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William D. Figg
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Journal Articles

Abstract A045: Whole transcriptome analysis of paired African American prostate cancer cell lines

Kristi Y. Lee, Erica L. Beatson, Cindy H. Chau, Douglas K. Price, William D. Figg
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A045.
https://doi.org/10.1158/1538-7445.PRCA2023-A045
Published: 02 June 2023
View article titled, Abstract A045: Whole transcriptome analysis of paired African American prostate cancer cell lines
Journal Articles

Abstract A053: Epigenomic analyses of circulating tumor DNA in patients with metastatic castration resistant prostate cancer (mCRPC) treated with immune checkpoint blockade and PARP inhibition

Anna Baj, Clara C. Y. Seo, Nicholas T. Terrigino, John R. Bright, S. Thomas Hennigan, Isaiah M. King, Shana Y. Trostel, William D. Figg, William L. Dahut, Jung-Min Lee, David Y. Takeda, Fatima Karzai, Adam G. Sowalsky
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A053.
https://doi.org/10.1158/1538-7445.PRCA2023-A053
Published: 02 June 2023
View article titled, Abstract A053: Epigenomic analyses of circulating tumor DNA in patients with metastatic castration resistant prostate cancer (mCRPC) treated with immune checkpoint blockade and PARP inhibition
Journal Articles

Abstract B044: Exosomal cancer-type SLCO1B3 and ABCC3 as potential biomarkers of castration resistant prostate cancer

Erica L. Beatson, Kristi Y. Lee, Martina A. Knechel, Elijah R. Sommer, Roger Depaz, Emily N. Risdon, Andres F. Leon, Jonathan D. Strope, Douglas K. Price, Cindy H. Chau, William D. Figg
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B044.
https://doi.org/10.1158/1538-7445.PRCA2023-B044
Published: 02 June 2023
View article titled, Abstract B044: Exosomal cancer-type <em>SLCO1B3</em> and <em>ABCC3</em> as potential biomarkers of castration resistant prostate cancer
Journal Articles

Abstract B068: Treatment combinations targeting MCL-1 and BCL-xL exert synergistic anti-tumor effects in AR-V7 expressing CRPC cell lines

Giulia C. Napoli, Andres F. Leon, Erica L. Beatson, Keith T. Schmidt, Emily N. Risdon, Cindy H. Chau, Douglas K. Price, William D. Figg
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B068.
https://doi.org/10.1158/1538-7445.PRCA2023-B068
Published: 02 June 2023
View article titled, Abstract B068: Treatment combinations targeting MCL-1 and BCL-xL exert synergistic anti-tumor effects in AR-V7 expressing CRPC cell lines
Journal Articles

Abstract CT268: Targeting replication stress and chemotherapy resistance with a combination of sacituzumab govitecan and berzosertib: A phase I clinical trial

Melissa L. Abel, Nobukyuki Takahashi, Parth Desai, Cody Peer, Christophe Redon, Samantha Nichols, Rasa Vilimas, Min-Jung Lee, Sunmin Lee, Linda Sciuto, Danielle Pinkiert, Meenakshi Shelat, Chante Graham, Seth Steinberg, William D. Figg, Mirit Aladjem, Jane Trepel, Yves Pommier, Anish Thomas
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT268.
https://doi.org/10.1158/1538-7445.AM2023-CT268
Published: 14 April 2023
View article titled, Abstract CT268: Targeting replication stress and chemotherapy resistance with a combination of sacituzumab govitecan and berzosertib: A phase I clinical trial
Journal Articles

A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models

Shaun D. Fontaine, Gary W. Ashley, Peter J. Houghton, Raushan T. Kurmasheva, Morgan Diolaiti, Alan Ashworth, Cody J. Peer, Ryan Nguyen, William D. Figg, Sr., Denis R. Beckford-Vera, Daniel V. Santi
Journal: Cancer Research
Cancer Res (2021) 81 (4): 1076–1086.
https://doi.org/10.1158/0008-5472.CAN-20-1741
Published: 15 February 2021
View article titled, A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models
Open the PDF for A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models in another window
Includes: Supplementary data
Journal Articles

Abstract PR07: Phase I/II study of mesothelin-targeted immunotoxin LMB-100 with nab-paclitaxel for patients with advanced pancreatic adenocarcinoma

Christine C. Alewine, Mehwish Ahmad, Cody J. Peer, Zishuo Hu, Min-jung Lee, Akiro Yuno, Jessica Kindrick, Anish Thomas, Seth Steinberg, Jane B. Trepel, William D. Figg, Raffit Hassan, Ira Pastan
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): PR07.
https://doi.org/10.1158/1538-7445.PANCA19-PR07
Published: 13 December 2019
View article titled, Abstract PR07: Phase I/II study of mesothelin-targeted immunotoxin LMB-100 with nab-paclitaxel for patients with advanced pancreatic adenocarcinoma
Journal Articles

Abstract 2943: Severe hepatotoxicity of mithramycin therapy caused by altering expression of hepatocellular bile transporters

Tristan M. Sissung, Phoebe A. Huang, Ralph Hauke, Edel McCrea, Cody J. Peer, Roberto H. Barbier, Jonathan D. Strope, Ariel M. Ley, Mary Zhang, Julie A. Hong, David Venzon, Jonathan P. Jackson, Kenneth R. Brouwer, Patrick Grohar, John Glod, Brigitte C. Widemann, Theo Heller, David S. Schrump, William D. Figg
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2943.
https://doi.org/10.1158/1538-7445.AM2019-2943
Published: 01 July 2019
View article titled, Abstract 2943: Severe hepatotoxicity of mithramycin therapy caused by altering expression of hepatocellular bile transporters
Journal Articles

Abstract 14: Preclinical evaluation of novel HIF-1α/P300 binding inhibitors

Jonathan D. Strope, Emily M. Harris, Shaunna L. Beedie, Cindy H. Chau, Kristina M. Cook, Christopher J. Schofield, Kirk R. Gustafson, William D. Figg
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 14.
https://doi.org/10.1158/1538-7445.AM2018-14
Published: 01 July 2018
View article titled, Abstract 14: Preclinical evaluation of novel HIF-1α/P300 binding inhibitors
Journal Articles

Abstract 4330: Astrocytic S1P3 regulates blood-brain/tumor barrier permeability

Anurag N. Paranjape, Brunilde Gril, Stephan Woditschka, Emily Hua, Jeffrey C. Hanson, Xiaolin Wu, Renata Duchnowska, Priscilla K. Brastianos, David L. Liewehr, Seth M. Steinberg, Cody Peer, William D. Figg, Gary T. Pauly, Christina Robinson, Joel P. Schneider, Patricia S. Steeg
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4330.
https://doi.org/10.1158/1538-7445.AM2017-4330
Published: 01 July 2017
View article titled, Abstract 4330: Astrocytic S1P3 regulates blood-brain/tumor barrier permeability
Journal Articles

Abstract CT058: A phase 2 open-label study to evaluate the efficacy and safety of VT-464 in patients with androgen receptor positive triple-negative breast cancer patients, and men with ER positive breast cancer

Alexandra Zimmer, Margaret E. Gatti-Mays, Stan Lipkowitz, Fatima Karzai, James Gulley, William Dahut, Seth Steinberg, William D. Figg, Ravi Madan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT058.
https://doi.org/10.1158/1538-7445.AM2017-CT058
Published: 01 July 2017
View article titled, Abstract CT058: A phase 2 open-label study to evaluate the efficacy and safety of VT-464 in patients with androgen receptor positive triple-negative breast cancer patients, and men with ER positive breast cancer
Journal Articles

Abstract 1274: Associations between genetic polymorphisms in genes related to estrogen metabolism and function and prostate cancer risk: results from the Prostate Cancer Prevention Trial

Li Tang, Mary Platek, Song Yao, Cathee Till, Phyllis Goodman, Catherine M. Tangen, Yue Wu, Elizabeth A. Platz, Marian L. Neuhouse, Frank Z. Stanczyk, Juergen K. Reichardt, Regina M. Santella, Ann Hsing, William D. Figg, Scott M. Lippman, Ian M. Thompson, Christine B. Ambrosone
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1274.
https://doi.org/10.1158/1538-7445.AM2017-1274
Published: 01 July 2017
View article titled, Abstract 1274: Associations between genetic polymorphisms in genes related to estrogen metabolism and function and prostate cancer risk: results from the Prostate Cancer Prevention Trial
Journal Articles

Abstract 1794: Identification of novel single nucleotide polymorphisms (SNPs) associated with risk and prognosis in patients with castration-resistant prostate cancer (CRPC)

Tristan M. Sissung, Deeken John, Crystal R. Leibrand, Douglas K. Price, Sheryl Ehrlich, Seth M. Steinberg, David J. Liewehr, William L. Dahut, William D. Figg
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1794.
https://doi.org/10.1158/1538-7445.AM2016-1794
Published: 15 July 2016
View article titled, Abstract 1794: Identification of novel single nucleotide polymorphisms (SNPs) associated with risk and prognosis in patients with castration-resistant prostate cancer (CRPC)
Journal Articles

Abstract 2043: Effects of 24-h carboplatin pretreatment on olaparib clearance in women's cancers using noncompartmental and population pharmacokinetic analyses

Andrew K.L. Goey, Cody J. Peer, Tristan M. Sissung, Jeffrey Roth, Shandiz Shahbazi, Jeffers Nguyen, Christina M. Annunziata, Nicole Houston, Elise C. Kohn, Jung-Min Lee, William D. Figg
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2043.
https://doi.org/10.1158/1538-7445.AM2016-2043
Published: 15 July 2016
View article titled, Abstract 2043: Effects of 24-h carboplatin pretreatment on olaparib clearance in women's cancers using noncompartmental and population pharmacokinetic analyses
Journal Articles

Abstract 5480: Effects of UGT1A1 genotype on pharmacokinetics and toxicities of belinostat administered by continuous infusion in two clinical trials

Andrew K.L. Goey, Tristan M. Sissung, Cody J. Peer, Sheryl Ehrlich, Christina Bryla, Arlene W. Berman, Sanjeeve Balasubramaniam, Arun Rajan, Giuseppe Giaccone, Susan E. Bates, William D. Figg
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5480.
https://doi.org/10.1158/1538-7445.AM2015-5480
Published: 01 August 2015
View article titled, Abstract 5480: Effects of UGT1A1 genotype on pharmacokinetics and toxicities of belinostat administered by continuous infusion in two clinical trials
Journal Articles

Abstract 2546: Analysis of immune cell subsets in a multidrug therapeutic regimen for patients with metastatic castration-resistant prostate cancer

Caroline Jochems, Benjamin Boyerinas, Ravi A. Madan, Diane J. Poole, Yang-Min Ning, William D. Figg, David J. Liewehr, Seth M. Steinberg, James L. Gulley, Kwong-Yok Tsang, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2546.
https://doi.org/10.1158/1538-7445.AM2014-2546
Published: 01 October 2014
View article titled, Abstract 2546: Analysis of immune cell subsets in a multidrug therapeutic regimen for patients with metastatic castration-resistant prostate cancer
Journal Articles

Abstract 366: Translational modeling of docetaxel-thalidomide combination treatment in metastatic, castrate-resistant prostate cancer: predicting clinical response using preclinical data

Eric Fernandez, Hitesh Mistry, Frances Brightman, David Orrell, William L. Dahut, William D. Figg, Wilfried D. Stein, Christophe Chassagnole
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 366.
https://doi.org/10.1158/1538-7445.AM2014-366
Published: 01 October 2014
View article titled, Abstract 366: Translational modeling of docetaxel-thalidomide combination treatment in metastatic, castrate-resistant prostate cancer: predicting clinical response using preclinical data
Journal Articles

Abstract 1863: Androgen receptor CAG repeat length and TMPRSS2:ETS prostate cancer risk: results from the Prostate Cancer Prevention Trial

Douglas K. Price, Cindy H. Chau, William D. Figg, Catherine A. Till, Phyllis J. Goodman, Yonggon Cho, Marileila Garcia, Juergen Reichardt, Catherine M. Tangen, Robin J. Leach, Adrie van Bokhoven, Alan R. Kristal, Ian M. Thompson, M Scott Lucia
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1863.
https://doi.org/10.1158/1538-7445.AM2014-1863
Published: 01 October 2014
View article titled, Abstract 1863: Androgen receptor CAG repeat length and TMPRSS2:ETS prostate cancer risk: results from the Prostate Cancer Prevention Trial
Journal Articles

Abstract B29: A meta-analysis of racial disparities in the association between 8q24 and prostate cancer risk

Douglas K. Price, Sarah M. Troutman, Tristan M. Sissung, Cheryl Cropp, David J. Venzon, Shawn D. Spencer, William D. Figg
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): B29.
https://doi.org/10.1158/1538-7445.PRCA2012-B29
Published: 09 May 2013
View article titled, Abstract B29: A meta-analysis of racial disparities in the association between 8q24 and prostate cancer risk
Journal Articles

Abstract 1848: Expression of an androgen transporter, organic anion transporting polypeptide 1B3, impacts progression and treatment of prostate cancer

Heather M. Pressler, Tristan M. Sissung, Douglas K. Price, William D. Figg
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1848.
https://doi.org/10.1158/1538-7445.AM2012-1848
Published: 15 April 2012
View article titled, Abstract 1848: Expression of an androgen transporter, organic anion transporting polypeptide 1B3, impacts progression and treatment of prostate cancer