone therapy for adult patients with relapsed/refractory T-cell lymphoblastic leukemia (r/r T-ALL)
Journal Articles

Abstract 272: Glycomics: Protein glycosylation changes in the pathogenesis of head and neck cancer

Mohammad Rasheduzzaman, Xi Zhang, Riccardo Dolcetti, Liz Kenny, Newell W. Johnson, Daniel Kolarich, Chamindie Punyadeera
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 272.
https://doi.org/10.1158/1538-7445.AM2021-272
Published: 01 July 2021
View articletitled, Abstract 272: Glycomics: Protein glycosylation changes in the pathogenesis of head and neck cancer
Journal Articles

Abstract 602: Prognostic utility of circulating tumor cells/cell clusters in head and neck cancers

Xi Zhang, Kai Tang, Brett Hughes, Sarj Vasani, Zhen Liu, Majid Warkiani, Gunter Hartel, Rahul Ladwa, Liz Kenny, Chamindie Punyadeera
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 602.
https://doi.org/10.1158/1538-7445.AM2021-602
Published: 01 July 2021
View articletitled, Abstract 602: Prognostic utility of circulating tumor cells/cell clusters in head and neck cancers
Journal Articles

Abstract CT052: Clinical safety and efficacy study of TruUCAR™ GC027: The first-in-human, universal CAR-T therapy for adult relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL)

Xinxin Wang, Shiqi Li, Lei Gao, Zhongtao Yuan, Kun Wu, Lin Liu, Le Luo, Yao Liu, Cheng Zhang, Jia Liu, Chunhui Yang, Yu Li, Zhimin Li, Jiaping He, Duanpeng Wang, Xun Ye, Xu Tan, Ruihao Huang, Jianning Ge, Yu Han, Dingsong Zhang, Youcheng Wang, Lihua Fang, Yingnian Chen, Wei Cao, Sanbin Wang, Xi Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT052.
https://doi.org/10.1158/1538-7445.AM2020-CT052
Published: 15 August 2020
View articletitled, Abstract CT052: Clinical safety and efficacy study of TruUCAR™ GC027: The first-in-human, universal CAR-T therapy for adult relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL)
Journal Articles

The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu, Hongquan Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (13): 2737–2750.
https://doi.org/10.1158/0008-5472.CAN-19-3326
Published: 02 July 2020
View articletitled, The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer
Open the PDF for The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 739: Whole-exome sequencing of neuroendocrine neoplasm of the liver reveals recurrent mutations in components of RTK-RAS pathways

Lingli Chen, Yuan Ji, Jing Zhao, Lingtong Hao, Yixue Li, Xi Zhang, Huichuan Sun, Rongkui Luo, Jing Han, Jie Huang, Yingyong Hou, Jia Liu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 739.
https://doi.org/10.1158/1538-7445.AM2019-739
Published: 01 July 2019
View articletitled, Abstract 739: Whole-exome sequencing of neuroendocrine neoplasm of the liver reveals recurrent mutations in components of RTK-RAS pathways
Journal Articles

Abstract LB-268: Discovery of clinical candidate methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) : A highly potent and selective PI3K alpha inhibitor for the treatment of advanced solid tumors

Haoyue Xiang, Xiang Wang, Yanhong Chen, Xi Zhang, Yi Chen, Cun Tan, Yi Wang, Jian Ding, Ling-Hua Meng, Chunhao Yang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-268.
https://doi.org/10.1158/1538-7445.AM2018-LB-268
Published: 01 July 2018
View articletitled, Abstract LB-268: Discovery of clinical candidate methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) : A highly potent and selective PI3K alpha inhibitor for the treatment of advanced solid tumors
Journal Articles

CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion

Xuanmao Jiao, Marco A. Velasco-Velázquez, Min Wang, Zhiping Li, Hallgeir Rui, Amy R. Peck, James E. Korkola, Xuelian Chen, Shaohua Xu, James B. DuHadaway, Sandra Guerrero-Rodriguez, Sankar Addya, Daniela Sicoli, Zhaomei Mu, Gang Zhang, Andres Stucky, Xi Zhang, Massimo Cristofanilli, Alessandro Fatatis, Joe W. Gray, Jiang F. Zhong, George C. Prendergast, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2018) 78 (7): 1657–1671.
https://doi.org/10.1158/0008-5472.CAN-17-0915
Published: 01 April 2018
View articletitled, CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion
Open the PDF for CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion in another window
Includes: Supplementary data
Journal Articles

Abstract 4985: Notch1 as a key mediator in promoting advanced castration-resistant prostate cancer

Tanya Stoyanova, Claire Faltermeier, Bryan Smith, Andrew Goldstein, Xi Zhang, Justin Drake, John Lee, Sandra Orellana, Steven Blum, Donghui Cheng, Kenneth Pienta, Jiaoti Huang, Owen Witte
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4985.
https://doi.org/10.1158/1538-7445.AM2015-4985
Published: 01 August 2015
View articletitled, Abstract 4985: Notch1 as a key mediator in promoting advanced castration-resistant prostate cancer
Journal Articles

Abstract 2637: Examining the function of the serine protease, Granzyme B, in ALK-positive, anaplastic large cell lymphoma.

Joel D. Pearson, Katelynn Rowe, Kayla Thew, Jing xi Zhang, Spencer Freeman, Robert J. Ingham
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2637.
https://doi.org/10.1158/1538-7445.AM2013-2637
Published: 15 April 2013
View articletitled, Abstract 2637: Examining the function of the serine protease, Granzyme B, in ALK-positive, anaplastic large cell lymphoma.
Journal Articles

Abstract 488: Reprogramming cancer cells into terminal differentiation via induced pluripotency

Igor Matushansky, Xi Zhang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 488.
https://doi.org/10.1158/1538-7445.AM2011-488
Published: 15 April 2011
View articletitled, Abstract 488: Reprogramming cancer cells into terminal differentiation via induced pluripotency
Journal Articles

Abstract 2048: microRNA regulation of tissue factor expression in breast cancer cells

Xiao-Xi Zhang, Haijun Yu, Jessica R. Lou, Jie Zheng, Narcis-Ioan Popescu, Florea Lupu, Wei-Qun Ding
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2048.
https://doi.org/10.1158/1538-7445.AM10-2048
Published: 15 April 2010
View articletitled, Abstract 2048: microRNA regulation of tissue factor expression in breast cancer cells
Journal Articles

In Benign Barrett's Epithelial Cells, Acid Exposure Generates Reactive Oxygen Species That Cause DNA Double-Strand Breaks

Hui Ying Zhang, Kathy Hormi-Carver, Xi Zhang, Stuart J. Spechler, Rhonda F. Souza
Journal: Cancer Research
Cancer Res (2009) 69 (23): 9083–9089.
https://doi.org/10.1158/0008-5472.CAN-09-2518
Published: 30 November 2009
View articletitled, In Benign Barrett's Epithelial Cells, Acid Exposure Generates Reactive Oxygen Species That Cause DNA Double-Strand Breaks
Open the PDF for In Benign Barrett's Epithelial Cells, Acid Exposure Generates Reactive Oxygen Species That Cause DNA Double-Strand Breaks in another window