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Wolfgang E. Berdel
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Journal Articles

Abstract 824: Comparative pharmacokinetics (PK) of targeted tissue factor tTF-NGR when intravenously applied alone or in combination with preceding trabectedin

Free
Christian Schwöppe, Caroline Brand, Kathrin Hessling, Heike Hintelmann, Andrew F. Berdel, Georg Lenz, Torsten Kessler, Manfred Fobker, Christoph Schliemann, Wolfgang E. Berdel
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 824.
https://doi.org/10.1158/1538-7445.AM2025-824
Published: 21 April 2025
View articletitled, Abstract 824: Comparative pharmacokinetics (PK) of targeted tissue factor tTF-NGR when intravenously applied alone or in combination with preceding trabectedin
Journal Articles

Abstract 4606: Combinatorial effects of a sequence of trabectedin (T) and CD13-targeted tissue factor tTF-NGR on human vascular endothelial cells (HUVEC) and in soft tissue sarcoma (STS) models

Free
Caroline Brand, Stefanie Pavelka, Kathrin Hessling, Heike Hintelmann, Andrew F. Berdel, Sebastian Bäumer, Nicole Bäumer, Georg Lenz, Christoph Schliemann, Wolfgang E. Berdel, Christian Schwöppe
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4606.
https://doi.org/10.1158/1538-7445.AM2024-4606
Published: 22 March 2024
View articletitled, Abstract 4606: Combinatorial effects of a sequence of trabectedin (T) and CD13-targeted tissue factor tTF-NGR on human vascular endothelial cells (HUVEC) and in soft tissue sarcoma (STS) models
Journal Articles

Abstract 3182: CAR T cells as micropharmacies to induce locoregional tumor vascular infarction by antigen-specific delivery of tissue factor to the tumor microenvironment

Free
Bianca Altvater, Sareetha Kailayangiri, Christian Spurny, Maike Flügge, Jutta Meltzer, Lea Greune, Christian Schwöppe, Caroline Brand, Christoph Schliemann, Wolfgang Hartmann, Hinrich Abken, Axel Schambach, Nicole Farwick, Wolfgang E. Berdel, Claudia Rossig
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3182.
https://doi.org/10.1158/1538-7445.AM2023-3182
Published: 04 April 2023
View articletitled, Abstract 3182: CAR T cells as micropharmacies to induce locoregional tumor vascular infarction by antigen-specific delivery of tissue factor to the tumor microenvironment
Journal Articles

Abstract LB-223: Intratumoral accumulation/entrapment of doxorubicin by tumor vascular infarction with retargeted tissue factor tTF-NGR

Free
Janine Stucke-Ring, Julian Timo Ronnacker, Caroline Brand, Verena Mantke, Carsten Höltke, Christoph Schliemann, Torsten Kessler, Rolf M. Mesters, Christian Schwöppe, Wolfgang E. Berdel
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-223.
https://doi.org/10.1158/1538-7445.AM2016-LB-223
Published: 15 July 2016
View articletitled, Abstract LB-223: Intratumoral accumulation/entrapment of doxorubicin by tumor vascular infarction with retargeted tissue factor tTF-NGR
Journal Articles

Abstract 2629: Site-directed and random PEGylation of retargeted tissue factor can improve the activity/toxicity profile of the molecule

Free
Caroline Zerbst, Janine Ring, Max Fröhlich, Christoph Schliemann, Rolf M. Mesters, Wolfgang E. Berdel, Christian Schwöppe
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2629.
https://doi.org/10.1158/1538-7445.AM2015-2629
Published: 01 August 2015
View articletitled, Abstract 2629: Site-directed and random PEGylation of retargeted tissue factor can improve the activity/toxicity profile of the molecule
Journal Articles

Abstract 4430: Loss of the histone methyltransferase EZH2 induces chemoresistance in acute myeloid leukemia (AML)

Free
Stefanie Göllner, Shuchi Agrawal-Singh, Tino Schenk, Hans-Ulrich Klein, Christian Rohde, Tim Sauer, Mads Lerdrup, Sigal Tavor, Friedrich Stölzel, Gerhard Ehninger, Gabriele Köhler, Martin Dugas, Arthur Zelent, Christian Thiede, Wolfgang E. Berdel, Klaus Hansen, Carsten Müller-Tidow
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4430.
https://doi.org/10.1158/1538-7445.AM2015-4430
Published: 01 August 2015
View articletitled, Abstract 4430: Loss of the histone methyltransferase EZH2 induces chemoresistance in acute myeloid leukemia (AML)
Journal Articles

Abstract 1766: Growth modulation of head and neck cancer via Sgk-1 inhibition: a novel modality of local control

Free
Henrik O. Berdel, Hongyu Yin, Jun Liu, Chris Middleton, Nathan Yanasak, Rafik Abdelsayed, Wolfgang E. Berdel, Mahmood Mozaffari, Jack C. Yu, Babak Baban
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1766.
https://doi.org/10.1158/1538-7445.AM2014-1766
Published: 01 October 2014
View articletitled, Abstract 1766: Growth modulation of head and neck cancer via Sgk-1 inhibition: a novel modality of local control
Journal Articles

Abstract 2675: Optimization of antivascular tumor therapy with retargeted tissue factor proteins to improve the activity/toxicity profiles and therapeutic outcome

Free
Christian Schwöppe, Caroline Zerbst, Christoph Schliemann, Rolf M. Mesters, Wolfgang E. Berdel
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2675.
https://doi.org/10.1158/1538-7445.AM2014-2675
Published: 01 October 2014
View articletitled, Abstract 2675: Optimization of antivascular tumor therapy with retargeted tissue factor proteins to improve the activity/toxicity profiles and therapeutic outcome
Journal Articles

Pim2 cooperates with PML-RARα to induce acute myeloid leukemia by enhancing genomic instability

Free
Shuchi Agrawal, Steffen Koschmieder, Nicole Baumer, Wolfgang E. Berdel, Carsten Muller-Tidow, Hubert Serve
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2980.
Published: 01 May 2008
View articletitled, Pim2 cooperates with PML-RARα to induce acute myeloid leukemia by enhancing genomic instability
Journal Articles

Adjuvant Therapy with Small Hairpin RNA Interference Prevents Non–Small Cell Lung Cancer Metastasis Development in Mice

Free
Etmar Bulk, Antje Hascher, Ruediger Liersch, Rolf M. Mesters, Sven Diederichs, Bülent Sargin, Volker Gerke, Marc Hotfilder, Josef Vormoor, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow
Journal: Cancer Research
Cancer Res (2008) 68 (6): 1896–1904.
https://doi.org/10.1158/0008-5472.CAN-07-2390
Published: 13 March 2008
View articletitled, Adjuvant Therapy with Small Hairpin RNA Interference Prevents Non–Small Cell Lung Cancer Metastasis Development in Mice
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Journal Articles

DNA Methylation of Tumor Suppressor Genes in Clinical Remission Predicts the Relapse Risk in Acute Myeloid Leukemia

Free
Shuchi Agrawal, Matthias Unterberg, Steffen Koschmieder, Udo zur Stadt, Uta Brunnberg, Walter Verbeek, Thomas Büchner, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow
Journal: Cancer Research
Cancer Res (2007) 67 (3): 1370–1377.
https://doi.org/10.1158/0008-5472.CAN-06-1681
Published: 05 February 2007
View articletitled, DNA Methylation of Tumor Suppressor Genes in Clinical Remission Predicts the Relapse Risk in Acute Myeloid Leukemia
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Includes: Supplementary data
Journal Articles

DNA methylation levels in clinical remission predict relapse in acute leukemia

Free
Carsten Müller-Tidow, Shuchi Agrawal, Matthias Unterberg, Steffen Koschmieder, Uta Brunnberg, Udo Zur Stadt, Wolfgang E. Berdel, Hubert Serve
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 760–761.
Published: 15 April 2006
View articletitled, DNA methylation levels in clinical remission predict relapse in acute leukemia
Journal Articles

Constitutive Activation of Akt by Flt3 Internal Tandem Duplications Is Necessary for Increased Survival, Proliferation, and Myeloid Transformation

Free
Christian H. Brandts, Bülent Sargin, Miriam Rode, Christoph Biermann, Beate Lindtner, Joachim Schwäble, Horst Buerger, Carsten Müller-Tidow, Chunaram Choudhary, Martin McMahon, Wolfgang E. Berdel, Hubert Serve
Journal: Cancer Research
Cancer Res (2005) 65 (21): 9643–9650.
https://doi.org/10.1158/0008-5472.CAN-05-0422
Published: 01 November 2005
View articletitled, Constitutive Activation of Akt by Flt3 Internal Tandem Duplications Is Necessary for Increased Survival, Proliferation, and Myeloid Transformation
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Journal Articles

Identification of Metastasis-Associated Receptor Tyrosine Kinases in Non–Small Cell Lung Cancer

Free
Carsten Müller-Tidow, Sven Diederichs, Etmar Bulk, Thorsten Pohle, Björn Steffen, Joachim Schwäble, Sylvia Plewka, Michael Thomas, Ralf Metzger, Paul M. Schneider, Christian H. Brandts, Wolfgang E. Berdel, Hubert Serve
Journal: Cancer Research
Cancer Res (2005) 65 (5): 1778–1782.
https://doi.org/10.1158/0008-5472.CAN-04-3388
Published: 07 March 2005
View articletitled, Identification of Metastasis-Associated Receptor Tyrosine Kinases in Non–Small Cell Lung Cancer
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Journal Articles

S100 Family Members and Trypsinogens Are Predictors of Distant Metastasis and Survival in Early-Stage Non-Small Cell Lung Cancer

Free
Sven Diederichs, Etmar Bulk, Björn Steffen, Ping Ji, Lara Tickenbrock, Kerstin Lang, Kurt S. Zänker, Ralf Metzger, Paul M. Schneider, Volker Gerke, Michael Thomas, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5564–5569.
https://doi.org/10.1158/0008-5472.CAN-04-2004
Published: 16 August 2004
View articletitled, S100 Family Members and Trypsinogens Are Predictors of Distant Metastasis and Survival in Early-Stage Non-Small Cell Lung Cancer
Open the PDF for S100 Family Members and Trypsinogens Are Predictors of Distant Metastasis and Survival in Early-Stage Non-Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Differences in the transforming capacity and signal transduction properties of Flt3-D835Y versus Flt3-ITD.

Free
Chunaram Choudhary, Joachim Schwäble, Wolfgang E. Berdel, Carsten Müller-Tidow, Hubert Serve
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 560.
Published: 01 April 2004
View articletitled, Differences in the transforming capacity and signal transduction properties of Flt3-D835Y versus Flt3-ITD.
Journal Articles

The novel growth suppressor FoCA1 (Friend of Cyclin A1) associates with pRb, contributes to the repression of E2F-dependent promoters and inhibits CDK2 kinase activity

Free
Sven Diederichs, Shuchi Agrawal, Nicole Bäumer, Sarah Pierschalski, Maria Möller, Kurt S. Zänker, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 600.
Published: 01 April 2004
View articletitled, The novel growth suppressor FoCA1 (Friend of Cyclin A1) associates with pRb, contributes to the repression of E2F-dependent promoters and inhibits CDK2 kinase activity
Journal Articles

Induction of PDGF-B expression in HUVECs by growth factors and conditioned medium derived from lung cancer cells.

Free
Niels Reinmuth, Sonja Rensinghoff, Heike Hintelmann, Guido Bisping, Frank Hilberg, Gerald J. Roth, Wolfgang E. Berdel, Michael Thomas, Rolf M. Mesters
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 829–830.
Published: 01 April 2004
View articletitled, Induction of PDGF-B expression in HUVECs by growth factors and conditioned medium derived from lung cancer cells.
Journal Articles

Overexpression of Basic Fibroblast Growth Factor and Autocrine Stimulation in Acute Myeloid Leukemia

Free
Ralf Bieker, Teresa Padró, Julia Kramer, Martin Steins, Torsten Kessler, Stephan Retzlaff, Federico Herrera, Joachim Kienast, Wolfgang E. Berdel, Rolf M. Mesters
Journal: Cancer Research
Cancer Res (2003) 63 (21): 7241–7246.
Published: 11 November 2003
View articletitled, Overexpression of Basic Fibroblast Growth Factor and Autocrine Stimulation in Acute Myeloid Leukemia
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Journal Articles

Cyclin E is the Only Cyclin-dependent Kinase 2-associated Cyclin that Predicts Metastasis and Survival in Early Stage Non-Small Cell Lung Cancer

Free
Carsten Müller-Tidow, Ralf Metzger, Katrin Kügler, Sven Diederichs, Gregory Idos, Michael Thomas, Barbara Dockhorn-Dworniczak, Paul M. Schneider, H. Phillip Koeffler, Wolfgang E. Berdel, Hubert Serve
Journal: Cancer Research
Cancer Res (2001) 61 (2): 647–653.
Published: 01 January 2001
View articletitled, Cyclin E is the Only Cyclin-dependent Kinase 2-associated Cyclin that Predicts Metastasis and Survival in Early Stage Non-Small Cell Lung Cancer
Open the PDF for Cyclin E is the Only Cyclin-dependent Kinase 2-associated Cyclin that Predicts Metastasis and Survival in Early Stage Non-Small Cell Lung Cancer in another window