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Journal Articles

Macrophage-Derived Itaconate Suppresses Dendritic Cell Function to Promote Acquired Resistance to Anti–PD-1 Immunotherapy

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Xiao Yang, Yue Deng, Ying Ye, Jingshu Meng, Mengyao Su, Wenwen Wei, You Qin, Haibo Zhang, Yu Tian, Suke Deng, Zhiyun Liao, Zhiyuan Zhou, Jie Li, Yan Hu, Bin Zhang, Yajie Sun, Lu Wen, Zhanjie Zhang, Fang Huang, Chao Wan, Kunyu Yang
Journal: Cancer Research
Cancer Res (2025) 85 (10): 1842–1856.
https://doi.org/10.1158/0008-5472.CAN-24-2982
Published: 15 May 2025
View articletitled, Macrophage-Derived Itaconate Suppresses Dendritic Cell Function to Promote Acquired Resistance to Anti–PD-1 Immunotherapy
Open the PDF for Macrophage-Derived Itaconate Suppresses Dendritic Cell Function to Promote Acquired Resistance to Anti–PD-1 Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 854: Targeting Irg1 expressed on macrophages in lymph nodes promotes response to mRNA cancer vaccines

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Chao Wan, Wenwen Wei, Xiao Yang, Yeshan Chen, Mengjie Che, You Qin, Qiao Li, Kunyu Yang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 854.
https://doi.org/10.1158/1538-7445.AM2025-854
Published: 21 April 2025
View articletitled, Abstract 854: Targeting Irg1 expressed on macrophages in lymph nodes promotes response to mRNA cancer vaccines