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William R. Greco
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Journal Articles

Rapamycin overcomes multidrug resistance (MDR) mediated by P-glycoprotein (Pgp), Multidrug Resistance Protein-1 (MRP-1), Breast Cancer Resistance Protein (BCRP) and Lung Resistance Protein (LRP) and synergizes with substrate drugs in MDR cells.

Free
Attaphol Pawarode, Hans Minderman, Kieran L. O’loughlin, William R. Greco, Maria R. Baer
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1270.
Published: 15 April 2006
View articletitled, Rapamycin overcomes multidrug resistance (MDR) mediated by P-glycoprotein (Pgp), Multidrug Resistance Protein-1 (MRP-1), Breast Cancer Resistance Protein (BCRP) and Lung Resistance Protein (LRP) and synergizes with substrate drugs in MDR cells.
Journal Articles

Modeling and analysis of drug concentration-effect and time course patterns in gene expression data from microarray experiments.

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Ram Varma, Suzanne Hector, Richard Mitchell, Lakshmi Pendyala, William R. Greco
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 21.
Published: 01 May 2005
View articletitled, Modeling and analysis of drug concentration-effect and time course patterns in gene expression data from microarray experiments.
Journal Articles

Gene expression profiling of a clonal isolate of A2780 ovarian carcinoma cell line

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Ram R. Varma, Suzanne M. Hector, William R. Greco, Lesleyann Hawthorn, Lakshmi Pendyala
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 379–380.
Published: 01 April 2004
View articletitled, Gene expression profiling of a clonal isolate of A2780 ovarian carcinoma cell line
Journal Articles

Photodynamic Therapy: A Means to Enhanced Drug Delivery to Tumors

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John W. Snyder, William R. Greco, David A. Bellnier, Lurine Vaughan, Barbara W. Henderson
Journal: Cancer Research
Cancer Res (2003) 63 (23): 8126–8131.
Published: 16 December 2003
View articletitled, Photodynamic Therapy: A Means to Enhanced Drug Delivery to Tumors
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Journal Articles

Treatment with the Tumor Necrosis Factor-α-Inducing Drug 5,6-Dimethylxanthenone-4-Acetic Acid Enhances the Antitumor Activity of the Photodynamic Therapy of RIF-1 Mouse Tumors

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David A. Bellnier, Sandra O. Gollnick, Susan H. Camacho, William R. Greco, Richard T. Cheney
Journal: Cancer Research
Cancer Res (2003) 63 (22): 7584–7590.
Published: 21 November 2003
View articletitled, Treatment with the Tumor Necrosis Factor-α-Inducing Drug 5,6-Dimethylxanthenone-4-Acetic Acid Enhances the Antitumor Activity of the Photodynamic Therapy of RIF-1 Mouse Tumors
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Journal Articles

Population Pharmacokinetics of the Photodynamic Therapy Agent 2-[1-Hexyloxyethyl]-2-devinyl Pyropheophorbide-a in Cancer Patients

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David A. Bellnier, William R. Greco, Gregory M. Loewen, Hector Nava, Allan R. Oseroff, Ravindra K. Pandey, Takaaki Tsuchida, Thomas J. Dougherty
Journal: Cancer Research
Cancer Res (2003) 63 (8): 1806–1813.
Published: 15 April 2003
View articletitled, Population Pharmacokinetics of the Photodynamic Therapy Agent 2-[1-Hexyloxyethyl]-2-devinyl Pyropheophorbide-a in Cancer Patients
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Journal Articles

Photofrin Photodynamic Therapy Can Significantly Deplete or Preserve Oxygenation in Human Basal Cell Carcinomas during Treatment, Depending on Fluence Rate

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Barbara W. Henderson, Theresa M. Busch, Lurine A. Vaughan, Noreen P. Frawley, Debra Babich, Tara A. Sosa, Joseph D. Zollo, Anthony S. Dee, Michele T. Cooper, David A. Bellnier, William R. Greco, Allan R. Oseroff
Journal: Cancer Research
Cancer Res (2000) 60 (3): 525–529.
Published: 01 February 2000
View articletitled, Photofrin Photodynamic Therapy Can Significantly Deplete or Preserve Oxygenation in Human Basal Cell Carcinomas during Treatment, Depending on Fluence Rate
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Journal Articles

Modeling of the Time-Dependency of in Vitro Drug Cytotoxicity and Resistance

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Laurence M. Levasseur, Harry K. Slocum, Youcef M. Rustum, William R. Greco
Journal: Cancer Research
Cancer Res (1998) 58 (24): 5749–5761.
Published: 01 December 1998
View articletitled, Modeling of the Time-Dependency of in Vitro Drug Cytotoxicity and Resistance
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Journal Articles

Super in Vitro Synergy between Inhibitors of Dihydrofolate Reductase and Inhibitors of Other Folate-requiring Enzymes: The Critical Role of Polyglutamylation

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Hélène M. Faessel, Harry K. Slocum, Robert C. Jackson, Theodore J. Boritzki, Youcef M. Rustum, M. G. Nair, William R. Greco
Journal: Cancer Research
Cancer Res (1998) 58 (14): 3036–3050.
Published: 01 July 1998
View articletitled, Super in Vitro Synergy between Inhibitors of Dihydrofolate Reductase and Inhibitors of Other Folate-requiring Enzymes: The Critical Role of Polyglutamylation
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Journal Articles

An in Vivo Quantitative Structure-Activity Relationship for a Congeneric Series of Pyropheophorbide Derivatives as Photosensitizers for Photodynamic Therapy

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Barbara W. Henderson, David A. Bellnier, William R. Greco, Amarnath Sharma, Ravindra K. Pandey, Lurine A. Vaughan, Kenneth R. Weishaupt, Thomas J. Dougherty
Journal: Cancer Research
Cancer Res (1997) 57 (18): 4000–4007.
Published: 01 September 1997
View articletitled, An in Vivo Quantitative Structure-Activity Relationship for a Congeneric Series of Pyropheophorbide Derivatives as Photosensitizers for Photodynamic Therapy
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Journal Articles

Lack of Reciprocity in Drug and Light Dose Dependence of Photodynamic Therapy of Pancreatic Adenocarcinoma in Vitro

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K. Thomas Moesta, William R. Greco, Stephen O. Nurse-Finlay, John C. Parsons, Thomas S. Mang
Journal: Cancer Research
Cancer Res (1995) 55 (14): 3078–3084.
Published: 01 July 1995
View articletitled, Lack of Reciprocity in Drug and Light Dose Dependence of Photodynamic Therapy of Pancreatic Adenocarcinoma in Vitro
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Journal Articles

Correspondence re: W. R. Greco et al., Application of a New Approach for the Quantitation of Drug Synergism to the Combination of cis-Diamminedichloroplatinum and 1-β-d-Arabinofuranosylcytosine. Cancer Res., 50: 5318–5327, 1990.—Reply

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William R. Greco, Youcef M. Rustum
Journal: Cancer Research
Cancer Res (1992) 52 (16): 4561–4565.
Published: 15 August 1992
View articletitled, Correspondence re: W. R. Greco et al., Application of a New Approach for the Quantitation of Drug Synergism to the Combination of cis-Diamminedichloroplatinum and 1-β-d-Arabinofuranosylcytosine. Cancer Res., 50: 5318–5327, 1990.—Reply
Open the PDF for Correspondence re: W. R. Greco et al., Application of a New Approach for the Quantitation of Drug Synergism to the Combination of cis-Diamminedichloroplatinum and 1-β-d-Arabinofuranosylcytosine. Cancer Res., 50: 5318–5327, 1990.—Reply in another window
Journal Articles

Quantitation of Folic Acid Enhancement of Antifolate Synergism

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Yvette Gaumont, Roy L. Kisliuk, John C. Parsons, William R. Greco
Journal: Cancer Research
Cancer Res (1992) 52 (8): 2228–2235.
Published: 01 April 1992
View articletitled, Quantitation of Folic Acid Enhancement of Antifolate Synergism
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Journal Articles

Application of a New Approach for the Quantitation of Drug Synergism to the Combination of cis-Diamminedichloroplatinum and 1-β-d-Arabinofuranosylcytosine1

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William R. Greco, Hyoung Sook Park, Youcef M. Rustum
Journal: Cancer Research
Cancer Res (1990) 50 (17): 5318–5327.
Published: 01 September 1990
View articletitled, Application of a New Approach for the Quantitation of Drug Synergism to the Combination of cis-Diamminedichloroplatinum and 1-β-d-Arabinofuranosylcytosine1
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Journal Articles

Relationship between DNA Ploidy, Glandular Differentiation, and Tumor Spread in Human Prostate Cancer

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Oskar S. Frankfurt, Joseph L. Chin, Lenore S. Englander, William R. Greco, J. Edson Pontes, Youcef M. Rustum
Journal: Cancer Research
Cancer Res (1985) 45 (3): 1418–1423.
Published: 01 March 1985
View articletitled, Relationship between DNA Ploidy, Glandular Differentiation, and Tumor Spread in Human Prostate Cancer
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Journal Articles

Toxicity and Pharmacokinetics of a New Antifolate, 2,4-Diamino-5-adamantyl-6-methylpyrimidine, in Dogs

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Sigmund F. Zakrzewski, Zlato Pavelic, William R. Greco, Gary Bullard, Patrick J. Creaven, Enrico Mihich
Journal: Cancer Research
Cancer Res (1982) 42 (6): 2177–2183.
Published: 01 June 1982
View articletitled, Toxicity and Pharmacokinetics of a New Antifolate, 2,4-Diamino-5-adamantyl-6-methylpyrimidine, in Dogs
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Journal Articles

Characterization of Cells Obtained by Mechanical and Enzymatic Means from Human Melanoma, Sarcoma, and Lung Tumors

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Harry K. Slocum, Zlatko P. Pavelic, Youcef M. Rustum, Patrick J. Creaven, Constantine Karakousis, Hiroshi Takita, William R. Greco
Journal: Cancer Research
Cancer Res (1981) 41 (4): 1428–1434.
Published: 01 April 1981
View articletitled, Characterization of Cells Obtained by Mechanical and Enzymatic Means from Human Melanoma, Sarcoma, and Lung Tumors
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Journal Articles

Antitumor Activity of Corynebacterium parvum and Retinyl Palmitate Used in Combination on the Lewis Lung Carcinoma

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Zlatko P. Pavelic, Sulochana Dave, Stanley Bialkowski, Roger L. Priore, William R. Greco
Journal: Cancer Research
Cancer Res (1980) 40 (12): 4617–4621.
Published: 01 December 1980
View articletitled, Antitumor Activity of Corynebacterium parvum and Retinyl Palmitate Used in Combination on the Lewis Lung Carcinoma
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