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Wytske M. van Weerden
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Journal Articles

Abstract 6786: Assessment of immune cell infiltration and cancer metastatic potential in Akura™ Immune Flow Chip - A microfluidic 3D spheroid system

Tamara Häfeli, Silas Riss, Christian Lohasz, Dzhansu Hasanova, Svenja Lützow, Lisa Hölting, Michal Rudnik, Franziska Linke, Wytske M van Weerden, Laure-Anne Ligeon, Andreas Hierlemann, Mario Modena, Olivier Frey
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6786.
https://doi.org/10.1158/1538-7445.AM2024-6786
Published: 22 March 2024
View article titled, Abstract 6786: Assessment of immune cell infiltration and cancer metastatic potential in Akura™ Immune Flow Chip - A microfluidic 3D spheroid system
Journal Articles

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture

Sanjiban Chakrabarty, William F. Quiros-Solano, Maayke M.P. Kuijten, Ben Haspels, Sandeep Mallya, Calvin Shun Yu Lo, Amr Othman, Cinzia Silvestri, Anja van de Stolpe, Nikolas Gaio, Hanny Odijk, Marieke van de Ven, Corrina M.A. de Ridder, Wytske M. van Weerden, Jos Jonkers, Ronald Dekker, Nitika Taneja, Roland Kanaar, Dik C. van Gent
Journal: Cancer Research
Cancer Res (2022) 82 (3): 510–520.
https://doi.org/10.1158/0008-5472.CAN-21-0799
Published: 01 February 2022
View article titled, A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture
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Includes: Supplementary data
Journal Articles

Abstract 3919: Liquid biopsy derived organoids as a potential platform for personalized cancer therapy in metastatic prostate cancer

Lisanne Mout, Lisanne F. van Dessel, Jaco Kraan, Anouk C. de Jong, Rui P. Neves, Sigrun Erkens-Schulze, Anieta M. Siewerts, Job van Riet, Ronald de Wit, Stefan Sleijfer, Paul Hamberg, Yorick Sandberg, Peter A. te Boekhorst, Harmen J. van de Werken, John W. Martens, Nikolas H. Stoecklein, Wytske M. van Weerden, Martijn P. Lolkema
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3919.
https://doi.org/10.1158/1538-7445.AM2020-3919
Published: 15 August 2020
View article titled, Abstract 3919: Liquid biopsy derived organoids as a potential platform for personalized cancer therapy in metastatic prostate cancer
Journal Articles

Abstract 157: Targeting distinct nodes of the PI3K/AKT/mTOR cascade in prostate cancer cells: impact on cell proliferation, apoptosis and pathway signaling

Rute B. Marques, Ashraf Aghai, Wendy Stam, Wytske M. van Weerden
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 157.
https://doi.org/10.1158/1538-7445.AM2017-157
Published: 01 July 2017
View article titled, Abstract 157: Targeting distinct nodes of the PI3K/AKT/mTOR cascade in prostate cancer cells: impact on cell proliferation, apoptosis and pathway signaling
Journal Articles

Abstract 255: Docetaxel inhibits testosterone mediated activation of the AR pathway by SLCO1B3

Ellen S. de Morree, Ashraf Aghai, Alice A. Gibson, Ron H.J. Mathijssen, Eric A.C. Wiemer, Alex Sparreboom, Wytske M. van Weerden, Ronald de Wit
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 255.
https://doi.org/10.1158/1538-7445.AM2016-255
Published: 15 July 2016
View article titled, Abstract 255: Docetaxel inhibits testosterone mediated activation of the AR pathway by SLCO1B3
Journal Articles

Abstract 316: Cabazitaxel antitumor activity in docetaxel-resistant patient-derived prostate cancer xenograft models.

Ellen S. de Morree, Corrina M.A. de Ridder, Herman Burger, Erik A.C. Wiemer, Ron H.J. Mathijssen, Ronald de Wit, Wytske M. van Weerden
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 316.
https://doi.org/10.1158/1538-7445.AM2013-316
Published: 15 April 2013
View article titled, Abstract 316: Cabazitaxel antitumor activity in docetaxel-resistant patient-derived prostate cancer xenograft models.
Journal Articles

Abstract 4770: Dual activity of abiraterone: CYP17 mediated androgen ablation and direct AR inhibition.

Matthijs J. Moll, Robert J. van Soest, Jinpei Kumagai, Ralph Graeser, Ian Hickson, Guido W. Jenster, Wytske M. van Weerden
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4770.
https://doi.org/10.1158/1538-7445.AM2013-4770
Published: 15 April 2013
View article titled, Abstract 4770: Dual activity of abiraterone: CYP17 mediated androgen ablation and direct AR inhibition.
Journal Articles

Intraprostatic Steroidogenic Enzymes – Response

Johannes Hofland, Wytske M. van Weerden, Guido Jenster, Fritz H. Schröder, Frank H. de Jong
Journal: Cancer Research
Cancer Res (2010) 70 (20): 8249–8250.
https://doi.org/10.1158/0008-5472.CAN-10-2476
Published: 13 October 2010
View article titled, Intraprostatic Steroidogenic Enzymes – Response
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Journal Articles

Evidence of Limited Contributions for Intratumoral Steroidogenesis in Prostate Cancer

Johannes Hofland, Wytske M. van Weerden, Natasja F.J. Dits, Jacobie Steenbergen, Geert J.L.H. van Leenders, Guido Jenster, Fritz H. Schröder, Frank H. de Jong
Journal: Cancer Research
Cancer Res (2010) 70 (3): 1256–1264.
https://doi.org/10.1158/0008-5472.CAN-09-2092
Published: 31 January 2010
View article titled, Evidence of Limited Contributions for Intratumoral Steroidogenesis in Prostate Cancer
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Includes: Supplementary data
Journal Articles

TMPRSS2:ERG Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen Receptor–Negative Prostate Cancer

Karin G. Hermans, Ronald van Marion, Herman van Dekken, Guido Jenster, Wytske M. van Weerden, Jan Trapman
Journal: Cancer Research
Cancer Res (2006) 66 (22): 10658–10663.
https://doi.org/10.1158/0008-5472.CAN-06-1871
Published: 15 November 2006
View article titled, <em>TMPRSS2:ERG</em> Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen Receptor–Negative Prostate Cancer
Open the PDF for <em>TMPRSS2:ERG</em> Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen Receptor–Negative Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Evolution of the Androgen Receptor Pathway during Progression of Prostate Cancer

Peter J.M. Hendriksen, Natasja F.J. Dits, Koichi Kokame, Antoine Veldhoven, Wytske M. van Weerden, Chris H. Bangma, Jan Trapman, Guido Jenster
Journal: Cancer Research
Cancer Res (2006) 66 (10): 5012–5020.
https://doi.org/10.1158/0008-5472.CAN-05-3082
Published: 16 May 2006
View article titled, Evolution of the Androgen Receptor Pathway during Progression of Prostate Cancer
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Includes: Supplementary data
Journal Articles

Androgen Deprivation of the Prohormone Convertase-310 Human Prostate Cancer Model System Induces Neuroendocrine Differentiation

Johan Jongsma, Monique H. Oomen, Marinus A. Noordzij, Wytske M. Van Weerden, Gerard J. M. Martens, Theodorus H. van der Kwast, Fritz H. Schröder, Gert J. van Steenbrugge
Journal: Cancer Research
Cancer Res (2000) 60 (3): 741–748.
Published: 01 February 2000
View article titled, Androgen Deprivation of the Prohormone Convertase-310 Human Prostate Cancer Model System Induces Neuroendocrine Differentiation
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Journal Articles

Differentially Expressed Genes in Androgen-dependent and -independent Prostate Carcinomas

Glenn T. G. Chang, Leen J. Blok, Martine Steenbeek, Jos Veldscholte, Wytske M. van Weerden, Gert J. van Steenbrugge, Albert O. Brinkmann
Journal: Cancer Research
Cancer Res (1997) 57 (18): 4075–4081.
Published: 01 September 1997
View article titled, Differentially Expressed Genes in Androgen-dependent and -independent Prostate Carcinomas
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