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Journal Articles

Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon

Julia Matas, Brendan Kohrn, Jeanne Fredrickson, Kelly Carter, Ming Yu, Ting Wang, Xianyong Gui, Thierry Soussi, Victor Moreno, William M. Grady, Miguel A. Peinado, Rosa Ana Risques

Cancer Res (2022) 82 (8): 1492–1502.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-3607

Published: 15 April 2022

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Includes: Supplementary data

Journal Articles

Abstract LB231: Somatic evolution in normal colon of patients with and without cancer

Júlia Matas Gironella, Brendan Kohrn, Jeanne Fredickson, Kelly Carter, Ting Wang, Ming Yu, William M Grady, Miguel Angel Peinado, Rosa Ana Risques

Cancer Res (2021) 81 (13_Supplement): LB231.

DOI: https://doi.org/10.1158/1538-7445.AM2021-LB231

Published: 01 July 2021

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Journal Articles

Abstract 477: Elevated EVL methylation level in the normal colon mucosa is a potential risk biomarker for developing metachronous polyps

Ming Yu, Ting Wang, Kelly T. Carter, Kelsey Baker, Mary W. Redman, Kathy Vickers, Lynda Ann Dzubinski, Robert E. Schoen, William M. Grady

Cancer Res (2021) 81 (13_Supplement): 477.

DOI: https://doi.org/10.1158/1538-7445.AM2021-477

Published: 01 July 2021

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Journal Articles

Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang, Baoyuan Huang, Shaoyong Peng, Meijin Huang, Guangwen Cao, Andrew M. Kaz, William M. Grady, Jianping Wang, Yanxin Luo

Cancer Res (2020) 80 (23): 5203–5215.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-1590

Published: 02 December 2020

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Includes: Supplementary data

Journal Articles

Abstract CT236: A phase 1b, multicenter, randomized, blinded, placebo-controlled study to evaluate the efficacy of guselkumab in subjects with familial adenomatous polyposis

Cancer Res (2020) 80 (16_Supplement): CT236.

DOI: https://doi.org/10.1158/1538-7445.AM2020-CT236

Published: 15 August 2020

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Journal Articles

Epigenetic Aging: More Than Just a Clock When It Comes to Cancer

Ming Yu, William D. Hazelton, Georg E. Luebeck, William M. Grady

Cancer Res (2020) 80 (3): 367–374.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-0924

Published: 03 February 2020

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Journal Articles

Implications of Epigenetic Drift in Colorectal Neoplasia

Georg E. Luebeck, William D. Hazelton, Kit Curtius, Sean K. Maden, Ming Yu, Kelly T. Carter, Wynn Burke, Paul D. Lampe, Christopher I. Li, Cornelia M. Ulrich, Polly A. Newcomb, Maria Westerhoff, Andrew M. Kaz, Yanxin Luo, John M. Inadomi, William M. Grady

Cancer Res (2019) 79 (3): 495–504.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1682

Published: 01 February 2019

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Includes: Supplementary data

Journal Articles

Abstract PR05: Using medical informatics to evaluate the risk of colorectal cancer in patients with clinically diagnosed sessile serrated polyps

Andrea Burnett-Hartman, Polly A. Newcomb, Chan X. Zeng, Yingye Zheng, John M. Inadomi, Christine Fong, Melissa P. Upton, William M. Grady

Cancer Res (2017) 77 (3_Supplement): PR05.

DOI: https://doi.org/10.1158/1538-7445.CRC16-PR05

Published: 31 January 2017

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Journal Articles

Abstract IA16: Current and emerging molecular diagnostic assays for colorectal cancer

William M. Grady

Cancer Res (2017) 77 (3_Supplement): IA16.

DOI: https://doi.org/10.1158/1538-7445.CRC16-IA16

Published: 31 January 2017

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Journal Articles

Abstract 1622: Assessment of candidate host “progression genes” in the development of advanced colorectal cancer

Stacey A. Cohen, Conghui Qu, Tabitha A. Harrison, Li Hsu, Polly A. Newcomb, Stephen B. Gruber, Stephane Bezieau, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Martha L. Slattery, Emily White, Ashley J. Vargas, Rami Nassir, Ulrike Peters, William M. Grady

Cancer Res (2016) 76 (14_Supplement): 1622.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1622

Published: 15 July 2016

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Journal Articles

Abstract 507: Prediction of colorectal cancer recurrence with plasma miRNAs in the ColoCare Study

Brandon Dickinson, Scott V. Adams, Cornelia Ulrich, Kathy Vickers, Michelle Wurscher, William M. Grady, Karen W. Makar

Cancer Res (2016) 76 (14_Supplement): 507.

DOI: https://doi.org/10.1158/1538-7445.AM2016-507

Published: 15 July 2016

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Journal Articles

Abstract 2292: Epigenetic alterations in Barrett's esophagus and esophageal adenocarcinoma: identification and evaluation of potential biomarkers

Rachele M. Stockdale, Andrew M. Kaz, Shelli M. Morris, Amitabh Chak, Joseph Willis, Dean Brenner, Sharmila Anandabapasathy, Maria Westerhoff, Chao-Jen Wong, Jill Barnholtz-Sloan, Yanwen Chen, William M. Grady

Cancer Res (2014) 74 (19_Supplement): 2292.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2292

Published: 01 October 2014

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Journal Articles

Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer

Stacey Meeker, Audrey Seamons, Jisun Paik, Piper M. Treuting, Thea Brabb, William M. Grady, Lillian Maggio-Price

Cancer Res (2014) 74 (16): 4398–4408.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-2820

Published: 13 August 2014

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Includes: Supplementary data

Journal Articles

Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas

Andrea N. Burnett-Hartman, Polly A. Newcomb, John D. Potter, Michael N. Passarelli, Amanda I. Phipps, Michelle A. Wurscher, William M. Grady, Lee-Ching Zhu, Melissa P. Upton, Karen W. Makar

Cancer Res (2013) 73 (9): 2863–2872.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-3462

Published: 30 April 2013

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Includes: Supplementary data

Journal Articles

Abstract 1166: Upregulation of microRNAs in colorectal tumors and association with disease stage.

Karen W. Makar, Michelle A. Wurscher, Nina Habermann, William M. Grady, Cornelia M. Ulrich

Cancer Res (2013) 73 (8_Supplement): 1166.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1166

Published: 15 April 2013

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Journal Articles

Abstract 1157: Increased expression of RecQ helicases in sporadic primary colorectal cancers

Victoria Valinluck Lao, Kelly T. Carter, Peter S. Rabinovitch, Piri Welcsh, William M. Grady

Cancer Res (2012) 72 (8_Supplement): 1157.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1157

Published: 15 April 2012

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Journal Articles

Abstract 1340: A mouse model of metastatic intestinal cancers associated with Fbw7- and p53-loss

Jonathan E. Grim, Sue Knoblaugh, Amanda Hagar, Jessica Hespelt, Jherek Swanger, Katherine Guthrie, Thomas Small, William M. Grady, Keiichi Nakayama, Bruce E. Clurman

Cancer Res (2012) 72 (8_Supplement): 1340.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1340

Published: 15 April 2012

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Journal Articles

Abstract 2415: TGF-ß signaling inactivation inhibits the formation of hepatocellular carcinomas induced by loss of p53

Shelli M. Morris, Ji Yeon Baek, Amanda Koszarek, Samornmas Kanngurn, Sue E. Knoblaugh, William M. Grady

Cancer Res (2011) 71 (8_Supplement): 2415.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2415

Published: 15 April 2011

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Journal Articles

Tumor Paint: A Chlorotoxin:Cy5.5 Bioconjugate for Intraoperative Visualization of Cancer Foci

Mandana Veiseh, Patrik Gabikian, S-Bahram Bahrami, Omid Veiseh, Miqin Zhang, Robert C. Hackman, Ali C. Ravanpay, Mark R. Stroud, Yumiko Kusuma, Stacey J. Hansen, Deborah Kwok, Nina M. Munoz, Raymond W. Sze, William M. Grady, Norman M. Greenberg, Richard G. Ellenbogen, James M. Olson

Cancer Res (2007) 67 (14): 6882–6888.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-3948

Published: 17 July 2007

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Includes: Supplementary data

Journal Articles

Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation

Nina M. Muñoz, Melissa Upton, Andres Rojas, M. Kay Washington, Li Lin, Anna Chytil, Elif G. Sozmen, Blair B. Madison, Ambra Pozzi, Randall T. Moon, Harold L. Moses, William M. Grady

Cancer Res (2006) 66 (20): 9837–9844.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-0890

Published: 17 October 2006

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NARROW

Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon

Abstract LB231: Somatic evolution in normal colon of patients with and without cancer

Abstract 477: Elevated EVL methylation level in the normal colon mucosa is a potential risk biomarker for developing metachronous polyps

Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer

Abstract CT236: A phase 1b, multicenter, randomized, blinded, placebo-controlled study to evaluate the efficacy of guselkumab in subjects with familial adenomatous polyposis

Epigenetic Aging: More Than Just a Clock When It Comes to Cancer

Implications of Epigenetic Drift in Colorectal Neoplasia

Abstract PR05: Using medical informatics to evaluate the risk of colorectal cancer in patients with clinically diagnosed sessile serrated polyps

Abstract IA16: Current and emerging molecular diagnostic assays for colorectal cancer

Abstract 1622: Assessment of candidate host “progression genes” in the development of advanced colorectal cancer

Abstract 507: Prediction of colorectal cancer recurrence with plasma miRNAs in the ColoCare Study

Abstract 2292: Epigenetic alterations in Barrett's esophagus and esophageal adenocarcinoma: identification and evaluation of potential biomarkers

Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer

Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas

Abstract 1166: Upregulation of microRNAs in colorectal tumors and association with disease stage.

Abstract 1157: Increased expression of RecQ helicases in sporadic primary colorectal cancers

Abstract 1340: A mouse model of metastatic intestinal cancers associated with Fbw7- and p53-loss

Abstract 2415: TGF-ß signaling inactivation inhibits the formation of hepatocellular carcinomas induced by loss of p53

Tumor Paint: A Chlorotoxin:Cy5.5 Bioconjugate for Intraoperative Visualization of Cancer Foci

Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation

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