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Journal Articles

Abstract 5533: YIV-906 could modulate nuclear factor of activated T-cells (NFAT) activity of T cells for immune checkpoint blockade therapy and CAR T-cell therapy

Wing Lam, Shwu-Huey Liu, Peikwen Cheng, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5533.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5533
Published: 15 June 2022
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Journal Articles

Abstract P6-06-16: Resveratrol enhanced chemosensitivity by reversing macrophage polarization in breast cancer

Isabella Wai Yin Cheuk, Jiawei Chen, Man Ting Siu, Sau Wing Lam, Jue Wang, Vivian Yvonne Shin, Ava Kwong
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-06-16.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P6-06-16
Published: 15 February 2020
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Journal Articles

Abstract 2252: YIV-906 (PHY906) enhanced the anti-tumor activity of immune checkpoint blockade therapy (Anti-PD1) against liver cancer by changing the tumor micro-environment associated with M1 macrophages infiltration

Wing Lam, Xiaochen Yang, Zaoli Jiang, Xue han, Fulan Guan, Rong Hu, Chang-Hua Xu, Wei Cai, William Cheng, Shwu-Huey Liu, Yuping Cai, Nicholas Rattray, Caroline Johnson, Lieping Chen, Yung-chi Cheng
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2252.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2252
Published: 01 July 2019
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Journal Articles

Abstract 2724: YIV906 (PHY906) enhanced the antitumor activity of immune checkpoint blockade therapy: Anti-PD1 against liver cancer

Wing Lam, XiaoChen Yang, Zaoli Jiang, Xue Han, Fulan Guan, William Cheng, Shwu-Huey Liu, Lieping Chen, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2724.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2724
Published: 01 July 2018
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Journal Articles

Abstract 5584: PHY906(YIV-906), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Immune checkpoint blockade therapy: anti-PDL1, anti-PD1, anti-PD1/CTLA4 against melanoma

Wing Lam, Zaoli jiang, Xue han, Shwu-Huey Liu, Lieping Chen, YungChi Cheng
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5584.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5584
Published: 01 July 2017
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Journal Articles

Abstract 3138: Mechanism based quality control (MBQC) for the four-herb Chinese medicine formulation, PHY906(YIV-906) and other herbal products

Wing Lam, Yongshen Ren, Fulan Guan, Zaoli jiang, William Cheng, Shwu-Huey Liu, YungChi Cheng
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3138.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3138
Published: 01 July 2017
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Journal Articles

Abstract #4584: Exploration of the mechanisms of PHY906 in reducing the intestinal toxicity caused by irinotecan

Wing Lam, Scott Bussom, Fulan Guan, Zaoli Jiang, Shwu-Huey Liu, YungChi Cheng
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4584.
Published: 01 May 2009
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Journal Articles

A novel herb-drug interaction: Irinotecan can significantly change the pharmacokinetics and pharmacodynamics of PHY906, a Chinese medicine formulation for cancer therapy

Min Ye, Zaoli Jiang, Wing Lam, Ginger Dutschman, Scott Bussom, Pei-chun Chen, Shwu-Huey Liu, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 635.
Published: 01 May 2008
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Journal Articles

The impact of hypoxia on the expression of Phosphoglycerate Kinase (PGK) and the Cytotoxicity of L-OddC (Troxacitabine) and dFdC (Gemcitabine) in H460 Cells, in vitro and in vivo.

Wing Lam, Scott Bussom, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3338.
Published: 01 May 2008
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Journal Articles

The impact of hypoxia treatment on the expression of PGK and the cytotoxicity of L-OddC (Troxacitabine) and dFdC (Gemcitabine)

Wing Lam, Scott Bussom, Chung-Hang Leung, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4044.
Published: 01 May 2007
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Journal Articles

PHY906 in hepatocellular carcinoma

Shwu-Huey Liu, Zaoli Jiang, Angeline Foo, Wing Lam, Min Ye, Yashang Lee, Duncan Liang, Susan Grill, Yun Yen, Michal Rose, Samuel So, Wasif Saif, Edward Chu, Robert Tilton, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1841.
Published: 01 May 2007
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Journal Articles

Alteration of UMP/CMP Kinase (GeneID: 51727, mRNA: AF087865) Amount is Not Solely Responsible for the Phosphorylation of Cellular Pyrimidine Nucleoside Monophosphates and Their Analog Monophosphates in Human RKO Cells

Rong Hu, Wing Lam, Susan P. Grill, Jieh-Yuan Liou, Chih-Hung Hsu, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 313.
Published: 15 April 2006
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Journal Articles

Eriocalyxin B selectively inhibits NF-κB activity by targeting multiple steps of the NF-κB activation pathway

Chung-Hang Leung, Susan P. Grill, Wing Lam, Han-Dong Sun, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 325.
Published: 15 April 2006
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Journal Articles

The effect of hypoxia treatment on the expression of phosphoglycerate kinase and apurine endonuclease-1 and its impact on the cytotoxicity of troxacitabine and gemcitabine

Wing Lam, Chung-Hang Leung, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 907.
Published: 15 April 2006
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Journal Articles

Potent inhibitory effect of a tylophorine analog DCB-3503 against NF-κB and its rapid induction of proteasomal degradation

Wenli Gao, Elizabeth Gullen, Her-Shyong Shiah, Wing Lam, Conrad Kaczmarek, David Baker, Zhinan Yin, Jin-Young Choi, Joseph Craft, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1096.
Published: 15 April 2006
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Journal Articles

Novel mechanism of inhibition of NF-κB DNA-binding activity by diterpenoids isolated from Isodon rubescens

Chung Hang Leung, Susan P. Grill, Wing Lam, Quan Bin Han, Han Dong Sun, Yung Chi Cheng
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 968.
Published: 01 May 2005
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Journal Articles

Human apurinic/apyrimidinic endonuclease (APE1) protein level is associated with the cytotoxicity of L-OddC but not Gemcitabine

Wing Lam, Chung-Hang Leung, Shin-Young Park, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1182.
Published: 01 May 2005
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Journal Articles

Cellular expression and localization of DNA exonucleases, Trex, and their response to chemotherapeutic compounds in different tumor cell lines

Chuan-Jen C. J. Wang, Guangwei Yang, Hua-Mei Chang, Wing Lam, Chih-Hung Hsu, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 418.
Published: 01 May 2005
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Journal Articles

Behaviors of DNA-exonucleases Trex1 and Trex2 in cells and their biochemical properties

Chuan-Jen C. Wang, Guangwei Yang, Hua-Mei Chang, Wing Lam, Fred W. Perrino, Yung-Chi Cheng
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 616.
Published: 01 April 2004
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Journal Articles

Reconstitution and characterization of dNTPs uptake activities of human mitochondrial adenine nucleotide translocators (Ant)

Wing Lam, Ee C. Cheng, Chung H. Leung, Yung C. Cheng
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 686.
Published: 01 April 2004
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