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William G. Bornmann
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Journal Articles

Abstract 1727: Development of novel TAK1 inhibitors for pancreatic cancer

Paul J. Chiao, Zhuonan Zhuang, Qianghua Xia, Paul T. Schuber, Duoli Sun, Zhenghong Peng, David S. Maxwell, William G. Bornmann
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1727.
https://doi.org/10.1158/1538-7445.AM2014-1727
Published: 01 October 2014
View article titled, Abstract 1727: Development of novel TAK1 inhibitors for pancreatic cancer
Journal Articles

Abstract 2698: Degrasyn-like symmetrical compounds: Possible therapeutic agents for multiple myeloma (MM-I)

William G. Bornmann, Zhenghong Peng, David Maxwell, Duoli Sun, Basvoju A. Bhanu, Moshe Talpaz, Nicholas Donato, Alexander Levitzki
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2698.
https://doi.org/10.1158/1538-7445.AM2014-2698
Published: 01 October 2014
View article titled, Abstract 2698: Degrasyn-like symmetrical compounds: Possible therapeutic agents for multiple myeloma (MM-I)
Journal Articles

STAT3 Mediates Resistance to MEK Inhibitor through MicroRNA miR-17

Bingbing Dai, Jieru Meng, Michael Peyton, Luc Girard, William G. Bornmann, Lin Ji, John D. Minna, Bingliang Fang, Jack A. Roth
Journal: Cancer Research
Cancer Res (2011) 71 (10): 3658–3668.
https://doi.org/10.1158/0008-5472.CAN-10-3647
Published: 15 May 2011
View article titled, STAT3 Mediates Resistance to MEK Inhibitor through MicroRNA miR-17
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Includes: Supplementary data
Journal Articles

Abstract LB-400: STAT3 mediates resistance to MEK inhibitor through microRNA miR-17

Bingbing Dai, Jieru Meng, Michael Peyton, Luc Girard, William G. Bornmann, Lin Ji, John D. Minna, Bingliang Fang, Jack A. Roth
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-400.
https://doi.org/10.1158/1538-7445.AM2011-LB-400
Published: 15 April 2011
View article titled, Abstract LB-400: STAT3 mediates resistance to MEK inhibitor through microRNA miR-17
Journal Articles

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

Vaibhav Kapuria, Luke F. Peterson, Dexing Fang, William G. Bornmann, Moshe Talpaz, Nicholas J. Donato
Journal: Cancer Research
Cancer Res (2010) 70 (22): 9265–9276.
https://doi.org/10.1158/0008-5472.CAN-10-1530
Published: 14 November 2010
View article titled, Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis
Open the PDF for Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis in another window
Includes: Supplementary data
Journal Articles

β-Lapachone Micellar Nanotherapeutics for Non–Small Cell Lung Cancer Therapy

Elvin Blanco, Erik A. Bey, Chalermchai Khemtong, Su-Geun Yang, Jagadeesh Setti-Guthi, Huabing Chen, Chase W. Kessinger, Kevin A. Carnevale, William G. Bornmann, David A. Boothman, Jinming Gao
Journal: Cancer Research
Cancer Res (2010) 70 (10): 3896–3904.
https://doi.org/10.1158/0008-5472.CAN-09-3995
Published: 12 May 2010
View article titled, β-Lapachone Micellar Nanotherapeutics for Non–Small Cell Lung Cancer Therapy
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Includes: Supplementary data
Journal Articles

Sub-cellular compartmentalization of Jak2 as a unique mechanism for the inhibition of Jak2-Stat3 signaling

Vaibhav Kapuria, Geoffrey Bartholomeusz, Ling Y Kong, William G Bornmann, Nicholas J Donato
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2390.
Published: 01 May 2007
View article titled, Sub-cellular compartmentalization of Jak2 as a unique mechanism for the inhibition of Jak2-Stat3 signaling
Journal Articles

Aggresome Disruption: A Novel Strategy to Enhance Bortezomib-Induced Apoptosis in Pancreatic Cancer Cells

Steffan T. Nawrocki, Jennifer S. Carew, Maria S. Pino, Ralph A. Highshaw, Robert H.I. Andtbacka, Kenneth Dunner, Jr., Ashutosh Pal, William G. Bornmann, Paul J. Chiao, Peng Huang, Henry Xiong, James L. Abbruzzese, David J. McConkey
Journal: Cancer Research
Cancer Res (2006) 66 (7): 3773–3781.
https://doi.org/10.1158/0008-5472.CAN-05-2961
Published: 03 April 2006
View article titled, Aggresome Disruption: A Novel Strategy to Enhance Bortezomib-Induced Apoptosis in Pancreatic Cancer Cells
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Journal Articles

C. elegans ABL-1 functions similarly to Bcr-Abl and antagonizes p53-mediated germ cell apoptosis

Xinzhu Deng, Xianglei Yin, Darren R. Veach, Bayard Clarkson, William G. Bornmann, Zvi Fuks, Richard N. Kolesnick
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 196–197.
Published: 01 May 2005
View article titled, <em>C. elegans</em> ABL-1 functions similarly to Bcr-Abl and antagonizes p53-mediated germ cell apoptosis
Journal Articles

Searching for a better synthetic Lewis y (Ley) analogue to immunize patient with Ley positive cancers

Govind Ragupathi, Fusataka Koide, Maria Spassova, William G. Bornmann, Samuel J. Danishefsky, Philip O. Livingston
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1264–1265.
Published: 01 April 2004
View article titled, Searching for a better synthetic Lewis y (Le<sup>y</sup>) analogue to immunize patient with Le<sup>y</sup> positive cancers
Journal Articles

In vitro conditions promoting the formation of both microtubules and spirals by the natural product (-)-rhazinilam

Michael C. Edler, Guangli Yang, William G. Bornmann, Ernest Hamel
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1249–1250.
Published: 01 April 2004
View article titled, <em>In vitro</em> conditions promoting the formation of both microtubules and spirals by the natural product (-)-rhazinilam
Journal Articles

Inhibition of Wild-Type and Mutant Bcr-Abl by Pyrido-Pyrimidine-Type Small Molecule Kinase Inhibitors

Nikolas von Bubnoff, Darren R. Veach, W. Todd Miller, Wanqing Li, Jana Sänger, Christian Peschel, William G. Bornmann, Bayard Clarkson, Justus Duyster
Journal: Cancer Research
Cancer Res (2003) 63 (19): 6395–6404.
Published: 14 October 2003
View article titled, Inhibition of Wild-Type and Mutant Bcr-Abl by Pyrido-Pyrimidine-Type Small Molecule Kinase Inhibitors
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Journal Articles

Characterization of Potent Inhibitors of the Bcr-Abl and the c-Kit Receptor Tyrosine Kinases

David Wisniewski, Caryl L. Lambek, Chongyuan Liu, Annabel Strife, Darren R. Veach, Bhushan Nagar, Matthew A. Young, Thomas Schindler, William G. Bornmann, Joseph R. Bertino, John Kuriyan, Bayard Clarkson
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4244–4255.
Published: 01 August 2002
View article titled, Characterization of Potent Inhibitors of the Bcr-Abl and the c-Kit Receptor Tyrosine Kinases
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Journal Articles

Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571)

Bhushan Nagar, William G. Bornmann, Patricia Pellicena, Thomas Schindler, Darren R. Veach, W. Todd Miller, Bayard Clarkson, John Kuriyan
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4236–4243.
Published: 01 August 2002
View article titled, Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571)
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Journal Articles

Induction of Apoptosis in MCF-7:WS8 Breast Cancer Cells by β-Lapachone

Shelly M. Wuerzberger, John J. Pink, Sarah M. Planchon, Krista L. Byers, William G. Bornmann, David A. Boothman
Journal: Cancer Research
Cancer Res (1998) 58 (9): 1876–1885.
Published: 01 May 1998
View article titled, Induction of Apoptosis in MCF-7:WS8 Breast Cancer Cells by β-Lapachone
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